Asian Pacific Journal of Cancer Care最新文献

{"title":"An Approach to Cancer Patients in the Covid-19 Pandemic Era","authors":"T. Tali, Fiza Amin, S. Rashid, M. Sofi, N. Dar, J. Dar","doi":"10.31557/apjcc.2023.8.2.385-389","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.385-389","url":null,"abstract":"The aim of this article is to give an overview of an approach to cancer patients in the covid-19 pandemic. The treatment recommendations are prioritized as per the risk stratification till the current crisis is mitigated. Measures like telemedicine/telecommunication, triage system, proved to be very effective in prevention of covid contact of cancer patients. Guidelines and protocols are needed that can decrease the risks in cancer management in such pandemic times. Multi-disciplinary work and effective communication between oncology team, critical care and emergency units is the key to optimizing clinical care of cancer patients.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116048229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness of Risk Factors for Breast Cancer among Casablanca Medical Students","authors":"Bendahhou Karima, Serhier Zineb, Diouny Samir, Bennani Othmani Mohamed","doi":"10.31557/apjcc.2023.8.2.311-317","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.311-317","url":null,"abstract":"Background: Socio-economic burden of breast cancer is substantial in low and middle income countries. Therefore, preventive measures are necessary, including raise of population awareness and education on the risk factors. This study aims to assess the general awareness of cancer among Casablanca medical students, with a focus on risk factors for breast cancer. Methods: A cross sectional study using a questionnaire on risk factors of breast cancer was carried out. Participants were randomly selected using a stratified sampling. Results: A total of 678 students participated in the survey. Just over half of the cases (53.2%) reported knowing breast cancer risk factors with a 95% confidence interval of [49.5%; 57.0%]. The main sources of information regarding their knowledge of breast cancer risk factors reported by students were represented by the faculty and media with a similar proportion of 20.6% of cases. The average number of correct responses was statistically different depending on the students’ level of education and whether they had a family history of cancer. Indeed, the average correct responses increased with the year of study, so the lowest average was noted among first-year students with 11 responses versus 15 correct responses out of 23 among sixth-year students and a degree of significance less than 0,001. Similarly, for those who reported a family history of cancer, their average correct response was 14.4 versus 13.2 for those having no relatives with cancer (p< 0.001). Conclusion: Our medical students’ knowledge on breast cancer risk factors is very weak. These future doctors play an important key role in educating people and raising awareness on breast cancer in our country. Therefore, priority programs and training should be put in place to insure successful and knowledgeable doctors.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126029756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Group Characteristics in Rectal Cancer. A study Conducted in a Tertiary Care Center, Srinagar, Kashmir, India","authors":"Dar Abdul Waheed, M. Wani, Irfan Rasool Gadda, Syed Arshad Mustafa","doi":"10.31557/apjcc.2023.8.2.307-310","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.307-310","url":null,"abstract":" Introduction: Rectal cancer is the third most common cancer in the world. Tumors are most commonly located in the rectosigmoid region. There are many actors in the etiology such as age, geographical features, family history, obesity, diet, and history of malignancy. Blood groups are one of the controversial etiologic factors in CRC. Blood group antigens, covered by Karl Landsteiner in 1901, have been the subject of numerous cancer studies since 1953, when Aird declared that blood group A was associated with stomach cancer. Aim: In the present study, we aimed to determine the effect of blood group characteristics, which play a role in the etiology of Rectal cancer. Method: We Prospectively reviewed the patients who were diagnosed with CRC and operated in our center or at other centers and were followed postoperatively at our centers. Age, gender, histologic TNM stage (tumor, lymph node involvement, and metastasis), tumor-bearing colonRectal segment, ABO blood group, and Rh antigen were examined from the patients’ records. Results: Total of 60 patients with histopathologically confirmed as rectal cancers formed the study population. The male to female ratio in rectal cancers was 1.7:1. The