Turkish Archives of Otorhinolaryngology最新文献

{"title":"Commentary on \"3D Model for BPPV Diagnosis and Treatment.","authors":"Melikşah Çakır, Fatih Özdoğan, Halil Erdem Özel","doi":"10.4274/tao.2024.2024-11-11","DOIUrl":"10.4274/tao.2024.2024-11-11","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 4","pages":"172-173"},"PeriodicalIF":0.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of Large Language Models as an Adjunct Tool in Healthcare.","authors":"Himel Mondal","doi":"10.4274/tao.2024.2024-10-11","DOIUrl":"10.4274/tao.2024.2024-10-11","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 4","pages":"174-175"},"PeriodicalIF":0.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity of the Turkish Version of the Tinnitus Primary Function Questionnaire.","authors":"Fatma Ceyda Akın Öcal, Hatice Kübra Bozkurt, Ceren Ersöz Ünlü, Richard Tyler, Bülent Satar","doi":"10.4274/tao.2025.2024-7-3","DOIUrl":"10.4274/tao.2025.2024-7-3","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the reliability and validity of the Turkish version of the Tinnitus Primary Function Questionnaire (TPFQ-T).</p><p><strong>Methods: </strong>The study was conducted with 103 patients who had been experiencing tinnitus for longer than three months. All participants completed the TPFQ-T, the Beck Anxiety Inventory, the Beck Depression Inventory, the Pittsburgh sleep quality index, the Tinnitus Handicap Inventory and the magnitude estimation.</p><p><strong>Results: </strong>Cronbach's alpha was 0.88. Cronbach's alpha was also computed for every one of the four subscales: a=0.67 for sleep, a=0.72 for hearing, a=0.86 for concentration, and a=0.75 for emotion. There was a correlation between the overall score obtained from the TPFQ-T and its subcategories and other questionnaires measuring corresponding factors.</p><p><strong>Conclusion: </strong>Overall, the findings of this investigation show that the TPFQ-T is both reliable and valid. As a result, the current translated version of the TPFQ-T is suitable for patients who speak Turkish as their first language and serves as an effective tinnitus questionnaire.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 4","pages":"145-150"},"PeriodicalIF":0.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tinnitus: Does it Lead to Impairments in Metacognitive Functions and the Theory of Mind Skills?","authors":"Elif Kaya Çelik, Filiz Özsoy, Büşra Yılmaz Ertürk","doi":"10.4274/tao. 2024.2024-8-4","DOIUrl":"10.4274/tao. 2024.2024-8-4","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate theory of mind skills and metacognitive functions in patients with tinnitus compared to healthy controls.</p><p><strong>Methods: </strong>This prospective study included patients diagnosed with tinnitus at our otolaryngology and Head and Neck Surgery clinic and healthy controls matching their demographic characteristics. Patients diagnosed with tinnitus at our otolaryngology and head and neck surgery clinic, along with healthy controls matched for demographic characteristics, were included in the study. All participants completed the Reading the Mind in the Eyes Test (RMET), the metacognition questionnaire (MCQ-30), the Beck Depression Inventory (BDI), and the Tinnitus Handicap Inventory (THI). The relationship between the scales applied to the patient group regarding tinnitus was evaluated using Spearman's and Pearson's correlation tests.</p><p><strong>Results: </strong>A total of 90 individuals diagnosed with tinnitus and 70 healthy controls participated in the study. There was no statistically significant difference in BDI scores between the groups (p>0.05). However, in the MCQ-30, the cognitive awareness subscale and the total score were significantly higher in the tinnitus group (p=0.003 and p=0.041, respectively). Additionally, RMET performance was lower in tinnitus patients compared to healthy controls (p=0.002). Certain subscales of the MCQ-30 showed a moderate positive correlation with THI.</p><p><strong>Conclusion: </strong>Based on these findings, we suggest that evaluating tinnitus patients from a psychiatric perspective, providing psychosocial support, and assisting them in improving their communication skills could be beneficial.