Science Bulletin最新文献_第7页

From bioinks to living matter: bioprinting enters the "pure cell" era. 从生物墨水到生物物质：生物打印进入“纯细胞”时代。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 DOI: 10.1016/j.scib.2026.04.032

Yuan Huang, Qi Wang, Tanqing Long, Lu Han, Yen Wei, Juan Liu

引用次数: 0

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 DOI: 10.1016/j.scib.2026.04.030

Sen Gao, Jing Ren, Baoping Zhang, Lixian Yang, Yiqiang Wu, Yingying Zhang, Leitao Cao, Qing Li, Chunlei Zhang, Mingyue Miao, Haipeng Yu, Shouxin Liu, Jian Li, Shengjie Ling, Wenshuai Chen, Zuankai Wang

{"title":"Super retarding-flame wood.","authors":"Sen Gao, Jing Ren, Baoping Zhang, Lixian Yang, Yiqiang Wu, Yingying Zhang, Leitao Cao, Qing Li, Chunlei Zhang, Mingyue Miao, Haipeng Yu, Shouxin Liu, Jian Li, Shengjie Ling, Wenshuai Chen, Zuankai Wang","doi":"10.1016/j.scib.2026.04.030","DOIUrl":"https://doi.org/10.1016/j.scib.2026.04.030","url":null,"abstract":"<p><p>Wood, a sustainable and ubiquitous natural structural material, has been widely used in various fields. A bottleneck perplexing its applications is the inevitable flammability. Traditional anti-flammability methods, such as surface coating and internal decoration, still suffer from the possibility of wood combustion upon exposure to extreme flames, owing to the complexity imposed by the challenge to integrate the spatially localized flame retardants into the entire solid wood. Here, we develop a super retarding-flame wood, denoted as Surf-wood, that enables effective distribution of flame retardant metal salts in the hierarchical structures of wood cell walls through a facile molecular-scale cell wall engineering strategy. The Surf-wood exhibits a remarkable high limiting oxygen index of ∼100%, as well as 80% and 96% reduction in the peak of heat release rate and total smoke production compared with natural wood, suppresses combustion even when placed in harsh charcoal fire, and withstands 12 min-continuous burning at 1300 °C without structural collapse. This new material is scalable in production while maintaining the esthetics and other desirable properties of natural wood, which would open a new avenue for numerous functional applications.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":21.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remote sensing enables rapid assessment of the March 28, 2025 Myanmar earthquake 遥感技术能够对2025年3月28日缅甸地震进行快速评估。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2025-11-28 DOI: 10.1016/j.scib.2025.11.043

Nan Xu , Zihao Zhang , Qingquan Li , Yifu Ou , Wei Tu , Chao Yang , Chuanhua Zhu , Peng Gong , Hui Lu , Deliang Chen

引用次数: 0

Knocking out a bHLH transcription factor enhances crop drought tolerance 敲除bHLH转录因子可提高作物抗旱性。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2025-12-17 DOI: 10.1016/j.scib.2025.12.027

Jiazhuo Guo , Lijia Yang , Liang Xu , Liang Zhang , Huanyu Wang , Shule Ren , Jiaqi Zhang , Aipeng Li , Kaiyu Zhao , Ziqian Yan , Sheng Zhao , Xiaosong Ma , Shengxing Wang , Pengcheng Wei , Shiyong Song

引用次数: 0

Precise engineering and structural evolution of metallic silver nanoclusters 金属银纳米团簇的精密工程与结构演化。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2026-01-21 DOI: 10.1016/j.scib.2026.01.048

Lin Geng , Laurent Ruhlmann , Wei-Hui Fang

引用次数: 0

Dynamic hydrogen buffer integrated with single Pt sites for enhanced durability of high-temperature proton exchange membrane fuel cells 动态氢缓冲与单铂点集成，提高高温质子交换膜燃料电池的耐久性。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2026-02-26 DOI: 10.1016/j.scib.2026.02.041

Yabin Xu , Jing Tian , Li Wang , Jiuli Xia , Yandong Wu , Qie Liu , Jingjing Wang , Shiqian Du , Tingting Han , Miaoyu Li , Zuyao Jiang , Yaping Gu , Zhaoling Ma , Li Tao , Shuangyin Wang

