Turkish Archives of Otorhinolaryngology最新文献

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Protective and Therapeutic Effect of Platelet-Rich Plasma on Experimental Cisplatin Ototoxicity. 富血小板血浆对实验性顺铂耳毒性的保护和治疗作用。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-06-01 Epub Date: 2023-09-18 DOI: 10.4274/tao.2023.2022-7-9
Bahadır Gözaydın, Asude Ünal, Doğukan Özdemir, Ayşe Çeçen, Mustafa Bakırtaş
{"title":"Protective and Therapeutic Effect of Platelet-Rich Plasma on Experimental Cisplatin Ototoxicity.","authors":"Bahadır Gözaydın,&nbsp;Asude Ünal,&nbsp;Doğukan Özdemir,&nbsp;Ayşe Çeçen,&nbsp;Mustafa Bakırtaş","doi":"10.4274/tao.2023.2022-7-9","DOIUrl":"https://doi.org/10.4274/tao.2023.2022-7-9","url":null,"abstract":"<p><strong>Objective: </strong>Cisplatin is a chemotherapeutic agent with an ototoxic effect that is frequently used in head and neck cancers. There are studies in the literature conducted with various antioxidant substances to protect and/or prevent ototoxicity. This study aims to investigate whether platelet-rich plasma (PRP) has a protective and therapeutic effect on cisplatin ototoxicity.</p><p><strong>Methods: </strong>A total of 40 Sprague Dawley albino rats were divided into six groups as control group (n=6), PRP-only group (n=6), cisplatin group (n=6), cisplatin + PRP group (n=6), PRP + cisplatin group (n=6), and donor group (n=10). At the beginning of the study and the 8<sup>th</sup> day, they were tested with distortion product otoacoustic emission (DPOAE). Assessment of DPOAE results was based on the signal-to-noise ratio in 2000, 3000, 4000, 6000, and 8000 Hz frequency bands. On the 8<sup>th</sup> day, the rats were sacrificed. For histological examinations, the temporal bones were dissected and fixed. After hematoxylin and eosin staining, the tissues were evaluated by light microscopy.</p><p><strong>Results: </strong>In the DPOAE tests performed on the 0<sup>th</sup> and 8<sup>th</sup> days of the cisplatin group, it was observed that cisplatin caused hearing loss in the rat ears. It was determined that the cisplatin group at 2000 Hz, 3000 Hz and 4000 Hz had a significant decrease in hearing compared to all groups (p<0.015), while the cisplatin group at 6000 and 8000 Hz was characterized by hearing loss at a higher rate than all groups (p<0.001). At the end of the study, negative effects of cisplatin on both cellular dimensions (cytoplasmic vacuolization, cell degeneration, dilatation, apoptotic cells, nerve degeneration) and hearing function were observed. No protective or therapeutic effect of PRP on cisplatin ototoxicity was observed.</p><p><strong>Conclusion: </strong>Our study showed that platelet-rich plasma did not have a significant effect in the treatment of hearing loss due to cisplatin ototoxicity and in preventing hearing loss in rats.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 2","pages":"75-82"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/b2/tao-61-75.PMC10506523.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Factors Affecting Hearing Aid Use in Children. 儿童助听器使用影响因素的评价。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2022.2022-6-9
Nurşah Özal, Merve Özbal Batuk, Selen Yılmaz Işıkhan
{"title":"Evaluation of Factors Affecting Hearing Aid Use in Children.","authors":"Nurşah Özal,&nbsp;Merve Özbal Batuk,&nbsp;Selen Yılmaz Işıkhan","doi":"10.4274/tao.2022.2022-6-9","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-6-9","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to determine the factors affecting hearing aid use in children and investigate how these factors affected their subjective auditory performance.</p><p><strong>Methods: </strong>The study was carried out with 34 children aged three to six years who had mild or moderate sensorineural hearing loss and had used a bilateral hearing aid for at least six months. The daily hearing aid usage times of children were collected with the help of data logging software. Parent-child interactions were assessed with the Maternal Behavior Rating Scale (MBRS) and Child Behavior Rating Scale (CBRS) scores. To assess the parents' levels of knowledge about hearing devices, the Hearing Aid Awareness Question Form for Parents, which was prepared by the researchers, was used. Finally, to evaluate the subjective hearing performance of the children, the Parents' Evaluation of Aural/Oral Performance of Children (PEACH) survey was implemented.