Tobacco Prevention & Cessation最新文献

{"title":"Prevalence, perceived effects, and motivations for adolescent e-cigarette use: A cross-sectional study in the Paris region.","authors":"Mathilde Gendrot, Anne-Laurence Le Faou","doi":"10.18332/tpc/225318","DOIUrl":"10.18332/tpc/225318","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescence is a critical period for experimentation with psychoactive substances, including electronic cigarettes (e-cigarettes). This study aimed to assess the prevalence of e-cigarette use among high school students in Paris and to explore adolescents' motivations for use and their perceptions of its effects.</p><p><strong>Methods: </strong>This cross-sectional study, based on self-reported data collected through an online questionnaire, was conducted between January and April 2021 among students from six educational institutions in the Paris region. The anonymized survey collected demographic and health data, information on tobacco and e-cigarette use behaviors, and perceptions and motivations related to e-cigarette use. Associations between the social environment and tobacco and e-cigarette experimentation were evaluated using prevalence ratios, crude odds ratios (ORs), and adjusted ORs (AORs), with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>A total of 1187 students participated (median age: 17 years; 55.5% male). E-cigarette experimentation was reported by 46.8%, current use by 18.9%, and daily use by 8.6%. The mean age at e-cigarette initiation was 14.9±1.9 years. Dual experimentation with tobacco and e-cigarettes was observed in 39.2% of participants, while 5.2% reported exclusive e-cigarette use. Curiosity was the most frequently reported motivation for e-cigarette ever users (91.4%), followed by flavor variety (75.0%), and the ability to use e-cigarettes at home without tobacco odor (63.6%). Exposure to e-cigarette use among friends was strongly associated with e-cigarette experimentation (AOR=3.68; 95% CI: 2.88-4.73). Notably, 23.4% of all respondents and 12.3% of e-cigarette ever users were unaware whether e-liquids contained nicotine. Most e-cigarette users expressed concerns about lung health (85.2%) and addiction risk (75.5%).</p><p><strong>Conclusions: </strong>E-cigarette use is prevalent among adolescents in the Paris region and is driven by curiosity, sensory appeal, and social influences. Additional studies, particularly longitudinal cohort studies, are needed to provide evidence-based information on tobacco and e-cigarette use trajectories among adolescents.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and facilitators to delivering tobacco cessation interventions at HIV care clinics in Sub-Saharan Africa: Qualitative application of the consolidated framework for implementation research.","authors":"Kyra Guy, Jennifer Tsui, Ezekiel Musasizi, Ronald Kusolo, Musawa Mukupa, Jim Arinaitwe, Fastone Goma, Lynn Atuyambe, David Guwatudde, Masauso M Phiri, Cosmas Zyambo, Heather Wipfli","doi":"10.18332/tpc/221806","DOIUrl":"10.18332/tpc/221806","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco use among people living with HIV (PLWH) in Sub-Saharan Africa (SSA) is prevalent, compounding health risks. Tobacco cessation interventions (TCIs) have shown promise but are not widely tested in HIV care settings. In this study, we applied the Consolidated Framework for Implementation Research (CFIR) to examine barriers and facilitators to implementing the adapted tobacco cessation intervention Quit4life+ for PLWH in Uganda and Zambia.</p><p><strong>Methods: </strong>Guided by the CFIR determinant framework, Quit4life+ trial implementation challenges were evaluated across 16 HIV clinics in Uganda and Zambia between July 2021 and October 2025. Qualitative data were drawn from multiple sources, including 22 quarterly site visit reports, 4 health systems assessments completed by study coordinators and health facility personnel in-charge, key informant interviews with 14 clinic healthcare providers (nurses, nursing officers, and midwives), and focus group discussions with 55 PLWH (aged ≥18 years and receiving HIV care at participating clinics). Qualitative data were mapped to relevant domains and constructs.</p><p><strong>Results: </strong>Within the innovation domain, evidence for TCIs, nicotine replacement therapy (NRT), and culturally adapted message libraries enhanced acceptability, while costs challenged adoption. Outer setting challenges, including seasonal labor demands, civil unrest, poor road access, and restrictive procurement and regulatory processes, influenced delivery. Inner setting barriers included overcrowded clinics, limited counseling space, inconsistent network connectivity, and staff turnover. Providers were motivated to support cessation but reported limited skills and faced intersecting stigma among patients. The implementation process relied on external resources, raising concerns about sustainability.