Medical Bulletin of Sisli Etfal Hospital最新文献

{"title":"Preoperative Systemic Coagulation Inflammation Index may be a Predictor of Worse Outcomes After Carotid Endarterectomy.","authors":"Mesut Engin, Orhan Guvenc, Ahmet Kagan As, Ufuk Aydin, Yusuf Ata, Senol Yavuz","doi":"10.14744/SEMB.2026.62558","DOIUrl":"10.14744/SEMB.2026.62558","url":null,"abstract":"<p><strong>Objectives: </strong>Stroke is a significant disease associated with high mortality and morbidity rates, and carotid artery stenosis (CAS) is one of its most important causes. Although endovascular applications have increased in the treatment of CAS, carotid endarterectomy (CEA) surgery remains prominent. The systemic coagulation inflammation index (SCII) has emerged as an important marker indicating coagulation and inflammatory status. In this study, we aimed to investigate the effect of SCII values on worse outcomes during 30-day follow-up in patients who underwent CEA.</p><p><strong>Methods: </strong>This retrospective study consecutively included patients who underwent carotid endarterectomy at our clinic between January 1, 2020, and June 1, 2025. Patients who did not develop worse outcomes within the first 30 days after surgery were assigned to Group 1, and those who did were assigned to Group 2. Worse outcomes in the study were defined as stroke, myocardial infarction, and death.</p><p><strong>Results: </strong>A total of 594 patients underwent elective CEA surgery. The 546 patients in Group 1 and the 48 patients in Group 2 had median ages of 71 (44-88) and 69 (41-91) years, respectively (p=0.185). As a result of the multivariate analysis, the presence of coronary artery disease (OR: 1.690, 95% CI: 1.210-1.984, p=0.032) and high SCII values (OR: 1.780, 95% CI: 1.270-2.894, p<0.001) were determined as independent predictors of worse outcomes after CEA surgery.</p><p><strong>Conclusion: </strong>Our results indicated that high SCII values were associated with worse outcomes within 30 days after CEA. In patients undergoing CEA, SCII values can be calculated preoperatively to identify at-risk patient groups; therefore, measures can be taken for patient management and follow-up in the postoperative period.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"180-187"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148424944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Percutaneous Nephrostomy on Pain, Quality of Life, Family Burden, and Depressive Symptoms: A Prospective Observational Study.","authors":"Bekir Demirtas, Ahmet Tahra, Ozgur Arikan, Ahmet Keles, Muhammet Cicek, Ilkin Hamid-Zada, Mammad Khalilov, Umut Percem Orhan Soylemez, Asif Yildirim","doi":"10.14744/SEMB.2026.34032","DOIUrl":"10.14744/SEMB.2026.34032","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the impact of percutaneous nephrostomy (PN) on family burden, health-related quality of life (HRQoL), depressive symptoms, and pain, and to identify predictors of postoperative change.</p><p><strong>Methods: </strong>In this prospective study, 119 patients undergoing PN for obstructive uropathy were assessed before and after PN using the Visual Analog Scale (VAS), Beck Depression Inventory (BDI), EQ-5D-3L sum score, and Family Reported Outcome Measure-16 (FROM-16). Pre- and post-procedure differences were analyzed using the Wilcoxon signed-rank test, and multivariable linear regression was used to identify predictors of change (p<0.05).</p><p><strong>Results: </strong>The mean age was 61.7 years, and 64.7% of the patients were male. Malignancy was the most common etiology, followed by stone disease and benign strictures. All outcomes deteriorated after PN: FROM-16 increased from 7.39 to 15.87, EQ-5D-3L sum score from 7.45 to 13.71, BDI from 12.97 to 17.92, and VAS from 1.22 to 5.23 (all p<0.001). Malignancy, ureteral stricture, and infection were associated with smaller increases in family burden. Spousal caregiving was associated with greater HRQoL deterioration (p=0.020), whereas infection predicted less worsening. Older age was associated with greater increases in BDI, while longer marriage duration and unemployment were associated with smaller BDI changes (p<0.05). Pain worsening was less pronounced in male patients and those with higher education levels (p<0.05).</p><p><strong>Conclusion: </strong>Although PN relieves obstruction, it is associated with significant deterioration in psychosocial outcomes. Psychosocial screening and caregiver support should be integrated into PN care pathways to protect patient-centered outcomes.