age group varied from 16 to 80 years with most common age group in rectum cancer were between age is 45-64 years constituted (29) 48%. However, we observed relationship in the present study between Rh antigen and lymph node metastasis, liver metastasis, or TNM stage. O Blood group and rh positive was associated with lymph node involvement, higher TNM stage, and also found that risk of liver metastasis. Conclusion: As in Rectal cancer, our findings show that the O (+) blood group is a risk factor in rectal cancers, which have multifactorial etiology. Further genetic studies are needed. \u0000  \u0000 ","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126536777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Postoperative Outcomes of Extremity Tumors During the COVID-19 Era in a Developing Country – Is Limb Salvage a Viable Option?","authors":"Ma. Loren Josephine Lantin, Mamer Rosario, John Ricardo Chua, A. Alomesen, Mahima Jose, Geoffrey Battad","doi":"10.31557/apjcc.2023.8.2.281-279","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.281-279","url":null,"abstract":"Background: With advancements in surgical techniques and adjuvant therapies, limb salvage (LS) has replaced amputation as the dominant treatment model for malignancies involving the extremities. But the COVID-19 pandemic has drastically affected cancer care especially in developing countries, with treatment delays possibly leading to a rise in amputations. Due to a lack of consensus regarding the ideal course of treatment for tumors involving the extremities in the current situation, the present study aimed to evaluate perioperative and short- term functional outcomes following LS surgery during the COVID-19 pandemic. Methods: A single-institutional series of 45 patients who underwent surgical resection for extremity tumors and followed for at least 6 weeks after operation were included. We analyzed patients according to whether one had LS or major amputation during surgery, and compared intraoperative blood loss, operative duration, perioperative complication rates, COVID-19 infection rates, and Musculoskeletal Tumor Society (MSTS) scores during last follow-up, between the two groups. Results: The LS group (n=21) had significantly longer operative duration (323 min vs. 214 min, p=.004) but higher MSTS scores (81% vs. 49%, p=.001) than the amputation group (n=24). Intraoperative blood loss (1113 mL vs. 779 mL, p=.46), superficial infection rates (14% vs. 8%, p=.12), and COVID-19 infection rates (14% vs. 29%, p=.23) were similar between the two groups. Conclusion: The authors conclude that LS surgery can be a viable option for treating tumors involving the extremities especially in developing countries in the COVID-19 era.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114844159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in Vitamin D Levels at Diagnosis and after Induction Phase Chemotherapy in Children with Acute Lymphoblastic Leukemia in Tertiary Hospital in West Java Indonesia","authors":"Wan Rita Mardhiya, Nur Suryawan, B. Setiabudiawan","doi":"10.31557/apjcc.2023.8.2.295-300","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.295-300","url":null,"abstract":"Objective: We examined differences of vitamin D levels at initial diagnosis and after induction phase chemotherapy in children with Acute Lymphoblastic Leukemia (ALL). Methods: A cross-sectional study was conducted on newly diagnosed children with ALL from October 2021 until October 2022 at Dr. Hasan Sadikin Hospital−Bandung, West Java, Indonesia. Vitamin D levels were measured twice using blood samples: at initial diagnosis and after the remission induction phase of chemotherapy. A paired t-test was applied and the value of p<0.05 is considered as statistically significant. Result: There were 53 subjects that fulfilled research criteria. Thirty−six subjects met the inclusion criteria while 17 were excluded. Majority of ALL patients were male (52.8%) and aged 1−10 years (83.3%). Mean vitamin D level of ALL children at initial diagnosis was 16.68±9,56 ng/mL. After the induction phase of chemotherapy, mean vitamin D level was 11.84±7,8 ng/mL. Paired t-test was performed to obtain p value = 0.000. Conclusion: The prevalence of hypovitaminosis D in ALL children is 88.8%. Vitamin D levels after chemotherapy are lower than at initial diagnosis.