</p><p><strong>Results: </strong>Strong and significant correlations were found between the MBRS and CBRS scores, the results obtained from some questions in the Hearing Aid Awareness Question Form for Parents, the overall PEACH score, the QUIET subscale score, and the NOISE subscale score (p<0.001). According to the multivariate linear regression analyses, it was observed that the use of the pediatric clip hearing aids holder (question 17) had a significant effect in decreasing both the overall PEACH score (β=-3.07, p=0.008) and the PEACH-NOISE subscale score (β=-1.88, p=0.012). A unit increase in the score given to question 24 of the Hearing Aid Awareness Question Form for Parents (i.e., using the hearing aids longer) caused a 2.35-fold increase in the PEACH-NOISE subscale score, a 1.74-fold increase in the PEACH-QUIET subscale score, and a 4.06-fold increase in the overall PEACH score.</p><p><strong>Conclusion: </strong>Parent-child interaction and parents' knowledge about hearing aid use are important factors affecting hearing aid use in children. These factors also affect the children's subjective auditory performance. Parents should be given detailed information about hearing aid use and be more sensitive and responsive in their interactions with their children.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"25-36"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f8/40/tao-61-25.PMC10424585.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Technique for Use Instead of Lateral Crural Overlay for Reduction of Nasal Tip Projection in Revision Rhinoplasty. 一种替代侧脚覆盖减少鼻整形中鼻尖突出的新技术。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2022.2022-6-13
Ali Seyed Resuli, Fatih Öktem
{"title":"A New Technique for Use Instead of Lateral Crural Overlay for Reduction of Nasal Tip Projection in Revision Rhinoplasty.","authors":"Ali Seyed Resuli,&nbsp;Fatih Öktem","doi":"10.4274/tao.2022.2022-6-13","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-6-13","url":null,"abstract":"<p><strong>Objective: </strong>Correction of nasal tip projection (NTP) deformities involve techniques for the lower lateral cartilage of the nose. Previously, it would have been surgically difficult to perform the lateral crural overlay (LCO) technique for the second time in revision rhinoplasty in patients who already had undergone rhinoplasty with the LCO technique because of the length of the NTP. In this study, we evaluated the lateral crural segmental excision (LCSE) technique in patients with overprojected nasal tip in revision rhinoplasty.</p><p><strong>Methods: </strong>We retrospectively studied the cases of 19 patients who had initially undergone rhinoplasty with the LCO technique for overprojected nasal tip, and later underwent revision rhinoplasty with the LCSE technique after insufficient NTP was observed on facial analysis between 2018 and 2022.</p><p><strong>Results: </strong>Of the patients, 12 (63%) were male, with an average age of 29.6 years, and 7 (17%) patients were female, with an average age of 25.3 years. Using Goode's formula, NTP indexes of patients measured 79.4±1.8 preoperatively and 56.0±1.3 postoperatively. Stastically significant difference was observed between preoperative and postoperative values. None of the patients had malnutrition at the incision margins, and all patients recovered on time and without any problems. Granulation tissue was detected in the mucosa in only one patient.</p><p><strong>Conclusion: </strong>The LCSE technique, with a short surgical time, recovery period without complications, and satisfactory nasal respiratory function, is preferred over a second LCO application in cases of NTP.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"8-13"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/90/69/tao-61-8.PMC10424582.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10366926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Total Transcanal Endoscopic Ear Surgery for Cholesteatoma. 全经鼻内镜耳胆脂瘤手术。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2023.2022-11-6
Abdullah Dalğıç, Gökçe Aksoy Yıldırım, Mehmet Ekrem Zorlu, Orçun Delice, Abdulhalim Aysel