</p><p><strong>Conclusions: </strong>Findings identify multilevel barriers and facilitators to delivering cessation support within HIV care clinics in Uganda and Zambia. Further research is needed to determine how determinants can be effectively addressed and to build the evidence base for the sustainable integration of services into HIV care across SSA.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13422703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148632228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"School administrator perspectives on electronic nicotine delivery systems use in Montana schools: A mixed-methods study.","authors":"Suzanna Powell, Steven Fuller, Tara Spence, Lisa Richidt, Nicole Aune","doi":"10.18332/tpc/224416","DOIUrl":"10.18332/tpc/224416","url":null,"abstract":"<p><strong>Introduction: </strong>Schools have become central to addressing the prevention, detection, and cessation of youth's use of Electronic Nicotine Delivery Systems (ENDS). This study surveys and interviews school administrators in Montana to identify effective prevention, discipline, and cessation strategies in schools.</p><p><strong>Methods: </strong>A mixed-methods study was conducted from March through September 2025, including an online survey with 42 responses from school administrators and 11 follow-up interviews. All Montana school districts (n=400) were invited to participate in the survey, and interview participants were recruited from survey respondents. Survey questions ranged from perceptions of ENDS use to the perception and effectiveness of prevention, discipline, and cessation strategies. Interviews expanded on key survey findings and captured insights into school-level experiences related to ENDS use, prevention, discipline, and cessation strategies.</p><p><strong>Results: </strong>Of the 400 school districts sent the survey, a response rate of 10.5% (n=42) was achieved. Just over half (61%, n=25) observed student ENDS use on school grounds during the 2024-2025 school year. Certain measures, like implementing student education sessions (90%, n=36) and hallway/bathroom patrols to prevent use and notifying parents for a first offense (95%, n=38) were seen as moderately or very effective. Cessation efforts were more varied, and respondents expressed a desire for more options. The least expensive measures, such as educational sessions, installing tobacco-free signs, and putting up educational posters, were the most commonly implemented measures. In the end, interviews emphasized the need for working collaboratively with peers, parents, and school resource officers to increase prevention, cessation, and disciplinary effectiveness.</p><p><strong>Conclusions: </strong>Prevention, cessation, and disciplinary strategies to reduce ENDS use at schools vary greatly across Montana. However, respondents consistently expressed a desire for more disciplinary options and cessation resources, and noted that involving peers, parents, and school resource officers in prevention, cessation, and disciplinary strategies increased perceived effectiveness.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaping cessation interventions: A narrative review of randomized controlled trials.","authors":"Tetiana Zolotarova, Areesha Moiz, Audrey Lelièvre, Mark J Eisenberg","doi":"10.18332/tpc/222678","DOIUrl":"10.18332/tpc/222678","url":null,"abstract":"<p><p>The increasing prevalence of electronic cigarette (e-cigarette) use, particularly among young individuals, has led to a pressing need for effective vaping cessation interventions. We conducted a narrative review of published and ongoing randomized controlled trials (RCTs) evaluating behavioral, pharmacological, and combination interventions aimed at vaping cessation among adolescents and adults using e-cigarettes. PubMed, Google Scholar, and ClinicalTrials.gov were searched from 2004 (year of first e-cigarette patent) to 27 April 2025. The outcome of interest was abstinence from vaping at the maximum follow-up and results were synthesized narratively. A total of 11 RCTs, involving 8182 participants, were identified. These trials investigated behavioral therapy, including tailored text messaging support (n=4), nicotine replacement therapy (NRT) (n=3), varenicline (n=3), and cytisine (n=1). Studies were published between 2021 and 2025, with follow-up ranging from 1 to 24 months, and most focused on adults or young adults. Behavioral interventions, particularly text messaging programs, showed potential to support vaping cessation beyond 6 months, although findings were inconsistent across trials. Varenicline demonstrated promise as a pharmacological aid; however, available RCTs had small sample sizes and short follow-up periods, limiting the strength of the evidence. None of the RCTs investigating the efficacy of NRT (567 participants) or cytisine (160 participants) demonstrated superiority over control following treatment discontinuation. Fourteen ongoing RCTs were also identified, most of which are evaluating behavioral approaches in younger populations. Overall, the current evidence base for vaping cessation remains limited, highlighting the need for larger, high-quality trials with longer follow-up to establish effective interventions across diverse populations.