{"title":"Major Drivers for COVID-19 Vaccine Acceptance: A Scoping Review","authors":"A. A. Al-Jumaili, Ali H. Hamzah","doi":"10.54133/ajms.v2i.59","DOIUrl":"https://doi.org/10.54133/ajms.v2i.59","url":null,"abstract":"Objective: To review and identify the major drivers for COVID-19 vaccine acceptance. Methods: A scoping review of studies of COVID-19 vaccine perceptions and barriers to using the COVID-19 vaccines. Two search engines, including PubMed and Google Scholar, were purposefully searched. Results: Eight studies from different countries were reviewed to categorize factors influencing people's acceptance of COVID-19 according to the Health Belief Model (HBM). Perceived susceptibility, and severity of the disease (COVID-19), in addition to perceived benefits of COVID-19 vaccination and \"cues to action\", can enhance vaccination acceptance. In contrast, perceived barriers to the COVID-19 vaccine can increase people's hesitancy to be vaccinated. Conclusions: The HBM domains are successful in the prediction of human behaviors toward preventive measures, including vaccination. In general, high perceived susceptibility, severity, benefits, and minimum barriers should always be maintained to keep the vaccination rate high. Reducing the hesitancy to get the vaccine can be achieved by increasing awareness campaigns about the vaccine's efficacy in preventing infection.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128226631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consequences of Restricting Tramadol Dispensing in Iraqi Private Healthcare Facilities","authors":"S. S. Mohammed, W. Mustafa, Manal Mohammed Younis","doi":"10.54133/ajms.v2i.58","DOIUrl":"https://doi.org/10.54133/ajms.v2i.58","url":null,"abstract":"Background and aim: Tramadol is a codeine analogue with less analgesic power than morphine but with better abuse potential. However, chronic use is associated with different adverse effects like anxiety, euphoria, nervousness, insomnia, depression, and agitation. In this study, we assessed the outcome behind the restriction on dispensing Tramadol in private health sectors in Iraq. Methods: We look at tramadol data from VigiBase data searches and the Individual Case Safety Reports (ICSR) that are formally supported by the WHO worldwide database. All complaints were evaluated using Vigilyze data mining and computing IC25 to assess the strength of the link between Tramadol and the adverse reactions it causes, as well as to compare them to other records from around the world. Results: For patients who used tramadol in a variety of dose forms, 184 instances were gathered over the course of seven years by the Iraqi Pharmacovigilance Center. There were 32 cases of hyperhidrosis, which occurred when tramadol was used alone, 47 incidents of vomiting, and 67 cases of nausea. Many adverse effects, including chest pain, hyperhidrosis, headache, dyspnea, and constipation, are more common in Iraqi records than in internationally known instances. Other side effects, such as vomiting, hallucination, vertigo, respiratory depression, and chills, were found to be milder than previously reported. There were no deaths in any of the instances that were recorded during this time period. Conclusion: The number of reported tramadol-induced adverse events has fallen significantly, which can be attributed to the ministry of health restricting tramadol dispensing and enabling public hospitals to only dispense it under medical monitoring.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116865835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nurses on the Front Lines Confronting COVID-19 Pandemic","authors":"Ahmed Lateef Alkhaqani","doi":"10.54133/ajms.v2i.60","DOIUrl":"https://doi.org/10.54133/ajms.v2i.60","url":null,"abstract":"Nurses worldwide face major health care problems, such as high patient mortality, high health care demands, a reduction in health care supplies, and extraordinary physical and emotional stress. First-line health and nurses working in Intensive Care Units (ICUs) played a significant role in responding to patients with COVID-19 globally. The COVID-19 epidemic marks a world public health crisis that has not been seen in the past century and has spread rapidly worldwide and the associated mortality burden. Health workers worldwide are responding to the demand for treatment of patients with COVID-19, which may result in high costs to their health and well-being. It is increasingly recognized that COVID-19 may affect the mental health of front-line workers, and it calls for psychological and social support. However, little attention has been paid to understanding the impact of working on a pandemic from healthcare workers’ perspectives or their views about support.