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 4","pages":"131-137"},"PeriodicalIF":0.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Early Radioprotective Effect of Curcumin on the Rat Larynx.","authors":"Fatma Caner, Yusuf Çağdaş Kumbul, Özlem Özmen, Emine Elif Özkan, Hasan Yasan, Erdoğan Okur, Mehmet Emre Sivrice","doi":"10.4274/tao.2025.2024-8-2","DOIUrl":"10.4274/tao.2025.2024-8-2","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate whether the side effects of radiotherapy (RT) could be reduced by curcumin administered to rats receiving RT to the larynx.</p><p><strong>Methods: </strong>Forty male Wistar Albino rats were randomly and equally divided into four groups: RT only (Group I), RT+curcumin+dimethyl sulfoxide (Group II), RT+dimethyl sulfoxide (Group III), and curcumin+dimethyl sulfoxide (Group IV). Curcumin was administered intraperitoneally, dissolved in dimethyl sulfoxide, starting five days before RT. A single 16 Gy dose of X-ray was applied to the neck region in groups receiving RT. All groups were sacrificed on the third day after RT. Laryngeal tissues were excised and analyzed histopathologically (for edema, hyperemia, pseudostratification, necrosis, cilia loss, and inflammation) and immunohistochemically [Tumor Necrosis Factor-alpha (TNF-α) expression]. Histopathological parameters were graded as none, mild, moderate, and severe (0, 1+, 2+, 3+). The severity of TNF-α expression was scored between 0 and 3.</p><p><strong>Results: </strong>The formation of edema, hyperemia, necrosis, and pseudostratification in Group II rats was statistically significantly reduced (p=0.001, 0.003, 0.004, and 0.005, respectively). Similarly, TNF-α expression was also significantly decreased in Group II rats (p=0.009). However, no statistically significant differences were observed for cilia loss and inflammation (p=0.055 and 0.091, respectively).</p><p><strong>Conclusion: </strong>Our findings suggest that curcumin may reduce the development of edema, hyperemia, necrosis, and pseudostratification in laryngeal tissue due to RT. While further research is needed to determine whether curcumin confers protection against RT-induced damage in tumor tissues, the results of this study suggest that curcumin, a natural, non-toxic, and cost-effective dietary compound, has the potential to be used as a radioprotective agent.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 4","pages":"151-160"},"PeriodicalIF":0.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism in Chronic Rhinosinusitis with Nasal Polyps.","authors":"Mehmet Emre Sivrice, Vural Akın, Hasan Yasan, Kuyaş Hekimler Öztürk, Yusuf Çağdaş Kumbul","doi":"10.4274/tao.2024.2024-4-4","DOIUrl":"10.4274/tao.2024.2024-4-4","url":null,"abstract":"<p><strong>Objective: </strong>Inflammatory processes play a role in the etiopathogenesis of chronic rhinosinusitis. Many gene polymorphisms have been associated with inflammation. In this study, we aimed to examine the relationship between angiotensin-converting enzyme insertion/deletion gene polymorphism and chronic rhinosinusitis.</p><p><strong>Methods: </strong>Fifty-two cases with nasal polyps and 139 control patients were included in the study. Angiotensin-converting enzyme insertion/deletion gene polymorphisms, genotype, and allele distributions were determined. Results were statistically compared between groups.</p><p><strong>Results: </strong>Statistically significant differences were found between the chronic rhinosinusitis with nasal polyps group and the control group in terms of genotype and allele distribution (p=0.015, 0.003, respectively). There were no significant differences in genotype distribution in the chronic rhinosinusitis with nasal polyps group in terms of non-steroidal anti-inflammatory drug (NSAID) allergy, asthma, and NSAID-exacerbated respiratory disease (p=0.645, 0.660, 0.095, respectively).