Cardiovascular Endocrinology & Metabolism最新文献_第9页

Obese communities among the best predictors of COVID-19-related deaths. 肥胖社区是covid -19相关死亡的最佳预测指标之一。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-11 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000218

Antoine Fakhry AbdelMassih, Ramy Ghaly, Abeer Amin, Amr Gaballah, Aya Kamel, Bassant Heikal, Esraa Menshawey, Habiba-Allah Ismail, Hend Hesham, Josephine Attallah, Kirollos Eshak, Mai Moursi, Mariam Khaled-Ibn-ElWalid, Marwa Tawfik, Mario Tarek, Mayan Mohy-El-Din, Menna Habib, Nada Hafez, Odette Bahnan, Passant Ismail, Sara Senoussy, Sherry Ghaly, Sousanna Farah, Rafeef Hozaien, Veronia Adel, Mariam Khaled

{"title":"Obese communities among the best predictors of COVID-19-related deaths.","authors":"Antoine Fakhry AbdelMassih, Ramy Ghaly, Abeer Amin, Amr Gaballah, Aya Kamel, Bassant Heikal, Esraa Menshawey, Habiba-Allah Ismail, Hend Hesham, Josephine Attallah, Kirollos Eshak, Mai Moursi, Mariam Khaled-Ibn-ElWalid, Marwa Tawfik, Mario Tarek, Mayan Mohy-El-Din, Menna Habib, Nada Hafez, Odette Bahnan, Passant Ismail, Sara Senoussy, Sherry Ghaly, Sousanna Farah, Rafeef Hozaien, Veronia Adel, Mariam Khaled","doi":"10.1097/XCE.0000000000000218","DOIUrl":"10.1097/XCE.0000000000000218","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is the largest outbreak to strike the world since the Spanish flu in 1918. Visual examination of the world map shows a wide variation of death tolls between countries. The main goal of our series is to determine the best predictors of such discrepancy.Methods: This is a retrospective study in which the rate of COVID-19 deaths was correlated with each of the following independent variables: total tests per 1 million population, gross domestic product (GDP), average temperatures per country, ultraviolet index, median age, average BMI per country, food supply, Bacille Calmette-Guerin compulsory status, and passenger traffic.Results: BMI per country proved to be the second best predictor of death rate with an R value of 0.43, and GDP being the best predictor with R = 0.65.Conclusion: This article shows a tight correlation between average BMI, food supply per country, and COVID-19-related deaths. Such predisposing factors might operate by upregulating the inflammation pathway in heavily struck countries, leading to easier triggering of the infamous cytokine storm syndrome. Obesity also increases cardiovascular and respiratory morbidities, which are coupled to increased ICU demand and deaths among infected cases.Video abstract: http://links.lww.com/CAEN/A25.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38271995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Estimating life years lost to diabetes: outcomes from analysis of National Diabetes Audit and Office of National Statistics data. 估计糖尿病损失的寿命年:来自国家糖尿病审计和国家统计局数据分析的结果。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-02 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000210

Adrian H Heald, Mike Stedman, Mark Davies, Mark Livingston, Ramadan Alshames, Mark Lunt, Gerry Rayman, Roger Gadsby

{"title":"Estimating life years lost to diabetes: outcomes from analysis of National Diabetes Audit and Office of National Statistics data.","authors":"Adrian H Heald, Mike Stedman, Mark Davies, Mark Livingston, Ramadan Alshames, Mark Lunt, Gerry Rayman, Roger Gadsby","doi":"10.1097/XCE.0000000000000210","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000210","url":null,"abstract":"With sustained growth of diabetes numbers, sustained patient engagement is essential. Using nationally available data, we have shown that the higher mortality associated with a diagnosis of T1DM/T2DM could produces loss of 6.4 million future life years in the current UK population. In the model, the 'average' person with T1DM (age 42.8 years) has a life expectancy from now of 32.6 years, compared to 40.2 years in the equivalent age non diabetes mellitus population, corresponding to lost life years (LLYs) of 7.6 years/average person. The 'average' person with T2DM (age 65.4 years) has a life expectancy from now of 18.6 years compared to the 20.3 years for the equivalent non diabetes mellitus population, corresponding to LLY of 1.7 years/average person. We estimate that for both T1DM and T2DM, one year with HbA1c >58 mmol/mol loses around 100 life days. Linking glycaemic control to mortality has the potential to focus minds on effective engagement with therapy and lifestyle recommendation adherence.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673790/pdf/xce-9-183.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38641608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 66

