Cardiovascular Endocrinology & Metabolism最新文献_第8页

Cardiometabolic medicine - the US perspective on a new subspecialty. 心脏代谢医学--美国对新亚专科的看法。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-07-16 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000224

Cara Reiter-Brennan, Miguel Cainzos-Achirica, Garshasb Soroosh, David R Saxon, Michael J Blaha, Robert H Eckel

{"title":"Cardiometabolic medicine - the US perspective on a new subspecialty.","authors":"Cara Reiter-Brennan, Miguel Cainzos-Achirica, Garshasb Soroosh, David R Saxon, Michael J Blaha, Robert H Eckel","doi":"10.1097/XCE.0000000000000224","DOIUrl":"10.1097/XCE.0000000000000224","url":null,"abstract":"The high prevalence of cardiovascular disease and worldwide diabetes epidemic has created an ever-increasing burden on the healthcare system. This calls for the creation of a new medicine subspecialty: cardiometabolic medicine. Using information from review articles listed on PubMed and professional society guidelines, the authors advocate for a cardiometabolic medicine specialization training program. The curriculum would integrate relevant knowledge and skills of cardiology and endocrinology as well as content of other disciplines essential to the optimal care of cardiometabolic patients, such as epidemiology, biostatistics, behavioral science and psychology. Cardiometabolic medicine should be seen as an opportunity for life-long learning, with core concepts introduced in medical school and continuing through CME courses for practicing physicians. To improve care for complex patients with multiple co-morbidities, a paradigm shift must occur, transforming siloed education, and treatment and training to interdisciplinary and collaborative work.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410029/pdf/xce-9-070.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38279793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Black esophagus and diabetes: a close relationship. 黑色食道与糖尿病:关系密切。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-07-07 eCollection Date: 2021-03-01 DOI: 10.1097/XCE.0000000000000221

Laura Rodriguez Fernandez, María Concepción García Sánchez, José María Prieto de Paula, José Pablo Miramontes González

引用次数: 1

Rapid progression of aortic stenosis after initiation of teriparatide treatment: a case report. 特立帕肽治疗后主动脉瓣狭窄快速进展一例报告。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-07-07 eCollection Date: 2021-03-01 DOI: 10.1097/XCE.0000000000000220

Arie Solomon, Shlomo Birkenfeld

{"title":"Rapid progression of aortic stenosis after initiation of teriparatide treatment: a case report.","authors":"Arie Solomon, Shlomo Birkenfeld","doi":"10.1097/XCE.0000000000000220","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000220","url":null,"abstract":"Introduction: Teriparatide, a recombinant formulation of endogenous PTH, is indicated for the treatment of osteoporosis in patients at high risk for fracture including postmenopausal women, men with primary or hypogonadal osteoporosis and patients with glucocorticoid-induced osteoporosis.Case report: A 64-year-old Jewish osteoporotic woman initiated use of Teriparatide (FORTEOTM, 250 µg per 1 ml subcutaneously per day) in April 2018. Prior to therapy initiation, the patient has undergone eight echocardiograms with an aortic valve pressure gradient ranging between 29 and 39 mmHg, defined as mild aortic stenosis (AS), with no clear trend of progression. In two subsequent echo tests conducted 4 and 7 months after treatment initiation, there was a rapid progression of AS with gradient pressures of 55 and 58 mmHg, respectively.Conclusion: Intermittent exposure to PTH analogues may be one of the causes of rapid progression of AS. Studies with sizeable populations are required to assess causal relationship between PTH analogues use and progression of AS.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901823/pdf/xce-10-56.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25406753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Type 2 diabetes prevalence in Pakistan: what is driving this? Clues from subgroup analysis of normal weight individuals in diabetes prevalence survey of Pakistan. 巴基斯坦的 2 型糖尿病患病率：是什么导致了这一现象？巴基斯坦糖尿病患病率调查中对体重正常者进行的亚组分析提供的线索。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-19 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000212