</p><p><strong>Conclusion: </strong>We observed that the risk of chronic rhinosinusitis is higher in individuals with the deletion-deletion genotype and D allele of the angiotensin-converting enzyme insertion/deletion gene polymorphism. We believe that these results could be related to the high angiotensin-converting enzyme levels in these patients.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 3","pages":"95-100"},"PeriodicalIF":0.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Acute Otitis Media Complication: Luc's Abscess.","authors":"Meltem Akpınar, Beyza Demirci","doi":"10.4274/tao.2024.2024-2-4","DOIUrl":"10.4274/tao.2024.2024-2-4","url":null,"abstract":"<p><p>Otitis media, a common childhood disease, can lead to serious complications such as acute mastoiditis and, rarely, Luc's abscess, with life-threatening consequences. Luc's abscess, a rare but severe complication, can occur without acute mastoiditis. This case report details a case of Luc's abscess in a 14-year-old girl with acute otitis media, presenting with ear pain, facial swelling, and hearing loss. Treatment involves a multidisciplinary approach, considering factors like age and abscess extent. Though there is no established standard treatment, this case emphasizes the need for prompt recognition and appropriate intervention to prevent severe complications. This case report emphasizes the importance of tailored, timely interventions for optimal outcomes in affected children.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 3","pages":"120-123"},"PeriodicalIF":0.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Sphenopalatine Artery Cauterization Under Local Anesthesia for Posterior Epistaxis: A Prospective Cohort Study of its Tolerability and Efficacy.","authors":"Urmila Gurung, Narmaya Thapa, Sajish Khadgi","doi":"10.4274/tao.2024.2024-5-2","DOIUrl":"10.4274/tao.2024.2024-5-2","url":null,"abstract":"<p><strong>Objective: </strong>To assess the tolerability and efficacy of endoscopic sphenopalatine artery cauterization (ESPAC) under local anesthesia (LA) in managing posterior epistaxis.</p><p><strong>Methods: </strong>It was a prospective, cohort study, conducted in the Otorhinolaryngology Department of a tertiary-level hospital. Patients aged 18 years or above with posterior epistaxis who underwent ESPAC under LA were included. The tolerability of the procedure was reflected by the intraoperative pain measured using an 11-point numerical rating scale while the rebleed rate up to three months postoperatively denoted its efficacy.</p><p><strong>Results: </strong>A total of 35 patients, 23 males and 12 females, aged 31 to 86 years (mean 57.42 ± 12.94) were included. Five out of 35 (14.2%) patients needed additional procedures besides ESPAC; 82.8% (29/35) had pterygopalatine fossa (PPF) block before ESPAC. The numerical rating scale reflecting the intraoperative pain ranged from 1 to 7 with a mean of 3.6 (± 1.7). The mean score was slightly higher in females than in males. Similarly, those who did not receive PPF block had a higher mean score than those who received it; however, the differences were not statistically significant. Meanwhile, the mean score was the same (3.6) irrespective of any additional procedure besides ESPAC. Amongst the 30 patients who completed the three-month follow-up, two patients rebled, so the overall success rate amounted to 93.3% in three months.</p><p><strong>Conclusion: </strong>Based on the outcome of this study, ESPAC under LA for posterior epistaxis is well tolerated and is as efficacious as under general anesthesia.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 3","pages":"88-94"},"PeriodicalIF":0.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Prospective Comparative Analysis of Ototoxic and Survival Outcomes of Sequential Boost and Simultaneous Integrated Boost of Volumetric Modulated Arc Therapy for Head-Neck Carcinomas.","authors":"Nidhin Das, Sri Harsha Kombathula, Vidhu Sharma, Puneet Pareek, Kapil Soni, Amit Goyal","doi":"10.4274/tao.2024.2023-10-10","DOIUrl":"10.4274/tao.2024.2023-10-10","url":null,"abstract":"<p><strong>Objective: </strong>To compare the ototoxicity and survival in head and neck carcinoma patients treated with sequential (SEQ) and simultaneous integrated boost (SIB) of volumetric modulated arc therapy (VMAT).