Science Bulletin最新文献_第4页

Electric-field-responsive solvation: stabilizing high-voltage lithium metal batteries through adaptive interfacial chemistry. 电场响应溶剂化：通过自适应界面化学稳定高压锂金属电池。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-10-12 DOI: 10.1016/j.scib.2026.10.015

Zhu Cheng, Marnix Wagemaker

引用次数: 0

Associations of body shape, visceral adiposity, and metabolic function indices with risk of major noncommunicable diseases: evidence from a nationwide population cohort. 体型、内脏脂肪和代谢功能指数与主要非传染性疾病风险的关联：来自全国人口队列的证据

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-10-11 DOI: 10.1016/j.scib.2026.10.007

Yi Wu, Limei Nie, Yue Cai, Chunying Lin, Yuan Shen, Zitong Wang, Xiaoyan Zhang, Bowang Chen, Yang Yang, Jianlan Cui, Wei Xu, Lijuan Song, Hao Yang, Wenyan He, Yan Zhang, He Xiao, Xi Li, Wei Zhao

{"title":"Associations of body shape, visceral adiposity, and metabolic function indices with risk of major noncommunicable diseases: evidence from a nationwide population cohort.","authors":"Yi Wu, Limei Nie, Yue Cai, Chunying Lin, Yuan Shen, Zitong Wang, Xiaoyan Zhang, Bowang Chen, Yang Yang, Jianlan Cui, Wei Xu, Lijuan Song, Hao Yang, Wenyan He, Yan Zhang, He Xiao, Xi Li, Wei Zhao","doi":"10.1016/j.scib.2026.10.007","DOIUrl":"https://doi.org/10.1016/j.scib.2026.10.007","url":null,"abstract":"<p><p>Comparative data evaluating the predictive performance of various obesity and metabolic indices for multiple noncommunicable diseases (NCDs) remain limited. We used the data sourced from the Health Evaluation and risk Reduction through nationwide Teamwork cohort (ChinaHEART), a national population-based study that enrolled 4,258,033 Chinese adults and followed them for more than 20 million person-years between November 2014 and December 2023. Fifteen obesity and metabolic indices were categorized into three groups: (1) body shape-related indices, including body mass index (BMI), body roundness index (BRI), waist-to-height ratio (WHtR), a body shape index (ABSI), weight-adjusted waist index (WWI), and conicity index (CI); (2) visceral fat-related indices, including lipid accumulation product (LAP) and Chinese visceral adiposity index (CVAI); and (3) metabolic function-related indices, including triglyceride-glucose index (TyG), TyG-BMI, TyG-BRI, TyG-WHtR, TyG-ABSI, TyG-WWI, and TyG-CI. The study outcomes comprised composite events of death or first hospitalization attributable to each of cardiovascular diseases (CVD), diabetes mellitus (DM), cancers, and chronic obstructive pulmonary disease (COPD) individually. Composite obesity and metabolic indices reflecting visceral adiposity accumulation and insulin resistance, respectively exhibited enhanced predictive accuracy for cardiovascular and diabetic risk, whereas their performance for cancer and COPD was comparatively limited. These findings support the paradigm that weight management strategies should be guided by risk assessments rather than relying solely on body weight or body shape. Furthermore, the development of diverse definitions for obesity measurement and management tailored to different population subgroups is warranted.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":20.7,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-effect confinement engineering reconciles electromagnetic wave absorption with marine corrosion protection. 双效约束工程将电磁波吸收与海洋防腐结合起来。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-10-05 DOI: 10.1016/j.scib.2026.10.013

Xi Li, Yongxin Qian, Daguang Li, Xiao Liu, Gengping Wan, Xuefei Xu, Lei Yu, Lihong Wu, Jie Kong, Guizhen Wang

