Khalij-Libya Journal of Dental and Medical Research最新文献

{"title":"Effect of Dimethoate Insecticide on Female Mice and Their Fetuses","authors":"Samira Sasi, N. Alghoul, Fauzia Mohamed, Zainab ELMabrouk, Habiba El Jaafari, Hanain Tunsi, Walid Saadawi, R. Prastiya","doi":"10.47705/kjdmr.248107","DOIUrl":"https://doi.org/10.47705/kjdmr.248107","url":null,"abstract":"Background and objectives. Organophosphate insecticides (OPIs) including dimethoate are used in agriculture to control the insect pests, increasing the productivity, their frequent use has resulted in detrimental effects on biological systems and public health. This study aimed to evaluate the effect of dimethoate (DM) on fetuses, DNA concentration in ovarian tissues and levels of estradiol and progesterone in female mice. Methods. Female mice were divided into three groups: Group I, serve as control and was given distilled water intraperitoneally, while Group II and III were given (0.1- & 0.2-ml DM/100 ml distilled water) respectively for 7 days. Two treated females were housed with one untreated male for mating. After 7 days of the last dose, 6 female mice of each group were weighed and killed. The ovaries, uteri and liver were extracted and weighed, and ovarian hormones were measured. Also, DNA concentration in each ovary was determined. Results. The results showed a significant decrease in the weights of the liver and ovaries, the level of estradiol hormone, and DNA concentration in the ovary of treated mice as compared to those from the control group. Also, significant changes were observed in the weights of fetuses as well as the number of live fetuses. Conclusion. We found that administration of DM intraperitoneally to female mice for 7 days has influences on ovary weight, estradiol levels, and DNA concentration as well as its impact on the fetuses, therefore, it is better to use safer methods for control the pests and avoid increased use of pesticides.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"9 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140261180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness Dental Specialists about Different Treatment Modalities to Replace Congenitally Missing Lateral Incisors","authors":"Aiman Elmabruk, Ahmed Mhanni, Hisham Shembesh, Abdulghani Alarabi","doi":"10.47705/kjdmr.248106","DOIUrl":"https://doi.org/10.47705/kjdmr.248106","url":null,"abstract":"Aims. The purpose of this study is to ascertain the dentists' and dental experts' knowledge of orthodontic closure vs. replacement as treatment options for congenitally missing lateral incisors. Methods. A cross-sectional study involving 185 dentists from several areas was carried out between September and October of 2023. A set of twenty-four multiple-choice questions was developed. Microsoft Excel 2010 was used for data collection, while SPSS version 26 was used for analysis utilising descriptive statistics and Chi-square tests. Results. A study of 185 questionnaires found that the majority of participants were general practitioners, with 56.6% working in private and government-funded clinics. Most participants exhibited an elevated incidence of lateral incisor tooth absence, a trend frequently identified through routine diagnostic procedures. A dentist with over ten years of experience identified a growing occurrence of lateral incisor tooth absence, calling for a specialised treatment approach. Participants generally preferred dental implants over orthodontics, fixed prostheses, and removable prostheses. Most general practitioners, oral surgeons, prosthodontists, and orthodontists preferred implant replacement for long-term aesthetic and functional results. The study found significantly those general practitioners and oral surgeons mostly stay updated on missing lateral incisor treatment through continuing education courses, while orthodontists and prosthodontists prefer reading professional journals. Conclusion. It is evident that the prevalence of tooth agenesis has increased, leading to a heightened demand for specialised dental treatment. Management of this anomaly requires comprehensive planning, considering self-consciousness, aesthetics, and malocclusion. The study emphasises the need for a multidisciplinary approach in the treatment of missing lateral incisors to ensure optimal outcomes.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"11 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermodynamics of Mitochondrial Aspartate Aminotransferases in the Presence of Nanoparticles","authors":"M. Abushhewa, Abdulati Salem, Abdusalam Mahmoud, Ramzi Mohsen","doi":"10.47705/kjdmr.237213","DOIUrl":"https://doi.org/10.47705/kjdmr.237213","url":null,"abstract":"Background and objectives. The nanoparticles are extensively used in the fields of biotechnology, the medical biochemistry and nanomedicne for enhancement and improvement drugs targeting in the chemotherapy. This study was conducted firstly, to understand the underlying mechanisms and potential applications of the thermo-inactivation kinetics of mitochondrial aspartate aminotransferase (mAspAT) in the presence of various nanoparticles, specifically