Hypertension and diabetes mellitus in patients with COVID 19: a viewpoint on mortality. 新冠肺炎合并高血压和糖尿病患者的死亡率观点。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-02 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000213

Didem Tascioglu, Kenan Yalta, Ertan Yetkin

{"title":"Hypertension and diabetes mellitus in patients with COVID 19: a viewpoint on mortality.","authors":"Didem Tascioglu, Kenan Yalta, Ertan Yetkin","doi":"10.1097/XCE.0000000000000213","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000213","url":null,"abstract":"The outbreak of coronavirus disease 2019 (COVID 19) by the novel corona virus SARS-CoV2 is the leading worldwide healthcare problem due to its contagious nature, high morbidity and mortality rates. The present pandemic has also brought an emerging situation regarding the cardiovascular complications and comorbid disease mainly pointing out hypertension (HT) and diabetes mellitus (DM). Early clinical observations have shown that HT and DM are the main comorbid disease along with cardiovascular disease, chronic obstructive lung disease and malignancies [1]. The incidences of hypertension, cardiacerebrovascular diseases and diabetes have been found to be about twofold, three and twofold, respectively, higher in ICU/severe cases than in their non-ICU/ severe counterparts by the meta-analysis of Li et al. [2]. Similarly the age and certain co-morbidities (hypertension, diabetes, etc.) have been reported to be important risk factors for mortality among the 25 death cases of with COVID-19 [1]. This worrisome situation has been further aggravated by the potential upregulation of angiotensin converting enzyme 2 in hypertensive and diabetic patients and, more interestingly, in those receiving angiotensin converting enzyme inhibitors and angiotensin receptor antagonists, thereby facilitating the inoculation of lung tissue by COVID 19 [3]. Within this context, these findings might be regarded as an alerting scenario with gloomy consequences for those with HT and DM. This concern has been surpassed by the recommendation of cardiovascular societies against to the discontinuation of angiotensin converting enzyme inhibitors and rennin–angiotensin aldosteron antagonist due to the outbreak of COVID 19 [4].","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38271996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Relationship between a single measurement at baseline of body mass index, glycated hemoglobin, and the risk of mortality and cardiovascular morbidity in type 2 diabetes mellitus. 2型糖尿病患者体重指数、糖化血红蛋白基线单次测量与死亡率和心血管发病率之间的关系

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-25 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000202

Oliver Brown, Pierluigi Costanzo, Andrew L Clark, Gianluigi Condorelli, John G F Cleland, Thozhukat Sathyapalan, David Hepburn, Eric S Kilpatrick, Stephen L Atkin

{"title":"Relationship between a single measurement at baseline of body mass index, glycated hemoglobin, and the risk of mortality and cardiovascular morbidity in type 2 diabetes mellitus.","authors":"Oliver Brown, Pierluigi Costanzo, Andrew L Clark, Gianluigi Condorelli, John G F Cleland, Thozhukat Sathyapalan, David Hepburn, Eric S Kilpatrick, Stephen L Atkin","doi":"10.1097/XCE.0000000000000202","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000202","url":null,"abstract":"Objective: This study aims to evaluate the relationship between a single measurement at baseline of body mass index (BMI), glycated hemoglobin (HbA1c) and subsequent clinical outcomes in patients with type 2 diabetes mellitus (T2DM).Method: Patients with T2DM were recruited from an outpatient diabetes clinic in a single large teaching hospital in Kingston upon Hull, UK. At baseline, demographics and HbA1c were recorded. Patients were categorized by BMI: normal weight (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), and obese (>30 kg/m2). Multivariable Cox regression models that included demographic, risk factors, and comorbidities were separately constructed for all-cause, cardiovascular, cancer and sepsis-related mortality, using four groups of HbA1c (<6%, 6.0-6.9%, 7.0-7.9%, and >8%).Results: In total, 6220 patients with T2DM (median age 62 years, 54% male) were followed for a median of 10.6 years. HbA1c levels >8.0% were associated with increased risk of all-cause mortality and cardiovascular death. However, this increased risk was not consistent across the weight categories and reached statistical significance only in overweight patients (BMI 25-29.9 kg/m2).Conclusions: In a large cohort of patients with T2DM elevated HbA1c levels at baseline did not consistently predict increased risk of all-cause and cardiovascular mortality across the different BMI categories.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673766/pdf/xce-9-177.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38641607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Pathogenesis and remission of type 2 diabetes: what has the twin cycle hypothesis taught us? 2 型糖尿病的发病机制和缓解：双循环假说给了我们什么启示？

