2014 18th National Biomedical Engineering Meeting最新文献_第2页

Numerical analysis of spinal cord stimulation with a 2-electrode percutaneous lead 双电极经皮导联脊髓刺激的数值分析

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026382

Reyhan Zengin, N. G. Gencer, F. Kucukdeveci

引用次数: 4

Higuchi fractal dimension analysis of surface EMG signals and determination of active electrode positions 表面肌电信号的Higuchi分形维数分析及活性电极位置的确定

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026348

Çağdaş Topçu, Merve Bedeloglu, A. Akgul, Refik Sever, O. Ozkan, O. Ozkan, H. Uysal, O. Polat, O. H. Colak

引用次数: 2

Respiratory sound classification using perceptual linear prediction features for healthy - Pathological diagnosis 基于感知线性预测特征的呼吸声分类用于健康-病理诊断

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026343

Sezer Ulukaya, Y. Kahya

引用次数: 3

Determination of glucose and Hba1c values in blood from human breath by using Radial Basis Function Neural Network via electronic nose 电子鼻径向基函数神经网络测定人呼吸血液中葡萄糖和糖化血红蛋白

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026340

Hamdi Melih Saraoglu, Ali Osman Selvi

引用次数: 5

Engineering design of in vitro mono-culture model of blood-brain barrier and investigation of methotrexate permeability on the model 体外单培养血脑屏障模型的工程设计及甲氨蝶呤对模型渗透性的影响

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026360

M. Ozyurt, S. Dogan, S. Ozturk, S. I. Gurhan, A. Urkmez

{"title":"Engineering design of in vitro mono-culture model of blood-brain barrier and investigation of methotrexate permeability on the model","authors":"M. Ozyurt, S. Dogan, S. Ozturk, S. I. Gurhan, A. Urkmez","doi":"10.1109/BIYOMUT.2014.7026360","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2014.7026360","url":null,"abstract":"Blood-brain barrier (BBB) is a control mechanism that limits the diffusion of many substances to central nervous system through blood, and governs the nutrient diffusivity. This barrier is among the main risk factors for treatment of neurodegenerative diseases, because most drugs designed are protein based, and are either blocked by BBB, or lose their bioavailability significantly. In this study, an in vitro BBB model was designed for testing therapeutics for neurodegenerative diseases, and methotrexate drug permeability was investigated. In the BBB model design step, poly-caprolactone fiber surfaces were prepared by electrospinning to be used as support membrane for cells. The fiber morphology and sizes were determined using polarizing microscopy. Human umbilical vein endothelial cells (HUVEC) and C6 glioma cells were cultured on either side of this membrane. Model's proximity to in vivo models was tested by home-designed transendothelial electrical resistance measuring device; and nicotine was used as a positive control and albumin as a negative control. The effect of Methotrexate was determined indirectly by vitality test, MTT, for MCF-7 breast cancer cells seeded on the bottom of the well plates. The model's proximity to models in the literature and natural blood-brain barrier was specified relatively.","PeriodicalId":428610,"journal":{"name":"2014 18th National Biomedical Engineering Meeting","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123580130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance analysis of histogram-threshold method for cancer detection 直方图阈值法在癌症检测中的性能分析

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026356

Gamze Koç, Y. D. Gokdel, B. Sarıoǧlu

引用次数: 0

Early diagnosis of acute coronary syndromes with automatic ST/T classifier ST/T自动分类器对急性冠脉综合征的早期诊断

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026388

M. B. Terzi, O. Arikan, A. Abacı, Mustafa Candemir, Mehmet Dedoglu

引用次数: 10

Development of a biomechanical model for the analysis of the wrist extension and flexion movement 腕部伸展和屈曲运动生物力学模型的建立

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026371

Kasim Serbest, O. Eldogan, M. Yıldız, M. Çilli

引用次数: 0

Investigation of central nervous system neurons under mechanical strain: An in vitro traumatic brain injury model 机械应变下中枢神经系统神经元的研究:体外创伤性脑损伤模型

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026384

O. Duman, Cenk Celik, M. Sarıkanat, A. Urkmez

{"title":"Investigation of central nervous system neurons under mechanical strain: An in vitro traumatic brain injury model","authors":"O. Duman, Cenk Celik, M. Sarıkanat, A. Urkmez","doi":"10.1109/BIYOMUT.2014.7026384","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2014.7026384","url":null,"abstract":"Effects of mechanical loading on development of central nervous system (CNS) cells and neurite extension have been recognized recently. Effects of loading are very complicated, since until a threshold, tension plays a positive role while after the threshold value, it is degenerative. The situation gets more complicated since CNS is made up of several different cell types that respond to various loads differently. There are some mechanical trauma models in the literature, but they usually employ hard and two dimensional culture substrates, which fail to mimic the natural niche of the cells. The aim of this work is to create an experimental model that can mimic the physiological habitat and normal loading conditions, and investigate the responses of CNS cells in response to different mechanical stimuli and strains, and therefore evaluate the effects of mechanical stress on cell development, neurite extension and degeneration, in order to be used in therapeutic investigations for neurodegenerative diseases. Electrospun poly-caprolactone (PCL) scaffolds were used as tissue engineering scaffolds, and B35 central nervous system neuron cell line was employed. Effects of mechanical strain on cell morphology, neurite extension and cytoskeleton, and after the threshold value, on apoptosis have been examined in morphological and molecular level.","PeriodicalId":428610,"journal":{"name":"2014 18th National Biomedical Engineering Meeting","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127393002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between Hurst exponent and Poincaré parameters in non-linear signal analysis 非线性信号分析中Hurst指数与poincarcarr参数的相关性

2014 18th National Biomedical Engineering Meeting Pub Date : 2014-10-01 DOI: 10.1109/BIYOMUT.2014.7026336

G. Ertas, A. U. Keskin

引用次数: 0