TiO2 and Fe3O4, as well as gold nanoparticles (AuNP), secondly, to determine the impacts of nanoparticle concentration on the aggregation process and the influence the conformational stability and thermal behavior of mAspAT. Methods. The mAspAT was isolated from the pig heart, and SDS electrophoresis was used to determine the level of the protein's purity. A solution of native and modified dextran sulfate nanoparticles was prepared and incubated with mAspAT at various temperatures. The thermo-Inactivation was carried out at different temperatures (45, 50, 55, 60, 65, and 70 °C) and the aggregation of mAspAT was studied at 320 nm using spectrophotometry. The output data was manipulated (Calculations) and analyzed by Software Stadia 6.0. Results. TiO2 and Fe3O4 nanoparticles, both native and dextran sulfate-coated, demonstrated thermoprotective effects on mAspAT at temperatures above 60 °C. The interaction of mAspAT with TiO2 nanoparticles resulted in a decrease in thermoinactivation energy (Ea), indicating increased conformational stability. Therefore, constant thermoinactivation rate (kin) of mAspAT was significantly decreased in the presence of TiO2 nanoparticles. The dextran sulfate modification further enhanced this effect. Conclusion. The study concludes that the interaction of mAspAT with NP results in an increase in the conformation rigidity of the enzyme, which is primarily determined by the nature of NP and can be increased by coating the surface of NP with a polymer dextran sulfate. Also, Gold nanoparticles could potentially be used to increase the stability of mAspAT, preventing it from thermoaggregation.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":" 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138961929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prophylactic and Curative Effect of Boswellia Serrata on Blood Glucose Level and Architecture of Pancreas in Diabetic Mice Induced by Alloxan","authors":"","doi":"10.47705/kjdmr.237212","DOIUrl":"https://doi.org/10.47705/kjdmr.237212","url":null,"abstract":"Background and objectives. Herbal medicines have gained significant attention from the scientific community for treating and managing diabetes in both developing and developed countries. Boswellia serrata, known for its anti-inflammatory and antioxidant properties, has been historically used to treat various diseases. This study aimed to determine the effect of Boswellia serrata on body weight, blood glucose level, and pancreas architecture in alloxan-induced diabetes in albino mice. Methods. Forty albino male mice, aged 10 to 12 weeks and weighing between 24 and 34 grams, were divided into four groups of ten each. The first group was the negative control group, and the second group was the diabetic positive control group that received 120 mg/kg alloxan intraperitoneally. The third group received a single injection of alloxan at a dose of 120 mg/kg bw and was treated with Boswellia serrata macerated at a dose of 150 mg/kg bw for four weeks. The fourth group received orally Boswellia serrata extract at a dose of 150 mg/kg for two weeks, followed by a single injection of alloxan at a dose of 120 mg/kg, and were left for two weeks. Results. This study found that Boswellia serrata has antidiabetic properties in diabetic mice, as it significantly reduced blood sugar levels compared to the diabetic group. Additionally, histological analyses of the groups treated with B. serrata showed a significant improvement in the harmful effects of alloxan on pancreatic islet cells. Conclusion. Boswellia serrata has shown a notable improvement in the detrimental effect of alloxan on pancreatic islet cells, and its curative effect has been proven to be better than its prophylactic effect. This is supported by the improved blood glucose levels and the histological changes that were more pronounced.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"12 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138598586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of HIV Infection among Libyan Population in Tripoli-Libya","authors":"N. Elyounsi, Soomia Al-Haddad, Abdussalam Ashour, Ahmed Atia","doi":"10.47705/kjdmr.237209","DOIUrl":"https://doi.org/10.47705/kjdmr.237209","url":null,"abstract":"Objective. The study was conducted at the National Center for Diseases Control (NCDC), Tripoli Libya, aimed to assess the prevalence of human immune-deficiency viral infection (HIV). Methods. Data on HIV patients from the records of the NCDC from January 2019 to December 2021 were included. Enzyme-Linked Immunosorbent Essay were used to the viral detection. Data were analyzed using SPSS version 22. Results. Out of the total 3396 records, 624(18.37%) were tested HIV positive; of which 498(14.66%) were male and 3.71% were females. The majority of positive samples were linked to the ages of ≥ 40 years. Conclusion. HIV testing is important step for prevention, early diagnosis, and control prevalence of HIV. Educational and environmental interventions aimed to minimize the risk of HIV is important to uphold HIV control in country.