Nutrition and Dietary Supplements最新文献

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Supplemental Nutrition Assistance Program (SNAP): does receiving assistance impact food choices? 补充营养援助计划(SNAP):接受援助会影响食物选择吗?
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2019-08-01 DOI: 10.2147/NDS.S177809
Prageet K. Sachdev, Mahsa Babaei, J. Freeland-Graves
{"title":"Supplemental Nutrition Assistance Program (SNAP): does receiving assistance impact food choices?","authors":"Prageet K. Sachdev, Mahsa Babaei, J. Freeland-Graves","doi":"10.2147/NDS.S177809","DOIUrl":"https://doi.org/10.2147/NDS.S177809","url":null,"abstract":": The Supplemental Nutrition Assistance Program (SNAP) is the largest federal program that provides assistance for the purchase of foods to low-income households in the United States. SNAP plays a valuable role in alleviating hunger and food insecurity in poor households; however, one consideration that remains relatively unexplored is the in fl uence of this program on food choices. Food choices are guided by several factors in low-income individuals, including the cost of food, household size, nutrition knowledge, availability of fresh foods in the neighborhood, transportation, and cultural factors. Also, the complex relationship between SNAP participation and food choices is further confounded by the factors of demographics, food insecurity, poverty, and self-selection. There is a lack of quantitative investigations that directly evaluate food choices in SNAP recipients. As a result, this review will focus on summarizing fi nding from studies that assessed food purchasing patterns, diet quality, and weight gain in SNAP participants. These outcomes may serve as proxy measures to evaluate the food choices made by SNAP participants. In addition, this review discusses many behavioral economic strategies such as reducing the cost of healthy foods, providing monetary bene fi ts for purchase of healthy foods, increasing the SNAP bene fi ts, incentivizing small food retailers to offer more food choices in low-income neighborhoods, increasing grocery stores and supermarkets in poor neighborhood, and strengthening the SNAP-Ed program; some of which have been previously adopted to promote the selection of healthy foods in SNAP participants. SNAP has the potential to impact food choices in the society, as such longitudinal studies are needed to evaluate the effectiveness of any reforms in SNAP bene fi ts or restrictions, which may seem logical but not impact food choices in reality.","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S177809","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46383622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Nutrition in sickle cell disease: recent insights 镰状细胞病的营养:最近的见解
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2019-05-23 DOI: 10.2147/NDS.S168257
K. Umeakunne, J. Hibbert
{"title":"Nutrition in sickle cell disease: recent insights","authors":"K. Umeakunne, J. Hibbert","doi":"10.2147/NDS.S168257","DOIUrl":"https://doi.org/10.2147/NDS.S168257","url":null,"abstract":"Point your SmartPhone at the code above. If you have a QR code reader the video abstract will appear. Or use: https://youtu.be/reuY48oNE-w Abstract: A cure for sickle cell anemia (SCA) is not available to all who have inherited this devastating genetically inherited disease. However, increasing knowledge that nutritional problems are fundamental to the severity of the disease, has produced interest in promoting dietary supplementation for treating these patients. This review seeks to emphasize the understanding that both children and adults with sickle cell disease require much higher energy and protein consumption (more macronutrient intake) than healthy individuals and tend to suffer from undernutrition if energy intake is consistently low. Shortages may also exist for micronutrients, eg, Glutathione, which has both anti-inflammatory and anti-oxidant properties. Both chronic inflammation and oxidant stress are central issues for increased sickle cell disease severity. In conclusion, dedicating more effort and resources to establishing recommended dietary reference intakes (DRIs)/recommended dietary allowances (RDAs) for SCA patients is essential, and nutritional intervention should be included as an adjunct treatment in tandem with standard practice.","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2019-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S168257","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48728323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Dietary diversity and associated factors among pregnant women attending antenatal care at public health facilities in Bale Zone, Southeast Ethiopia 在埃塞俄比亚东南部贝尔区公共卫生机构接受产前护理的孕妇的饮食多样性及其相关因素
