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Evidence-based implementation of lifestyle medicine in healthcare practice: a research agenda. 生活方式医学在医疗保健实践中的循证实施:一个研究议程。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-09-01 DOI: 10.1136/fmch-2025-003324
Rimke C Vos, L A D M van Osch, J H M van Bilsen, M J Knapen, A W M Evers, M T E Hopman, L A L M Kiemeney, S Wopereis, Niels H Chavannes, Jessica C Kiefte-de Jong, Jochen Mierau, Stef Kremers
{"title":"Evidence-based implementation of lifestyle medicine in healthcare practice: a research agenda.","authors":"Rimke C Vos, L A D M van Osch, J H M van Bilsen, M J Knapen, A W M Evers, M T E Hopman, L A L M Kiemeney, S Wopereis, Niels H Chavannes, Jessica C Kiefte-de Jong, Jochen Mierau, Stef Kremers","doi":"10.1136/fmch-2025-003324","DOIUrl":"10.1136/fmch-2025-003324","url":null,"abstract":"<p><p>In recent years, significant insights have been gathered into the effectiveness of lifestyle interventions in the treatment of chronic non-communicable diseases (NCD). To speed up the implementation of evidence-based lifestyle medicine, we developed a research agenda in collaboration with Dutch experts in treating NCD, using a hybrid Delphi approach. The research agenda focuses on four key themes: (1) promoting sustainable behavioural change at patient, healthcare professional and organisational levels; (2) optimising research designs, methodology and outcomes for the evaluation of effectiveness and implementation of lifestyle medicine modalities in healthcare practice; (3) elucidating biological mechanisms underlying successful lifestyle interventions and (4) advancing data infrastructure to ensure accessible data for citizens, healthcare professionals, researchers and health insurers for monitoring and evaluation of health and lifestyle outcomes. Collectively, the identified knowledge questions across these four themes provide guidance for (applied) research towards lifestyle medicine in healthcare.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trial-based economic evaluations of non-drug interventions in the Royal Australian College of General Practitioners (RACGP) Handbook of Non-Drug Interventions in primary care: a systemic review. 澳大利亚皇家全科医师学院(RACGP)初级保健非药物干预手册中基于试验的非药物干预经济评估:系统回顾。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-08-31 DOI: 10.1136/fmch-2025-003312
Tiffany Atkins, Darryn Marks, Caroline Dowsett, Paul Glasziou, Loai Albarqouni
{"title":"Trial-based economic evaluations of non-drug interventions in the Royal Australian College of General Practitioners (RACGP) Handbook of Non-Drug Interventions in primary care: a systemic review.","authors":"Tiffany Atkins, Darryn Marks, Caroline Dowsett, Paul Glasziou, Loai Albarqouni","doi":"10.1136/fmch-2025-003312","DOIUrl":"10.1136/fmch-2025-003312","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review assessed trial-based economic evaluations to provide empirical evidence on the cost-effectiveness of non-drug interventions (NDIs) that are currently recommended within the Royal Australian College of General Practitioners Handbook of Non-Drug Interventions (HANDI).</p><p><strong>Methods: </strong>Medline, CINAHL and PsycINFO along with clinical trial registries (clinicaltrials.gov and WHO International Clinical Trials Registry Platform) were searched from inception to 1 July 2025. Randomised controlled trials (RCTs) that reported cost effectiveness for a prescribed non-drug intervention (NDI) from HANDI were included in the study. The primary outcome was the incremental cost-utility ratio (ICUR) derived from cost-utility analyses (CUAs).</p><p><strong>Results: </strong>A total of 11 187 citations were identified, from which 156 RCTs were included. These RCTs enrolled a total of 66 926 participants (median=214, IQR 139-342), with a median follow-up duration of 12 months (IQR 6-12 months). Over half of the CUA NDIs were for mental health conditions (n=81; 54.0%), one-third were for were for musculoskeletal conditions (n=44; 29.3%), while only 16.0% (n=24) were for those with cardiovascular/metabolic conditions. Out of the 150 NDIs that reported CUAs, 40% were deemed to be in the south-east (SE) quadrant (cheaper and more effective) and 49.3% fell in the north-east (NE) quadrant (more costly but more effective), with 70% considered cost effective against a £25 000/quality-adjusted life-year (QALY) willingness to pay threshold. The overall median ICUR was £2400/QALY (IQR -18 986 to 20 027).</p><p><strong>Conclusions: </strong>Most of the HANDI NDIs that were included within this systematic review are cost-effective compared with a variety of alternatives including usual care or waiting list controls. HANDI NDIs warrant use as a first line of treatment when clinically appropriate.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Follow-up of grieving families in general and family medicine: a cross-sectional study on the practices and attitudes of family doctors. 一般家庭医学对悲伤家庭的随访:家庭医生的做法和态度的横断面研究。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-08-24 DOI: 10.1136/fmch-2025-003296
