Sensors and Actuators B: Chemical最新文献

{"title":"Interface Engineering of MXene using ZSM-5 Molecular Sieve: Atomic-Level Charge Transfer Pathways for Ultra-Sensitive NO2 Detection","authors":"Shenghui Xia, Chen Chen, Jinhong Liu, Yu Zhang, Hui Zhang, Thomas Thundat, Ajit Khosla","doi":"10.1016/j.snb.2025.138870","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138870","url":null,"abstract":"Nitrogen dioxide (NO₂) is a highly toxic air pollutant that endangers human health, environmental sustainability, and ecosystems. To address this issue, we designed an inorganic heterogeneous interface by integrating ZSM-5 molecular sieves with MXene via a facile synthesis route. This unique architecture synergizes the dual cross-channel framework of ZSM-5 and the high electrical conductivity and abundant surface functional groups of MXene. This combination greatly enhances electron transfer kinetics, interfacial NO₂ adsorption, and gas sensing properties. The optimized MXene/ZSM-5 nanocomposite achieves an ultra-low NO₂ detection limit of 1 ppm. Its response is 79.78% higher than that of original MXene. The nanocomposite also exhibits excellent stability and significant anti-interference properties. Correlation studies confirm consistent performance across humidity and atmospheric conditions. Density functional theory (DFT) calculations elucidated the charge transfer pathways and adsorption mechanisms at the atomic level that enhance sensitivity. By pioneering the MXene/ZSM-5 interface and systematically investigating its gas interaction kinetics, this work provides fundamental insights for designing next-generation MXene-based gas sensors.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"1 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-metal nanozyme loaded (Zr/Ce) UiO-66 driven self-cascade catalysis nanoreactor based on split aptamer for sensitive detection of pathogenic bacteria","authors":"Yang Song, Guoyang Xie, Luyang Zhao, Yi Zhao, Hengyi Xu","doi":"10.1016/j.snb.2025.138871","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138871","url":null,"abstract":"Pathogenic bacteria pose a significant impact on human and environmental health. Therefore, establishing a rapid and sensitive method for detecting these bacteria is urgent. In this study, a self-cascade catalysis nanoreactor based on split aptamers (SPA) was developed for the sensitive detection of <em>E. coli</em> O157:H7, enabling a self-powered H₂O₂ strategy and improved convenience. This approach employed (Zr/Ce) UiO-66 anchored with an AuRhPt trimetallic nanozyme. The incorporation of Ce enhances the specific surface area and catalytic activity of Zr UiO-66. The AuRhPt@(Zr/Ce) UiO-66 nanozyme exhibits multiple catalytic activities, such as glucose oxidase (GOx) and peroxidase (POD) activities, enabling the development of a self-powered H₂O₂ strategy. Subsequently, the aptamer was split into two shorter fragments to minimize steric hindrance, reduce costs, and achieve high performance. A self-cascade catalysis nanoreactor was developed using a split aptamer recognition and assembly strategy for the rapid and sensitive detection of <em>E. coli</em> O157:H7 in different real samples. The linear range for <em>E. coli</em> O157:H7 was 10¹–10⁵ CFU/mL in lake water, lettuce, and milk samples, with a limit of detection (LOD) of 10¹ CFU/mL and recoveries ranging from 81% to 117%. Consequently, this self-cascade catalysis nanoreactor is well-suited to the sophisticated detection requirements of diverse samples and shows significant promise as a highly sensitive and efficient approach for identifying other targets.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"4 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Portable histone assay technology (PHAST) for the sample-to-answer detection of circulating histones in whole blood","authors":"Rachel L. Warren, John R. Rzasa, Zehra F. Syeda, Alexander R. Pueschel, Ian M. White","doi":"10.1016/j.snb.2025.138848","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138848","url":null,"abstract":"Circulating histones are a potential biomarker for organ failure, organ transplant rejection, and sepsis. There is a need for point-of-care detection of histones in patient samples to enable diagnostics in the emergency department (sepsis), military field hospitals (trauma-induced organ failure), and at home (transplant rejection). For these applications, it is necessary to detect histones directly from whole blood samples without any intermediate steps and with low-cost portable instrumentation. Here we introduce portable histone assay technology (PHAST), an assay and a low-cost handheld instrument for the sample-to-answer detection of histones directly from blood samples. The assay utilizes a DNA-based FRET reporter molecule to enable direct detection of histones in a single step, while anti-red-blood-cell magnetic beads in combination with a moveable magnet in the handheld instrument remove the red blood cells prior to the fluorescence measurement. Using this novel approach, we detect clinically relevant concentrations of histones spiked into whole blood in under 20<!