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139315828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"http://journals.khalijedental.com.ly/index.php/ojs/article/view/55","authors":"Enas Khamakhim","doi":"10.47705/kjdmr.237202","DOIUrl":"https://doi.org/10.47705/kjdmr.237202","url":null,"abstract":"Background and objectives. Many dental practitioners have always struggled with obtaining aesthetic restorations while preserving the remaining dental structure. The purpose of this study is to investigate the relationship between the occlusal thickness and fracture resistance of CAD/CAM monolithic zirconia restorations to determine the feasibility of reducing the occlusal thickness, particularly in the posterior area, where inter-occlusal space is typically limited and high biting forces are applied. Methods. Four experimental groups were created using thirty-two CAD-CAM monolithic zirconia crowns with different occlusal thicknesses: 2.0 mm (group 1), 1.5 mm (group 2), 1.0 mm (group 3), and 0.5 mm (group 4). Self-adhesive resin cement was used to cement the restorations to human molars. Loading the specimens until fracture occurred, and the fracture resistance and mode of failure were recorded. The data were statistically analyzed using a one-way ANOVA followed by Fisher's exact test. Results. All specimens' fracture resistance values exceeded the maximum physiological occlusal loads in molar areas, and all of the crowns had consistent microcracks. A complete fracture was only interested in one crown with a thickness of 0.5 mm. Conclusion. The occlusal thickness of CAD-CAM monolithic zirconia crowns can be decreased to 0.5 mm while still being strong enough to sustain occlusal loads.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139370501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Gingival Bleeding Awareness Among Dental Students at University of Tripoli","authors":"Nadia Rahouma, Samira Buzinin, Kholoud Ftis","doi":"10.47705/kjdmr.237201","DOIUrl":"https://doi.org/10.47705/kjdmr.237201","url":null,"abstract":"Background and objectives. Bleeding of the gingiva is considered as an early sign of gingival inflammation and periodontal destruction. Bleeding on probing is used by clinicians to measure the prevalence and progression of periodontal disease, evaluate treatment outcome, and motivate patients to perform regular professional home care. The aims of this study were to assess self-experience gingival bleeding and to determine the oral health attitude and behavior among Libyan dental students. Methods. About 230 undergraduate dental students were given a questionnaire administered by three investigators after taking verbal consent. The answers of the filled questionnaires have been collected within 30 days and analyzed through SPSS version 25. Results. A total of 220 students answered the questionnaire and the frequency of gingival bleeding during tooth brushing were (55.0%) of students rarely experience gingival bleeding, twenty-nine participants (13.2%) frequently practiced gingival bleeding, and nearly one third (70, 31.8%) of students conveyed no bleeding. More than 72% of the students answered that smoking might increase gingival bleeding. Regarding mechanical stimuli, tooth brushing was considered by 77.7% of students as the main cause of gingival bleeding. Along with 18.7% have bleeding while eating hard food. Furthermore, only 3.6% of the study sample have early morning gingival bleeding. After bleeding, 33.2% of students visited the dentist whereas 23.6% of students stopped tooth brushing. Conclusions. Knowledge and awareness concerning cause of gingival bleeding is still poor among Libyan dental students. Furthermore, many responses of these students were inappropriate or not optimal regarding the management of the gingival bleeding. Therefore, more dental health education is needed to improve oral health and prevent periodontal disease.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122081344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Clinical Communication for Fixed Prosthodontics Construction between Dental Laboratories and Dentists","authors":"S. Elsawaay, Enas Khamakhim","doi":"10.47705/kjdmr.237107","DOIUrl":"https://doi.org/10.47705/kjdmr.237107","url":null,"abstract":"Objective. This study aimed to estimate the communication between dental practitioners and dental technicians, through fixed prosthodontics from a dental laboratory technician's point of view, study the weak points, and try to offer them. Methods. In Tripoli, a randomized sample of private dental laboratories was chosen. A hundred and fifty questionnaires were distributed, and 130 were received (response rate=87%). A part of the questionnaires was mailed to the laboratory directors of dental laboratories and others were distributed to the dental technicians personally (face to face). The survey asked questions about the following areas of work authorization: Academic certificate, Years of work as a dental clinician, choice of materials for the prosthesis, design of the fixed prosthesis, and shade description. The use of impression materials for fixed prosthodontics was part of the questionnaire. For each question, the number of responses received was tabulated and converted to a percentage. Data were collected and analyzed statistically with (SPSS) version 25 software and Pearson’s Chi-square test p value < 0.05 was considered as statistically significant. Results. The findings showed that the telephone 42.9% and written dental prescription 24.2% are the main communication tools. The technician is more likely to choose fixed prosthesis design alone when conversing with doctors verbally or via email, while they sometimes choose it when sending them written prescriptions. Therefore, the best form of cooperation would be a written prescription. 