Fábio Leite Costa, Miguel Barbosa
{"title":"Follow-up of grieving families in general and family medicine: a cross-sectional study on the practices and attitudes of family doctors.","authors":"Fábio Leite Costa, Miguel Barbosa","doi":"10.1136/fmch-2025-003296","DOIUrl":"10.1136/fmch-2025-003296","url":null,"abstract":"<p><strong>Introduction: </strong>Family physicians (FPs) provide essential support during life's most challenging moments, including experiences of grief and loss. After a patient's death, FPs are expected to provide information and emotional support to bereaved family members. Prior research suggests that bereaved relatives expect follow-up contact from their FP, acknowledging it as part of the physician's role. This study aims to explore the practices and attitudes of FPs towards bereaved family members.</p><p><strong>Methods: </strong>A cross-sectional, descriptive study was conducted through an online questionnaire, exploring participants' perceived role in bereavement care, the type of support offered to families, available resources in primary care, as well as personal knowledge and approach on grief. This questionnaire was distributed via digital platforms to general and family medicine doctors.</p><p><strong>Results: </strong>A total of 210 physicians participated (84.3% female; 53.8% in residency), with a median age of 32 years old. On average, each FP experienced five patient deaths, most often reported by family members. More than half (53.3%) contacted bereaved families in fewer than 25% of cases, typically within 7 days of the death, most commonly by phone (76.5%).</p><p><strong>Conclusion: </strong>This study highlights significant gaps in the bereavement follow-up practices of FPs in Portugal. Findings emphasise the need for integrated bereavement care guidelines in primary care, institutional policies and investment in targeted training programmes to enhance grief's approach. The reported lack of grief training reinforces the need to integrate grief education into medical curriculum and continuous professional development. Structural improvements, such as the implementation of automatic death notifications within the healthcare system, are also critical for enabling timely and effective support.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tobacco and other substance co-use among adolescents and young adults with cancer who use tobacco: prevalence and associations with nicotine dependence and depression. 吸烟的青少年和年轻癌症患者中烟草和其他物质的共同使用:患病率及其与尼古丁依赖和抑郁的关系。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-08-17 DOI: 10.1136/fmch-2025-003362
Elizabeth J Siembida, Brittney Greene, Eun Jeong Oh, Kara P Wiseman, Melissa Basile, Nehal P Vadhan, Michael A Diefenbach
{"title":"Tobacco and other substance co-use among adolescents and young adults with cancer who use tobacco: prevalence and associations with nicotine dependence and depression.","authors":"Elizabeth J Siembida, Brittney Greene, Eun Jeong Oh, Kara P Wiseman, Melissa Basile, Nehal P Vadhan, Michael A Diefenbach","doi":"10.1136/fmch-2025-003362","DOIUrl":"10.1136/fmch-2025-003362","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco and other substance co-use has not been examined in adolescent and young adult (AYA) cancer survivors. We compared the prevalence of past-month co-use of tobacco+cannabis, alcohol and illicit drugs between AYAs with and without a cancer history and considered associations between co-use and nicotine dependence in AYA cancer survivors who use tobacco, exploring if past-year major depression moderates this relationship.</p><p><strong>Methods: </strong>2015-2019 National Survey on Drug Use and Health data were used to analyse past-month co-use in 7793 AYAs (228 with cancer; 7565 without cancer). Weighted univariable and multivariable logistic regression models estimated associations between cancer history and co-use and co-use with nicotine dependence (among AYA cancer survivors) incorporating moderation by major depression.</p><p><strong>Results: </strong>AYA cancer survivors had lower reported past-month cannabis co-use than those without cancer (29% vs 39%), but cancer history was not associated with cannabis co-use in multivariable models (adjusted OR (aOR): 0.83, 95% CI=0.54, 1.28). When AYA cancer survivors who use tobacco had major depression, alcohol co-use was associated with lower rates of nicotine dependence (aOR=0.08, 95% CI=0.01, 0.53).