PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference最新文献

{"title":"A modified Langendorff-free method for isolation of cardiomyocytes from adult rat heart","authors":"T. Myachina, X. Butova, A. D. Khohlova","doi":"10.1063/1.5134291","DOIUrl":"https://doi.org/10.1063/1.5134291","url":null,"abstract":"Single isolated cardiomyocytes that are free from connective tissue and endothelium are widely used to investigate cellular and molecular mechanisms of cardiac regulation in the healthy hart and pathology. In this study, we present a new method to obtain single myocytes from adult rat hearts for biophysical experiments. We compare cell morphometry and parameters of intercellular calcium transient and contraction of rat ventricular cells isolated by Langendorff-free injection method and traditional Langendirff-based perfusion technique. Using the injection protocol, we found the number of viable cardiac myocytes with good morphometric characteristic was higher compared with the Langendorff-protocol. In both protocols, the cells retained rod-shape and sarcomere striation. The absence of statistically significant differences in the morphometric characteristics, calcium handling and mechanical activity of cardiomyocytes isolated by two different methods indicated that a new injection method is a simple adequate alternative for cardiomyocyte isolation to the Langendorff-based perfusion technique.Single isolated cardiomyocytes that are free from connective tissue and endothelium are widely used to investigate cellular and molecular mechanisms of cardiac regulation in the healthy hart and pathology. In this study, we present a new method to obtain single myocytes from adult rat hearts for biophysical experiments. We compare cell morphometry and parameters of intercellular calcium transient and contraction of rat ventricular cells isolated by Langendorff-free injection method and traditional Langendirff-based perfusion technique. Using the injection protocol, we found the number of viable cardiac myocytes with good morphometric characteristic was higher compared with the Langendorff-protocol. In both protocols, the cells retained rod-shape and sarcomere striation. The absence of statistically significant differences in the morphometric characteristics, calcium handling and mechanical activity of cardiomyocytes isolated by two different methods indicated that a new injection method is a simple adequa...","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117330255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Template synthesis of ZnSe2O5 nanocrystals","authors":"A. Akylbekova, A. Dauletbekova, Z. Baymukhanov, A. Kozlovsky, A. Usseinov","doi":"10.1063/1.5134152","DOIUrl":"https://doi.org/10.1063/1.5134152","url":null,"abstract":"The results on the formation of zinc diselenide nanocrystals by the method of electrochemical deposition on the track template a-SiO2/Si-n are presented. Track template a-SiO2/Si-n was obtained by irradiation with ions xenon with an energy of 200 MeV, with fluences of 107–108 ions/cm2. X-ray diffraction analysis showed that ZnSe2O5 nanocrystals have an orthorhombic crystal structure, the space group is Pbcn (60). The average unit cell parameters were: a = 6.80307 A; b = 10.35266 A; c = 6.14842 A.The results on the formation of zinc diselenide nanocrystals by the method of electrochemical deposition on the track template a-SiO2/Si-n are presented. Track template a-SiO2/Si-n was obtained by irradiation with ions xenon with an energy of 200 MeV, with fluences of 107–108 ions/cm2. X-ray diffraction analysis showed that ZnSe2O5 nanocrystals have an orthorhombic crystal structure, the space group is Pbcn (60). The average unit cell parameters were: a = 6.80307 A; b = 10.35266 A; c = 6.14842 A.","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115683406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conduction mechanisms in memristors based on nanotubular arrays of zirconium oxide","authors":"I. Petrenyov, A. Vokhmintsev, R. Kamalov, I. Weinstein","doi":"10.1063/1.5134393","DOIUrl":"https://doi.org/10.1063/1.5134393","url":null,"abstract":"","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"220 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131456153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial magnetic flux distribution in an object magnetized by three-pole electromagnet