Cuadernos de Bioetica最新文献_第9页

[Case: bioethical disputes of the donations of the pharmaceutical companies to the health centers]. [案例:制药公司向医疗中心捐赠的生物伦理争议]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.81

Antonio Pardo

引用次数: 0

[Reflections on the meaning of pain, suffering and death]. [对痛苦、苦难和死亡意义的思考]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.77

María Luisa Pro Velasco

引用次数: 0

[From transgenesis to gene edition. Bioethical and applied considerations]. 从转基因到基因编辑。生物伦理和应用方面的考虑]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.78

Nicolás Jouve de la Barreda

{"title":"[From transgenesis to gene edition. Bioethical and applied considerations].","authors":"Nicolás Jouve de la Barreda","doi":"10.30444/CB.78","DOIUrl":"https://doi.org/10.30444/CB.78","url":null,"abstract":"Transgenesis is a parcel of biotechnology that allows the introduction of genetic information not proper to the genome of living beings, apart from the mechanisms of natural genetic exchange. This made possible to address important applications in bacteria, animals and plants with significant benefits in health, food and environmental aspects. Since its origin, the production of genetically modified organisms (GMOs) caused some controversy due to the possible negative influence of these organisms or their derived products on health and the environment. Over time, genetic modification techniques have renewed, giving way to others of greater precision, simplicity and safety. Currently the CRISPR-Cas9 technique is widely used, which allows to edit, modify or eliminate specific DNA sequences, with multiple applications in the same fields of transgenesis, but adding greater simplicity, security and lower cost. This work presents the main techniques, applications and ethical implications of using these methods and their perspectives in an ever-evolving world. The bacteria for obtaining products of pharmacological interest, new varieties of cultivated plants of higher production, more resistance to growth limiting agents and better nutritional quality and domestic animals modified genetically, offer a set of advantages needed to address the global challenges that affect the lives of many people around the world.","PeriodicalId":42510,"journal":{"name":"Cuadernos de Bioetica","volume":"31 103","pages":"387-401"},"PeriodicalIF":0.5,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38762049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Knowledge of the Assistance Bioethics Committee (ABC) between the general hospital health professionals]. [知识援助生物伦理委员会(ABC)之间的综合医院卫生专业人员]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.75

Francisco Pons Valls, Eufemia Marcos González, Enrique Vera-Remartínez, M Desamparados Bernat Adell, Julio García-Guerrero

{"title":"[Knowledge of the Assistance Bioethics Committee (ABC) between the general hospital health professionals].","authors":"Francisco Pons Valls, Eufemia Marcos González, Enrique Vera-Remartínez, M Desamparados Bernat Adell, Julio García-Guerrero","doi":"10.30444/CB.75","DOIUrl":"https://doi.org/10.30444/CB.75","url":null,"abstract":"To show hospital health professionals' knowledge on ABC. Observational, descriptive, transversal and analytical research using questionnaires designed ad hoc. Comparative statistical analysis applying Ji-square by Pearson and Fisher tests. Binary logistic regression model to determine the odd ratios (O.R) having education level and sex as independent variables. A 4% accuracy was accepted, as well as a confidence Interval of 95% and a p value inferior to 0.05. The data was processed by IBM SPSS Statistics v.20 software. Required sample of 351 professionals (108 doctors and other related graduate; 144 nurses and 99 clinical assistants (TCAE)). 276 participants (78,6%; IC95%: 74,0-82,2); of which 84 doctors (77,8%; IC95%: 68,8-85,2); 120 nurses (83,3%; IC95%: 76,2-89,0) y 71 TCAE (71,7%; IC95%: 61,7-80,3), predominantly women (194, 70,3%). 228 (82,6%) were aware of the existence of ABC. Both doctors and nurses had more knowledge of ABC than clinical assistants (p 0,0001 for both), however there was not significative difference between doctors and nurses (p=0,836; OR:0,901; IC95%: 0,334-2,228). 124 (45,1%) knew the functions of ABC, with doctors displaying more knownledge than both nurses and clinical assistants (p=0,002 and p 0,0001 respectively) and nurses showing more familiarity than clinical assistants (p=0,008). 129(47,6%) communicated ethical conflicts, showing no significative difference between doctors and nurses (p=0,119). However, clinical assistants displayed different behabiour than the other two groups in this regard (p 0,0001 and p=0,001 respectively). Of all, 47 (22,4%) communicated they had ethical conflicts regarding the beginning and end of life. The knowledge on the existence of the ABC is high, however there is poor knowledge around its functions. Among health professionals, doctors and nurses know him better than TCAE. Matters related with the beginning and end of life cause most of ethical conflicts.","PeriodicalId":42510,"journal":{"name":"Cuadernos de Bioetica","volume":"31 103","pages":"357-366"},"PeriodicalIF":0.5,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38762045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Persons in prostitution situation. Disposition of the own body or human subjectivity as object?] [处于卖淫状况的人。是把自己的身体还是把人的主体性作为客体来处理?]