-- --> <!-- -->minutes.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"59 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-of-care testing of hyaluronidase in the urine using commercial pregnancy test strips as readout","authors":"Jing Yang, Zhonghui Chen, Yue Lin, Cuiying Lin, Fang Luo, Bin Qiu, Jian Wang, Zhenyu Lin, Huixing Chen","doi":"10.1016/j.snb.2025.138851","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138851","url":null,"abstract":"Elevated hyaluronidase (HAase) concentration has been found in the urine samples of the patients with bladder cancer and development of simple but sensitive detection methods for HAase is important for related disease screening. Pregnancy test strips (PTSs) is one of the most common portable and inexpensive household testing strips, which has been used to measure human chorionic gonadotropin (HCG) in urine sample for pregnancy test. In this study, a portable biosensor has been developed for HAase using PTSs as detection device. HCG was embedded in a hydrogel format through the cross-linking of hyaluronic acid (HA) and polyethylenimine (PEI). The presence of HAase can digest HA in the hydrogel and results in the releasing of HCG, which can be detected by a PTS easily. The color changing of the test line (T line) indicates the existence of the target object and the depth of color can be used for semi-quantitative detection of the target concentration. The ImageJ software was used to extract the RGB value of the color of T line. The different of the RGB value (ΔRGB) at present and absent of target has a strong linear correlation with the HAase concentration between 1<!-- --> <!-- -->U/mL and 100<!-- --> <!-- -->U/mL, with a limit of detectionof 0.27<!-- --> <!-- -->U/mL (S/N = 3). The proposed method was used to detect HAase in urine samples from non-pregnancy healthy individuals and patients diagnosed with bladder cancer as a demonstration.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"61 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calibration-free quartz tuning fork enhanced laser spectroscopy for trace gas detection","authors":"Linguang Xu, Qiannan Cai, Dingli Xu, Haoyue Wu, Gang Zhang, Qiang Ge, Jingsong Li","doi":"10.1016/j.snb.2025.138854","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138854","url":null,"abstract":"In this paper, a calibration-free quartz tuning fork enhanced laser spectroscopy (QTFELS) gas sensing system is presented for trace gas detection. To demonstrate the proposed gas detection technique, a near-infrared distributed feedback (DFB) semiconductor laser operating at 1653<!-- --> <!-- -->nm was combined with a 30-meter multi-pass cell was specifically employed for CH₄ gas measurements using the first harmonic-normalized second harmonic signal of wavelength modulation spectroscopy (WMS-2<em>f</em>/1<!-- --> <em>f</em>). A standard spectral model and least-squares-based calibration-free algorithm were proposed for real-time inversion of gas concentrations. This algorithm is designed to compensate for signal amplitude fluctuations in QTF detectors induced by ambient light intensity variations. Experimental results demonstrate that the 2<!-- --> <em>f</em>/1<!-- --> <em>f</em> signal ratio exhibits an 8.31-fold enhancement in response sensitivity for concentration retrieval compared to the standalone 2<!-- --> <em>f</em> signal. The CH₄ detection system achieves a maximum error below 3.3%, with its precision reaching 20 ppb at an optimal Allan deviation integration time of 308<!-- --> <!-- -->s. Finally, the proposed gas sensing system was employed for approximately 24-hour long-term measurements of ambient CH₄ concentrations outside the laboratory, demonstrating the sensor's exceptional monitoring performance.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"91 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PTADA: An unsupervised domain-adversarial regression algorithm for sensor drift in mixed gas scenarios","authors":"Xinpeng Cui, Xiaoran Huang, Xinyu Zhang, Peter Feng, Lidan Wang, Shukai Duan, Xiaoyan Peng","doi":"10.1016/j.snb.2025.138855","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138855","url":null,"abstract":"Compared to single-gas detection, regression prediction for mixed gas is more challenging, due to the feature diversity among different gas components and distribution discrepancy between source and target domains that caused by sensor drift effect. To address these challenges, we propose an unsupervised adversarial domain adaptation neural network called Progressive