locally","authors":"V. Kostin, O. Vasilenko, A. Byzov, A. V. Petukhova","doi":"10.1063/1.5134305","DOIUrl":"https://doi.org/10.1063/1.5134305","url":null,"abstract":"","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131670296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiopharmaceutical dose distribution in different organs and tissues for Lu-177 with different carrier","authors":"Hesham MH Zakaly, M. Mostafa, M. Zhukovsky","doi":"10.1063/1.5134421","DOIUrl":"https://doi.org/10.1063/1.5134421","url":null,"abstract":"177Lu refers to rare earth elements from a group of lanthanides. Relative to its short time span, 177Lu has virtually pervaded all areas of in vivo radionuclide therapy and becomes one of important keys for therapeutic radionuclides of choice for targeted radionuclide therapy. The rising interest in the use of 177Lu in targeted molecular therapies has primarily developed from recent unmatched advances in molecular and cell biology, which include the use of peptides targeted to cell surface receptors, which are overexpressed on the surface of tumour cells. Therefore, the use of 177Lu-labelled radiopharmaceuticals have been the major factors evoking excitement among researchers and capturing the imagination of the clinical community thanks to advances in molecular and cellular biology. In this work, radiopharmaceutical comparison for 177Lu absorbed dose in health human organs and tissues is presented. The comparison between unlabelled 177Lu (ionic form) and labelled with 177Lu-MDP (methylenediphosphonate) a...","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127159754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rigorous derivation of Pareto principle from the Central Limit Theorem","authors":"I. Kashin","doi":"10.1063/1.5134262","DOIUrl":"https://doi.org/10.1063/1.5134262","url":null,"abstract":"","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126852245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the dynamics of dissolution of pharmaceuticals in water by calorimetric method","authors":"A. Kharlamova, G. Koposov","doi":"10.1063/1.5134181","DOIUrl":"https://doi.org/10.1063/1.5134181","url":null,"abstract":"A study of dissolution of drugs was performed using the Peltier elements. The dependences for different types of substances were obtained. This study determined two parameters for the physical studies of water-soluble pharmacological drugs.","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125343085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing of a supporting program for operator of research nuclear reactor","authors":"N. A. Vasyutin, V. Litovchenko, O. L. Tashlykov","doi":"10.1063/1.5134336","DOIUrl":"https://doi.org/10.1063/1.5134336","url":null,"abstract":"The features of design and current information support of operation of research nuclear reactor IVV-2M are described. Data on design code of the ICC intended for calculation of energy release in separate cells of reactor are given. Features of the code, causing the need for long manual preparation and input of the original data and excluding the calculation of energy release in real time. The article describes the program’s algorithm development that support the operator of the research nuclear reactor IVV-2M which able to solve this problem. The program envisages the simplification of input data for calculation, and automatic collection of data for the calculation by changing the position of the governing bodies of the reactor.The features of design and current information support of operation of research nuclear reactor IVV-2M are described. Data on design code of the ICC intended for calculation of energy release in separate cells of reactor are given. Features of the code, causing the need for long manual preparation and input of the original data and excluding the calculation of energy release in real time. The article describes the program’s algorithm development that support the operator of the research nuclear reactor IVV-2M which able to solve this problem. The program envisages the simplification of input data for calculation, and automatic collection of data for the calculation by changing the position of the governing bodies of the reactor.","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116905520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimate the absolute efficiency by MATLAB for the NaI (Tl) detector using IAEA-314","authors":"Hesham MH Zakaly, M. Uosif, S. Issa, Mujahed A. Saif, M. Tammam, A. El-Taher","doi":"10.1063/1.5134399","DOIUrl":"https://doi.org/10.1063/1.5134399","url":null,"abstract":"This