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128016577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensity Modulated Radiotherapy (IMRT) Versus Helical Tomotherapy (HT) in Esophageal Cancer: A Comparative Analysis","authors":"M. Penumur, Smriti Goswami, B. Goswami, D. Choudhury, F. A. Hassan, G. Bora, L. Borah, Moumita Paul, Rheetwik Baruah, D. Saikia, Kalyanjit Dutta Baruah","doi":"10.31557/apjcc.2023.8.2.301-306","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.301-306","url":null,"abstract":"Purpose/Objectives: Definitive chemoradiation is an accepted alternative treatment in the management of esophageal cancer in patients who are not candidates for surgery. The location of esophagus poses a challenge because of its close proximity to the critical organs. Various modern techniques of radiation planning offer the advantage of better dose conformality and increased sparing of organs at risk. This study aims to compare the dosimetric parameters of Intensity Modulated Radiotherapy (IMRT) and Helical Tomotherapy (HT) planning techniques in radical radiotherapy for esophageal cancer patients. Materials/Methods: A total of 38 patients of esophageal squamous cell carcinoma with clinical staging cT2-T4/N0-N2/M0 planned for definitive chemoradiation were enrolled from June 2021 till November 2022. CT simulation was done with intravenous and oral contrast, and contouring of tumor volumes and organs at risk were done according to RTOG contouring guidelines. All patients were planned for a total dose of 50.4Gy in 28 fractions. Radiation plans of IMRT and HT were generated for each patient. Dosimetric parameters of PTV D98, D2, Dmean, V95, V110, Homogeneity Index (HI) and Conformity Index (CI) were noted for both the plans. Organs at risk (OAR) parameters such as Lung (V20, V30, V5, Dmean), Heart (V25, V30, Dmean), Spinal Cord Dmax, Larynx (Dmax, Dmean) and Liver Dmean were noted. All parameters of the two different planning techniques were compared and analyzed using SPSS software v23 with paired t-test.Results: The coverage of the PTV in IMRT and HT was similar in terms of PTV V95 and PTV D98. The regions receiving more than 107% and 110% of the prescribed dose was significantly higher in IMRT compared to HT, on assessing V107, V110 and D2 (p=0.001). HI was similar in both the groups, but the CI was significantly better in HT compared to IMRT (0.9 ± 0.02 vs 1.03 ± 0.01; p=0.002). Doses to the lungs, heart and liver were similar between the two groups. IMRT had higher spinal cord (39.1 ± 3.2 vs 34.2 ± 5.5; p=0.001) and laryngeal dose (9.6 ± 5.5 vs 5.6 ± 3.7; p=0.009) compared to HT.Conclusion: HT offers better dose conformality and uniformity when compared to IMRT with lesser dose to spinal cord and larynx. As this is a dosimetric study, a larger sample size and patient follow up is essential for clinical correlation and assessment of benefit of different radiation modalities.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114198596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal Stromal Tumor Coexistence with Multiple Myeloma: A Case Report","authors":"E. Sundarita, Y. D. Andayani, M. Syahrir, Norman Djamaluddin","doi":"10.31557/apjcc.2023.8.2.435-436","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.435-436","url":null,"abstract":"Objectives: Gastrointestinal stromal tumor (GIST) is a tumor that is rarely found and is characterized by positive KIT (CD117) and DOG1 results. Multiple myeloma (MM) is characterized by malignant proliferation of uncontrolled plasma cells in the bone marrow which produces abnormal proteins in plasma or urine. The coexistence of GIST and other solid cancers in the gastrointestinal tract and urinary tract have been widely reported, but GIST coexistence with hematologic malignancies is a scarce case.Methods: Case Report. Results: Immunochemistry plays an important role in determining the diagnosis and treatment of GIST. Concomitant therapy between GIST dan MM gives good results. Conclusion: The management of both diagnoses is carried out simultaneously while considering the possibility of various side effects that arise. For GIST, given target therapy with Imatinib mesylate which is the selected target therapy, while for MM given conventional therapeutic regimens according to the patient's age and ability. In the condition of coexistence of the two types of disease, the management of the disease that most influence the quality of life with a worse prognosis, is made as the main target of initial treatment.