{"title":"Composite analysis of COVID-19 cases and urban development status in Taiwan","authors":"Renyou Liu","doi":"10.1117/12.3000116","DOIUrl":"https://doi.org/10.1117/12.3000116","url":null,"abstract":"Every global pandemic in human history has reshaped people's lives, making it imperative for policymakers to adapt to this changing trend in urban planning and management. The SARS-CoV-2 virus that causes COVID-19 is quickly spreading around the world, especially in areas with high population densities. Taiwan had a good performance in the early stages of the epidemic. However, by May 2021, the local epidemic in Taiwan began to break out on a large scale, and the number of local confirmed cases in Taiwan in 2021 reached 14,603. Taiwan is one of the world's regions with the highest population densities and fastest growing economies. Therefore, Taiwan has the title of being one of the Four Asian Tigers. In this study, a composite analysis of Taiwan's population density, economic level, and number of COVID-19 cases was conducted. Based on the composite index CI, correlations were found between COVID-19 infection rates and population density, per capita income, and per capita housing in individual cities.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121742458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of COVID-19 vaccination strategy on pandemic control","authors":"Weiying Sun","doi":"10.1117/12.2691865","DOIUrl":"https://doi.org/10.1117/12.2691865","url":null,"abstract":"The present study reviews the impact of vaccination program strategies in preventing infectious diseases spread, focusing mainly on COVID-19. Vaccination is crucial in achieving herd immunity and infectious diseases spread preventing. The COVID-19 vaccine is classified as a primary vaccine, since it is intended primarily for prevention in susceptible populations. So far, over 5.55 billion people have received at least one dose of the COVID-19 vaccine globally, accounting for approximately 72.3% of the world's population. However, vaccine hesitancy and access to vaccines pose significant challenges to achieving global vaccination coverage. To ensure equitable access to vaccines worldwide, efforts to address these challenges, such as increasing vaccine production capacity, improving distribution channels, and implementing effective communication and education campaigns, are crucial. While all the strategies discussed herein can be useful in different contexts, fractional dosing and intradermal vaccination may be more suitable for lower-income countries due to their cost-effectiveness, while heterologous vaccine regimens may be more suited to higher-income countries with greater access to multiple types of vaccines.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126128630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of intestinal microecological preparations in the health of the elderly","authors":"Jiahe Lin, Huanqian Wang","doi":"10.1117/12.2692641","DOIUrl":"https://doi.org/10.1117/12.2692641","url":null,"abstract":"At present, numerous elderly people are now suffering from diverse geriatric diseases due to the imbalance of intestinal flora.Treating geriatric disease and helping them alleviate their pain has become a research hotspot. Intestinal microecological preparations are living microbes (mainly some probiotics) extracted from some plants and animals aimed to regulate the microbial flora in human intestinal tract after progressing. Lots of advanced clinical trials show that these preparations are therapeutic in Irritable Bowel Syndrome, Acute Infectious Diarrhea, Cancer, Chronic Constipation, Metabolic syndrome, Elderly Critical Illness. In this review, this paper discussed the application and methods to use intestinal microecological preparations to deal with some common diseases of the elderly including some intestinal diseases and chronic diseases and so on. In addition, this paper discussed the future research trend in the intestinal microecological preparations and the method to reduce the incidence of mentioned geriatric disease, ease the pain and prolong the lift span of the elderly.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125455374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimation of the prevalence of hyperuricemia and gout in the U.S. population based on the data from the national health and nutrition examination survey 2017-2018","authors":"Jingyu Pan","doi":"10.1117/12.2692642","DOIUrl":"https://doi.org/10.1117/12.2692642","url":null,"abstract":"There is a pooled prevalence of gout and hyperuricemia, although it varies significantly in different regions. Continuous monitoring of gout and hyperuricemia prevalence will help the government adjust its public health policy. The current analysis employed the research tabulated from the National Health and Nutrition Examination Survey (NHANES) from 2017 to 2018 to measure the prevalence of hyperuricemia that happened through examining the updated nationally representative