{"title":"Dual-effect confinement engineering reconciles electromagnetic wave absorption with marine corrosion protection.","authors":"Xi Li, Yongxin Qian, Daguang Li, Xiao Liu, Gengping Wan, Xuefei Xu, Lei Yu, Lihong Wu, Jie Kong, Guizhen Wang","doi":"10.1016/j.scib.2026.10.013","DOIUrl":"https://doi.org/10.1016/j.scib.2026.10.013","url":null,"abstract":"<p><p>The simultaneous achievement of efficient electromagnetic wave absorption (EWA) and long-term corrosion protection in complex marine environments remains challenging due to inherent structural conflicts between porous electromagnetic absorbers and compact anticorrosion coatings. Herein, a multi-scale spatial assembly strategy is proposed to construct a three-dimensional hollow spherical carbon foam (HSCF) decorated with layered double hydroxide (LDH) nanosheets via a three-stage process (protonation, morphological reconstruction, and confined assembly) to realize a dual-effect confinement mechanism. From the perspective of electromagnetic energy confinement, enhanced synergistic effects among the architectural units induce intensive scattering and polarization loss, achieving a minimum reflection loss of -68.11 dB and a maximum effective absorption bandwidth of 7.40 GHz. Electromagnetic simulations further confirm the outstanding radar stealth capabilities across a wide range of incident angles. From the perspective of corrosive media confinement, the tortuous HSCF skeleton physically retards the diffusion of corrosive species, while the anchored LDH nanosheets actively capture chloride ions via anion exchange. Consequently, the resulting HSCF@LDH/epoxy (EP) composite coating exhibits excellent corrosion resistance, featuring a significantly enhanced corrosion potential and reduced current density compared with the pure EP coating. Overall, this dual-effect confinement mechanism enabled by the multi-scale spatial assembly strategy establishes a new structural paradigm for the next generation of multifunctional EWA materials for extreme operational environments.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":20.7,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149190570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanistic state-space mapping of degradation in perovskite solar cells. 钙钛矿太阳能电池降解的机械状态空间映射。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-10-03 DOI: 10.1016/j.scib.2026.10.010

D Kishore Kumar, Manuel J Mendes

引用次数: 0

A lncCtxnd1-encoded micropeptide suppresses hepatocellular carcinoma by reprogramming tumor-associated macrophages. lncctxnd1编码的微肽通过重编程肿瘤相关巨噬细胞抑制肝细胞癌。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-10-03 DOI: 10.1016/j.scib.2026.10.009

Ziyang Liu, Yanan Gao, Yiming Zhang, Zewen Su, Hao Wang, Xuetao Huang, Dongdong Zhang, Haiyan Yue, Junjie He, Haidong Li, Yuqing Liu, Mengtong Xu, Zijian Zhang, Jingfeng Qian, Xiaomin Chen, Babak Razani, Jianzhong Jeff Xi, Jianjun Luo, Pengyuan Yang, Runsheng Chen

引用次数: 0

Plant histone variants: deposition mechanisms, functional diversification, and translational prospects. 植物组蛋白变异：沉积机制、功能多样化和翻译前景。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-10-03 DOI: 10.1016/j.scib.2026.10.012

Bowen Li, Yahui Zhao, Lefei Gao, Chengcai Chu, Shengbo He

{"title":"Plant histone variants: deposition mechanisms, functional diversification, and translational prospects.","authors":"Bowen Li, Yahui Zhao, Lefei Gao, Chengcai Chu, Shengbo He","doi":"10.1016/j.scib.2026.10.012","DOIUrl":"https://doi.org/10.1016/j.scib.2026.10.012","url":null,"abstract":"<p><p>Histone variants are non-allelic isoforms of canonical histones that assemble into nucleosomes via replication-independent pathways, reshaping chromatin biophysical properties and transcriptional control at specific genomic loci. Constrained by their sessile lifestyle, plants have evolved a rich set of histone variants, including lineage-specific innovations such as heterochromatin-stabilizing H2A.W, stress-inducible H1.3, gametophyte-restricted H2B.8, Arabidopsis H3.14, and Oryza-specific H4.V. This review systematically summarizes recent advances in plant histone variants from three dimensions: (1) histone chaperones and remodelers governing variant genomic targeting; (2) variant functions across plant developmental and stress responses; (3) evolutionary origins and epigenetic crosstalk underlying variant diversification. Comparative and pan-genomic analyses reveal that lineage-specific gene-family expansion and intraspecific structural variation jointly shape plant histone variant repertoires. Natural histone variant haplotypes provide untapped genetic resources for fine-tuning chromatin responsiveness, though their causal links to chromatin states and agronomic traits remain to be experimentally validated. We propose the concept of pangenomic chromatin alleles, in which naturally occurring histone-variant haplotypes, copy-number variations, and structural configurations at histone-variant loci may be leveraged to fine-tune chromatin responsiveness and inform future pan-genome-based chromatin haplotype breeding. We further discuss how crop pangenomes, multi-modal artificial intelligence, and precision epigenome editing can accelerate variant discovery, occupancy prediction, and functional prioritization, while emphasizing the necessity of rigorous genetic and biochemical validation for all predictive findings.</p>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":" ","pages":""},"PeriodicalIF":20.7,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unknotting as actuation: topologically programmed leaping and flight in insect-scale soft actuators 作为驱动的解结：昆虫级软驱动器的拓扑编程跳跃和飞行。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-09-30 Epub Date: 2026-08-16 DOI: 10.1016/j.scib.2026.07.082