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity of the Fagerström test for nicotine dependence among persons with intellectual disabilities: Cross-sectional evidence from the POWER PID study.","authors":"Christian Ben Lakhdar, Sophie Massin, Morgane Le Blanc, Agnès d'Arripe, Cédric Routier","doi":"10.18332/tpc/221010","DOIUrl":"10.18332/tpc/221010","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco use and the screening of nicotine dependence using the Fagerström test among adults with intellectual disabilities (ID) is an understudied public health issue. Despite lower reported prevalence relative to the general population, methodological challenges - particularly the suitability of self-reported tools - limit reliable measurement. This study assesses the convergent validity of the Fagerström test for nicotine dependence (FTND) by comparing it with exhaled carbon monoxide (CO), an objective biomarker of recent smoking, in a sample of adults with ID.</p><p><strong>Methods: </strong>Data were collected from an observational cross-sectional validation study during 2024, which investigates addictive behaviors, health indicators, and physical activity among adults with ID in northern France. Nurses administered a standardized questionnaire, including the FTND, and measured exhaled CO using a portable analyzer. Associations were examined using correlation analyses and univariable and multivariable linear regressions controlling for sociodemographic and health variables.</p><p><strong>Results: </strong>Among 35 people who smoke, FTND scores were positively and strongly correlated with exhaled CO (r=0.540, p<0.001). In adjusted regression models, FTND remained a significantly associated factor of CO levels (0.60; 95% CI: 0.17-1.02), alongside age (0.065; 95% CI: 0.00-0.13), employment in sheltered workshops (1.86; 95% CI: -0.07-3.78), and cognitive support needs (-1.62; 95% CI: -3.51-0.26). Analyses conducted on the full sample, including 68 people who do not smoke, yielded consistent results, with FTND remaining the strongest predictor of exhaled CO.</p><p><strong>Conclusions: </strong>The results suggest evidence of validity of the FTND in adults with ID, suggesting that self-report instruments can reliably estimate nicotine dependence when administered with appropriate support. Nevertheless, the interpretation of CO levels in adults with ID should account for age, cognitive support needs, and contextual factors.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13389871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional study of predictors of perceptions of addiction among college students using Electronic Nicotine Delivery System users.","authors":"Eliza Coull, Madison Fanus, Olivia LiCausi, Sharon Kingston","doi":"10.18332/tpc/219091","DOIUrl":"10.18332/tpc/219091","url":null,"abstract":"<p><strong>Introduction: </strong>It is estimated that almost one quarter of young adults use electronic nicotine delivery systems (ENDS) despite health risks. Perceptions of addiction to nicotine has been linked with motivation to quit, highlighting the importance of understanding contributors to addiction perceptions among young adults.</p><p><strong>Methods: </strong>The current study used cross-sectional survey data to examine how perceptions of addiction were impacted by physical dependence, risk perception, intention to quit, number of quit attempts, and initiation regret among a sample of undergraduate students (n=99) who had used ENDS within the past 30 days. Participants were aged 18-23 years with a mean age of 19.64 years (SD=1.156). The majority (64.6%) identified as women, and 61.6% identified as White.</p><p><strong>Results: </strong>Only symptoms of nicotine dependence were significantly related to perception of addiction (β=-0.636; 95% CI: -0.829--0.474, t=-7.415, p<0.001) indicating that experiencing more symptoms of nicotine dependence predicted stronger perceptions of nicotine addiction. The number of lifetime quit attempts moderated the relationship between symptoms of addiction and perception of addiction (β=0.129; 95% CI: 0.069-0.190, p<0.000) such that symptoms of nicotine dependence have a stronger relationship with perceptions of addiction when an individual has engaged in fewer quit attempts. The number of quit attempts did not moderate the relationship between initiation regret and perceptions of addiction or the relationship between perceptions of the risk of becoming addicted to vaping and perceptions of addiction.</p><p><strong>Conclusions: </strong>The results highlight the role of symptoms of physical dependence on perceptions of addiction among young adults attending college. Surprisingly, this relationship was stronger for individuals with fewer quit attempts. Perhaps more failed quit attempts lead young adults to adopt self-exemption beliefs and disconnect their symptoms of nicotine dependence from their perception that they are addicted to ENDS.