{"title":"Dynamic hydrogen buffer integrated with single Pt sites for enhanced durability of high-temperature proton exchange membrane fuel cells","authors":"Yabin Xu , Jing Tian , Li Wang , Jiuli Xia , Yandong Wu , Qie Liu , Jingjing Wang , Shiqian Du , Tingting Han , Miaoyu Li , Zuyao Jiang , Yaping Gu , Zhaoling Ma , Li Tao , Shuangyin Wang","doi":"10.1016/j.scib.2026.02.041","DOIUrl":"10.1016/j.scib.2026.02.041","url":null,"abstract":"<div><div>The performance degradation caused by current reversal during start-up/shut-down (SU/SD) in proton exchange membrane fuel cells (PEMFCs), particularly severe in high-temperature PEMFCs (HT-PEMFCs), is conventionally mitigated by strategies that significantly increase system complexity and cost. In this work, the Co nanoparticles encapsulated by graphene layer supported Pt single atoms (Pt<sub>1</sub>/Co@N-C) catalyst is employed enhance the durability of membrane electrode assemblies (MEA) under SU/SD situations. The Pt<sub>1</sub>/Co@N-C catalyst with ultralow Pt loading exhibits a comparable hydrogen oxidation reaction (HOR) activity compared to the Pt/C catalyst, and a suppression of oxygen reduction reaction (ORR) activity. Notably, the encapsulated Co nanoparticles with an fcc crystal structure act as the hydrogen buffer, the storage/escape of H<sub>2</sub> in the lattice interstices of Co metal can effectively resist current reversal of the MEA. The Pt<sub>1</sub>/Co@N-C with ultralow Pt loading (35 μg<sub>Pt</sub> cm<sup>−2</sup>) displays an outstanding performance in the HT-PEMFCs, achieving a peak power density of 555 mW cm<sup>−2</sup> and a stability of 54 μV h<sup>−1</sup>. The catalyst demonstrates a markedly enhanced durability compared to the Pt/C catalyst during SU/SD, and improves the resist current reversal time to 50 min (Pt/C, 2 min) under fuel starvation condition. This work presents innovative strategies for developing anode catalyst with low Pt loading and superior durability in HT-PEMFCs.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 7","pages":"Pages 1714-1722"},"PeriodicalIF":21.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Planar assembly of dual single-atom engineered mesoporous carbon onto Ti3C2Tx for high-energy lithium-ion batteries 高能锂离子电池用双单原子工程介孔碳在Ti3C2Tx上的平面组装。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2026-02-26 DOI: 10.1016/j.scib.2026.02.040

Haitao Li , Cheng Tang , Siyuan Huang , Aijun Du , Minghong Wu , Haijiao Zhang

{"title":"Planar assembly of dual single-atom engineered mesoporous carbon onto Ti3C2Tx for high-energy lithium-ion batteries","authors":"Haitao Li , Cheng Tang , Siyuan Huang , Aijun Du , Minghong Wu , Haijiao Zhang","doi":"10.1016/j.scib.2026.02.040","DOIUrl":"10.1016/j.scib.2026.02.040","url":null,"abstract":"<div><div>Two-dimensional mesoporous carbon materials possessing dual structural advantages have shown great application potential in energy storage kingdom. However, the bottlenecks, such as low capacity and few active centers, have become their main obstacles for the large-scale applications. Herein, a facile planar assembly strategy has been developed to integrate heteroatoms-functionalized mesoporous carbon with bimodal pores onto Ti<sub>3</sub>C<sub>2</sub>T<em><sub>x</sub></em>. Experimental results indicate that phytic acid serves as a multifunctional regulator during the assembly process. Its strong coordination ability with metal ions ensures the successful introduction of Fe/Co single atoms, while abundant hydroxyl groups enhance the robust anchoring effect of micelles onto Ti<sub>3</sub>C<sub>2</sub>T<em><sub>x</sub></em> at the molecular level and facilitate the coexistence of spherical and cylindrical pores. Synchronous radiation and theoretical calculations verify that the highly dispersed metal single atoms with the Fe<img>N<sub>4</sub>/Co<img>N<sub>4</sub> configurations, coupled with a high nitrogen doping, significantly enhance the lithium-ion adsorption and storage sites. <em>In-situ</em>/<em>ex-situ</em> characterizations reveal that the bimodal mesopores effectively accelerate ion transport kinetics. The designed electrode exhibits an ultra-high lithium storage capability of 713.2 mA h g<sup>−1</sup> at 0.1 A g<sup>−1</sup> after 100 cycles. This work provides a promising universal strategy for developing other metal single atoms-doped mesoporous carbon electrode materials with high lithium storage capability.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 7","pages":"Pages 1734-1745"},"PeriodicalIF":21.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strongly spatial-confined self-assembled monolayers for high-performance perovskite photovoltaics 用于高性能钙钛矿光伏的强空间约束自组装单层。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2026-02-27 DOI: 10.1016/j.scib.2026.02.050