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2019-04-05 DOI: 10.2147/NDS.S179265
Sintayehu Hailu, Bedasa Woldemichael
{"title":"Dietary diversity and associated factors among pregnant women attending antenatal care at public health facilities in Bale Zone, Southeast Ethiopia","authors":"Sintayehu Hailu, Bedasa Woldemichael","doi":"10.2147/NDS.S179265","DOIUrl":"https://doi.org/10.2147/NDS.S179265","url":null,"abstract":"","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2019-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S179265","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48359372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Assessing the impact of nutrition interventions on health and nutrition outcomes of community-dwelling adults: a systematic review 评估营养干预对社区居住成年人健康和营养结果的影响:一项系统综述
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2018-11-01 DOI: 10.2147/NDS.S177248
A. Sauer, Jian Li, J. Partridge, S. Sulo
{"title":"Assessing the impact of nutrition interventions on health and nutrition outcomes of community-dwelling adults: a systematic review","authors":"A. Sauer, Jian Li, J. Partridge, S. Sulo","doi":"10.2147/NDS.S177248","DOIUrl":"https://doi.org/10.2147/NDS.S177248","url":null,"abstract":"Background: Malnutrition is pervasive in hospitalized patients and older adults. Although evidence shows the benefits of nutrition interventions in hospitalized patients, less is known about the role these interventions play on outcomes in patients in the community. Objective: The objective of this systematic review is to evaluate the current evidence on nutrition interventions’ impact on health and nutrition outcomes among community-dwelling adults. Methods: This systematic review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Original studies of previously published research were identified by using a predefined search strategy. Articles identified through electronic and manual searches were compared against predefined study selection criteria. Results: Twenty articles were deemed eligible for inclusion. Most of the studies examined nutrition interventions through oral nutritional supplements, dietary advice, counseling, and home visits, and were conducted in subjects who either had or were at risk of malnutrition. Nutrition interventions were found to improve anthropometrics (body weight), nutritional and functional status, energy and protein intake, and muscle strength (handgrip strength). However, their impact was inconclusive for body composition, quality of life, readmissions, complications/morbidity, and mortality, mainly due to a limited number of studies. Conclusion: Nutrition interventions were found to improve health and nutrition outcomes among community-dwelling adults. Future research is needed to examine the pervasiveness of malnutrition in the community, to evaluate the impact that nutrition interventions have on improving health outcomes in this population, and to inform the design of novel nutrition-focused intervention programs for adults living in different community settings to improve outcomes.","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S177248","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47741092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Current perspectives of caffeinated energy drinks on exercise performance and safety assessment 含咖啡因能量饮料对运动表现和安全性评估的当前观点
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2018-07-01 DOI: 10.2147/NDS.S143147
R. Kreider
{"title":"Current perspectives of caffeinated energy drinks on exercise performance and safety assessment","authors":"R. Kreider","doi":"10.2147/NDS.S143147","DOIUrl":"https://doi.org/10.2147/NDS.S143147","url":null,"abstract":": Energy drinks and energy shots have become very popular among athletes and the general population. They typically contain carbohydrate, caffeine, and other nutrients purported to enhance mental and/or physical performance. Additionally, several caffeine-containing pre-workout supplements have been developed which are commonly consumed as a drink prior to and/or during exercise. While occasional ingestion of these types of products appears to be safe and may offer some ergogenic benefit, individuals who consume these products indiscriminately need to be careful and consider how ingestion of these products may affect the total daily intake of caffeine and other stimulants throughout the day, to minimize any adverse events and/or harmful side effects. This review provides an update as to the current literature on energy drinks and energy shots and provides practical recommendations for their appropriate use among athletes.","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":"1 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S143147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44622380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
