Cardiovascular Endocrinology & Metabolism最新文献_第9页

Cardiometabolic disease in the older person: prediction and prevention for the generalist physician. 老年人心脏代谢疾病:全科医生的预测和预防。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-02-22 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000193

Alan J Sinclair, Ahmed H Abdelhafiz

引用次数: 16

Effects of aerobic and anaerobic exercise on glucose tolerance in patients with coronary heart disease and type 2 diabetes mellitus. 有氧和无氧运动对冠心病和2型糖尿病患者糖耐量的影响

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-02-21 eCollection Date: 2020-03-01 DOI: 10.1097/XCE.0000000000000188

Bernhard Schwaab, Friderike Kafsack, Edith Markmann, Morten Schütt

{"title":"Effects of aerobic and anaerobic exercise on glucose tolerance in patients with coronary heart disease and type 2 diabetes mellitus.","authors":"Bernhard Schwaab, Friderike Kafsack, Edith Markmann, Morten Schütt","doi":"10.1097/XCE.0000000000000188","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000188","url":null,"abstract":"In patients with coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), physical activity is strongly advised as nonpharmacological therapy. In general, a moderate aerobic exercise intensity is recommended. It was also proposed, however, that greater intensities tend to yield even greater benefits in HbA1c. Hence, the most appropriate exercise intensity seems not to be established yet. We compared the effect of moderate (aerobic) and vigorous (anaerobic) activity on postprandial plasma glucose.Methods: In 10 consecutive patients (63 ± 12 years, BMI 28.3 ± 2.6 kg/m2, fasting plasma glucose 6.1 ± 1.2 mmol/l), 2-hour plasma glucose was ≥11.1 mmol/l in the oral glucose tolerance test at rest (OGTT-0). Cardiopulmonary exercise test (CPX) was performed until a respiratory exchange ratio (RER) ≥1.20, beeing anaerobic (CPX-1), followed by OGTT-1. A steady-state CPX of 30-minute duration was performed targeting an RER between 0.90 and 0.95, being aerobic (CPX-2), followed by OGTT-2.Results: In CPX-1, maximum exercise intensity (maxIntensity) averaged at 99 ± 30 Watt and peak oxygen consumption (VO2peak) reached 15.9 ± 2.8 ml/min/kg. In CPX-2, aerobic intensity averaged at 29 ± 9 Watt, representing 31% of maxIntensity and 61% of VO2peak. After aerobic exercise, 2-hour plasma glucose was significantly reduced to an average of 9.4 ± 2.3 mmol/l (P < 0.05). Anaerobic exercise did not reduce 2-hour plasma glucose as compared to OGTT-0 (12.6 ± 2.2 vs 12.6 ± 3.9 mmol/l).Conclusion: Aerobic exercise intensity was very low in our patients with CHD and T2DM. Postprandial plasma glucose was reduced only by aerobic exercise. Larger studies on the optimal exercise intensity are needed in this patient cohort.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":"9 1","pages":"3-8"},"PeriodicalIF":2.3,"publicationDate":"2020-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000188","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37682571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Acute hyperglycemia and contrast-induced nephropathy in patients with non-ST elevation myocardial infarction. 非st段抬高型心肌梗死患者的急性高血糖和造影剂肾病。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-02-21 eCollection Date: 2020-03-01 DOI: 10.1097/XCE.0000000000000187

