Journal of medical and bioengineering最新文献

Detection of Pre-stage of Epileptic Seizure by Exploiting Temporal Correlation of EMD Decomposed EEG Signals 利用EMD分解脑电图信号的时间相关性检测癫痫发作前期

Journal of medical and bioengineering Pub Date : 2015-04-01 DOI: 10.12720/JOMB.4.2.110-116

M. Parvez, M. Paul, M. Antolovich

{"title":"Detection of Pre-stage of Epileptic Seizure by Exploiting Temporal Correlation of EMD Decomposed EEG Signals","authors":"M. Parvez, M. Paul, M. Antolovich","doi":"10.12720/JOMB.4.2.110-116","DOIUrl":"https://doi.org/10.12720/JOMB.4.2.110-116","url":null,"abstract":"Epilepsy is one of the common neurological disorders characterized by a sudden and recurrent malfunction of the brain that is termed \"seizure\", affecting over 50 million individuals worldwide. The Electroencephalogram (EEG) is the most influential technique in detection of epileptic seizures. In recent years, many research works have been devoted to the detection of epileptic seizures based on analysis of EEG signals. Despite remarkable work on seizure detection, there is no generic seizure detection scheme which performs reasonably well for different patients and different brain locations. In this paper we present a generic approach for feature extraction of preictal (pre-stage of seizure onset) and interictal (period between seizures) EEG signals using empirical mode decomposition (EMD) along with discrete cosine transformation (DCT) by exploit temporal correlation for detection of preictal phase of epileptic seizure. Then least square support vector machine is applied on the features for classifications. Results demonstrate that our proposed method outperforms the state-of-the-art methods in terms of sensitivity, specificity and accuracy to classify preictal and interictal EEG signals to the benchmark dataset extracted from different brain locations of different patients. ","PeriodicalId":437476,"journal":{"name":"Journal of medical and bioengineering","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127628121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Bioeconomy: Pectinases Purification and Application of Fermented Waste from Thermomyces Lanuginosus 生物经济:热酵母菌发酵废液的果胶酶纯化及应用

Journal of medical and bioengineering Pub Date : 2015-02-01 DOI: 10.12720/JOMB.4.1.76-80

E. Makky, M. Yusoff

{"title":"Bioeconomy: Pectinases Purification and Application of Fermented Waste from Thermomyces Lanuginosus","authors":"E. Makky, M. Yusoff","doi":"10.12720/JOMB.4.1.76-80","DOIUrl":"https://doi.org/10.12720/JOMB.4.1.76-80","url":null,"abstract":"Malaysia takes a step forward to promote and support the development of sustainable and green technology by adopting and master the technology holistically. Bioeconomy refers to all economic activity derived from scientific and research activity focused on biotechnology. Pectin degradation enzymes are widely used in the industrial processing of fruits and vegetables in order \u0000to decrease the viscosity of juices and thus to facilitate \u0000extraction, maceration, liquefaction, filtration and \u0000clarification processes. Sugar-cane bagasse (SCB) is agrowaste produced in large quantities in our environment used as the substrate for Exo-polygalacturonase (Exo-PG) from Thermomyces lanuginosus at 55°C under solid-state \u0000fermentation (SSF) culture. Exo-PG was purified using Gelfiltration chromatography and exhibited only one sharp \u0000peak. Biotechnological applications of fermented waste \u0000obtained, mixed with the fungal biomass at 55°C as \u0000biofertilizer at different concentrations (w/w) were \u0000cultivated with Zea mays for 30 days to indicate the plant \u0000growth on sandy soil and succeeded to induce the growth \u0000which may give an indication of applying the present \u0000biofertilizer particularly in the reclaimed sandy soils. Only 14 amino acids were detected and obviously that Exo-PG \u0000was typical proline containing enzyme.","PeriodicalId":437476,"journal":{"name":"Journal of medical and bioengineering","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130860327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The effect of temperature and pressure on the self-assembly of dipalmitoylphosphatidylcholine using coarse-grained molecular dynamics 用粗粒度分子动力学研究温度和压力对双棕榈酰磷脂酰胆碱自组装的影响

Journal of medical and bioengineering Pub Date : 2014-06-01 DOI: 10.12720/JOMB.3.2.122-127

N. Shaari, R. A. Karjiban, M. Basri

引用次数: 1

The Role of Urinary Cadmium and Lead Level on Pregnant Women Renal Function 尿中镉、铅水平对孕妇肾功能的影响

Journal of medical and bioengineering Pub Date : 2014-03-01 DOI: 10.12720/JOMB.3.1.55-58

A. Wibowo, Firrar Artmi Rahaju, Rizky Taufan Firdaus, E. Suhartono

引用次数: 10

The Role of cadmium in proteins glycation by glucose formation of methylglyoxal and hydrogen peroxide in vitro 镉在葡萄糖形成甲基乙二醛和过氧化氢的蛋白质糖基化中的作用

