Sumer 1Pub Date : 2023-08-15DOI: 10.21931/rb/css/s2023.08.01.3
Alaa S. Kathim, Murtadha F. AL-Hillo
{"title":"Biochemical Changes of Dexamethasone on Liver and Kidney Functions in\u0000Laboratory Mice Mus musculus L.","authors":"Alaa S. Kathim, Murtadha F. AL-Hillo","doi":"10.21931/rb/css/s2023.08.01.3","DOIUrl":"https://doi.org/10.21931/rb/css/s2023.08.01.3","url":null,"abstract":"Background: The present study sought to verify the effect of dexamethasone on the biochemical changes in different organs, such as liver and kidney organs of both sexes, male\u0000and female mice. Materials & Method: Muc muscular males and female mice (n=48) were\u0000used. To determine the effects of dexamethasone on the biochemical changes of liver and\u0000kidney organs, mice received a low dose (2mg/kg) and a high dose (4 mg/kg) of dexamethasone continuously for one month. Result: The results showed a significant increase\u0000(P<0.05) in Liver enzymes (ALP, AST, ALT). The urea and creatinine levels also increased in the treated mice and both sexes with the pesticide compared with the control\u0000group.\u0000Keywords: mice, histological, liver, kidney, dexamethasone, toxicity","PeriodicalId":443152,"journal":{"name":"Sumer 1","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133379536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}