Onur Baydar, Alparslan Kilic

{"title":"Acute hyperglycemia and contrast-induced nephropathy in patients with non-ST elevation myocardial infarction.","authors":"Onur Baydar, Alparslan Kilic","doi":"10.1097/XCE.0000000000000187","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000187","url":null,"abstract":"Acute hyperglycemia and contrast-induced nephropathy (CIN) are frequently observed in non-ST elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI), and both are associated with an increased mortality rate. We investigated the possible association between acute hyperglycemia and CIN in patients with NSTEMI undergoing PCI.Materials and methods: We retrospectively enrolled 281(149, 53% men) NSTEMI patients undergoing PCI. For each patient, plasma glucose levels were secreened at hospital admission. Acute hyperglycemia was defined as glucose levels > 198 mg/dl. CIN was defined as an increase in serum creatinine 25% or 0.5 mg/dl from baseline in the first 48-72 hours.Results: Overall, 44 (15.7%) patients had acute hyperglycemia. Patients with acute hyperglycemia had higher incidence of CIN than those without acute hyperglycemia (29.5 vs 5.1%, P < 0.001). Also, in-hospital mortality, length of hospital stay, major bleeding, requirement of mechanical ventilation and dialysis were observed significantly higher in patients with hyperglycemia. Patients were then reallocated to two groups according to the presence or absence of CIN. Overall, 25 cases (8.9%) of CIN were diagnosed. Diabetes mellitus, weight, age, glucose level and estimated glomerular filtration rate (eGFR) were detected as independent risk factors of CIN. Additionally, admission glucose levels were significantly correlated with creatinine levels after PCI, eGFR and contrast volume/eGFR ratio.Conclusion: In NSTEMI patients undergoing primary PCI, acute hyperglycemia may be associated with an increased risk for CIN and in-hospital mortality and morbidity.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":"9 1","pages":"24-29"},"PeriodicalIF":2.3,"publicationDate":"2020-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000187","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37683415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A treatment-based algorithm for identification of diabetes type in the National Health and Nutrition Examination Survey. 一种基于治疗方法的国民健康与营养检查调查中糖尿病类型识别算法。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-02-21 eCollection Date: 2020-03-01 DOI: 10.1097/XCE.0000000000000189

Mitra Mosslemi, Hannah L Park, Christine E McLaren, Nathan D Wong

{"title":"A treatment-based algorithm for identification of diabetes type in the National Health and Nutrition Examination Survey.","authors":"Mitra Mosslemi, Hannah L Park, Christine E McLaren, Nathan D Wong","doi":"10.1097/XCE.0000000000000189","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000189","url":null,"abstract":"In epidemiology studies, identification of diabetes type (type 1 vs. type 2) among study participants with diabetes is important; however, conventional diabetes type identification approaches that include age at diabetes diagnosis as an initial criterion introduces biases. Using data from the National Health and Nutrition Examination Survey, we have developed a novel algorithm which does not include age at diagnosis to identify participants with self-reported diagnosed diabetes as having type 1 vs. type 2 diabetes.Methods: A total of 5457 National Health and Nutrition Examination Survey participants between cycles 1999-2000 and 2015-2016 reported that a health professional had diagnosed them as having diabetes at a time other than during pregnancy and had complete information on diabetes-related questions. After developing an algorithm based on information regarding the treatment(s) they received, we classified these participants as having type 1 or type 2 diabetes.Results: The treatment-based algorithm yielded a 6-94% split for type 1 and type 2 diabetes, which is consistent with reports from the Centers for Disease Control and other resources. Moreover, the demographics and clinical characteristics of the assigned type 1 and type 2 cases were consistent with contemporary epidemiologic findings.Conclusion: Applying diabetes treatment information from the National Health and Nutrition Examination Survey, as formulated in our treatment-based algorithm, may better identify type 1 and type 2 diabetes cases and thus prevent the specific biases imposed by conventional approaches which include the age of diabetes diagnosis as an initial criterion for diabetes type classification.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":"9 1","pages":"9-16"},"PeriodicalIF":2.3,"publicationDate":"2020-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37682572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Comparing inpatient costs of heart failure admissions for patients with reduced and preserved ejection fraction with or without type 2 diabetes. 比较射血分数降低和保留的伴有或不伴有2型糖尿病的心力衰竭患者住院费用。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-02-21 eCollection Date: 2020-03-01 DOI: 10.1097/XCE.0000000000000190