84.6% of dental technicians received impressions in a non-disinfected state. The plastic stock tray was the most common choice of impression tray (75.4%). The minority of dental technicians 19.7% are discussing pontics design with the dentist. Conclusion. According to Tripoli dental technicians, good quality communication between both dental technologists and dentists is not always present. The connection between these two dental offices still needs work.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"57 6 Suppl 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133350584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal Diseases Awareness and Knowledge Among Secondary School Teachers","authors":"","doi":"10.47705/kjdmr.237106","DOIUrl":"https://doi.org/10.47705/kjdmr.237106","url":null,"abstract":"Background and objectives. To determine level of knowledge related to etiology, risk factors, most common signs of periodontal diseases, knowledge related to oral hygiene practices, and relation between knowledge and oral hygiene practices among participants. Methods. 244 questionnaire answered by secondary school teachers consisted of a demographic data, and questions concerned knowledge regarding the causes of periodontal disease, its risk factors, and the most common signs of periodontal disease as well as the knowledge of periodontal diseases outcome and oral hygiene practice‑related questions. Results. Above half (54.5%) of respondents exhibited good knowledge on periodontal diseases etiology, predisposing factors and most common signs of periodontal diseases, (40.2%) of participants have positive awareness toward periodontal disease outcome, and (82.80%) of respondents have adequate behavior toward oral hygiene maintenance. Conclusions. Despite the participants have good knowledge on etiology of periodontal diseases and adequate behavior toward oral hygiene maintenance, they have deficient knowledge on hereditary, mouth breathing, stress, and obesity as predisposing factors of periodontal diseases and they have misbelief that removing the calculus accumulated on the teeth surfaces weaken the teeth.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130566561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation the Presence of Border Molding in Final Impression for Fabrication of Removable Prosthesis by General Practitioner in Tripoli, Libya","authors":"Sarra Ben Hamida","doi":"10.47705/kjdmr.237105","DOIUrl":"https://doi.org/10.47705/kjdmr.237105","url":null,"abstract":"Background and objectives. Cross infection among prosthodontologist and dental lab technicians is very important issue, especially after several studies found that transmission of infection to dental lab technicians is mainly by contaminated impressions or by improper handling of clinical items after arrival at the Dental laboratory. Dental impressions can be cross-contaminated by patient’s saliva and blood, which then cross-infect the dental casts poured from the impressions. The present study was carried out to evaluate the knowledge and the practice of infection control of dental impressions among dental technicians in Tripoli, Libya. Methods. This study was based on questionnaire that designed to cover different aspects of cross-infection control in the dental clinic. The questionnaire consists of 10 closed end question and 3 yes, no question. Results. The response rate was 85%. The questionnaire showed that almost 32.9% of the dental technicians did not have instructions related to disinfection in the dental lab. Upon receipt of dental impressions, the majority (80.5%) reported always rinsing them with water only. Moreover, about 7.8% of the dental technicians reported never disinfecting dental impressions and about 16.9% reported that they sometimes disinfected impressions. In the labs were the disinfection applied, 12% of the dental labs used spray disinfection (without water) and also 12% of dental technicians used immersion disinfection (without water). Conclusion. The findings of this study show that practices and awareness of dental technicians regarding infection control are less than ideal, moreover there is lack of communication between dentists and dental technicians so should increase awareness and establishing educational programs for both dentists and dental technicians to decrease the risk of transmission of diseases in dental laboratories.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132944601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}