Azizul Hasan Aamir, Zia Ul-Haq, Sheraz Fazid, Basharat Hussain Shah, Abbas Raza, Ali Jawa, Saeed A Mahar, Ibrar Ahmad, Faisal Masood Qureshi, Adrian H Heald

{"title":"Type 2 diabetes prevalence in Pakistan: what is driving this? Clues from subgroup analysis of normal weight individuals in diabetes prevalence survey of Pakistan.","authors":"Azizul Hasan Aamir, Zia Ul-Haq, Sheraz Fazid, Basharat Hussain Shah, Abbas Raza, Ali Jawa, Saeed A Mahar, Ibrar Ahmad, Faisal Masood Qureshi, Adrian H Heald","doi":"10.1097/XCE.0000000000000212","DOIUrl":"10.1097/XCE.0000000000000212","url":null,"abstract":"Background: Type 2 diabetes mellitus (T2DM) is a global health tissue. We determined factors relating to the likelihood of developing T2DM in normal BMI individuals.Methodology: This was a cross-sectional community-based representative survey, of people aged ≥20 years in Pakistan, using HBA1c as the screening tool. The prevalence of T2DM/prediabetes in people having normal BMI together with associated risk factors was estimated.Results: Of 6824 normal BMI individuals, there was still a high prevalence of T2DM 14.92% and in underweight at 10.14% (overall prevalence 16.96%). Corresponding rates for prediabetes for the normal BMI category: 9.79% and underweight 8.99%. Multivariate logistic regression modeling for normal BMI individuals, showed a significantly increased risk of T2DM with increasing age (odds ratio [OR] 2.1, 3.3, 4.5 and 4.8, P < 0.001 for 31-40, 41-50, 51-60 and 61 years and above respectively, compared to age decade 20-30 years). Similarly, there was a significantly high risk of T2DM with lower education level [OR for no vs graduate 2.4, 95% confidence interval (CI) 1.5-3.8]. There was a significantly increased risk of T2DM in individuals having a positive family history [OR 4.3 (95% CI 7.0-11.5)]. Overall the influence of overweight/obese on T2DM occurrence (20% increased risk) was much less than in other regions of the world.Conclusion: There are higher than expected rates of T2DM/prediabetes in Pakistani ethnicity normal BMI individuals. Targeted screening of older individuals with historical lack of educational opportunity, with a family history of T2DM even if of normal BMI may result in a significant benefit in the Pakistan population.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673776/pdf/xce-9-159.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38641604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region. 秘鲁地区公共部门卫生工作者脱氢表雄酮水平与心血管风险之间的关系

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-19 eCollection Date: 2021-03-01 DOI: 10.1097/XCE.0000000000000219

Ricardo J Rojas, Janett V Chávez-Sosa, Rosmery Gutierrez-Ajalcriña, Salomón Huancahuire-Vega

{"title":"Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region.","authors":"Ricardo J Rojas, Janett V Chávez-Sosa, Rosmery Gutierrez-Ajalcriña, Salomón Huancahuire-Vega","doi":"10.1097/XCE.0000000000000219","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000219","url":null,"abstract":"Alterations in dehydroepiandrosterone sulfate (DHEAS) levels have been shown to affect the cardiovascular system. This study examined the associations between DHEAS levels and cardiovascular risk in workers of a public hospital in Lima, Peru. The analytical cross-sectional study was conducted at the Hospital de Huaycán, Peru. The cardiovascular risk was assessed in health workers using the Framingham score and categorized into high and low cardiovascular risk groups, and then the DHEAS levels of both groups were compared. Two hundred ninety-six health workers were studied, 67.2% showed low cardiovascular risk, 22.3% intermediate and 10.5% high. DHEAS levels were lower in the high cardiovascular risk group (2156.9 vs 2814.6 ng/mL; P < 0.05) and showed negative association (prevalence rate ratio 0.14, 95% IC 0.04-0.53; P < 0.05) in multivariable analysis (P < 0.05). DHEAS, glycosylated hemoglobin, pulse pressure and mean arterial pressure show an independent association with high cardiovascular risk in a group of health workers. Additional variables should be considered for cardiovascular risk assessment.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901826/pdf/xce-10-51.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25406752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The epidemiological status, environmental and genetic factors in the etiology of Keshan disease. 克山病的流行病学现状、环境和遗传因素在病因中的作用。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-19 eCollection Date: 2021-03-01 DOI: 10.1097/XCE.0000000000000214