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"320 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132301599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expression of NF-κB mRNA in Helicobacter pylori Positive Iraqi Patients with Inflammatory Bowel Diseases and Colorectal Cancer","authors":"S. Farhan","doi":"10.54133/ajms.v2i.57","DOIUrl":"https://doi.org/10.54133/ajms.v2i.57","url":null,"abstract":"Background: Inflammatory bowel diseases (IBD) and colorectal cancer (CRC) are caused by a combination of variables, including environmental, host-related, and nutritional factors. Helicobacter pylori (H. pylori) is an environmental risk factor for many GIT disorders and is designated as a class I carcinogen. Aim: To investigate the prevalence of H. pylori in Iraqi patients diagnosed with IBD and CRC and the expression of NF-κB mRNA in those patients. Methods: Patients with GIT symptoms were tested for the existence of IBD and CRC in a cross-sectional observational study. In biopsies taken from GIT lesions, biochemical and histochemical approaches are employed to determine the presence of H. pylori and the expression of NF-κB mRNA. Results: H. pylori tests were positive in 33.3% of CRC patients, although this was not statistically significant compared to those who had negative testing. Only 63.3% of IBD patients had H. pylori infection. In the CRC group, 53.3% of patients had negative NF-κB expression, whereas all of the patients in the IBD group had a negative test. Conclusion: Patients with CRC had a high prevalence of H. pylori, whereas IBD patients had a low frequency. Patients with CRC had high levels of NF-κB mRNA expression, whereas patients with IBS had none.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133886208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Shanshal, S. Hussain, A. M. Mahmood, Fatima Abood Zukhair, Ali Sabah Mahdi, Athraa Mohammad Mahmood, Nabaa Mustafa Hamed
{"title":"Exam-Related Anxiety Levels among Iraqi Medical Students in Baghdad City","authors":"A. Shanshal, S. Hussain, A. M. Mahmood, Fatima Abood Zukhair, Ali Sabah Mahdi, Athraa Mohammad Mahmood, Nabaa Mustafa Hamed","doi":"10.54133/ajms.v2i.56","DOIUrl":"https://doi.org/10.54133/ajms.v2i.56","url":null,"abstract":"Background: Exam-related anxiety is a set of responses that include excessive worry, depression, nervousness, and irrelevant thinking from an individual's experience of assessment or testing and its outcome. Aim: This study was designed to evaluate exam-related anxiety among medical students in Baghdad City. Methods: This study utilized a cross-sectional survey design and was conducted by administering an online questionnaire to medical students (medicine, dentistry, and pharmacy). Results: A total of 530 students participated in the survey; 20.8% of them came from medical colleges, 41.7% from dentistry schools, and 37.5% from pharmacy schools. Around 27.1% of the respondents reported positive test-related anxiety. Conclusion: Exam-related anxiety is frequent among Iraqi medical students in Baghdad and highlights the need for education programs to reduce this anxiety.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133828068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Biomarkers and Use of Herbal Products in Gastric Injury","authors":"Renas Raouf Hama Amin, B. Marouf","doi":"10.54133/ajms.v2i.54","DOIUrl":"https://doi.org/10.54133/ajms.v2i.54","url":null,"abstract":"An ulcer in the stomach is a common digestive system ailment. Gastric ulcers are more likely to develop if one drinks alcohol regularly. Despite the extensive availability of treatment options, there are just a few preventative regimes. In animal trials, herbal remedies have been found to prevent the formation of ethanol-induced stomach ulcers. Histamine receptor 2 antagonists have a similar or higher ability to inhibit the formation of ethanol-induced stomach ulcers to herbal treatments. There are less adverse effects associated with herbal remedies. PubMed, Google Scholar, and Web of Science databases were searched using keywords such as \"gastric ulcer,\" \"herbal medicines,\" and \"ethanol-induced gastric injury.\" The search was performed up to May 15, 2021. Only articles published in English were used in this review. For those who are more susceptible to develop stomach ulcers, certain herbal combinations may be an effective option to prevent the development of gastric ulcers, based on their methods of action and the pathogenesis of gastric ulcers. Dates, pomegranate seeds, and bitter melon are all examples of herbal compounds that are safe and can be ingested. Those who regularly use alcohol may want to consider using these substances as an alternative method of preventing stomach ulcers. Anti- Helicobactor pylori herbal components such as Mitrella kentia, citrus lemon, and Cratoxylum arborescens (Vahl) Blume can be used by Helicobacter pylori-positive individuals to avoid the creation of ethanol-induced stomach ulcers.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124936827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Vitamin D Deficiency on the Pathogenesis of Polycystic Ovary Syndrome","authors":"Noor Majid Raheem, Bushra Hassan Marouf","doi":"10.54133/ajms.v2i.53","DOIUrl":"https://doi.org/10.54133/ajms.v2i.53","url":null,"abstract":"There are many metabolic and hormonal factors related to polycystic ovary syndrome (PCOS) that can be affected by vitamin D3 supplementation. To find clinical trials, in vivo studies, and in vitro studies that met the review's inclusion and exclusion criteria, we searched many databases. PCOS women's ovulation and metabolic parameters were examined in relation to the effects of vitamin D3 treatment on PCOS risk variables such as seasonal changes in body mass index, and obesity. The current review included twenty-five articles. Vitamin D3(25-hydroxy vitamin D) levels were significantly lower in the PCOS group than in the control group, and lipid profile and androgen hormone levels were significantly higher in the PCOS group, resulting in increased cardiovascular events and exaggerated hirsutism. According to the majority of research, vitamin D3 plays a beneficial role in decreasing the pathophysiology of PCOS, notably in restoring ovulation, which ultimately improves fertility. Although other studies found no effect on lipid profile, there was a minor effect on reducing cardiovascular risks. The response of patients to vitamin D3 was influenced by the dose administered and the study's methodology. In conclusion, vitamin D3 had a good effect on the pathophysiology of PCOS in the majority of investigations.