</p><p><strong>Conclusions: </strong>There are high rates of substance co-use among AYAs who use tobacco, consistent across cancer history. Unlike previous research, alcohol co-use was associated with lower rates of nicotine dependence, but only for those with major depression. This finding could be related to neurochemical dysregulation due to co-use and warrants further exploration. Future research should also examine more nuanced definitions of substance use including modes, patterns and initiation of use, and explore motivation to change tobacco behaviour in AYA cancer survivor populations.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12359523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring treatment burden related to general practice in patients with multimorbidity: development and validation of a PROM. 测量与多病患者一般实践相关的治疗负担:PROM的开发和验证。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-08-17 DOI: 10.1136/fmch-2025-003378
Anna Bernhardt Lyhnebeck, Anne Holm, Sussi Friis Buhl, Kristine Henderson Bissenbakker, Jette Kolding Kristensen, Anne Møller, Anders Prior, Zaza Kamper-Jørgensen, Sidsel Böcher, Mads Kristensen, Asger Waagepetersen, Anders Hye Dalsgaard, Volkert Siersma, John Brandt Brodersen
{"title":"Measuring treatment burden related to general practice in patients with multimorbidity: development and validation of a PROM.","authors":"Anna Bernhardt Lyhnebeck, Anne Holm, Sussi Friis Buhl, Kristine Henderson Bissenbakker, Jette Kolding Kristensen, Anne Møller, Anders Prior, Zaza Kamper-Jørgensen, Sidsel Böcher, Mads Kristensen, Asger Waagepetersen, Anders Hye Dalsgaard, Volkert Siersma, John Brandt Brodersen","doi":"10.1136/fmch-2025-003378","DOIUrl":"10.1136/fmch-2025-003378","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to either identify or develop and validate a patient-reported outcome measure (PROM) to assess treatment burden related to general practice for patients with multimorbidity, which can be used alongside the MultiMorbidity Questionnaire part 1 (MMQ1) without overwhelming the target population with redundant items.</p><p><strong>Methods: </strong>We conducted a systematic literature review to identify all existing PROMs measuring treatment burden. If no suitable PROM was found, our plan was to: (1) develop a draft PROM using items from existing instruments, (2) carry out group and individual interviews with patients with multimorbidity to ensure the PROM's understandability, clarity, completeness and relevance and (3) undertake psychometric validation with a diverse sample of primary care patients with chronic conditions.</p><p><strong>Results: </strong>We did not identify an eligible PROM in the literature review. The draft PROM consisted of 30 items divided into six domains; Information about treatment, Challenges with medication, Medical appointments, Self-monitoring, Health behaviour and Challenges in the contact to the health system. In the psychometric validation, neither these domains nor any other theoretical constellation of items had adequate psychometric properties. Individual items had good criterion validity and sensitivity to change.</p><p><strong>Conclusions: </strong>In this study, we developed a 30-item PROM with high content validity where various individual items showed adequate criterion validity and sensitivity to change, making these items useful as a supplemental measure to the MMQ1.</p><p><strong>Trial registration number: </strong>NCT05676541 Registration Date: 16 December 2022.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12359414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Process for mainstreaming genetic cascade testing into primary and tertiary health systems in familial hypercholesterolaemia (FH), an autosomal dominant, fully penetrant disorder. 家族性高胆固醇血症(FH)是一种常染色体显性、完全渗透的疾病,将基因级联检测纳入初级和三级卫生系统的过程。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-08-14 DOI: 10.1136/fmch-2024-003258
Karen L Birkenhead, David Sullivan, Madeline Calder, Catherine Spinks, Gabrielle Fleming, Claire Trumble, Cameron Hemmert, Ronald Trent, Shubha Srinivasan, Kerrie Martin, Bridie Carr, Charlotte M Hespe, Mitchell Sarkies