Chao Yan, Rong Luo, Feng Li, Mingjiang Liu, Jinshu Li, Wei Hua, Xiaoping Li

引用次数: 9

Peroxisome proliferator-activated receptor agonists and reversal of vascular degeneration through DNA repair, a step toward drug-induced regenerative medicine. 过氧化物酶体增殖物激活受体激动剂和通过DNA修复逆转血管变性，迈向药物诱导再生医学的一步。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-16 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000217

Peter Afdal, Habiba-Allah Ismail, Mirette Ashraf, Nada Hafez, Nardine Nasry, Nouran Hafez, Nourhan Youssef, Nourhan Samy, Rana Saeed, Antoine Fakhry AbdelMassih

{"title":"Peroxisome proliferator-activated receptor agonists and reversal of vascular degeneration through DNA repair, a step toward drug-induced regenerative medicine.","authors":"Peter Afdal, Habiba-Allah Ismail, Mirette Ashraf, Nada Hafez, Nardine Nasry, Nouran Hafez, Nourhan Youssef, Nourhan Samy, Rana Saeed, Antoine Fakhry AbdelMassih","doi":"10.1097/XCE.0000000000000217","DOIUrl":"10.1097/XCE.0000000000000217","url":null,"abstract":"Endothelial dysfunction with subsequent degeneration and vasoocclusive remodeling is the hallmark of many cardiovascular disorders including pulmonary vascular disease (PVD). To date, the available treatments slows disease progression but does not prevent deterioration. Reversing such pathologies would spare many patients risky surgeries and long waiting lists for a possible organ donor. Peroxisome proliferator-activated receptor agonists were first introduced as sole insulin sensitizers, however, there is increasing body of evidence that they have different actions on DNA which might help reverse vascular degeneration. This effect appears to be mainly achieved through enhancement of DNA damage responses (DDR). The aforementioned effect could offer new insights about repurposing drugs for achieving organ or tissue regeneration, an understudied field named drug-induced regenerative medicine.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673771/pdf/xce-9-128.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38631724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The FreeStyle Libre flash glucose monitoring system: how it has improved glycaemic control for people with type 1 diabetes in Eastern Cheshire, UK. FreeStyle Libre瞬时血糖监测系统:如何改善英国柴郡东部1型糖尿病患者的血糖控制。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-16 eCollection Date: 2020-12-01 DOI: 10.1097/XCE.0000000000000216

Ghasem Yadegarfar, Simon G Anderson, Zohaib Khawaja, Gabriela Cortes, Kathryn Leivesley, Ann Metters, Linda Horne, Tom Steele, Adrian H Heald