sample from the US. From 2017 to 2018, it shows a 5.1% of prevalence of gout within the age of 20. In the gender-based criteria for hyperuricemia, the plasma uric acid concentration above 7.0 mg/dL for males while for a female is above 5.7 mg/dL, and the frequency of hyperuricemia was 19.9%. While according to the gender-neutral criteria (i.e., serum urate level above 7.0 mg/dL, no matter which gender), the prevalence of hyperuricemia was 12.6%. The estimate suggests an obvious rise in the prevalence of gout compared to 2015-2016, but the association became nonsignificant after adjusting age, BMI, and hypertension. The burden of gout and hyperuricemia remained high and was increased in absolute numbers, indicating the need for a more proactive approach to patients with hyperuricemia and gout.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130626503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ovarian cancer treatment strategies: focus on PARP inhibitors","authors":"Zimeng Li, Haoyong Li","doi":"10.1117/12.2692606","DOIUrl":"https://doi.org/10.1117/12.2692606","url":null,"abstract":"Ovarian cancer is a common gynecologic malignant tumor, and 70% of them are in the advanced stage of clinical therapy. The primary therapy for newly diagnosed ovarian carcinoma was tumor cell reduction combined with platinum-based chemotherapy. Although most patients achieve clinical remission following initiation of treatment, 70 percent of the patients have a relapse in 2-3 years, with a 5 years survival rate hovering at about 40 percent. More recently, poly- ADP ribose polymerase (ADP-ribose), PARP (PARP) inhibitors have become the first drugs that target DNA damage. PARP inhibitors are lethal by synthesizing DNA repair genes and have been approved for the treatment of BRCA mutations in ovarian and breast cancer. Through PARPDNA capture, PARP inhibitors destabilize the replication fork and cause cell death through replication stress. Inhibitors of poly (ADP-ribose) glycosylases (PARG) exploit and exacerbate cancer cells' replication defects. and can be used as a complement to PARP inhibitors that target various types of cancer. In this paper, I will describe the molecular mechanism of PARP inhibition, highlight the clinical features of the four PARP inhibitors, they discuss the predictive biomarkers of inhibitor susceptibility and resistance mechanism.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128390156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research on university students’ diet affect the quality of sleep","authors":"Lanyi Gao","doi":"10.1117/12.2692445","DOIUrl":"https://doi.org/10.1117/12.2692445","url":null,"abstract":"University students are at high risk of developing sleep problems, and poor sleep quality is often a cause of poorer academic performance. The quality and length of sleep can affect health to a great extent and can lead to several diseases, such as obesity. Dietary factors can also affect the quality of sleep. So how to eat well while maintaining the quality of sleep is something that students need to worry about in addition to their studies. This research study is conducted by collecting and analyzing data through a questionnaire sent to UBC undergraduate students via email. The answers are analyzed using the Qualtrics, and some basic demographic data can be analyzed as a bar chart automatically. The rest of the data will be exported to Excel to calculate scores based on the Diet Quality Index and the Pittsburgh Sleep Quality Index for further analysis. The results show that there is no strong correlation between the quality of diet and the quality of sleep. However, caffeinated beverages have been shown to have a potential relationship with sleep quality (p=0.0922). This study may provide insight into future research directions, such as the extent to which caffeinated beverages may affect sleep quality.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129548984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulation and therapeutic applications of autophagy in cancer","authors":"Yingting Jiang","doi":"10.1117/12.2692769","DOIUrl":"https://doi.org/10.1117/12.2692769","url":null,"abstract":"Autophagy is a cell death mechanism that involves the destruction of substances within an organism's cells in response to several external stresses. A double-membrane structure of autophagosomes transports degradable components, including damaged organelles and misfolded proteins, to lysosomes for breakdown and recycling. With the development of technology, there is accumulating evidence that autophagy is associated with a variety of human disorders, including cancer. During the progression from benign to malignant cancer, autophagy suppresses cancer cells while boosting the growth and spread of cancerous tumor cells. In conclusion, the exploitation of autophagy as a prospective target for the treatment of cancer is becoming an increasingly popular avenue for researchers. This study has reviewed the regulatory processes of autophagy in cancer, the double role of autophagy in cancer, and the therapeutic applications of autophagy in cancer based on the underlying mechanisms of autophagy in cancer for pancreatic cancer, breast cancer, and how existing drugs can inhibit tumor progression.