IF 1.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-25 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000201

Ahmad Al-Mrabeh

引用次数: 0

Revisiting the pathogenic role of insulin resistance in Duchenne muscular dystrophy cardiomyopathy subphenotypes. 胰岛素抵抗在杜氏肌营养不良型心肌病亚表型中的致病作用。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-18 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000203

Antoine Fakhry AbdelMassih, Reem Esmail, Hanan Zekri, Ahmed Kharabish, Khaled ElKhashab, Rahma Menshawey, Habiba-Allah Ismail, Peter Afdal, Erini Farid, Omneya Affifi

{"title":"Revisiting the pathogenic role of insulin resistance in Duchenne muscular dystrophy cardiomyopathy subphenotypes.","authors":"Antoine Fakhry AbdelMassih, Reem Esmail, Hanan Zekri, Ahmed Kharabish, Khaled ElKhashab, Rahma Menshawey, Habiba-Allah Ismail, Peter Afdal, Erini Farid, Omneya Affifi","doi":"10.1097/XCE.0000000000000203","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000203","url":null,"abstract":"Introduction: Duchenne muscular dystrophy (DMD) is known to impact the subepicardial layer of the myocardium through chronic inflammation. Recent animal studies have shown predominant subendocardial involvement in rats with DMD. The primary outcome parameter was to determine by cardiovascular MRI (CMR) if two differential patterns of myocardial involvements exist in DMD; the secondary outcome parameters were to correlate the observed pattern with metabolic markers such as insulin resistance measures.Methods: Forty patients with DMD were screened using CMR to determine which of them had predominantly subendocardial dysfunction (SENDO group), or subepicardial/midmyocardial involvement (SEPMI group). Patients were subjected to body mass index measurement, serum creatinine kinase, serum lactate dehydrogenase enzyme, fasting glucose-insulin ratio (FGIR), full lipid profile, left ventricular ejection fraction (LVEF), left ventricle E/E´ ratio (the ratio of early mitral inflow velocity to average early diastolic velocities of the basal septum and mitral annulus) for left ventricle diastolic function, and myocardial layer strain discriminating echocardiography (MLSD-STE). Results: 26 patients displayed SENDO while 34 displayed SEPMI. SENDO group displayed overt insulin resistance; (FGIR (SENDO: 7 ± 1 vs. SEPMI: 5 ± 1, P < 0.001). FGIR was negatively correlated with Subendocardial Global Longitudinal Strain (ENDO-LS) with r = -0.75.Conclusion: DMD does not seem to influence the heart uniformly; DMD cardiomyopathy probably has two separate phenotypes with different mechanisms. Insulin resistance might be implicated in its pathogenesis and its reversal may help to slow disease progression.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38641605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Preventive cardiology or cardiometabolic medicine: a new and emerging subspecialty? 预防心脏病学还是心脏代谢医学:一个新兴的亚专科?