Natalia Olchanski, Amanda R Vest, Joshua T Cohen, David DeNofrio

{"title":"Comparing inpatient costs of heart failure admissions for patients with reduced and preserved ejection fraction with or without type 2 diabetes.","authors":"Natalia Olchanski, Amanda R Vest, Joshua T Cohen, David DeNofrio","doi":"10.1097/XCE.0000000000000190","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000190","url":null,"abstract":"Both heart failure (HF) and diabetes mellitus (DM) account for major healthcare expenditures. We evaluated inpatient expenditures and cost drivers in patients admitted with HF with and without DM.Methods: We created a retrospective cohort of acutely decompensated HF patients, using linked data from cost accounting systems and electronic medical records. We stratified patients by LVEF into reduced ejection fraction (HFrEF, LVEF ≤40%) and preserved ejection fraction (HFpEF, LVEF >40%) groups and by DM status at admission.Results: Our population had 544 people: 285 HFrEF patients (43.5% with DM) and 259 HFpEF patients (43.6% with DM). Patients with HFrEF and DM had the longest hospital stay (5.10 ± 5.21 days). Patients with HFrEF and DM had the highest hospitalization cost ($11 576 ± 15 818). HFrEF and HFpEF patients with DM had the highest cost, and cost per day alive was highest for HFpEF patients with DM [$3153 (95% CI 2332, 4262)].Conclusion: Overall cost was higher for patients with DM, whether or not they were admitted with acute HF due to HFrEF or HFpEF. Cost per day alive for patients with DM continued to exceed corresponding costs for patients without DM, with HFpEF patients with DM having the highest cost.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":"9 1","pages":"17-23"},"PeriodicalIF":2.3,"publicationDate":"2020-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37683414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Exercise prescription in patients with type 2 diabetes and coronary heart disease: could less be more? 2型糖尿病和冠心病患者的运动处方:少就是多吗?

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-02-21 eCollection Date: 2020-03-01 DOI: 10.1097/XCE.0000000000000196

Stephan Jacob, Andrew J Krentz

引用次数: 7

Ventricular fibrillation associated with Graves' disease and amiodarone induced thyrotoxicosis. 与巴塞杜氏病和胺碘酮诱发的甲状腺毒症有关的室颤。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2019-11-13 eCollection Date: 2019-12-01 DOI: 10.1097/XCE.0000000000000184

Jake Cho, Bosede Afolabi

引用次数: 0

The comparison of the relationships about the presence of branch retinal vein occlusion and endothelial functions between diabetic and non-diabetic patients. 糖尿病与非糖尿病患者视网膜分支静脉阻塞与内皮功能关系的比较。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2019-11-13 eCollection Date: 2019-12-01 DOI: 10.1097/XCE.0000000000000185