\u0000 ","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132860363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between Lipid Profile and Glycemic Status in Iraqi patients with Acromegaly Receiving Depot Long-Acting Octreotide","authors":"Omar Mohammed Al-Juboori","doi":"10.54133/ajms.v1i.48","DOIUrl":"https://doi.org/10.54133/ajms.v1i.48","url":null,"abstract":"Background: Treatment modalities of acromegaly and disease control impact differently on glucose homeostasis and lipid changes, and consequently on cardiometabolic risk. Aim: To investigate the possible association of lipid profile changes with the glycemic control status in acromegaly patients treated with octreotide LAR. Methods: This cross-sectional study included 52 Iraqi patients with acromegaly treated with octreotide LAR and not using statins. Demographic, anthropometric, and clinical data were collected, as well as the duration of Octreotide LAR administration. The glycemic state was assessed and classified as DM, prediabetes, or normal. Plasma levels of triglycerides, LDL cholesterol, HDL cholesterol, and non-HDL were evaluated using standard methods. Results: Most of the participants presented with low levels of triglycerides, LDL cholesterol, and HDL cholesterol. The lipid profile variables were not significantly correlated with the glycemic control status after treatment with octreotide LAR. Conclusion: Lipid profile parameters were not associated with the different glycemic control status of acromegaly patients treated with octreotide LAR.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128834527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Glycemic Status in Acromegaly Patients Receiving Depot Long-Acting Octreotide","authors":"Omar Al-Juboori, K. I. Al-Lehibi","doi":"10.54133/ajms.v1i.46","DOIUrl":"https://doi.org/10.54133/ajms.v1i.46","url":null,"abstract":"Background: Acromegaly is an uncommon, chronic, debilitating condition characterized by hyperinsulinism, insulin resistance, diabetes and prediabetes. One possibility for managing acromegaly's questionable influence on glucose homeostasis is the somatostatin analogues. Aim: To analyze the frequency and risk factors for impaired glucose homeostasis in acromegaly patients treated with depot long-acting octreotide (octreotide LAR), as well as the relationship between risk and treatment duration. Methods: The study included 52 Iraqi adults with acromegaly receiving octreotide LAR. Demographic, anthropometric, and clinical data were collected, as well as the duration of Octreotide LAR administration. Growth hormone, IGF-1, and adenoma size were reported retrospectively from patient data. The glycemic state was assessed and classified as DM, prediabetes, or normal. Results: The prevalence of DM was 39% and prediabetes was 40%, with the exception of being male, which was substantially related with prediabetes. DM and octreotide LAR use had a non-significant correlation. However, octreotide use altered 13% of patients from normal glycemic to prediabetes, with no correlation to treatment duration. Other than hypertension and a family history of diabetes, no other variables were found to be significant. Conclusion: Acromegaly patients have abnormal glucose metabolism, which is associated with prediabetes owing to octreotide LAR medication. Hypertension and family history of diabetes are risk factors.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"238 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116179984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 variants, available treatments, and vaccinations: An overview study","authors":"A. H. Mohammed, Azyyati Mohd Suhaimi, B. Hassan","doi":"10.54133/ajms.v1i.42","DOIUrl":"https://doi.org/10.54133/ajms.v1i.42","url":null,"abstract":"SARS-CoV-2 is the recent variation of the corona virus which is infecting people around the world and has affected more than 258 million people worldwide. Upon observation, the virus is similar to the coronavirus which spread from the horseshoe bat or wild animals to human beings. Up to date, there have been three major variants of the coronavirus which have been identified in UK, South Africa, and India which are spreading to other countries. Based on the current data, it is suggested that the incidents of repeated infection with SARS-CoV-2 is related to the level of neutralizing antibodies and the retained memory response which follows infection. Moreover, recently, a critical issue arises in relation to the association of black fungus and COVID-19, and urgent investigation is required. As a treatment method of COVID-19, FDA has recently approved the feasibility of Remdesivir to treat COVID-19 as emergency use authorization (EUA). There are also various possible antivirals which are still undergoing clinical trial. After widespread of the vaccine, the results showed that EUA vaccines have been effective in controlling COVID-19 in patients. However, these licensed vaccines ought to be reviewed to ensure they are also effective in combating the rising variants of SARS-CoV-2.","PeriodicalId":433524,"journal":{"name":"Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 )","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114616865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}