{"title":"Process for mainstreaming genetic cascade testing into primary and tertiary health systems in familial hypercholesterolaemia (FH), an autosomal dominant, fully penetrant disorder.","authors":"Karen L Birkenhead, David Sullivan, Madeline Calder, Catherine Spinks, Gabrielle Fleming, Claire Trumble, Cameron Hemmert, Ronald Trent, Shubha Srinivasan, Kerrie Martin, Bridie Carr, Charlotte M Hespe, Mitchell Sarkies","doi":"10.1136/fmch-2024-003258","DOIUrl":"10.1136/fmch-2024-003258","url":null,"abstract":"<p><strong>Introduction: </strong>Advances in clinical genomics have raised the importance of integrating genomic medicine across healthcare systems, including primary care. Primary care presents an ideal environment to offer equitable and efficient access to genetic services. Familial hypercholesterolaemia (FH) is a preventable and treatable cause of premature heart disease and represents a health condition that can be successfully diagnosed and managed in primary care. This study describes a process for tailoring a primary-tertiary shared care model for FH to optimise health professional and patient engagement.</p><p><strong>Methods: </strong>Data were collected through semistructured interviews (n=10) with stakeholders in New South Wales, Australia. Interviews gathered feedback on how to tailor a shared care model for FH between tertiary and primary care services. Reflexive thematic analysis was used to analyse interview transcripts.</p><p><strong>Results: </strong>Analysis generated three main themes: (1) current process for genetic testing and management, (2) challenges with genetic testing for FH in primary care and (3) components needed to enable a tertiary-initiated shared care model. Participants considered the model of care acceptable and could be successfully implemented, provided key supports were in place to assist general practitioners. Based on these results, a process model for integrating genetic testing for other conditions into primary care settings was developed, using FH as an exemplar.</p><p><strong>Conclusion: </strong>The process model for tailoring of a primary-tertiary model of care for FH can be applied across a range of primary care services and treatable genetic conditions.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144856653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global evidence on the effectiveness of task-shifting and task-sharing strategies for managing individuals with multimorbidity: systematic review and meta-analysis. 关于任务转移和任务共享策略对管理多重疾病个体有效性的全球证据:系统回顾和荟萃分析。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-08-12 DOI: 10.1136/fmch-2025-003390
Enying Gong, Yutong Long, Xunliang Tong, Wai Yan Min Htike, Jiahui Wang, Shiqi Ni, Yueqing Wang, Zijun Wang, Lijing L Yan, Sumit Kane, Ruitai Shao, Yanming Li
{"title":"Global evidence on the effectiveness of task-shifting and task-sharing strategies for managing individuals with multimorbidity: systematic review and meta-analysis.","authors":"Enying Gong, Yutong Long, Xunliang Tong, Wai Yan Min Htike, Jiahui Wang, Shiqi Ni, Yueqing Wang, Zijun Wang, Lijing L Yan, Sumit Kane, Ruitai Shao, Yanming Li","doi":"10.1136/fmch-2025-003390","DOIUrl":"10.1136/fmch-2025-003390","url":null,"abstract":"<p><strong>Introduction: </strong>Task-shifting and task-sharing strategies show promise for managing chronic diseases especially in low-income and middle-income countries (LMICs), though their effectiveness in multimorbidity management remains unclear. This study synthesised evidence on task-shifting and task-sharing strategies globally and assessed the impact on core health outcomes in multimorbidity management.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis of global studies evaluating task-shifting and sharing interventions for individuals with multimorbidity. Six databases, including PubMed, Embase, Web of Science, Ovid (Medline), CINAHL and Cochrane Library, were searched for studies reporting the core outcomes of multimorbidity management in quality of life, mortality, hospitalisation, emergency department visits and symptoms of depression and anxiety. Random-effects models were used to calculate pooled effect sizes with heterogeneity assessed through subgroup and meta-regression analyses.</p><p><strong>Results: </strong>From 8471 records, 36 studies from 14 countries were included, with only 5 conducted in LMICs. Twenty-one studies, encompassing 20 989 participants, were eligible for meta-analysis. More than half of the studies involved nurses as delegates, with some sharing the tasks with health professionals and about 10% of studies involved non-health professionals, including community healthcare workers as delegates to share the responsibility in caring for individuals with multimorbidity. Most studies were multicomponent, with 16.7% addressing all guideline-recommended aspects of multimorbidity management. By pooling the findings, task-shifting and task-sharing interventions were associated with a 27% reduction in mortality (OR: 0.73, 95% CI: 0.55 to 0.97, I²=0%), a modest improvement in quality of life (standardised mean difference (SMD): 0.1, 95% CI: 0.03 to 0.17, I²=47%) and reduced symptoms of depression (SMD: 0.27, 95% CI: -0.52 to -0.02, I²=90%), but showed no significant effect on hospitalisation, emergency visits or anxiety-related symptoms.</p><p><strong>Conclusions: </strong>Some evidence, although limited in existing research, indicates the great potential of task-shifting and task-sharing strategies in supporting management of multimorbidity. Further research is needed to optimise and adopt these interventions, particularly in LMICs where evidence remains scarce.</p><p><strong>Prospero registration number: </strong>CRD42024526845.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acceptance and attitudes towards genetic cancer testing among German general practice patients: a cross-sectional survey. 接受和态度基因癌症测试在德国全科医生的病人:横断面调查。