works amid to calculating the absolute efficiency at any interesting γ–energy in the energy range between 10 and 1764 keV. by using fit function which has been developed to calculate theoretically the absolute γ-ray detection efficiencies of a cylindrical NaI(Tl) crystal. Efficiency of the NaI(Tl) calculator is a program built in MATLAB by the author of this paper to make it easier to calculate the efficiency of standard source. The absolute γ -ray detection efficiencies have been calculated for detectors 3˝ x 3˝ inches NaI(Tl) crystal. The absolute efficiency of the NaI (Tl) detector was calculated using standard sources (IAEA-314) which have known activity of 226Ra (732 Bqkg-1) and 232Th (17.8 ppm). In this calculation, experimental and theoretical efficiencies have been calculated. The uncertainties of efficiency calibration have been calculated also for quality control. Measurements were performed with calibrated point source. Gamma-ray energies under consideration were 0.356, 0.662, 1.17 and 1.33 MeV. Efficiency function was obtained by applying Weibull Model equation to the experimental efficiency data which give Best agreement between experimental and theoretical absolute detection efficiencies of 3×3-inch detector for gamma energy.This works amid to calculating the absolute efficiency at any interesting γ–energy in the energy range between 10 and 1764 keV. by using fit function which has been developed to calculate theoretically the absolute γ-ray detection efficiencies of a cylindrical NaI(Tl) crystal. Efficiency of the NaI(Tl) calculator is a program built in MATLAB by the author of this paper to make it easier to calculate the efficiency of standard source. The absolute γ -ray detection efficiencies have been calculated for detectors 3˝ x 3˝ inches NaI(Tl) crystal. The absolute efficiency of the NaI (Tl) detector was calculated using standard sources (IAEA-314) which have known activity of 226Ra (732 Bqkg-1) and 232Th (17.8 ppm). In this calculation, experimental and theoretical efficiencies have been calculated. The uncertainties of efficiency calibration have been calculated also for quality control. Measurements were performed with calibrated point source. Gamma-ray energies under consideration were 0.356, 0.662, 1.17 and 1.3...","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"357 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116054583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of nanopowders and nearly transparent Y2O3 ceramics from Y2(OH)5NO3•nH2O precursors","authors":"D. Aleshin, S. V. Buynachev, M. Mashkovtsev, E. Gordeev","doi":"10.1063/1.5134153","DOIUrl":"https://doi.org/10.1063/1.5134153","url":null,"abstract":"Synthesis of nanopowders and nearly transparent Y2O3 ceramics from yttrium hydroxynitrate (Y2(OH)5NO3•nH2O) precursors precipitated at constant pH from 7 to 10 was investigated. It is shown that the pH value during controlled mixing of Y(NO3)3 and NH4OH solutions has a significant effect on the structure of precipitated precursors. The anisotropy, lateral dimensions and intensity of crystallization of the plate-like particles decrease with increasing precipitation pH of precursors. It is established that the Y2O3 powders calcined at 700 °C result in a denser ceramic in comparison with the powders calcined at 1000 °C. A nearly transparent ceramics Y2O3 with a relative density of ∼98.5 % and grain size of ∼6 µm was synthesized by uniaxial pressing (P ∼ 374 MPa), followed by sintering at 1700 °C in vacuum for 4 hours.Synthesis of nanopowders and nearly transparent Y2O3 ceramics from yttrium hydroxynitrate (Y2(OH)5NO3•nH2O) precursors precipitated at constant pH from 7 to 10 was investigated. It is shown that the pH value during controlled mixing of Y(NO3)3 and NH4OH solutions has a significant effect on the structure of precipitated precursors. The anisotropy, lateral dimensions and intensity of crystallization of the plate-like particles decrease with increasing precipitation pH of precursors. It is established that the Y2O3 powders calcined at 700 °C result in a denser ceramic in comparison with the powders calcined at 1000 °C. A nearly transparent ceramics Y2O3 with a relative density of ∼98.5 % and grain size of ∼6 µm was synthesized by uniaxial pressing (P ∼ 374 MPa), followed by sintering at 1700 °C in vacuum for 4 hours.","PeriodicalId":418936,"journal":{"name":"PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115184540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}