Vahit Demir, Mehmet Tolga Dogru, Zafer Onaran, Huseyin Kandemir, Caglar Alp

{"title":"The comparison of the relationships about the presence of branch retinal vein occlusion and endothelial functions between diabetic and non-diabetic patients.","authors":"Vahit Demir, Mehmet Tolga Dogru, Zafer Onaran, Huseyin Kandemir, Caglar Alp","doi":"10.1097/XCE.0000000000000185","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000185","url":null,"abstract":"Objectives: The aim of this study was to investigate the endothelial functions in both patients with diabetics and non-diabetics with branch retinal vein occlusion by using pulse wave analysis and flow-mediated dilatation methods.Patients and methods: This cross-sectional study included a total of 136 participants (47 diabetic patients with branch retinal vein occlusion, 43 non-diabetic patients with branch retinal vein occlusion, and 46 otherwise healthy subjects). Evaluation of endothelial functions was performed by flow-mediated dilatation and pulse wave analysis methods. Stiffness index, reflection index (RI), and pulse propagation time were calculated.Results: The mean stiffness index and RI were significantly higher in the diabetic branch retinal vein occlusion group compared with the non-diabetic branch retinal vein occlusion and the healthy controls (for stiffness index: 11.5 ± 2.8 vs. 10.1 ± 2.5 and 8.3 ± 2.0, P < 0.001; and for RI: 75.1 ± 11.7 vs. 65.4 ± 8.4 and 60.2 ± 18.8, P < 0.001, respectively), whereas the pulse propagation time was significantly lower in the diabetic group (156.4 ± 32.3 vs. 174.4 ± 46.5 and 205.0 ± 58.5, P < 0.001, respectively). There was a significant negative correlation between visual acuity and stiffness index (r = -0.512, P < 0.001). Besides, there was also a significant positive correlation between visual acuity and pulse propagation time (r = 0.398, P < 0.001).Conclusion: This study demonstrated that the stiffness index and RI values were higher in patients with branch retinal vein occlusion compared to the healthy subjects.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":"8 4","pages":"109-114"},"PeriodicalIF":2.3,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37546500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Left ventricular mass index and subendocardial myocardial function in children with chronic kidney disease, a transmural strain and three-dimensional echocardiographic study. 慢性肾脏疾病患儿左心室质量指数和心内膜下心肌功能:经壁应变和三维超声心动图研究

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2019-11-13 eCollection Date: 2019-12-01 DOI: 10.1097/XCE.0000000000000186

Amira Esmat El Tantawy, Fatina Fadel, Safaa M Abdelrahman, Marwa Nabhan, Reem Ibrahim, Aya M Fattouh, Shaimaa Sayed, Khaled Mohamed ElKhashab, Peter Afdal, Antoine Fakhry AbdelMassih

{"title":"Left ventricular mass index and subendocardial myocardial function in children with chronic kidney disease, a transmural strain and three-dimensional echocardiographic study.","authors":"Amira Esmat El Tantawy, Fatina Fadel, Safaa M Abdelrahman, Marwa Nabhan, Reem Ibrahim, Aya M Fattouh, Shaimaa Sayed, Khaled Mohamed ElKhashab, Peter Afdal, Antoine Fakhry AbdelMassih","doi":"10.1097/XCE.0000000000000186","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000186","url":null,"abstract":"Introduction: Left ventricular hypertrophy (LVH) is the commonest myocardial response to chronic kidney disease (CKD); this response has been regarded detrimental as it impairs the blood flow to the deepest layers of the myocardium causing progressive myocardial dysfunction. The aim of these series is to assess the determinants of LVH in CKD patients and its impact on subendocardial function in such patients.Methods: This study has been conducted on 40 CKD patients (Group 1) and 40 age-matched controls, both groups were assessed by transmural echocardiography to determine the subepicardial and subendocardial global longitudinal strain (GLS) as an expression of the systolic function of each of those layers. LVH was assessed by calculation of left ventricle mass index (LVMI). Both groups underwent ambulatory blood pressure monitoring. Group 1 was assessed as regards lipid profile and insulin resistance by homeostasis model assessment of insulin resistance (HOMA-IR).Results: HOMA-IR proved to be a more important determinant of LV hypertrophy than SBP and DBP with a P of 0.01. Moreover subendocardial GLS was negatively correlated with LVMI with r = 0.69 and P < 0.01 denoting the negative effect. LVH plays on subendocardial function probably by impairing myocardial perfusion.Conclusion: This study points toward the importance of insulin resistance in aggravation of myocardial remodeling in CKD patients; more studies are warranted to examine the role of insulin Sensitizers in reversing such remodeling and restoring subendocardial function in such important systemic disorder.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":"8 4","pages":"115-118"},"PeriodicalIF":2.3,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000186","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37546425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Further insights into cardiovascular outcomes in diabetic and non-diabetic states: inhibition of sodium-glucose co-transports. 进一步了解糖尿病和非糖尿病状态的心血管结局:钠-葡萄糖共转运的抑制。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2019-11-13 eCollection Date: 2019-12-01 DOI: 10.1097/XCE.0000000000000178

Zhao Li

引用次数: 0