Jing Bian, Fan Zhang, Junwen Zhong, YongAn Huang

引用次数: 0

Minutes-long soft X-ray prompt emission from a compact object merger 从一个紧凑的物体合并发出的几分钟长的软x射线。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-09-30 Epub Date: 2026-08-10 DOI: 10.1016/j.scib.2026.08.021

An Li, Chen-Wei Wang, Niccolò Passaleva, Jie An, Bin-Bin Zhang, Eleonora Troja, Yi-Han Iris Yin, Yuan Liu, Shao-Lin Xiong, Li-Ping Xin, Yi-Xuan Shao, Jun Yang, Hui Sun, Dong Xu, Yu-Han Yang, Roberto Ricci, He Gao, Sarah Antier, Rosa L. Becerra, Jia-Xin Cao, Bing Zhang

{"title":"Minutes-long soft X-ray prompt emission from a compact object merger","authors":"An Li, Chen-Wei Wang, Niccolò Passaleva, Jie An, Bin-Bin Zhang, Eleonora Troja, Yi-Han Iris Yin, Yuan Liu, Shao-Lin Xiong, Li-Ping Xin, Yi-Xuan Shao, Jun Yang, Hui Sun, Dong Xu, Yu-Han Yang, Roberto Ricci, He Gao, Sarah Antier, Rosa L. Becerra, Jia-Xin Cao, Bing Zhang","doi":"10.1016/j.scib.2026.08.021","DOIUrl":"10.1016/j.scib.2026.08.021","url":null,"abstract":"<div><div>Compact object mergers are multi-messenger sources and known progenitors of some gamma-ray bursts, bright flashes of high-energy radiation powered by a central engine, either an accreting black hole or a neutron star. Our understanding of these events has so far been shaped primarily by observations in the gamma-ray band, leaving their prompt phase poorly constrained at lower energies. A long-lasting (<span><math><mrow><mo>≈</mo></mrow></math></span>100 s) engine-driven X-ray emission was discussed to explain rapidly fading X-ray afterglows following several (<span><math><mrow><mo>≈</mo></mrow></math></span>30%) bursts of short (<span><math><mrow><mi>≲</mi></mrow></math></span>2 s) duration. However, this prompt X-ray component was not directly observed and past candidates were not confirmed. Here we report the discovery of EP250704a containing a minutes-long (<span><math><mrow><mo>∼</mo></mrow></math></span>560 s) flash of soft (0.5–4 keV) X-rays immediately following the short (<span><math><mrow><mo>∼</mo></mrow></math></span>0.4 s) GRB 250704B. The variability and spectral shape of this emission are inconsistent with the canonical picture of a hard, accretion-powered spike followed by a standard external-shock afterglow. Instead, the long-soft bump points to a distinct phase of prompt emission in X-rays, which would not have been detected without the soft X-ray coverage of Einstein Probe. The detection of a prompt soft X-ray counterpart in an otherwise ordinary short GRB shows that long-lasting X-ray emission is likely a common feature of merger-driven bursts and a promising electromagnetic counterpart to gravitational wave sources.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 18","pages":"Pages 4657-4664"},"PeriodicalIF":20.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148786765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A star’s death by a thousand cuts: the runaway periodic eruptions of AT2023uqm 一颗恒星千刀万刀的死亡：AT2023uqm失控的周期性喷发。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-09-30 Epub Date: 2026-08-19 DOI: 10.1016/j.scib.2026.08.025

Yibo Wang, Tinggui Wang, Shifeng Huang, Jiazheng Zhu, Ning Jiang, Wenbin Lu, Rongfeng Shen, Shiyan Zhong, Dong Lai, Yi Yang, Xinwen Shu, Tianyu Xia, Di Luo, Jianwei Lyu, Alexei V. Filippenko, Thomas G. Brink, Weikang Zheng, Minxuan Cai, Zelin Xu, Mingxin Wu, Yingxi Zuo

