COVID-19 variants, available treatments, and vaccinations: An overview study

A. H. Mohammed, Azyyati Mohd Suhaimi, B. Hassan
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Abstract

SARS-CoV-2 is the recent variation of the corona virus which is infecting people around the world and has affected more than 258 million people worldwide. Upon observation, the virus is similar to the coronavirus which spread from the horseshoe bat or wild animals to human beings. Up to date, there have been three major variants of the coronavirus which have been identified in UK, South Africa, and India which are spreading to other countries. Based on the current data, it is suggested that the incidents of repeated infection with SARS-CoV-2 is related to the level of neutralizing antibodies and the retained memory response which follows infection. Moreover, recently, a critical issue arises in relation to the association of black fungus and COVID-19, and urgent investigation is required. As a treatment method of COVID-19, FDA has recently approved the feasibility of Remdesivir to treat COVID-19 as emergency use authorization (EUA). There are also various possible antivirals which are still undergoing clinical trial. After widespread of the vaccine, the results showed that EUA vaccines have been effective in controlling COVID-19 in patients. However, these licensed vaccines ought to be reviewed to ensure they are also effective in combating the rising variants of SARS-CoV-2.
COVID-19变异、可用治疗和疫苗接种:一项综述研究
SARS-CoV-2是冠状病毒的最新变种,它正在感染世界各地的人,全球已有2.58亿多人受到影响。经观察,该病毒与从马蹄蝠或野生动物传播给人类的冠状病毒相似。到目前为止,已经在英国、南非和印度发现了三种主要的冠状病毒变种,并正在传播到其他国家。根据目前的数据,我们认为重复感染SARS-CoV-2的事件与中和抗体水平和感染后保留的记忆反应有关。最近,黑木耳与新型冠状病毒感染症(COVID-19)之间的关系出现了重大问题,需要紧急调查。作为COVID-19的治疗方法,FDA最近批准了Remdesivir作为紧急使用授权(EUA)治疗COVID-19的可行性。还有各种可能的抗病毒药物仍在进行临床试验。EUA疫苗广泛推广后,结果表明EUA疫苗对患者的COVID-19控制有效。然而,应该对这些获得许可的疫苗进行审查,以确保它们也能有效地对抗不断增加的SARS-CoV-2变种。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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