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"154-161"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal Invasive Approach in Severe Tracheobronchomalacia: Türkiye's First Case of Vats Tracheobronchoplasty.","authors":"Melike Ulker, Aysegul Ciftci, Ali Cevat Kutluk, Volkan Erdogu, Muzaffer Metin","doi":"10.14744/SEMB.2025.99422","DOIUrl":"10.14744/SEMB.2025.99422","url":null,"abstract":"<p><p>Tracheobronchomalacia is an expiratory collapse of the posterior wall of the trachea and at least one of the main bronchi. It may be idiopathic or may develop due to secondary causes. It results in a slowing of dynamic airflow and clinically presents with dyspnea, cough, and pneumonia. Although tracheal stents provide temporary relief in treatment, considering the problems encountered during the chronic phase, endobronchial therapy does not offer a long-term solution. Tracheobronchoplasty is a surgical treatment option. Examination of the few cases reported in the literature shows that, in centers with adequate video-assisted thoracoscopic surgery (VATS) experience, this procedure, which is frequently performed via right thoracotomy, can be effectively performed using minimally invasive techniques. A 66-year-old male patient presented with dyspnea. Severe tracheomalacia was detected, and tracheoplasty was performed using VATS. The present study aims to describe the first VATS tracheobronchoplasty procedure in Türkiye.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"279-282"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148424636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Antimicrobial Activity of Five Turkish Honey Types Against Otitis Externa Pathogens: A Comparative Study.","authors":"Serdal Celik, Hamdi Sirac Gundogdu, Nihat Arda Buyukasik, Muhammed Yasir Gumustas, Merve Ozmen, Ayten Guner Atayoglu, Mücahide Esra Kocoglu, Mahmut Tayyar Kalcioglu","doi":"10.14744/SEMB.2026.45228","DOIUrl":"10.14744/SEMB.2026.45228","url":null,"abstract":"<p><strong>Objectives: </strong>The global rise of antimicrobial resistance underscores the urgent need for alternative therapeutic agents for common infections such as otitis externa. This study aimed to investigate and compare the in vitro antimicrobial activity of five Turkish honey types-thyme, pine, linden, sunflower, and lavender-against eight microorganisms commonly associated with otitis externa.</p><p><strong>Methods: </strong>Honey samples were collected from certified Turkish beekeepers and analyzed for their physicochemical and biochemical properties. Antimicrobial activity was assessed using the broth microdilution method in line with CLSI guidelines. The tested microorganisms included <i>Pseudomonas aeruginosa</i> (ATCC and clinical isolate), <i>Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus faecium, Candida albicans</i>, and <i>C. tropicalis</i>. Minimum inhibitory concentrations (MICs) were determined to evaluate antibacterial efficacy.</p><p><strong>Results: </strong>Thyme honey showed the broadest spectrum of antimicrobial activity (62.5%), with particularly low MICs against <i>P. aeruginosa</i>. Linden and lavender honey inhibited 50% of the tested organisms, with lavender honey being the most effective against <i>S. aureus</i>. Pine honey demonstrated moderate efficacy (25%), whereas sunflower honey showed minimal antimicrobial activity (12.5%). Notably, all honeys were ineffective against both <i>Candida</i> species at the tested concentrations. A strong correlation was observed between total phenolic content and antimicrobial effect, with thyme honey having the highest phenolic and antioxidant values.</p><p><strong>Conclusion: </strong>Turkish honey, especially thyme honey, demonstrates promising antibacterial activity against otitis externa pathogens. These findings suggest potential for honey-based adjunctive therapies in managing bacterial ear infections, particularly amid rising antibiotic resistance. However, the lack of antifungal efficacy highlights limitations in fungal otitis cases.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"237-243"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148424671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auricular Relapsing Polychondritis in a Patient With Crohn's Disease: A Case Report.","authors":"Beyza Nur Ulas, Belit Merve Cagdas, Ozgur Yigit, Ibrahim Hatemi","doi":"10.14744/SEMB.2025.78972","DOIUrl":"10.14744/SEMB.2025.78972","url":null,"abstract":"<p><p>We report the case of a 30-year-old female patient with Crohn's disease who was receiving infliximab and mesalazine therapy. She presented with left ear pain accompanied by bloody diarrhea and abdominal pain. Initial treatment with ciprofloxacin and aluminum acetate was ineffective, requiring hospitalization. She was treated with intravenous meropenem, clindamycin, and prednisolone, which led to symptom resolution after 12 days. However, 7 months later, the patient developed similar symptoms in the right ear without intestinal involvement. She was hospitalized and treated with intravenous antibiotics, followed by prednisolone treatment.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"275-278"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Phototherapy on Sleep, Fatigue and Quality of Life in Dermatology Patients: A Pilot Study.","authors":"Hazel Ezgi Kaya, Asli Aksu, Pinar Ozdemir Cetinkaya, Birgul Ozkesici Kurt, Ali Tanakol, Ilknur Kivanc Altunay","doi":"10.14744/SEMB.2026.90592","DOIUrl":"10.14744/SEMB.2026.90592","url":null,"abstract":"<p><strong>Objectives: </strong>Sleep disturbances and fatigue are prevalent among dermatology patients. Owing to the growing evidence on the effects of light-based therapies on neuropsychiatric disorders, this study aimed to investigate how narrow-band ultraviolet B (NB-UVB) phototherapy influences sleep quality and fatigue.