The gluten-free diet: access and economic aspects and impact on lifestyle 无谷蛋白饮食:获取和经济方面以及对生活方式的影响
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2018-06-01 DOI: 10.2147/NDS.S143404
Mayra Arias-Gastélum, F. Cabrera-Chávez, M. Vergara-Jiménez, N. Ontiveros
{"title":"The gluten-free diet: access and economic aspects and impact on lifestyle","authors":"Mayra Arias-Gastélum, F. Cabrera-Chávez, M. Vergara-Jiménez, N. Ontiveros","doi":"10.2147/NDS.S143404","DOIUrl":"https://doi.org/10.2147/NDS.S143404","url":null,"abstract":"Background: The cost and availability of gluten-free products (GFPs) are aspects associated with gluten-free dietary compliance. In turn, following a gluten-free diet (GFD) could impact on lifestyle. Objectives: To investigate the availability and cost of GFPs in Northwestern Mexico, to associate these factors with gluten-free dietary noncompliance, and to evaluate the impact of the GFD on lifestyle. Materials and methods: Gluten-containing foods were compared with their gluten-free versions. The data were collected by store visitation (16 supermarkets and 10 health food stores). Individuals prescribed a GFD by a physician were surveyed (n = 36). Results: The gluten-free versions investigated (n = 16) had limited availability (average 26.9%; 4.3 gluten-free versions available per store) and were more expensive than their gluten-containing counterparts (190%–1088%, P < 0.05). Poor gluten-free dietary compliance was attributed to the high cost (n = 36) and low availability (n = 30) of GFPs. Most respondents were afraid of dining out (n = 35), were limiting their social activities (n = 32), and had difficulties traveling (n = 30). Conclusion: Health care professionals who counsel gluten-sensitive patients should provide tools to facilitate access to GFPs and to minimize the cost of the GFD, and consider the diet-associated social restrictions.","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S143404","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47877675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana. 博茨瓦纳艾滋病毒感染早期微量营养素补充对活动性肺结核发病率的影响。
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2017-01-01 Epub Date: 2017-07-14 DOI: 10.2147/NDS.S123545
Adriana Campa, Marianna K Baum, Hermann Bussmann, Sabrina Sales Martinez, Mansour Farahani, Erik van Widenfelt, Sikhulile Moyo, Joseph Makhema, Max Essex, Richard Marlink
{"title":"The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana.","authors":"Adriana Campa, Marianna K Baum, Hermann Bussmann, Sabrina Sales Martinez, Mansour Farahani, Erik van Widenfelt, Sikhulile Moyo, Joseph Makhema, Max Essex, Richard Marlink","doi":"10.2147/NDS.S123545","DOIUrl":"10.2147/NDS.S123545","url":null,"abstract":"<p><strong>Background: </strong>Coinfection with active tuberculosis (TB) is one of the leading causes of death in people living with HIV (PLWH) in Africa. This investigation explores the role of micronutrient supplementation in preventing active TB in PLWH.</p><p><strong>Methods: </strong>A randomized trial of nutritional supplementation was conducted among antiretroviral- naïve (without previous antiretroviral treatment [ART]) HIV-infected people in Botswana between 2004 and 2009. The study had a factorial design with four arms: the selenium (Se) alone arm, the multivitamins (MVT) alone arm that contained vitamin B complex and vitamins C and E, the combined Se+MVT group and the placebo group. Those participants with prior or current active TB were excluded, as were participants with advanced HIV disease (CD4 <250 cells/μL) or who had already qualified for ART. HIV-positive adults (N=878) were followed monthly for study pill dispensation, every 3 months for CD4 cell count and every 6 months for viral load during 24 months or until they were started on ART.