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.72

Ian Henríquez Herrera, Pamela Cajales Macuer

引用次数: 0

[Epigenetics. Mechanism and significance in gene regulation]. 表观遗传学。基因调控的机制及意义[j]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.79

Nicolás Jouve de la Barreda

{"title":"[Epigenetics. Mechanism and significance in gene regulation].","authors":"Nicolás Jouve de la Barreda","doi":"10.30444/CB.79","DOIUrl":"https://doi.org/10.30444/CB.79","url":null,"abstract":"Epigenetics deals with the study of structural modifications in the regions of the genome, by methylation of DNA or chromosomal histones, or other mechanisms that affect the expression of genes without altering the base composition of DNA. Cell differentiation, which is established in embryonic development from blastocyst status, is the consequence of differential cell reprogramming, based on programmed epigenetic modifications, which establish differences in the epigenome of cells and tissues. Maternal and paternal genomes of the gametes have genomic imprinting differences due to DNA methylation or other epigenetic modifications established in the germinal cells during gametogenesis. Maternal and paternal parental genomes present differences of genomic imprinting, which are established by DNA methylation or other epigenetic modifications during embryonic development, in the primordial germ cells. Unscheduled epigenetic modifications may also occur under the influence of uncontrolled environmental factors, which can lead to health disturbances. However, all epigenetic modifications are erased after fertilization and those affecting the germ line of the embryo or fetus during their development are not inherited beyond the second generation, - F2 -. Epigenetics should not be considered a new type of inheritance with transgenerational consequences, but as a set of mechanisms related to genetic regulation.","PeriodicalId":42510,"journal":{"name":"Cuadernos de Bioetica","volume":"31 103","pages":"405-419"},"PeriodicalIF":0.5,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39097725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Case: bioethical disputes of the donations of the pharmaceutical companies to the health centers]. [案例:制药公司向医疗中心捐赠的生物伦理争议]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.80

Abel González-González

引用次数: 0

[May '68 revolution and gender post-feminism]. [五八革命与后女权主义性别]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.70

Ángela Aparisi Miralles

引用次数: 0

[Action before ethical dilemmas in the consultation after divorce. Role of the minor according to age and level of maturity]. 在离婚后的道德困境咨询前的行动。未成年人的角色(根据年龄和成熟程度)。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-09-01 DOI: 10.30444/CB.71

Mariano Leal Hernández, Javier Navarro-Zaragoza, María Falcón, Francisco Carrillo Navarro, Aurelio Luna

{"title":"[Action before ethical dilemmas in the consultation after divorce. Role of the minor according to age and level of maturity].","authors":"Mariano Leal Hernández, Javier Navarro-Zaragoza, María Falcón, Francisco Carrillo Navarro, Aurelio Luna","doi":"10.30444/CB.71","DOIUrl":"https://doi.org/10.30444/CB.71","url":null,"abstract":"Lately, number of divorces is increasing, nevertheless, a parents' divorce can become a traumatic problem for paediatric patients. Consequently, the aim of this study was to analyze the ethical conflicts that appear in the relationship between physician/parents/son/daughter, and more specifically those that a divorce generates. A descriptive study was developed through a survey composed by 39 items. Previously, an exhaustive bibliographic analysis was carried out. Our results show that only 35% of paediatricians interviewed have been educated in bioethics although this issue is important in daily practice. Other items show that 57,5% would not cancel a pharmacological treatment in order to improve quality of life. Also, they would react against a wrong parents' decision (82,5%). They give low value to the minor`s decision (6,05%), and rarely inform exclusively to adolescents (5%). In contrast, paediatricians sometimes ask to adolescents (20%) in first place and involved them to decide in 90% of cases. Besides, there are differences in the relation with fathers and mothers, 17,5% of mothers are informed exclusively, a fact that never happens with fathers. Ethics has an intrinsic value very important in daily clinical decisions in order to respect the rules and to adapt them to the situation of every paediatric patient. When an important ethical conflict become, as a divorce is, it is essential to know who must be informed and the rights everyone has to make a decision. It is complicated to the paediatricians yet to develop 41/2002 law for Patient's autonomy.","PeriodicalId":42510,"journal":{"name":"Cuadernos de Bioetica","volume":"31 103","pages":"309-317"},"PeriodicalIF":0.5,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38763133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[UNESCO on COVID-19: Ethical Guidelines for a Global Response]. [教科文组织关于COVID-19:全球应对的道德准则]。

IF 0.5

Cuadernos de Bioetica Pub Date : 2020-05-01 DOI: 10.30444/CB.69

Luis Vivanco

引用次数: 1