dual-stream Temporal network with Attention for Domain Adaptation (PTADA), offering an effective drift compensation solution for mixed gas regression tasks through adversarial learning. PTADA employs a multi-scale modeling approach to progressively extract local and global dependencies from temporal gas data, constructing a hierarchical temporal dependency structure and enhancing feature representation. Additionally, PTADA employs Multi-Kernel Maximum Mean Discrepancy (MK-MMD) for regularization to boost domain adaptation. Furthermore, to address the issue of sample imbalance in the concentration data, we designed a hybrid compressed focal loss function (H-Focal Loss) that combines linear error and logarithmic error. We evaluated PTADA on a self-collected H₂S–SO₂ mixed gas drift dataset, focusing on the novel and challenging task of regression-based drift compensation for mixed gases. The experimental results show that PTADA achieved R² values of 0.924 and 0.937 for H₂S and SO₂, respectively, outperforming traditional models and other drift compensation methods (such as Informer, SWD, and ADDA), which highlights its significant advantages in regression tasks under mixed gas drift conditions. Furthermore, noise resistance and sensor failure experiments verified the robustness of PTADA, and additional tests on public dataset and other mixed gas dataset demonstrated its strong generalization capability.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"65 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A reversible color switching nano-sensing label based on polyvinyl alcohol-acidochromic chitosan (PVA-ACS) for enhanced recognition of meat freshness","authors":"Mengjie Li, Tingting Han, Huiwen Liu, Juan Xu, Chong Sun, Yongzhi Zhu, Weiming Xu, Daoying Wang","doi":"10.1016/j.snb.2025.138858","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138858","url":null,"abstract":"In this work, an intelligent and sensitive polyvinyl alcohol-acidochromic chitosan (PVA-ACS) nano-sensing label was developed for visually monitoring meat freshness. Based on the synthesis of 1-hydroxy-4-[4-(ethylsulfurate sulfonyl)-phenylazo]-naphthalene (HESPN), ACS was prepared through hydrogen bonding between the sulfonic acid groups in HESPN structure and the hydroxyl groups in chitosan (CS). Herein, PVA was used as the functional matrix and electrospinning technology was employed in this process. The chemical structure, surface morphology, mechanical properties, hydrophilicity, thermal stability, and biocompatibility of PVA-ACS nano-sensing label were investigated. Moreover, the PVA-ACS nano-sensing label exhibited sensitive color responsiveness and reversible color switching, and the properties enabled the naked-eye inspection of meat freshness during production, processing and transportation. Furthermore, a strategy incorporated the nano-sensing labels with a smartphone was developed to record color information in conjunction with the color recognition software (ColorColl). This work provided a valuable perspective for real-time freshness monitoring with high satisfaction and efficiency, opening new possibilities for meat quality grading.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"87 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Accurate and Autonomous Programmable Platform for Providing Air Pollution Data Services to Drivers and the Public – Polish Case Study","authors":"Dominik Grochala, Anna Paleczek, Sławomir Gruszczynski, Marek Wójcikowski, Bogdan Pankiewicz, Anna Pietrenko-Dabrowska, Sławomir Koziel, Tuan-Vu Cao, Artur Rydosz","doi":"10.1016/j.snb.2025.138859","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138859","url":null,"abstract":"Nitrogen dioxide (NO₂) is a well-known air pollutant, mostly elevated by car traffic in cities. To date, small, reliable, cost-efficient multipollutant sensors with sufficient power and accuracy for community-based atmospheric studies are still lacking. The HAPADS (highly accurate and autonomous programmable platforms for providing air pollution data services) platforms, developed and tested in real conditions, can be a possible approach to solving this issue. The developed HAPADS platforms are equipped with three different NO₂ sensors (7E4-NO2-5, SGX-7NO2, MICS-2711 MOS) and a combined ambient air temperature, humidity, and pressure sensor (BME280). The platforms were tested during the driving test, which was conducted across various roads, including highways, expressways, and national and regional routes, as well as major cities and the countryside, to analyse the environmental conditions as much as possible (Poland, 2024). The correlation coefficient <em>r</em> was more than 0.8, and RMSE (root mean squared error) was in the 3.3-4.3 μg/m³ range during the calibration process. The results obtained during the driving tests showed R² of 0.9-1.0, which