Journal of medical and bioengineering Pub Date : 2014-03-01 DOI: 10.12720/JOMB.3.1.59-62

E. Suhartono, T. Triawanti, A. Leksono, M. Djati

{"title":"The Role of cadmium in proteins glycation by glucose formation of methylglyoxal and hydrogen peroxide in vitro","authors":"E. Suhartono, T. Triawanti, A. Leksono, M. Djati","doi":"10.12720/JOMB.3.1.59-62","DOIUrl":"https://doi.org/10.12720/JOMB.3.1.59-62","url":null,"abstract":"Cadmium (Cd) is a heavy metal that be a source of concern for industrial workers and it was proposed in the formation of advance glycation end products (AGEs) such as methylglyoxal (MG). MG have recently attracted much attention because of their possible clinical significance in chronic and agerelated diseases. Based on previous research, methylglyoxal formation can be accelerated by metals in vitro. The role of Cd in the formation of MG and hydrogen peroxide has not been much studied. Thus, our study aims to measure the formation rate of MG and hydrogen peroxide in the presence of Cd in vitro. This research was divided into 4 groups (1 control group and 3 treatment groups), than we set carbonyl compound assay, methylglyoxals assay, and hydrogen peroxide assay. For analyzing of the data, SPSS software version 17 was used and was examined by ANOVA and regression correlation test. For all outcomes, a nominal p-value of p < 0,05 was considered significant. We found that there are significant correlation between Cd exposure on the formation of hydrogen peroxide and methylglyoxal (p < 0,05) in nonenzymatic glycation of proteins by glucose. The increased Cd level accelerate the formation of methylglyoxal and hydrogen peroxide.","PeriodicalId":437476,"journal":{"name":"Journal of medical and bioengineering","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131925576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Comparison between a Camera and a Four Quadrant Detector, in the Measurement of Red Blood Cell Deformability 照相机与四象限检测器在红细胞变形性测量中的比较

Journal of medical and bioengineering Pub Date : 2013-03-01 DOI: 10.12720/JOMB.2.1.62-65

A. Finkelstein, Hugues Talbot, S. Topsu, T. Cynober, L. Garçon, Gregor Havkin, F. Kuypers

{"title":"Comparison between a Camera and a Four Quadrant Detector, in the Measurement of Red Blood Cell Deformability","authors":"A. Finkelstein, Hugues Talbot, S. Topsu, T. Cynober, L. Garçon, Gregor Havkin, F. Kuypers","doi":"10.12720/JOMB.2.1.62-65","DOIUrl":"https://doi.org/10.12720/JOMB.2.1.62-65","url":null,"abstract":"The ability of red blood cells (RBC) to deform under vascular conditions is essential for circulation. RBC deformability, measured at different shear rates and osmolalities, provides a useful way to evaluate RBC function and is used to diagnose several hereditary blood disorders. In clinical practice, ektacytometry has been used as a routine automated technique for measuring RBC deformability under shear stress at known osmolalities. RBC suspension is exposed to laser light and the resulting diffraction pattern is recorded. The mean deformability of the cells is characterized by the diffraction pattern. Our study is the first to compare the correspondence between two methods that measure diffraction simultaneously, on the same apparatus. Additionally, while others conducted studies under varying shear we used varying osmolalities. A laser beam splitter produced two identical diffraction patterns, evaluated by synchronous data acquisition and analysis: One pattern was acquired by a digital camera and analyzed by image processing software. The other was analyzed using photodiode measurement at four fixed points and a microcontroller interface. Data analysis resulted in two deformability vs. osmolality curves. Comparing these curves shows excellent overlap in shape with a clear difference in amplitude. Since routine Manuscript received Jan 15, 2013; revised March 1, 2013. patient curves are always compared to a normal control curve, the amplitue difference is not significant. Our results indicate that either method may be used for clinically-usable interpretation of RBC deformability, but also that additional studies are required in order to compare repeatability for both methods, and to demonstrate that the two curves overlap for a variety of pathologies.","PeriodicalId":437476,"journal":{"name":"Journal of medical and bioengineering","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116514511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Real-Time Decision Support in Intensive Medicine: An intelligent approach for monitoring Data Quality 强化医学中的实时决策支持:监测数据质量的智能方法

Journal of medical and bioengineering Pub Date : 2013-03-01 DOI: 10.12720/JOMB.2.1.26-31

Filipe Portela, M. Santos, J. Machado, A. Abelha, Álvaro M. Silva, Fernando Rua

引用次数: 4

Analysis of Straight Vegetable Oil (SVO) Spray Characteristics at End of Injection (EOI) 直馏植物油(SVO)喷注末(EOI)喷雾特性分析