{"title":"Total Transcanal Endoscopic Ear Surgery for Cholesteatoma.","authors":"Abdullah Dalğıç,&nbsp;Gökçe Aksoy Yıldırım,&nbsp;Mehmet Ekrem Zorlu,&nbsp;Orçun Delice,&nbsp;Abdulhalim Aysel","doi":"10.4274/tao.2023.2022-11-6","DOIUrl":"https://doi.org/10.4274/tao.2023.2022-11-6","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the outcomes of total transcanal endoscopic cholesteatoma surgery.</p><p><strong>Methods: </strong>Twenty-seven cholesteatoma patients that had undergone transcanal endoscopic ear surgery (TEES) were included in the study. Age, sex, operation date of patients, operated side, need for ossiculoplasty, graft material, and surgical technique were recorded. All patients were evaluated through otoscopic, endoscopic, and audiological examinations and followed up for at least five months after surgery. All patients were staged using the European Academy of Otology and Neurotology/Japan Otological Society (EAONO/JOS) Staging System on Middle Ear Cholesteatoma.</p><p><strong>Results: </strong>Mean age of the patients was 36.4 years (range, 4-67 years). According to the EAONO/JOS Staging System, 11 patients were stage 1, while 11 were stage 2, and five were stage 3. Two had lateral semicircular canal defect, one had facial canal dehiscence, and one had oval window defect. The average follow-up period was 19 months (range, 5-41 months), during which two patients experienced retraction pocket and hearing loss and one patient had perforation. One patient underwent revision surgery during follow-up and no recurrence or residual cholesteatoma was observed. The preoperative and postoperative air-bone gaps were 25.14±13.93 dB and 22.22±12.64 dB with no significant difference.</p><p><strong>Conclusion: </strong>TEES is a minimally invasive and safe procedure with low complication and recurrence rates. As with all surgical procedures, experience is essential, and as experience increases, the capability to perform endoscopic otologic surgery on more complex cases may become possible.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"1-7"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a0/a7/tao-61-1.PMC10424586.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical Lipomatous Tumor Originating From the Nasopharynx in a Patient with Chronic Lymphocytic Leukemia. 慢性淋巴细胞白血病患者鼻咽部起源的非典型脂肪瘤。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2023.2023-4-1
Mehmet Emre Sivrice, Vural Akın, Bekir Büyükçelik, Hasan Yasan, Mehmet Kıran, Veysel Atilla Ayyıldız
{"title":"Atypical Lipomatous Tumor Originating From the Nasopharynx in a Patient with Chronic Lymphocytic Leukemia.","authors":"Mehmet Emre Sivrice,&nbsp;Vural Akın,&nbsp;Bekir Büyükçelik,&nbsp;Hasan Yasan,&nbsp;Mehmet Kıran,&nbsp;Veysel Atilla Ayyıldız","doi":"10.4274/tao.2023.2023-4-1","DOIUrl":"https://doi.org/10.4274/tao.2023.2023-4-1","url":null,"abstract":"<p><p>Atypical lipomatous tumor, also known as well-differentiated liposarcoma, is rare in the head and neck region. The primary and most effective option in the treatment of this malignancy with a good prognosis is excision with clean surgical margins. Therefore, it is important to distinguish this malignancy from lesions that require more aggressive treatment. In this article, we present the case of an atypical lipomatous tumor originating from the nasopharynx and almost completely obstructing the oropharynx in a 38-year-old male patient with chronic lymphocytic leukemia. To the best of our knowledge, this is the first report in the literature of an atypical lipomatous tumor case originating from the nasopharynx.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"47-51"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/43/tao-61-47.PMC10424584.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Pitfalls and Perspectives of Assessing Olfactory Function via Optical Brain Imaging. 脑光学成像评估嗅觉功能的缺陷与展望。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2023.2023-1-6
Güliz Akın Öztürk, Gizem Ermiş, Emre Eskicioğlu, Çağdaş Güdücü
{"title":"The Pitfalls and Perspectives of Assessing Olfactory Function via Optical Brain Imaging.","authors":"Güliz Akın Öztürk,&nbsp;Gizem Ermiş,&nbsp;Emre Eskicioğlu,&nbsp;Çağdaş Güdücü","doi":"10.4274/tao.2023.2023-1-6","DOIUrl":"https://doi.org/10.4274/tao.2023.2023-1-6","url":null,"abstract":"<p><p>Olfaction is critical for maintaining daily life activities. It is crucial to measure olfactory performance for the diagnosis and treatment of certain neurodegenerative diseases. Moreover, impairments and a lack of quality in the olfactory system may indicate the early diagnosis of some diseases such as Parkinson's. In this context, there are several imaging