</p><p><strong>Results: </strong>The participants' characteristics were not significantly different among the four groups at baseline. Supplementation with Se alone (hazard ratio =0.20, 95% confidence interval: 0.04, 0.95, <i>P</i>=0.043) and the two combined SE groups (Se and Se+MVT) had significantly lower risk of developing incident TB disease compared with placebo in multivariate adjusted models (hazard ratio=0.32, 95% confidence interval: 0.11, 0.93, <i>P</i>=0.036). Multivitamins alone did not affect the incidence of TB. Isoniazid preventive therapy was received by 12.2% of participants, a rate that was not significantly different among the four study arms (<i>P</i>=0.122) and the newly diagnosed cases.</p><p><strong>Conclusion: </strong>Se supplementation, alone and with MVT, decreased the incidence of TB disease in PLWH who were ART-naïve. Supplementation with these micronutrients should be considered in HIV infection, prior to ART, in areas where TB and malnutrition are endemic.</p>","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":"2017 9","pages":"37-45"},"PeriodicalIF":1.5,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cf/34/nihms893644.PMC5703420.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35207219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Taurine and vitamin E supplementations have minimal effects on body composition, hepatic lipids, and blood hormone and metabolite concentrations in healthy Sprague Dawley rats. 补充牛磺酸和维生素E对健康大鼠的身体组成、肝脏脂质、血液激素和代谢物浓度的影响很小。
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2015-10-20 DOI: 10.2147/NDS.S88888
P. Allen, A. Brown, M. Brown, W. Hsu, D. Beitz
{"title":"Taurine and vitamin E supplementations have minimal effects on body composition, hepatic lipids, and blood hormone and metabolite concentrations in healthy Sprague Dawley rats.","authors":"P. Allen, A. Brown, M. Brown, W. Hsu, D. Beitz","doi":"10.2147/NDS.S88888","DOIUrl":"https://doi.org/10.2147/NDS.S88888","url":null,"abstract":"BACKGROUND\u0000As prescriptions for off-label pharmaceutical use and autonomous administration of over-the-counter nutraceuticals become mainstream, thorough assessments of these compounds are warranted.\u0000\u0000\u0000OBJECTIVE\u0000To determine the effects of gemfibrozil, rosiglitazone, metformin, taurine, and vitamin E on body composition, hepatic lipids, and metabolic hormone and blood metabolite concentrations in a healthy, outbred rat cohort.\u0000\u0000\u0000METHODS\u0000Male Sprague Dawley rats were fed a purified 10 kcal% from fat diet for 56 days and assigned to diet alone (control) or diet plus oral administration of gemfibrozil (34 mg/kg), metformin (500 mg/kg), rosiglitazone (3 mg/kg), taurine (520 mg/kg), or vitamin E (200 mg/kg).\u0000\u0000\u0000RESULTS\u0000Rosiglitazone administration resulted in a 56% increase in carcass adiposity, cautioning potential prescriptive off-label use. Taurine supplementation had no adverse effects on evaluated parameters. A modest but significant increase in liver triacylglycerol content was observed with vitamin E supplementation compared with control (Δ 17.2 g triacylglycerol/100 g liver lipid).\u0000\u0000\u0000CONCLUSIONS\u0000The evaluated pharmaceuticals had effects in a healthy population similar to the reported effects in their target population and the nutraceuticals had minimal effects on the measured physiological parameters.","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":"7 1","pages":"77-85"},"PeriodicalIF":1.5,"publicationDate":"2015-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S88888","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68394784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Intrinsic association between diet and the gut microbiome: current evidence. 饮食和肠道微生物群之间的内在联系:目前的证据。
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2015-01-01 Epub Date: 2015-10-07 DOI: 10.2147/NDS.S62362
Kathryn Winglee, Anthony A Fodor
{"title":"Intrinsic association between diet and the gut microbiome: current evidence.","authors":"Kathryn Winglee,&nbsp;Anthony A Fodor","doi":"10.2147/NDS.S62362","DOIUrl":"https://doi.org/10.2147/NDS.S62362","url":null,"abstract":"<p><p>The gut microbiome performs many crucial functions for the human host, but the molecular mechanisms by which host, microbe and diet interact to mediate health and disease are only starting to be revealed. Here we review the literature on how changes in the diet affect the microbiome. A number of studies have shown that within a geographic region, different diets (such as vegan vs. omnivore) are associated with differences in a modest number of taxa but do not reliably produce radical differences within the gut microbial community. In contrast, studies that look across continents consistently find profoundly different microbial communities