{"title":"The FreeStyle Libre flash glucose monitoring system: how it has improved glycaemic control for people with type 1 diabetes in Eastern Cheshire, UK.","authors":"Ghasem Yadegarfar, Simon G Anderson, Zohaib Khawaja, Gabriela Cortes, Kathryn Leivesley, Ann Metters, Linda Horne, Tom Steele, Adrian H Heald","doi":"10.1097/XCE.0000000000000216","DOIUrl":"https://doi.org/10.1097/XCE.0000000000000216","url":null,"abstract":"Introduction: Many people with type 1 diabetes continue to run high HbA1c levels with associated elevated risk of cardiovascular events and increased mortality. We describe here how use of the FreeStyle Libre flash monitor has improved the glycaemic control of many people with type 1 diabetes where the new technology has been intensively deployed.Methods: We report the outcomes of 92 consecutive adults (18 years of age or more) with type 1 diabetes who have begun using the FreeStyle Libre flash glucose monitor in East Cheshire, UK. Initiation was with education and support from one of the diabetes specialist nurses. An HbA1c of 60 mmol/mol (7.6%) was taken as the threshold for suboptimal glycaemic control.Results: The mean cohort age was 43 years for men and 39 years for women (overall range 17-83 years). In 92 consecutive users, HbA1c decreased by an average of 10.7 mmol/mol (0.98%) after 3 months, and by 16.1 mmol/mol (1.47%) after 6 months. There was also a narrowing of the distribution of HbA1c, with many fewer people running high HbA1c ≥80 mmol/mol (9.5%). After the 6-month follow-up, two 2/92 users did not wish to continue with the monitoring.Conclusion: Flash glucose monitoring has great potential for the management of type 1 diabetes in the adult population and improving metabolic control/quality of life for people across the world. The technology provides significantly more data than the intermittent results obtained by traditional subcutaneous blood glucose monitoring, which may not capture intervals of extreme variability or nocturnal events.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38641606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Is it infection or rather vascular inflammation? Game-changer insights and recommendations from patterns of multi-organ involvement and affected subgroups in COVID-19. 是感染还是血管炎症?来自COVID-19多器官受累模式和受影响亚群的改变游戏规则的见解和建议。

IF 2.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-11 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000211

Antoine Fakhry AbdelMassih, Aya Kamel, Fady Mishriky, Habiba-Allah Ismail, Layla El Qadi, Lauris Malak, Miral El-Husseiny, Mirette Ashraf, Nada Hafez, Nada AlShehry, Nadine El-Husseiny, Nora AbdelRaouf, Noura Shebl, Nouran Hafez, Nourhan Youssef, Peter Afdal, Rafeef Hozaien, Rahma Menshawey, Rana Saeed, Raghda Fouda

{"title":"Is it infection or rather vascular inflammation? Game-changer insights and recommendations from patterns of multi-organ involvement and affected subgroups in COVID-19.","authors":"Antoine Fakhry AbdelMassih, Aya Kamel, Fady Mishriky, Habiba-Allah Ismail, Layla El Qadi, Lauris Malak, Miral El-Husseiny, Mirette Ashraf, Nada Hafez, Nada AlShehry, Nadine El-Husseiny, Nora AbdelRaouf, Noura Shebl, Nouran Hafez, Nourhan Youssef, Peter Afdal, Rafeef Hozaien, Rahma Menshawey, Rana Saeed, Raghda Fouda","doi":"10.1097/XCE.0000000000000211","DOIUrl":"10.1097/XCE.0000000000000211","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is a serious illness that has rapidly spread throughout the globe. The seriousness of complications puts significant pressures on hospital resources, especially the availability of ICU and ventilators. Current evidence suggests that COVID-19 pathogenesis majorly involves microvascular injury induced by hypercytokinemia, namely interleukin 6 (IL-6). We recount the suggested inflammatory pathway for COVID-19 and its effects on various organ systems, including respiratory, cardiac, hematologic, reproductive, and nervous organ systems, as well examine the role of hypercytokinemia in the at-risk geriatric and obesity subgroups with upregulated cytokines' profile. In view of these findings, we strongly encourage the conduction of prospective studies to determine the baseline levels of IL-6 in infected patients, which can predict a negative outcome in COVID-19 cases, with subsequent early administration of IL-6 inhibitors, to decrease the need for ICU admission and the pressure on healthcare systems. Video abstract: http://links.lww.com/CAEN/A24.","PeriodicalId":43231,"journal":{"name":"Cardiovascular Endocrinology & Metabolism","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2020-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XCE.0000000000000211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38271997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Cardiovascular and cardiometabolic prevention: high-level priority in the era of COVID-19. 心血管和心脏代谢预防：COVID-19 时代的高度优先事项。

IF 1.3

Cardiovascular Endocrinology & Metabolism Pub Date : 2020-06-11 eCollection Date: 2020-09-01 DOI: 10.1097/XCE.0000000000000215

Devinder Dhindsa, Nathan D Wong, Laurence Sperling

引用次数: 0