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-18 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000206

Nathan D Wong

{"title":"Preventive cardiology or cardiometabolic medicine: a new and emerging subspecialty?","authors":"Nathan D Wong","doi":"10.1097/XCE.0000000000000206","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000206","url":null,"abstract":"While we have seen great reductions in cardiovascular disease (CVD) morbidity and mortality over the past few decades, the rate of these declines has recently diminished, and there is even evidence that CVD mortality may be on the rise once again [1]. Much of this is fueled by the epidemic of obesity, metabolic syndrome and type 2 diabetes [2]. There is a wealth of evidence regarding the efficacy of cholesterol-lowering medications (particularly statins), blood pressure control, and most recently the treatment of diabetes with newer medications that positively impact CVD outcomes [2]. Yet recent data continue to demonstrate inadequate adherence to preventive medications and inadequate control of risk factors [3,4]. Even in the case of diabetes, where CVD is the major cause of morbidity and mortality, while many patients are at reasonable targets for HbA1c, blood pressure, and low-density lipoprotein-cholesterol individually, 20% or fewer are at all three targets simultaneously, suggesting a lack of coordinated care and understanding of the priorities that should be placed to reduce CVD risk in such persons [5]. Moreover, there is a continued rise in obesity both in developing and developed nations, with this closely linked to other cardiometabolic risk factors such as blood pressure and dyslipidemia, as well as being a strong determinant of type 2 diabetes. Consequently, there is an urgency for healthcare providers from different specialties to come together to address together the CVD risks common in many patients if we are to reduce, or at least prevent an imminent rise in CVD morbidity and mortality moving forward. While clearly there has been great progress made in the treatment of persons with known CVD, if we are to make further progress in the next few decades, there needs to be a shift in focus in cardiovascular medicine towards promoting cardiovascular health and prevention. A specialized field of preventive cardiology or cardiometabolic medicine [2] is meant to address this need.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000206","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38279791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Relative frequency of cardiology vs. endocrinology visits by type 2 diabetes patients with cardiovascular disease in the USA: implications for implementing evidence-based use of glucose-lowering medications. 美国伴有心血管疾病的2型糖尿病患者心脏病科与内分泌科就诊的相对频率:对实施循证降糖药物的影响

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-15 eCollection Date: 2020-06-01 DOI: 10.1097/XCE.0000000000000195

Felona Gunawan, Michael E Nassif, Caitlin Partridge, Tariq Ahmad, Mikhail Kosiborod, Silvio E Inzucchi

{"title":"Relative frequency of cardiology vs. endocrinology visits by type 2 diabetes patients with cardiovascular disease in the USA: implications for implementing evidence-based use of glucose-lowering medications.","authors":"Felona Gunawan, Michael E Nassif, Caitlin Partridge, Tariq Ahmad, Mikhail Kosiborod, Silvio E Inzucchi","doi":"10.1097/XCE.0000000000000195","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000195","url":null,"abstract":"Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in type 2 diabetes (T2D) patients. Recent cardiovascular outcome trials demonstrated clear cardiovascular benefits of novel classes of glucose-lowering agents. We performed retrospective electronic health record review at two major healthcare systems in the USA to determine the relative frequencies of outpatient encounters (hence prescribing opportunities) that a patient with T2D and CVD had with a cardiologist vs. an endocrinologist over one-year period. Of 109 747 T2D patients, 42.6% had established CVD. The ratio of cardiology-to-endocrinology outpatient encounters was 2.0:1 for all T2D patients, and 4.1:1 for those with T2D and CVD. Because each outpatient encounter provides an opportunity to discuss glucose-lowering medications with cardiovascular benefits, the much greater frequency of cardiology encounters highlights the emerging potential for cardiovascular specialists to influence or even implement evidence-based glucose-lowering therapies, thereby improving cardiovascular outcomes in their T2D patients.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38044013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Associations of adiponectin and leptin with brain natriuretic peptide in African Americans: the Jackson Heart Study. 非裔美国人的脂联素和瘦素与脑利钠肽的关系:杰克逊心脏研究。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-15 eCollection Date: 2020-06-01 DOI: 10.1097/XCE.0000000000000198