Dongyang Li , Qiming Yin , Zhiwei Ren , Guihua Zhang , Jie Li , Qianyi Li , Yu Han , Sibo Li , Lihan Pang , Hao Xia , Guang Yang , Longbin Qiu , Ruijie Ma , Baomin Xu , Gang Li , Chun Cheng

{"title":"Strongly spatial-confined self-assembled monolayers for high-performance perovskite photovoltaics","authors":"Dongyang Li , Qiming Yin , Zhiwei Ren , Guihua Zhang , Jie Li , Qianyi Li , Yu Han , Sibo Li , Lihan Pang , Hao Xia , Guang Yang , Longbin Qiu , Ruijie Ma , Baomin Xu , Gang Li , Chun Cheng","doi":"10.1016/j.scib.2026.02.050","DOIUrl":"10.1016/j.scib.2026.02.050","url":null,"abstract":"<div><div>Self-assembled monolayers (SAMs) as hole-selective contacts have driven the power conversion efficiencies (PCEs) of inverted perovskite solar cells (IPSCs) beyond 27%, yet their poor operational stability remains a major barrier to commercialization. We report that strengthening the spatial confinement of SAMs through robust out-of-plane anchoring and dense in-plane packing can effectively suppress molecular desorption and enhance thermal and solvent resistance. A custom-designed molecule, MeO-PABDCB, forms strong bonds with both the underlying indium tin oxide (ITO) and the overlying perovskite, while its rigid, planar backbone promotes tight π-π stacking (3.72 Å). This multi-dimensionally confined SAM structure not only resists solvent washing and thermal degradation but also mitigates interfacial strain in the perovskite layer, facilitating highly efficient and stable hole extraction. The resulting IPSCs achieve a champion PCE of 26.54% with a fill factor of 86.4% and retain 90% of their initial efficiency after 1000 h of maximum power point tracking (ISOS-L-1). Devices also withstand 250 harsh thermal cycles between −40 and 85 °C (IEC61215 and ISOS-T-3) while preserving over 90% of their initial performance. This work establishes spatial confinement as a general molecular design principle toward durable and high-performance perovskite optoelectronics.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 7","pages":"Pages 1677-1685"},"PeriodicalIF":21.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147455184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Targeting focal adhesion kinase: from molecular mechanisms to next-generation cancer therapeutics 靶向黏附激酶：从分子机制到下一代癌症治疗。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2026-02-27 DOI: 10.1016/j.scib.2026.02.048

Jie Chen , Zixuan Bu , Qimin Zhan

{"title":"Targeting focal adhesion kinase: from molecular mechanisms to next-generation cancer therapeutics","authors":"Jie Chen , Zixuan Bu , Qimin Zhan","doi":"10.1016/j.scib.2026.02.048","DOIUrl":"10.1016/j.scib.2026.02.048","url":null,"abstract":"<div><div>Focal adhesion kinase (FAK) is a key cytoplasmic tyrosine kinase that transmits signals from integrins and growth factors to control cell migration, metastasis, growth and survival. FAK can modulate prominent oncogenic pathways, such as the phosphatidylinositol 3 kinase/protein kinase B (PI3K/AKT) and Rat Sarcoma virus/extracellular signal-regulated kinase (Ras/ERK) pathway, through autophosphorylation at Y397 and subsequent conformational activation. Notably, FAK is overexpressed and activated in many solid tumors. Its expression levels are correlated with tumor stage, lymph node metastasis, and poor prognosis. Moreover, FAK promotes tumor malignancy by inducing epithelial-mesenchymal transition (EMT), chemoresistance, and stemness properties. However, targeting FAK is considerably challenging owing to signal complexity. To date, only eight small-molecule FAK inhibitors have reached the clinical trial stage, mainly in combination with chemotherapy, targeted therapy, or immunotherapy. Recent advances, such as proteolysis-targeting chimeras (PROTACs) degraders, protein-protein interaction (PPI) blockers, allosteric inhibitors, and natural products, offer promising opportunities to overcome current therapeutic challenges. The present review provides a comprehensive discussion of FAK, ranging from its structure and regulatory mechanisms to its central role in tumor malignancy and the current status of inhibitor development, aiming to inform future translational efforts in solid tumors.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 7","pages":"Pages 1812-1830"},"PeriodicalIF":21.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147442279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extreme climate-driven quartz dissolution alters global river-ocean silicon and carbon cycles 极端气候驱动的石英溶解改变了全球河流-海洋硅和碳循环。

IF 21.1 1区综合性期刊

Science Bulletin Pub Date : 2026-04-15 Epub Date: 2025-12-08 DOI: 10.1016/j.scib.2025.12.006

Zimin Li , Yunqiang Wang , Yong Hu , Peng Shi , Kai Yue , Zhaoliang Song

引用次数: 0