</p><p><strong>Methods: </strong>In this prospective observational study, 30 patients receiving or scheduled to receive NB-UVB phototherapy were included. Phototherapy was administered 2-3 times per week with eye protection. Sleep quality, fatigue, and dermatology-specific quality of life were assessed using the Pittsburgh Sleep Quality Index (PSQI), Piper Fatigue Scale (PFS), and Dermatology Life Quality Index (DLQI), respectively. Measurements were performed at study entry and at the one-month follow-up.</p><p><strong>Results: </strong>The mean age was 48.2±12.9 years, and 63.3% of the patients were male. The most common diagnoses were vitiligo (40%), mycosis fungoides (26.7%), and psoriasis vulgaris (13.3%). The median PSQI score decreased from 8 at baseline to 5 at the one-month follow-up (p<0.001). The median PFS score decreased from 3.88 to 2.38 (p=0.019). DLQI showed no significant change. Changes in PSQI and PFS were significantly correlated (r=0.435, p=0.016). Multiple regression analysis identified ΔPFS, total cumulative dose, and ΔDLQI as independent predictors of ΔPSQI.</p><p><strong>Conclusion: </strong>NB-UVB phototherapy was associated with improvements in sleep quality and fatigue in dermatology patients over the course of treatment. These effects appear to be independent of changes in dermatology-specific quality of life and are likely mediated through neuroendocrine, circadian, and peripheral pathways. NB-UVB phototherapy may serve as an effective adjunctive treatment for sleep disturbances and fatigue in dermatology patients.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"263-270"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Body Mass Index with 28-Day Mortality in Adult Intensive Care Patients with Sepsis: A Retrospective Observational Study.","authors":"Olcay Dilken, Mustafa Altinay, Batuhan Bostan, Mehmet Nuri Yakar, Betul Duran, Feyzullah Orkut Duran, Sevde Sumeyye Iraz Soyalp, Merve Ipekoglu, Ziya Eren Cayir, Ayse Surhan Cinar","doi":"10.14744/SEMB.2026.03592","DOIUrl":"10.14744/SEMB.2026.03592","url":null,"abstract":"<p><strong>Objectives: </strong>The effect of obesity on sepsis outcomes remains controversial. Several studies have described an \"obesity paradox,\" whereby a higher body mass index (BMI) correlates with improved survival in critically ill patients. This study aimed to investigate the relationship between BMI and 28-day mortality in adult patients with sepsis admitted to the intensive care unit (ICU).</p><p><strong>Methods: </strong>We conducted a retrospective observational study including 83 adult patients diagnosed with sepsis according to the Sepsis-3 criteria who were admitted to the ICUs of Şişli Hamidiye Etfal Training and Research Hospital between June 2023 and June 2025. BMI was reported using World Health Organization categories and analyzed using three BMI groups based on the final cohort distribution. The primary endpoint was 28-day mortality. Multivariable logistic regression analysis was conducted with adjustment for age, sex, Sequential Organ Failure Assessment score, creatinine, and C-reactive protein.</p><p><strong>Results: </strong>The median age was 75 years (interquartile range, 66-82), and 55% of the patients were male. Survivors had a higher BMI than non-survivors (27.3 vs. 24.9 kg/m²; p=0.004) and higher albumin levels (p=0.024). BMI was inversely associated with 28-day mortality in the multivariable analysis (odds ratio, 0.74 per 1 kg/m²; 95% confidence interval, 0.58-0.91; p=0.008).</p><p><strong>Conclusion: </strong>Higher BMI was associated with lower 28-day mortality in septic ICU patients. Further prospective studies are needed to validate this relationship and explore the underlying potential mechanisms.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"172-179"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Utility of PTeye in Parathyroidectomy for Recurrent Hyperparathyroidism Due to Intramuscular Parathyroid Autograft Hyperplasia: A Case Report.","authors":"Mehmet Haciyanli, Selda Gucek Haciyanli, Hakan Kul, Farida Mustafayeva, Ceren Yavuz, Serkan Karaisli, Emine Ozlem Gur, Bulent Calik","doi":"10.14744/SEMB.2026.96572","DOIUrl":"10.14744/SEMB.2026.96572","url":null,"abstract":"<p><p>PTeye is a near-infrared autofluorescence device used intraoperatively to identify parathyroid tissue, typically using thyroid tissue as a reference. In patients with prior total thyroidectomy, the absence of thyroid tissue limits its standard application. Although the use of alternative reference tissues with the PTeye device in thyroidectomized patients has been reported, such data remain limited. Our case differs in that skeletal muscle was used specifically for the detection of recurrent intramuscular parathyroid tissue and may serve as a meaningful reference point for future clinical applications. A patient underwent total thyroidectomy for multinodular goiter and excision