Journal of medical and bioengineering Pub Date : 2012-09-01 DOI: 10.12720/JOMB.1.1.59-62

A. Abdullah, R. Mamat, R. Atiqah, Kidoguchi Yoshiyuki, Z. Azran

{"title":"Analysis of Straight Vegetable Oil (SVO) Spray Characteristics at End of Injection (EOI)","authors":"A. Abdullah, R. Mamat, R. Atiqah, Kidoguchi Yoshiyuki, Z. Azran","doi":"10.12720/JOMB.1.1.59-62","DOIUrl":"https://doi.org/10.12720/JOMB.1.1.59-62","url":null,"abstract":"The depletion source and the increasing demand of fossil fuel have prompted scientists and researchers to search new alternative fuels for diesel engine. Biodiesel is seen a promising alternative fuel to reduce dependent on conventional diesel fuel. Advantages of biodiesel compared to petroleum-based diesel include high biodegradability, excellent lubricity, higher flash point, no sulfur content and produces less air pollutants. Although biodiesel has many advantages on the fuel properties, the fuel consumption rate or lower horsepower output are still need to be improved. This is due to the differences in fuel properties especially the kinematic viscosity between diesel fuel (GO), biodiesel fuel (BDF) and straight vegetable oil (SVO). In this study, the effect of kinematic viscosity of SVO on the spray behavior at End of Injection (EOI) were investigated. High kinematic viscosity of fuel highly affects the spray characteristics at EOI. In additional, high injection pressure and high kinematic viscosity of SVO apply resistance at nozzle inner hole caused needle lift cannot completely close the nozzle at EOI signal. At the EOI in which the combustion temperature inside chamber reduces promptly, many fuel droplets could not undergo a complete atomization process especially for large size of diameter fuel droplets. This phenomenon result the development of carbon deposition around the nozzle tip area and it will cover the nozzle hole. The development of carbon deposition will affect the fuel flow from nozzle. This study indicates that fuel injection pressure show no effect on SVO spray characteristics at the end of injection. Furthermore, high ambient temperature spray will reduce the kinematic viscosity value of SVO and could improve SVO spray atomization at end of injection.","PeriodicalId":437476,"journal":{"name":"Journal of medical and bioengineering","volume":"369 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113994795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Comparing Contribution of Algorithm Based Physiological Indicators for Characterisation of Driver Drowsiness 基于算法的生理指标对驾驶员困倦特征的贡献比较

Journal of medical and bioengineering Pub Date : 1900-01-01 DOI: 10.12720/jomb.4.5.391-398

Manuel Rost, E. Zilberg, Z. Xu, Yue Feng, D. Burton, S. Lal

{"title":"Comparing Contribution of Algorithm Based Physiological Indicators for Characterisation of Driver Drowsiness","authors":"Manuel Rost, E. Zilberg, Z. Xu, Yue Feng, D. Burton, S. Lal","doi":"10.12720/jomb.4.5.391-398","DOIUrl":"https://doi.org/10.12720/jomb.4.5.391-398","url":null,"abstract":"The algorithm based physiological characteristics of driver drowsiness – ocular parameters (derived from the frontal electroencephalogram (EEG)), EEG alpha bursts and spectral power (derived from the central and occipital sites) as well as heart rate variability (HRV) were estimated from data derived during a driving simulator experiment (30 non-professional drivers). The statistical associations of these parameters with the “gold standards” of driver drowsiness were investigated using linear regression and linear mixed models. The statistical models were also examined for a number of hybrid algorithms, which combined multiple characteristics of driver drowsiness. A combination of ocular parameters showed the strongest association (R=0.48) with the applied trained observer rating (TOR) method; followed by EEG alpha bursts indicators (R=0.30) and EEG spectrum data (R=0.21). The HRV parameters showed a weak association (R=0.04) A joint model including the eye parameters and the EEG alpha bursts resulted in the highest R=0.54 to TOR. The results indicate that a hybrid automatic algorithm, based on multiple characteristics of the eye blinks and EEG patterns, but not necessarily including the HRV measures, is likely to achieve a level of accuracy in characterising driver drowsiness similar to that of a trained observer.","PeriodicalId":437476,"journal":{"name":"Journal of medical and bioengineering","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117103395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Restriction Enzymes ApaI Analysis to Find A3243G Mutation in Indonesia Diabetes Mellitus Type II Patients 印尼型糖尿病患者A3243G突变的限制性内切酶ApaI分析

Journal of medical and bioengineering Pub Date : 1900-01-01 DOI: 10.12720/jomb.4.6.492-496

R. A. Chandra, Sriwidodo, Ajeng Diantini, I. Maksum

引用次数: 3