proves the ability of HAPADS platforms to work in the hard environmental conditions (including high rain and snow, as well as sun and a wide range of temperatures and humidity).","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"28 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated microfluidic dynamic potential-modulated SERS chip with high sensitivity and self-cleaning","authors":"Yuan Gan,&nbsp;Shen Shen,&nbsp;Ning Wang,&nbsp;Jie Zhang","doi":"10.1016/j.snb.2025.138840","DOIUrl":"10.1016/j.snb.2025.138840","url":null,"abstract":"<div><div>Surface-enhanced Raman scattering (SERS) technology faces several challenges in real-world applications, including low sensitivity, irreversible contamination of the substrate leading to poor cyclic stability, and difficulties in achieving integration of complex detection processes. To address these challenges, we propose a microfluidic-SERS integrated detection chip with dynamic potential modulation, enabling a complete “detection–self-cleaning–re-detection” closed-loop operation. Firstly, a high-sensitivity core-shell Ag@SiO₂ substrate was prepared using chemical reduction, achieving a detection limit of 10⁻¹² mol/L for Rhodamine 6 G (R6G) (AEF = 5.7 × 10⁹). Plasma surface cleaning was then applied to bond polydimethylsiloxane (PDMS) microfluidic channels with screen-printed electrodes (SPEs), resulting in the construction of a microfluidic-SERS chip with dynamic potential modulation. By applying a positive potential (+2.0 V/10 s), target molecules were desorbed from the metal nanoparticle gaps on the SERS substrate, and a metastable metal oxide layer of a certain thickness was formed. Subsequently, a negative potential (−1.2 V/15 s) was applied to remove part of the metal oxide layer, realizing in-situ regeneration of Raman hotspots and rapidly driving probe molecule enrichment. After eight cycles of detection, the signal strength remained high. Additionally, this platform can precisely identify multi-molecule mixtures (R6G/CV/MG) and has been successfully applied to the detection of uric acid molecules. Its on-site detection capability was further validated in a portable system, providing an innovative solution for rapid detection in complex real-world environments.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"447 ","pages":"Article 138840"},"PeriodicalIF":3.7,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compact mid-infrared tunable interband-cascade laser-based spectrometer: Characterization and outlook for Amide-I region chemical sensing","authors":"Mehmet Can Erdem ,&nbsp;Polina Fomina ,&nbsp;Pranish Karki ,&nbsp;Antoni Femenias ,&nbsp;Uladzislau Blazhko ,&nbsp;Julian Scheuermann ,&nbsp;Boris Zimmermann ,&nbsp;Michael Angelo Amith Fenelon ,&nbsp;Andrea Teuber ,&nbsp;Maren Anna Brandsrud ,&nbsp;Robert Weih ,&nbsp;Johannes Koeth ,&nbsp;Boris Mizaikoff ,&nbsp;Achim Kohler","doi":"10.1016/j.snb.2025.138841","DOIUrl":"10.1016/j.snb.2025.138841","url":null,"abstract":"<div><div>This paper presents the development and evaluation of a compact mid-infrared (MIR) spectroscopy sensor system based on a tunable interband-cascade laser (tICL), intended for portable chemical sensing in field and industrial applications. The study focuses on the implementation, optimization and characterization of the optical system to provide an in-depth performance assessment of a customized spectrometer operating within a subset of the Amide-I region covering 1692 cm⁻¹ to 1640 cm⁻¹ (5.91 µm to 6.10 µm), using a novel tICL MIR laser. We performed a systematic evaluation of individual wavenumbers generated by the tICL laser to assess each single emission wavelength's performance. Aqueous ethanol and formic acid solutions at varying concentrations were utilized as test analytes to gauge the analytical capabilities of this system. We examined the signal strength and variability across all emission wavelengths by studying the absorbance values' dependence on various analyte mixture concentrations throughout the entire spectral range and find that most emission points have stable intensities. The performance of the new system was then benchmarked with a conventional FTIR spectrometer. The results demonstrate that compared to the reference FTIR spectrometer, the tICL laser-based system also achieves consistent trends and comparable results. Furthermore, it offers additional potential for miniaturization and feasibility for lab-on-a-chip applications. These findings highlight the potential of tICL-based MIR spectroscopy as a compact and highly sensitive tool for targeted applications where portable, narrow-range MIR sensing is sufficient, making it well-suited for field and industrial use cases.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"447 ","pages":"Article 138841"},"PeriodicalIF":3.7,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}