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"17 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131426358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant Tumor of the Mandible – Secondary Leading to Primary: A Case Report with the Review of the Literature","authors":"Anuradha Yadav, Nandini Goswami, Roopika Handa, S. Agarwal","doi":"10.31557/apjcc.2023.8.2.437-439","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.437-439","url":null,"abstract":"Metastatic adenocarcinoma of jaw-bone accounts for 1-3% and is commonly seen in the fifth and sixth decades. Most metastases of the oral cavity from primary locations have been described in the lungs, breasts, kidneys, and colon in adult patients. Oral Clinicians apart from diagnosing systemic diseases like diabetes, gastrointestinal disorders etc, could be the first ones to diagnose malignancies of different parts of the body before any oncologist and general physicians. Specialized imaging like PET/CT aids in diagnosing the primary tumor in such cases. To increase the survival time of such patients extensive mandibulectomy followed by other multimodal treatment options like palliative care should be considered. Here, in this paper, we aim to present a case of a young 24-year- old female with a metastatic tumor of the mandible that ultimately gave us the roadmap for diagnosing the primary tumor of the breast and also to review the literature of such cases.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115110124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Announcement of First Successfully Pregnancy Following Abdominal Radical Trachelectomy in Viet Nam","authors":"N. T. Doan, T. Nguyen, L. Ta, Nhi Tien Tan Vo, T. D. Nguyen, Thinh Xuan Minh Phan, Phuc Huu Nguyen","doi":"10.31557/apjcc.2023.8.2.407-409","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.407-409","url":null,"abstract":"Objectives: Abdominal radical trachelectomy (ART) is an alternative treatment for preserving fertility in selected patients with early - stage cervical cancer. This report to announce one case of successful conceive and gave birth following the abdominal radical trachelectomy. Materials and Methods: We have performed 12 cases of radical trachelectomy with pelvic lymphadenectomy in The Oncology Hospital of Ho Chi Minh city between January 2018 and December 2022. One of them has successful live birth after procedure about six months.Results: The characteristics of the 12 adult patients, who underwent radical trachelectomy, included stage IB1 disease in all cases, a mean age of 31 years (range, 29–41), and a median estimated blood loss of 100 ml (range, 70–150). No one needed adjuvant treatments after surgery, and all cases resumed normal menstruation postoperatively. There were no intraoperative complications. Transurethral Foley catheters were removed in all cases at postoperative days 02 – 04. Cervical stenosis was observed in one case. One case had successfully conceived and gave births following the abdominal radical trachelectomy. All patients remain disease-free after a median 3 - year follow-up. Conclusions: ART with pelvic lymphadenectomy is a feasible operation for selected women with early-stage cervical cancer cases who desire to preserve reproductive function. Menstruation and reproductive function might be preserved after bilateral uterine vessel ligation.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133114849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer Stigma in Non-patient Population Visiting B&B Hospital, Lalitpur, Nepal: A Descriptive Cross-sectional Study","authors":"R. Shrestha, Gambhir Shrestha, Pragya Paneru","doi":"10.31557/apjcc.2023.8.2.275-279","DOIUrl":"https://doi.org/10.31557/apjcc.2023.8.2.275-279","url":null,"abstract":"Introduction: Research on various aspects of cancer, including stigma among cancer patients have received considerable interest in the recent years, but very few studies have studied cancer related stigma in healthy population. This study aimed to assess the situation of cancer stigma among the non-patient population.Methods: This cross-sectional study included 330 purposively selected non-patient population of age 18-45 years visiting B&B Hospital, Lalitpur, Nepal from March 2019 to August 2019. The data was collected from self-administered questionnaires. Caner stigma was measured with the validated Cancer Stigma Scale, which assesses six sub domains viz. severity, personal responsibility, awkwardness, avoidance, policy opposition and financial discrimination. Results: The highest score in Cancer Stigma Scale was found in the “severity”, while the lowest in the “policy opposition”. The policy opposition statements “More government funding should be spent on care and treatment of those with cancer” and “cancer patients should be given top priority” attracted the highest level of agreement (75.4 - 81.6%) followed by the statement about their comfort with cancer patients (59.5%), the acceptability for insurance companies to reconsider a policy once diagnosed with cancer (54.5%). A similar proportion felt getting cancer is to be prepared for death (38.5%) and a cancer patient is to be blamed for its condition (33.7%). Conclusions: Cancer stigma persists in Nepal with varying level in different domains of stigma.","PeriodicalId":436394,"journal":{"name":"Asian Pacific Journal of Cancer Care","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115200614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}