methods available for evaluating olfactory function. In addition to the conventional methods used in measuring the brain's responsiveness to olfactory stimuli, this article presents a systematic review of the current applicability of optical brain imaging (i.e., functional near-infrared spectroscopy) in the evaluation of olfactory function. A database literature search was conducted in PubMed, Scopus, the Web of Science, and ScienceDirect. This review excluded animal studies, clinical studies, pathology- or neurodegenerative disease-related studies, newborn-related studies, cross-modal- and dual-task-related studies, and non-original research studies. Thus, seven studies were examined to discuss the pitfalls and perspectives of the use of optical brain imaging under olfactory stimulation. As for this conclusion, they can be used to evaluate olfactory performance in healthy individuals through the interpretation of hemodynamic changes. Further studies are needed to standardize the applicability of these optical imaging techniques.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"37-42"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/ab/tao-61-37.PMC10424587.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10366922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coexistence of Adenoid Cystic Carcinoma and Sialolithiasis in Submandibular Gland: Case Report. 颌下腺腺样囊性癌与涎石症共存1例。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2023.2023-1-8
Vural Akın, Mehmet Emre Sivrice, Veysel Atilla Ayyıldız, Mehmet Kıran
{"title":"Coexistence of Adenoid Cystic Carcinoma and Sialolithiasis in Submandibular Gland: Case Report.","authors":"Vural Akın,&nbsp;Mehmet Emre Sivrice,&nbsp;Veysel Atilla Ayyıldız,&nbsp;Mehmet Kıran","doi":"10.4274/tao.2023.2023-1-8","DOIUrl":"https://doi.org/10.4274/tao.2023.2023-1-8","url":null,"abstract":"<p><p>Sialolithiasis is the primary cause of swelling in the major salivary glands. The etiopathogenesis is not clear. Adenoid cystic carcinoma is a slow-growing salivary gland malignancy with a poor prognosis. There are only a few cases in the literature reporting the coexistence of sialolithiasis and adenoid cystic carcinoma. In this report, we present a case that was thought to have sialolithiasis in the foreground because of the calcified image on computed tomography, but was diagnosed with adenoid cystic carcinoma after excision, together with a discussion of the relationship between sialolithiasis and carcinogenesis.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"43-46"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/14/tao-61-43.PMC10424580.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional and Aesthetic Outcomes of Asymmetric Dorsal Preservation for Correction of I-Shaped Crooked Nose Deformity. 不对称背侧保留矫治i型歪鼻的功能及美学效果。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2023.2022-12-1
Mehmet Akif Alan, Hilal Yücel
{"title":"Functional and Aesthetic Outcomes of Asymmetric Dorsal Preservation for Correction of I-Shaped Crooked Nose Deformity.","authors":"Mehmet Akif Alan,&nbsp;Hilal Yücel","doi":"10.4274/tao.2023.2022-12-1","DOIUrl":"https://doi.org/10.4274/tao.2023.2022-12-1","url":null,"abstract":"<p><strong>Objective: </strong>The study was designed to evaluate the effectiveness of the asymmetric dorsal preservation technique for correcting I-shaped crooked nose deformity (CND).</p><p><strong>Methods: </strong>Patients with I-shaped CND who underwent asymmetric dorsal preservation in the period from September 2020 to September 2021 were included in this retrospective study. The Rhinomanometry and Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) was used to assess the outcomes. Deviation angle (DA) measurements were used to evaluate the degree of crookedness. The results were recorded both preoperatively and 12 months postoperatively.</p><p><strong>Results: </strong>Twenty-three patients were included in the study. Total nasal airflow and long-side nasal airflow were significantly higher 12 months postoperatively (p=0.001 each). Total nasal resistance, long-side nasal resistance, SCHNOS scores and DA measurements were significantly lower 12 months postoperatively (p<0.001 each).</p><p><strong>Conclusion: </strong>Asymmetric dorsal preservation is a successful alternative technique for correcting I-shaped CND and achieving optimal aesthetic and functional outcomes.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"14-19"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/3b/tao-61-14.PMC10424583.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perineural Invasion of Superior and Inferior Laryngeal Nerves in Advanced Stage Squamous Cell Carcinoma of the Larynx: A Case Series and Review. 晚期喉部鳞状细胞癌对喉上、下神经的侵袭:一个病例系列和回顾。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2023-03-01 DOI: 10.4274/tao.2023.2023-2-12