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waterpipe use among people who smoke in rural Vietnam: Secondary analysis from the M2Q2 randomized clinical trial.","authors":"Andrew W Liu, Yvonne P Nguyen, Narayani Ballambat, Hai Tran, Xuan Nguyen, Julie Flahive, Jeroan J Allison, Nguyen Vu, Hoa L Nguyen, Rajani S Sadasivam","doi":"10.18332/tpc/217702","DOIUrl":"10.18332/tpc/217702","url":null,"abstract":"<p><strong>Introduction: </strong>Waterpipe (WTP) tobacco smoking is highly prevalent in Vietnam. WTP use is associated with higher nicotine exposure and increased risk of pulmonary and cardiovascular diseases. The aim of this study is to understand WTP use and how it may influence smoking behaviors and cessation.</p><p><strong>Methods: </strong>We conducted a secondary analysis of data from the mHealth Messaging to Motivate Quitline Use and Quitting (M2Q2) randomized trial, which evaluated a mobile health peer-texting intervention in Northern Vietnam. Logistic and mixed-effects logistic regression was used to assess the association between WTP, CO-verified cessation, and Quitline use, after accounting for commune-level clustering and adjusting for demographic factors and randomization.</p><p><strong>Results: </strong>Among 749 male smokers (mean age: 42.7 years), 53% reported WTP use. Higher education (high school: adjusted odds ratio, AOR=0.61; CI: 0.43-0.86, college: AOR=0.47; CI: 0.30 - 0.73), and age >60 years (AOR=0.53; CI: 0.28-0.99) were inversely associated with WTP use, compared to smokers who only completed secondary school, and were aged <30 years, respectively. Compared to non-WTP users, WTP users smoked fewer cigarettes daily (p<0.001), smoked sooner after waking (p<0.001), spent more money weekly on tobacco products (p<0.001), and began smoking at an earlier age (p=0.02). WTP was not significantly associated with CO-verified cessation, and users had lower non-significant Quitline use.</p><p><strong>Conclusions: </strong>WTP users differed from non-WTP users in demographic and smoking behaviors. WTP did not significantly affect CO-verified cessation, with a non-significant trend of reduced Quitline use, suggesting barriers to treatment uptake. Tailored cessation strategies that address WTP-specific challenges are needed to improve outcomes in this high-risk group.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic characteristics, tobacco use, and service utilization by county poverty status among Oklahoma tobacco helpline registrants: A cross<b>-</b>sectional study.","authors":"Gaurav Kumar, Laura A Beebe, Motolani E Ogunsanya, Mark P Doescher, Ryan Nipp, Nirmal Choradia, Laili K Boozary, Nathalia M Machado, Darla E Kendzor","doi":"10.18332/tpc/218374","DOIUrl":"10.18332/tpc/218374","url":null,"abstract":"<p><strong>Introduction: </strong>Residents of counties with higher poverty levels experience elevated smoking rates and disproportionate tobacco-related cancer mortality. This study examined differences in sociodemographic characteristics, tobacco use, and service utilization among Oklahoma Tobacco Helpline (OTH) registrants across county poverty designations.</p><p><strong>Methods: </strong>In this cross-sectional study, data were analyzed from 33847 adults registered with the OTH between 1 July 2023 and 30 June 2024. Counties were classified as persistent poverty (PPC: ≥20% of residents in poverty for ≥30 years), current poverty (CPC: ≥20% of residents in poverty currently for <30 years), or non-poverty (NPC: <20% of residents in poverty). Group differences were examined using the chi-squared test and analysis of variance. Adjusted multinomial logistic regression analyses evaluated associations between poverty status, tobacco use, and service utilization, controlling for age, sex/gender, race, education level, household income, health insurance, and chronic conditions.</p><p><strong>Results: </strong>Registrants residing in PPCs and CPCs differed from those in NPCs in terms of age and race, and they had lower education, income, and greater Medicaid coverage (all P<0.05). In adjusted models, PPC registrants had higher odds of smoking >1 pack/day (heavy smoking) (AOR=1.49; 95% CI: 1.30-1.70; p<0.001) and learning about OTH through personal networks (AOR=1.42; 95% CI: 1.16-1.73; p<0.001) compared with NPCs. Compared with registrants residing in non-poverty counties (NPCs), CPC registrants had higher odds of smoking >1 pack/day (AOR=1.39; 95% CI: 1.16-1.65; p<0.001) and learning about OTH through community/social organizations (AOR=1.77; 95% CI: 1.33-2.35; p<0.001). Service type and nicotine replacement therapy receipt/duration were similar across poverty designations.</p><p><strong>Conclusions: </strong>PPC and CPC registrants showed greater socioeconomic disadvantage and nicotine dependence than NPC registrants but had distinct information pathways. These findings highlight geographically concentrated poverty as a potential contributor to tobacco-related disparities and suggest that interventions addressing social and environmental conditions in PPCs may help enhance cessation engagement and reduce tobacco-related inequities.