</p><p><strong>Methods: </strong>This long-term prospective study enrolled patients with histologically confirmed head and neck carcinoma, all receiving VMAT treatment. Audiological assessments were done using various tests at baseline, two weeks, treatment completion, six months, and 12 months. The changes in bone conduction pure tone thresholds were correlated with cochlear dose, comparing SEQ and SIB plans. We also investigated other significant late toxicities that led to dysphagia, voice changes, and xerostomia. Survival was assessed with the Kaplan-Meier analysis.</p><p><strong>Results: </strong>The study included 93 patients (186 ears), 40 receiving radiation alone and 53 undergoing chemoradiation. Baseline hearing levels for the right and left ears were 13.3±2.3 dB and 14.2±1.5 dB. After 12 months of radiation, levels were 18.5±2.4 dB and 19.11±1.9 dB, respectively. No significant changes were observed between SEQ and SIB plans, but high-frequency shifts occurred. The cochlea tolerated up to 28 Gy without hearing loss in the radiation-alone group but showed loss at 9 Gy when combined with cisplatin chemotherapy. The maximum dose (Dmax) and the mean dose (Dmean) of pharyngeal constrictor muscles predicted dysphagia. No significant SEQ vs. SIB differences were found in late toxicity or survival outcomes.</p><p><strong>Conclusion: </strong>Modern radiotherapy techniques like VMAT adhere to cochlear dose limits. No significant differences were found between SEQ and SIB plans in sensorineural hearing loss, late toxicity, or survival, making both suitable for head and neck carcinoma treatment.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 3","pages":"101-112"},"PeriodicalIF":0.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors of Post-Tonsillectomy Bleeding and Differences Between Children and Adults: Implications for Risk Assessment.","authors":"Bülent Öcal, Mehmet Murat Günay, Kemal Keseroğlu, Murad Mutlu, İlker Akyıldız, Cem Saka, Emel Çadallı Tatar, Mehmet Hakan Korkmaz","doi":"10.4274/tao.2024.2023-10-2","DOIUrl":"10.4274/tao.2024.2023-10-2","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between clinical factors and post-tonsillectomy hemorrhage (PTH) including rebleeding episodes.</p><p><strong>Methods: </strong>The medical records of 1,082 patients who underwent tonsillectomy between May 2018 and April 2019 were reviewed. The entire study cohort included 431 (39.7%) children aged less than six years and 292 (26.9%) adults older than 15 years. Data on patient demographics, surgical indication, dissection technique, tonsils' grade, postoperative analgesia, surgeon's experience, the season of surgery, management of hemorrhage, length of hospital stay, and rebleeding episode were noted.</p><p><strong>Results: </strong>Postoperative hemorrhage occurred in 87 cases (8.0%) including 32 children (4.0% of children) and 55 adults (18.8% of adults). Age, surgical indication, tonsils' grade, and postoperative use of non-steroidal anti-inflammatory drugs (NSAIDs) were risk factors found to be statistically significant for PTH in univariate analysis (p<0.05). Multivariable analyses identified patients older than 15 years and those who received postoperative NSAIDs to be risk factors of PTH [Odds ratio (OR): 15.5, 95% confidence interval (CI): 7.68-31.27, p<0.001, OR: 0.22, 95% CI: 0.11-0.44, p<0.001, respectively]. About one out of every 60 (1.5%) children had severe oropharyngeal bleeding, whereas every 12^th (8.2%) patient of those aged >15 years had severe hemorrhages that warranted surgical hemostasis in the operating room (p<0.001).</p><p><strong>Conclusion: </strong>The risk of bleeding after tonsillectomy was significantly higher in adults and users of NSAIDs postoperatively. Also, the evidence of minor bleeding increased the risk of a second bleeding episode in adulthood.</p>","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":"62 3","pages":"81-87"},"PeriodicalIF":0.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}