IF 4.5 3区 医学
Family Medicine and Community Health Pub Date : 2025-07-31 DOI: 10.1136/fmch-2025-003395
Diana Guertler, Ann-Kristin Reinhard, Sabina Ulbricht, Jean-François Chenot, Ute Felbor, Susanne Wurm
{"title":"Acceptance and attitudes towards genetic cancer testing among German general practice patients: a cross-sectional survey.","authors":"Diana Guertler, Ann-Kristin Reinhard, Sabina Ulbricht, Jean-François Chenot, Ute Felbor, Susanne Wurm","doi":"10.1136/fmch-2025-003395","DOIUrl":"10.1136/fmch-2025-003395","url":null,"abstract":"<p><strong>Objective: </strong>This study describes acceptance and attitudes towards genetic cancer testing among German primary care patients.</p><p><strong>Design: </strong>Cross-sectional survey.</p><p><strong>Setting: </strong>Primary care.</p><p><strong>Participant: </strong>Systematically recruited patients aged ≥18 years from six general practices in Mecklenburg-Western Pomerania participated in an anonymous self-administered survey on familial cancer prevention (n=479 and 67.0% participation rate). Those with complete data were analysed (n=424; mean age 53.7, SD 16.6 years; men 34.4%). Linear regression analyses were used to examine potential disparities in general acceptance of genetic testing and attitudes towards genetic cancer testing according to sociodemographics and familial cancer knowledge.</p><p><strong>Result: </strong>General acceptance of genetic testing was high, particularly among younger, higher-educated individuals and those with a family history of cancer and higher familial cancer knowledge. For example, 83.3% either agreed or strongly agreed that it should be available to anybody. The most important benefits of genetic cancer testing were to guide check-up frequency (81.4%), to inform medical decision-making (80.2%) and to understand children's risk (75.2%). The most important concerns included the potential burden on the family (44.6%) and the belief that cancer cannot be prevented (39.2%). More favourable attitudes were found among younger, higher-educated individuals, those with a personal history of cancer and those with fewer children or no partner. For example, higher age was linked to lower benefit (regression coefficient (RC) -0.01, 95% CI -0.01 to -0.001) and higher concern ratings (RC 0.01, 95% CI 0.002 to 0.01). About a third (34.7%) rated not wanting to know about genetic alterations that increase their cancer risk as a (very) important reason against testing. Information avoidance was higher among older individuals (RC 0.02, 95% CI 0.01 to 0.02), women (RC 0.40, 95% CI 0.11 to 0.69), those with lower education (RC -0.64, 95% CI -0.91 to -0.36) and those with more children (RC 0.21, 95% CI 0.09 to 0.33).</p><p><strong>Conclusion: </strong>Acceptance of genetic testing was high, but barriers remain, particularly among older adults, women, the less educated and those with more children. Targeted educational efforts to improve health literacy, emphasise the preventive potential of genetic testing and emotional support through genetic counselling are essential to overcome these barriers and promote informed decision-making.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenge of long-term benzodiazepine use in primary care: insights from a real-world cohort study in Catalonia. 长期苯二氮卓类药物在初级保健使用的挑战:来自加泰罗尼亚现实世界队列研究的见解。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-07-31 DOI: 10.1136/fmch-2024-003233
María Teresa Peñarrubia-María, Lucy Anne Parker, Marta Puig-García, Marina Fuente-Moreno, Blanca Lumbreras, Elsa Lopez-Pintor, Joan Domenech Abella, Marc Saez, Alexandra Lelia Dima, Adolfo Figueiras Guzmán, Elisa Chilet Rosell, Antoni Serrano-Blanco, Ignacio Aznar-Lou