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing reasons for e-cigarette use among Filipino adults who smoke: A cross-sectional study.","authors":"Raniyan Zaman, Lauren Czaplicki, Elizabeth Crespi, Joanna E Cohen, E Ulysses Dorotheo, Madeleine Valera, Ana Mayor, Filomena T Dayagbil, Kevin Welding","doi":"10.18332/tpc/221661","DOIUrl":"10.18332/tpc/221661","url":null,"abstract":"<p><strong>Introduction: </strong>There is a potential risk of increased dual use of e-cigarettes and cigarettes among people who currently smoke and use e-cigarettes. Limited data are available on why people who smoke in the Philippines use e-cigarettes, including reasons that relate to smoking cessation. The current study addresses this gap to inform e-cigarette regulatory strategy.</p><p><strong>Methods: </strong>Data were collected via an online self-administered cross-sectional survey in November 2023 from 611 Filipino adults who smoke and reported current e-cigarette use (i.e. dual users). Participants selected their primary reason for e-cigarette use from a pre-populated list of 15 reasons. We conducted separate logistic regression models of each top reason for e-cigarette use, controlling for demographic and tobacco-use variables.</p><p><strong>Results: </strong>The top primary reasons for e-cigarette use were to cut down smoking (26%), to help quit smoking (24%), to use when not allowed to smoke cigarettes (11.6%), vaping is less harmful than smoking to others around me (11.6%), and 'I enjoy the flavor' (8.5%). Men were more likely than women to select to help quit (adjusted odds ratio, AOR=1.84; p=0.003, 95% CI: 1.22-2.77). Those intending to quit smoking within the year were more likely to select to help quit (AOR=5.22; p<0.001, 95% CI: 2.30-11.9) and to cut down (AOR=2.84, p<0.001, 95% CI: 1.36-5.95), and less likely to select to use when not allowed to smoke (AOR=0.25, p<0.001, 95% CI: 0.13-0.50) and because 'I enjoy the flavor' (AOR=0.24, p<0.001, 95% CI: 0.12-0.49).</p><p><strong>Conclusions: </strong>Some people who smoke in the Philippines use e-cigarettes in order to support smoking cessation; however, there is a risk of prolonged dual use if strong regulations are not implemented to promote complete cessation. Further research should investigate causal factors for e-cigarette use to identify policy pathways for reducing dual use and supporting cessation efforts.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of biochemical markers as adjuncts to the Fagerström test in evaluating nicotine dependence: A retrospective observational study.","authors":"Laura Gil-Pintor, Enrique Barrueco Otero, Vanesa Hidalgo-Sierra, Rosa Cordovilla Pérez, Miguel Ángel Hernández-Mezquita","doi":"10.18332/tpc/216111","DOIUrl":"10.18332/tpc/216111","url":null,"abstract":"<p><strong>Introduction: </strong>Nicotine dependence assessment is essential in smoking cessation programs. The Fagerström test for nicotine dependence (FTND) is widely used, but its subjective nature limits its accuracy. Biomarkers, such as cotinine, exhaled carbon monoxide (CO), and carboxyhemoglobin (COHb), provide objective measures of tobacco exposure and complement information for disease management. This study aimed to evaluate the association between biochemical markers and nicotine dependence measured by FTND in a large population of smokers attending a smoking cessation program, and to determine which biomarkers best reflect dependence levels.</p><p><strong>Methods: </strong>This retrospective observational study was conducted in the Health Area of Salamanca, including the Smoking Cessation Unit of Salamanca University Hospital and all Primary Care centers in the metropolitan area, from January 2009 to July 2021. A total of 3820 smokers were included. Demographic data, smoking history, and nicotine dependence levels were recorded in patients' medical history at the first visit to the Smoking Cessation Unit. Biomarkers, including serum cotinine, exhaled CO, and COHb, were measured, and the association between these biomarkers and baseline FTND scores was analyzed. Although patients were followed for at least six months as part of a broader smoking cessation program, follow-up data were not included in the analysis.</p><p><strong>Results: </strong>Cotinine levels showed the strongest correlation with FTND (r=0.302, p<0.001), followed by COHb (r=0.234, p<0.001) and CO (r=0.219, p<0.001). When stratified by dependence level, mean concentrations of cotinine, CO, and COHb increased progressively from low to high dependence categories, with statistically significant differences across all groups (p<0.001).</p><p><strong>Conclusions: </strong>Biomarkers showed consistent associations with nicotine dependence measured by the FTND, with cotinine demonstrating the strongest association. Further studies are needed to confirm these findings and to provide sufficient evidence on the utility of biochemical markers in assessing nicotine dependence.</p>","PeriodicalId":44546,"journal":{"name":"Tobacco Prevention & Cessation","volume":"12 ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}