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"107 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129454054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current pathogenesis and approaches to symptom relief of the Alzheimer’s disease","authors":"Le Xu","doi":"10.1117/12.2692845","DOIUrl":"https://doi.org/10.1117/12.2692845","url":null,"abstract":"AD is a degenerative mental disorder that irreversibly causes patients’ cognitive impairment, reduced attention span, emotional disturbances, and personality changes. The current study of the pathogenesis of AD mainly contains the Aβ protein deposit theory, Tau Protein Hyperphosphorylation theory, Central Cholinergic Injury hypothesis and Inflammation hypothesis. This paper seeks to pursue a wider understanding of AD and identify potential breakthroughs in this field by providing a structured summary of the currently proposed pathogenesis and current measures for the mitigation of individual symptoms. Therefore, based on the hypotheses of AD causality, this paper proposes alleviation methods that tackle each of these hypotheses and solutions about Chinese medicine. Through the methods of review and literature analysis, this paper summarizes the system of pathogenesis and relief methods for AD, and discovers that current popular pathologic processes still harbor misconceptions that need further investigation. Only medications that specifically target AD symptoms have been found to be effective in reducing patient discomfort, and some traditional Chinese medicines have been shown to be effective in preventing and treating AD symptoms.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"21 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132165307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The recent application of bioreactor membrane (MBR) in China: for industrial sewage treatment in WWTP and its features","authors":"Wenqi Zhang","doi":"10.1117/12.2691873","DOIUrl":"https://doi.org/10.1117/12.2691873","url":null,"abstract":"This essay provides an overview of bioreactor membrane (MBR) technology and its recent applications in industrial sewage treatment in wastewater treatment plants (WWTP). It begins with an introduction that outlines the importance of industrial sewage treatment and the paper's purpose. It then provides an overview of industrial sewage treatment in WWTP, the current challenges faced in this area, and the need for advanced wastewater treatment technologies. The essay discusses MBR technology, its features and advantages, and how it works in WWTP of industrial wastewater. Next, their benefits and challenges are presented with the recent application of MBR technology in industrial sewage treatment in Shanghai Jinshanwei WWTP. The essay concludes with a summary of the key points discussed, the potential future of MBR technology in industrial sewage treatment, and recommendations for further research and development of MBR technology in this field. Overall, it highlights the importance of MBR treatment methods in addressing the challenges of industrial sewage treatment and emphasizes the need for continued innovation and research in this area.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128479429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Small molecule and biological drugs for treatment of COVID-19","authors":"King Hang Tan","doi":"10.1117/12.3000015","DOIUrl":"https://doi.org/10.1117/12.3000015","url":null,"abstract":"COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a contagious disease. The first case was discovered in Wuhan, China, in December 2019. The symptoms of COVID-19 approximately onset 2-14 days from infection, which are similar to flu and colds, although some patients would be asymptomatic. China is the first place where COVID-19 spreads then worldwide. As a result, the World Health Organisation declared the COVID-19 pandemic on the 12th of March 2020. This announcement hugely affects people’s lifestyles and the world economy. The virus has infected 665 million people and caused about 6.72 million deaths until January 2023, and the data is still growing (WHO). Many effective vaccines have been developed in the short term to prevent the spreading of COVID-19. However, the vaccines could not completely cease the spread of COVID-19 because vaccine effectiveness can vary, and new virus variants keep emerging simultaneously. Therefore, developing COVID-19 drugs is viral for preventing COVID spread and reducing the severity of symptoms.","PeriodicalId":432989,"journal":{"name":"International Conference on Modern Medicine and Global Health","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123677868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}