Steven R Horbal, Michael E Hall, Paul C Dinh, Abbas Smiley, Solomon K Musani, Jiankang Liu, Herman A Taylor, Ervin R Fox, Aurelian Bidulescu

{"title":"Associations of adiponectin and leptin with brain natriuretic peptide in African Americans: the Jackson Heart Study.","authors":"Steven R Horbal, Michael E Hall, Paul C Dinh, Abbas Smiley, Solomon K Musani, Jiankang Liu, Herman A Taylor, Ervin R Fox, Aurelian Bidulescu","doi":"10.1097/XCE.0000000000000198","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000198","url":null,"abstract":"Brain natriuretic peptide (BNP) is elevated in decompensated systolic and diastolic heart failure. The plasma levels of adipokines, such as adiponectin and leptin, may provide evidence for mechanistic differences in BNP concentrations. African-American-specific associations are limited in the literature. The objective of this study was to evaluate the associations of adiponectin and leptin with BNP among African Americans.Methods: Linear and logistic regressions were used to test the associations between adiponectin, leptin, and plasma BNP in 3738 participants of the Jackson Heart Study (JHS), a single-site prospective cohort study of African Americans in Jackson, Mississippi.Results: A direct relationship of adiponectin was observed in multiple multivariate-adjusted linear models: in men (β = 0.41-0.47), and in women (β = 0.32-0.38). Those in the highest quartile of adiponectin expression were twice as likely to have elevated BNP levels after adjustment [odds ratio 2.66 (95% confidence interval, 1.66-4.34)]. An inverse relationship of leptin with BNP was observed (β = -0.15) but attenuated after adjustment for aldosterone, renin, and adiponectin.Conclusions: Different linear associations of adiponectin and leptin with BNP were observed. Odds of elevated adiponectin were observed with elevated BNP in multivariate-adjusted models. This paradoxical relationship of adiponectin and plasma BNP is possibly explained through adiponectin resistance.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38044012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Clinical presentation of paroxysmal supraventricular tachycardia: evaluation of usual and unusual symptoms. 阵发性室上性心动过速的临床表现:通常和不寻常症状的评价。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-05-15 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000208

Ertan Yetkin, Selcuk Ozturk, Bilal Cuglan, Hasan Turhan

{"title":"Clinical presentation of paroxysmal supraventricular tachycardia: evaluation of usual and unusual symptoms.","authors":"Ertan Yetkin, Selcuk Ozturk, Bilal Cuglan, Hasan Turhan","doi":"10.1097/XCE.0000000000000208","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000208","url":null,"abstract":"Objective: Clinical presentation of paroxysmal supraventricular tachycardia may vary from asymptomatic occurrence or mild perception of palpitation to severe chest pain or syncope. This variation is the most challenging issue in the diagnostic evaluation of rhythm disturbances and paroxysmal supraventricular tachycardia as well. This study sought to evaluate the symptoms during the tachycardia attack or index event in patients who underwent electrophysiological study and ablation procedure.Methods: This retrospective study included 100 consecutive patients who underwent electrophysiological study and ablation procedures due to supraventricular tachycardia. Structural heart disease, moderate/severe valvular pathology, systemic pathologies, such as connective tissue disease and chronic obstructive lung disease, history of pacemaker implantation was defined as exclusion criteria. In addition, medically managed patients and patients with unsuccessful ablation were not included in the study.Results: Palpitation was the most frequently observed symptom in 84% of patients, followed by chest pain in 47%, dyspnea in 38%, syncope 26%, lightheadedness in 19%, and sweating in 18% of the patients. The most common symptoms after tachycardia event were fatigue and lightheadedness with frequencies of 56% and 55%, respectively. Forty-five percent of the patients reported more than one, unusually frequent urination within the following 1-3 hours after the index event.Conclusions: Paroxysmal supraventricular tachycardia might manifest itself as gastrointestinal, neurological, psychosomatic symptoms, and unusual complaints in association with or without main symptoms, including palpitation, chest pain, syncope, and dyspnea. Symptoms after tachycardia or index event should be questioned systematically.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673777/pdf/xce-9-153.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38641603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5