{"title":"Challenge of long-term benzodiazepine use in primary care: insights from a real-world cohort study in Catalonia.","authors":"María Teresa Peñarrubia-María, Lucy Anne Parker, Marta Puig-García, Marina Fuente-Moreno, Blanca Lumbreras, Elsa Lopez-Pintor, Joan Domenech Abella, Marc Saez, Alexandra Lelia Dima, Adolfo Figueiras Guzmán, Elisa Chilet Rosell, Antoni Serrano-Blanco, Ignacio Aznar-Lou","doi":"10.1136/fmch-2024-003233","DOIUrl":"10.1136/fmch-2024-003233","url":null,"abstract":"<p><strong>Introduction: </strong>Long-term use of benzodiazepines (BZD) triggers health problems. Although Spain leads European use of BZD, the number of long-term users (LTUs) remains unknown.</p><p><strong>Objective: </strong>The aim of the study is to estimate the proportion of primary care (PC) patients who initiate a BDZ prescription that subsequently become LTU and to identify its associated factors.</p><p><strong>Design: </strong>Retrospective real-world data cohort.</p><p><strong>Setting and participant: </strong>It included the population over 15 years with a new prescription of BZD in PC in Catalonia. Users were considered LTU if they had been dispensed at least three prescriptions within 3 months. Sociodemographic characteristics of patients and prescribers, pathologies, previous BZD use, number and type of visits, and prescription quality standard were considered. We estimated the proportion of LTU among patients with a new prescription, stratified by age and sex, and estimated risk factors by multivariate generalised linear models.</p><p><strong>Result: </strong>100 638 users with a new BZD prescription were included. 27.1% were LTU at 3 months and 14.5% at 6 months. LTU increases with age and is higher in women. Predictors of LTU are Spanish nationality, living in rural areas, having a mental illness, having used BZD, having virtual visits or not meeting pharmacy-therapeutic quality standards.</p><p><strong>Conclusion: </strong>The number of patients who develop LTU is high, especially in the elderly. Exploring the causes of this phenomenon could contribute to the development of future interventions.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Educational and research utility of the registrar clinical encounters in training (ReCEnT) project: an exploration of mechanisms using the context, input, process and product (CIPP) framework. 注册医师临床经验培训(近期)项目的教育和研究效用:利用情境、投入、过程和产品(CIPP)框架探索机制。
IF 4.3 3区 医学
Family Medicine and Community Health Pub Date : 2025-07-21 DOI: 10.1136/fmch-2025-003289
Michael Tran, Susan Wearne, Andrew Davey, Parker Magin
{"title":"Educational and research utility of the registrar clinical encounters in training (ReCEnT) project: an exploration of mechanisms using the context, input, process and product (CIPP) framework.","authors":"Michael Tran, Susan Wearne, Andrew Davey, Parker Magin","doi":"10.1136/fmch-2025-003289","DOIUrl":"10.1136/fmch-2025-003289","url":null,"abstract":"<p><strong>Background: </strong>The Registrar Clinical Encounters in Training (ReCEnT) project is an Australian general practice vocational training programme with integrated and interdependent education and research functions. Trainees (registrars) contemporaneously document in-consultation clinical experience and actions.</p><p><strong>Objectives: </strong>Using a realist lens, we elucidate the mechanisms underpinning project outcomes to answer questions around programme effectiveness, impacts, sustainability and the lessons and findings that are translatable to other primary care training programmes.</p><p><strong>Methods: </strong>The context, input, process and product framework was used. As a means to understand the interactions between each of the interdependent components, it allows for inferences regarding causal mechanisms for specific outcomes.</p><p><strong>Results: </strong>Context: ReCEnT occurs within an apprenticeship-like model of general practice vocational training entailing a central supervisor/apprentice relationship. ReCEnT has demystified the content and characteristics of registrar consultations. Input: multiple stakeholder involvement is both advantageous and a logistical challenge, with the programme's success dependent on registrars, practices and training providers providing detailed and accurate data, with prompt subsequent processing.</p><p><strong>Process: </strong>contemporaneous consultation data collection in different stages of training constitutes a component of registrars' programmatic assessment. Product: individualised feedback provides educational benefit through reflection. Clinical and educational research questions can be addressed with resulting research translation feeding back into the programme model and government policy. Clinical behaviour change is also evaluated.</p><p><strong>Conclusion: </strong>ReCEnT is unique, globally, in its scope and longevity (2010-present). Creation of meaningful, individualised feedback facilitates reflection and provides both immediate educational benefits and the substrate for further research, programme and policy design and targeted formal teaching and learning.</p>","PeriodicalId":44590,"journal":{"name":"Family Medicine and Community Health","volume":"13 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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