between Westernized and traditional populations, although it remains unclear to what extent diet or other differences in lifestyle drive these distinct microbial community structures. Furthermore, studies that place subjects on controlled short term experimental diets have found the resulting alterations to the gut microbial community to generally be small in scope, with changes that do not overcome initial individual differences in microbial community structure. These results emphasize that the human gut microbial community is relatively stable over time. In contrast, short term changes in diet can cause large changes in metabolite profiles, including metabolites processed by the gut microbial community. These results suggest that commensal gut microbes have a great deal of genetic plasticity and can activate different metabolic pathways independent of changes to microbial community composition. Thus, future studies of the how diet impacts host health via the microbiome may wish to focus on functional assays such as transcriptomics and metabolomics, in addition to 16S rRNA and whole-genome metagenome shotgun analyses of DNA. Taken together, the literature is most consistent with a model in which the composition of the adult gut microbial community undergoes modest compositional changes in response to altered diet but can nonetheless respond very rapidly to dietary changes via up- or down-regulation of metabolic pathways that can have profound and immediate consequences for host health.</p>","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":"7 ","pages":"69-76"},"PeriodicalIF":1.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/NDS.S62362","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35153325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A review of gluten- and casein-free diets for treatment of autism: 2005-2015. 2005-2015 年治疗自闭症的无麸质和无酪蛋白饮食回顾。
IF 1.5
Nutrition and Dietary Supplements Pub Date : 2015-01-01 Epub Date: 2015-12-01 DOI: 10.2147/NDS.S74718
Jennifer Harrison Elder, Consuelo Maun Kreider, Nancy M Schaefer, Mary B de Laosa
{"title":"A review of gluten- and casein-free diets for treatment of autism: 2005-2015.","authors":"Jennifer Harrison Elder, Consuelo Maun Kreider, Nancy M Schaefer, Mary B de Laosa","doi":"10.2147/NDS.S74718","DOIUrl":"10.2147/NDS.S74718","url":null,"abstract":"<p><strong>Background: </strong>The gluten free, casein free (GFCF) diet is heralded by strong anecdotal parental reports to greatly improve and even \"cure\" symptoms of Autism Spectrum Disorders (ASD). Yet to date, little conclusive empirical evidence exists supporting its use.</p><p><strong>Objective: </strong>The purpose of this paper is to provide an overview of the state of the recent evidence regarding use of GFCF diet for treatment of individuals with ASD.</p><p><strong>Methods: </strong>Five database providers (PubMed, Web of Knowledge, EBSCO, ProQuest, and WorldCat) were used to search 19 databases yielding a total of 491 articles that were published through February 2015. Peer reviewed articles published between 2005 and February 2015 were included for review if study participants were identified as having ASD and investigated the effects of the GFCF diet on ASD behaviors or the relationship between the diet and these behaviors.</p><p><strong>Results: </strong>Evaluation of search results yielded 11 reviews, 7 group experimental studies including 5 randomized controlled trials, 5 case reports, and 4 group observational studies published during the last 10 years. These studies represent a marked increase in number of reported studies as well as increased scientific rigor in investigation of GFCF diets in ASD.</p><p><strong>Conclusions: </strong>While strong empirical support for the GFCF diet in ASD is currently lacking, studies point to the need for identifying subsets of individuals (e.g., those with documented gastrointestinal abnormalities) who may be the best responders to the GFCF diet. Identifying these subsets is critically needed to enhance rigor in this research area. Until rigorous research supporting use of GFCF diet is reported, clinicians should continue use caution and consider several factors when advising regarding implementation of the GFCF diet for individuals with ASD.</p>","PeriodicalId":43423,"journal":{"name":"Nutrition and Dietary Supplements","volume":"7 1","pages":"87-101"},"PeriodicalIF":1.5,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68395083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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