of a left lower parathyroid adenoma for primary hyperparathyroidism. The left upper gland was devascularized and autotransplanted into the left sternocleidomastoid muscle. Sixteen years later, recurrent primary hyperparathyroidism developed, and imaging revealed a lesion at the autograft site. During revision surgery, PTeye was used with skeletal muscle as the autofluorescence reference. PTeye accurately identified parathyroid tissue using skeletal muscle as the reference. Successful excision was confirmed by a significant intraoperative parathyroid hormone decline from 125 pg/mL to 35 pg/mL and postoperative histopathology consistent with hyperplasia. This case suggests that PTeye may be effectively used with skeletal muscle as a reference tissue in patients lacking thyroid tissue.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"288-292"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Psychometric Validity of the TikTok Addiction Scale Turkish Version: The Relationship between TikTok Addiction, Stress, and Personality.","authors":"Fikret Poyraz Cokmus, Sahsi Betul Didem Cayli, Orkun Aydin","doi":"10.14744/SEMB.2026.97355","DOIUrl":"10.14744/SEMB.2026.97355","url":null,"abstract":"<p><strong>Objectives: </strong>The rapid global proliferation of TikTok has increased the need for culturally adapted measurement tools to assess problematic TikTok use. This study aimed to evaluate the psychometric properties of the Turkish version of the TikTok Addiction Scale (TTAS-TR) and examine its associations with social media addiction, perceived stress, and personality traits.</p><p><strong>Methods: </strong>A cross-sectional online survey was administered to 508 Turkish TikTok users. Participants completed the TTAS-TR, the Bergen Social Media Addiction Scale (BSMAS), the Perceived Stress Scale (PSS-10), and the Big Five Personality Inventory (BFI-10). The factor structure of the scale was examined using confirmatory factor analysis. Internal consistency, test-retest reliability, concurrent validity, and incremental validity analyses were performed. Additionally, the predictive contribution of the TTAS-TR to perceived stress was evaluated using multivariate models beyond personality traits and social media use.</p><p><strong>Results: </strong>The findings supported the theorized six-factor structure of the TTAS-TR-salience, mood modification, tolerance, withdrawal, conflict, and relapse-demonstrating high internal consistency and stable test-retest reliability coefficients. TTAS-TR scores were positively associated with social media addiction and perceived stress. Findings regarding personality traits were consistent with established patterns in the literature: higher neuroticism and lower conscientiousness, openness to experience, and extraversion were associated with higher TTAS-TR scores. In multivariable models, the TTAS-TR made an additional contribution to explaining perceived stress beyond personality traits and social media use, with the tolerance subdimension showing a particularly strong association with stress.</p><p><strong>Conclusion: </strong>The TTAS-TR demonstrated strong factor validity, reliability, and concurrent and incremental validity in the Turkish sample. The scale appears to be a valid and reliable instrument for screening and research on problematic TikTok use. The tolerance dimension of TikTok use emerged as a prominent indicator associated with perceived stress.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"254-262"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Treatment of Pneumopericardium with Pericardiocentesis in a Premature Infant: A Case Report and Review of The Literature.","authors":"Esma Akboga, Adil Umut Zubarioglu, Irem Salk, Yusuf Iskender Coskun, Ebru Turkoglu Unal, Evrim Kiray Bas, Hasan Sinan Uslu, Ali Bulbul","doi":"10.14744/SEMB.2025.53900","DOIUrl":"10.14744/SEMB.2025.53900","url":null,"abstract":"<p><p>Neonatal pneumopericardium is a rare form of air leak syndrome associated with high morbidity and mortality. With advances in neonatal care, the incidence of pneumopericardium has decreased, as with other air leak syndromes; however, most cases occur in premature infants with a history of respiratory distress and mechanical ventilation. Pneumopericardium should be considered in the differential diagnosis of newborns experiencing sudden respiratory distress. Early diagnosis and appropriate treatment can significantly reduce mortality. This case report presents the management of isolated pneumopericardium using ultrasound-guided pericardiocentesis, which was detected after sudden clinical deterioration in a premature female infant born at 28 gestational weeks and followed up on mechanical ventilation. Recognition and prompt intervention by neonatal intensive care unit physicians significantly impact the patient's prognosis.</p>","PeriodicalId":42218,"journal":{"name":"Medical Bulletin of Sisli Etfal Hospital","volume":"60 2","pages":"283-287"},"PeriodicalIF":1.0,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148424923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}