Avinash Shekhar Jaiswal, Sumanth Bollu, Shilpi Budhiraja, Seema Kaushal, Kapil Sikka, Alok Thakar, Hitesh Verma
{"title":"Perineural Invasion of Superior and Inferior Laryngeal Nerves in Advanced Stage Squamous Cell Carcinoma of the Larynx: A Case Series and Review.","authors":"Avinash Shekhar Jaiswal,&nbsp;Sumanth Bollu,&nbsp;Shilpi Budhiraja,&nbsp;Seema Kaushal,&nbsp;Kapil Sikka,&nbsp;Alok Thakar,&nbsp;Hitesh Verma","doi":"10.4274/tao.2023.2023-2-12","DOIUrl":"https://doi.org/10.4274/tao.2023.2023-2-12","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate bilateral superior and recurrent laryngeal nerves for tumor spread in patients of advanced-stage laryngeal carcinoma undergoing surgical resection.</p><p><strong>Methods: </strong>A prospective study was conducted including biopsy-proven cases of laryngeal squamous cell carcinoma (SCC) that were planned for total laryngectomy. Patients with metachronous or synchronous SCC were excluded from the study. All patients underwent total laryngectomy, where both superior and recurrent laryngeal nerves were harvested along with the specimen, and the proximal ends of the nerves were marked for reference. Perineural invasion (PNI) was assessed in nerves within the tumor and in bilateral extra-laryngeal nerves.</p><p><strong>Results: </strong>The study included 22 patients with a mean age of 58 years. Intra-tumoral PNI was found in 7 of the 22 cases (32%). The free nerve margins of superior and recurrent laryngeal nerves, which were examined from proximal to distal orientation, showed no tumor infiltration in any of the cases.</p><p><strong>Conclusion: </strong>Perineural invasion of minor nerves constitutes a major pathway of spread. On the contrary, invasion of superior or recurrent laryngeal nerves does not constitute a route for tumor spread. Hence, there is no need to extend the surgical boundary for total laryngectomy to include these major nerves separately.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"61 1","pages":"20-24"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/99/tao-61-20.PMC10424581.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10366923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frontal Sinus Cholesteatoma Presenting with Intracranial and Orbital Complications: Diagnosis and Treatment. 额窦胆脂瘤伴颅内及眼眶并发症:诊断及治疗。
IF 0.6
Turkish Archives of Otorhinolaryngology Pub Date : 2022-12-01 DOI: 10.4274/tao.2022.2022-7-7
Débora Cristina Gaspar Gonçalves, Tiago Soares Santos, Vera Claúdia Miranda Silva, Hugo Narcy Amaral Amorim Costa, Carlos Magalhães Ferreira Carvalho
{"title":"Frontal Sinus Cholesteatoma Presenting with Intracranial and Orbital Complications: Diagnosis and Treatment.","authors":"Débora Cristina Gaspar Gonçalves,&nbsp;Tiago Soares Santos,&nbsp;Vera Claúdia Miranda Silva,&nbsp;Hugo Narcy Amaral Amorim Costa,&nbsp;Carlos Magalhães Ferreira Carvalho","doi":"10.4274/tao.2022.2022-7-7","DOIUrl":"https://doi.org/10.4274/tao.2022.2022-7-7","url":null,"abstract":"<p><p>Frontal sinus keratoma or cholesteatoma is a rare disease of paranasal sinuses and presents as a slow-growing mass that becomes symptomatic as it grows to the surrounding structures. Intracranial complications are not a common presentation and are potentially life-threatening. Frequently the final diagnosis is only made intraoperatively because several other frontal sinus tumors behave likewise. Definitive treatment requires complete removal of the keratoma, and a combined endoscopic and external frontal sinus approach is a good treatment option. In this report, we presented a 68-year-old female with frontal sinus cholesteatoma with diagnostic and therapeutic features of this pathology with the review of the literature.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"60 4","pages":"234-237"},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/9f/tao-60-234.PMC10339268.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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