{"title":"A star’s death by a thousand cuts: the runaway periodic eruptions of AT2023uqm","authors":"Yibo Wang, Tinggui Wang, Shifeng Huang, Jiazheng Zhu, Ning Jiang, Wenbin Lu, Rongfeng Shen, Shiyan Zhong, Dong Lai, Yi Yang, Xinwen Shu, Tianyu Xia, Di Luo, Jianwei Lyu, Alexei V. Filippenko, Thomas G. Brink, Weikang Zheng, Minxuan Cai, Zelin Xu, Mingxin Wu, Yingxi Zuo","doi":"10.1016/j.scib.2026.08.025","DOIUrl":"10.1016/j.scib.2026.08.025","url":null,"abstract":"<div><div>Stars on bound orbits around a supermassive black hole may undergo repeating partial tidal disruption events (rpTDEs), producing periodic flares. While several candidates have been suggested, definitive confirmation of these events remains elusive. We report the discovery of AT2023uqm, a nuclear transient that has exhibited at least five periodic optical flares, making it only the second confirmed case of periodicity after ASASSN-14ko. Uniquely, the flares from AT2023uqm show a nearly exponential increase in energy—a “runaway” phenomenon signaling the star’s progressive destruction. This behavior is consistent with rpTDEs of low-mass main-sequence stars or evolved giant stars. Multiwavelength observations and spectroscopic analysis of the two most recent flares reinforce its interpretation as an rpTDE. Intriguingly, each flare displays a similar double-peaked structure, potentially originating from a double-peaked mass fallback rate or two discrete collisions per orbit. The extreme ratio of peak separation to orbital period draws attention to the possibility of a giant star being disrupted, which could be distinguished from a low-mass main-sequence star by its future mass-loss evolution. Our analysis demonstrates the power of rpTDEs to probe the properties of disrupted stars and the physical processes of tidal disruption, though it is currently limited by our knowledge of these events. AT2023uqm emerges as the most compelling rpTDE thus far, serving as a crucial framework for modeling and understanding these phenomena.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 18","pages":"Pages 4645-4656"},"PeriodicalIF":20.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148878785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neddylation E2 enzyme UBE2M inhibits inflammatory lung tumor microenvironment by blocking the cGAS-STING signal upon KrasG12D activation 类泛素化E2酶UBE2M通过阻断KrasG12D激活时的cGAS-STING信号抑制炎性肺肿瘤微环境。

IF 20.7 1区综合性期刊

Science Bulletin Pub Date : 2026-09-30 Epub Date: 2026-08-24 DOI: 10.1016/j.scib.2026.08.050

Yawen Zheng, Cantong Chen, Xufan Li, Zhouyang Li, Hua Li, Mingjia Tan, Danyi Zhai, Fengwu Zhang, Wenjing Lu, Zhihua Chen, Yongchao Zhao, Pengyuan Liu, Yan Lu, Xiufang Xiong, Yi Sun

{"title":"Neddylation E2 enzyme UBE2M inhibits inflammatory lung tumor microenvironment by blocking the cGAS-STING signal upon KrasG12D activation","authors":"Yawen Zheng, Cantong Chen, Xufan Li, Zhouyang Li, Hua Li, Mingjia Tan, Danyi Zhai, Fengwu Zhang, Wenjing Lu, Zhihua Chen, Yongchao Zhao, Pengyuan Liu, Yan Lu, Xiufang Xiong, Yi Sun","doi":"10.1016/j.scib.2026.08.050","DOIUrl":"10.1016/j.scib.2026.08.050","url":null,"abstract":"<div><div>UBE2M, also known as UBC12, is one of two neddylation conjugation enzymes. The <em>in vitro</em> cell culture work showed that UBE2M is essential for the growth and survival of cancer cells, but its <em>in vivo</em> role in tumorigenesis, particularly in the tumor microenvironment (TME), remains elusive. Here, we report that in a well-established <em>Kras<sup>G12D</sup></em> lung tumor mouse model, <em>Ube2m</em> deletion caused an inflammatory TME, severe lung edema, and early death. Mechanistically, while <em>Kras</em><sup><em>G12D</em></sup> activates MAPK and mTORC1 signals for proliferation, <em>Ube2m</em> deletion increases mitochondrial MOMP/mPTP and inhibits Parkin neddylation and activity, leading to compromised mitophagy. The combination of <em>Kras<sup>G12D</sup></em> activation and <em>Ube2m</em> deletion caused cytoplasmic release of damaged mitochondrial DNA to activate the cGAS-STING-NF-κB pathway, followed by inflammatory cytokine secretion, immune cell infiltration, and inflammatory TME. This process is largely blocked by the STING antagonist H-151, indicating a causal role of the cGAS-STING axis. In human lung cancer with <em>KRAS</em> mutations, low UBE2M expression is correlated with high infiltrations of immune cells, demonstrating its relevance to human disease. Our study unexpectedly showed a paracrine role of Ube2m in the prevention of TME upon <em>Kras<sup>G12D</sup></em> activation in the lung.</div></div>","PeriodicalId":421,"journal":{"name":"Science Bulletin","volume":"71 18","pages":"Pages 4742-4761"},"PeriodicalIF":20.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0