Gaceta Mexicana de Oncologia最新文献_第7页

Incidencia de tumores malignos en pacientes adultos, diagnosticados por primera vez en el hospital Instituto de Seguridad y Servicios Sociales de los Trabajadores al Servicio de los Poderes del Estado de Puebla en el año 2014 2014年，普埃布拉州权力机构工作人员安全与社会服务研究所医院首次诊断出成人恶性肿瘤的发生率

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2016.02.005

Alma Mendoza López , Eduardo Téllez Bernal , Jacinto Christian Alonso Martínez , Fernando Silva Bravo , Francisco Herrera Calderón , Nora Marina Fernández Tamayo

{"title":"Incidencia de tumores malignos en pacientes adultos, diagnosticados por primera vez en el hospital Instituto de Seguridad y Servicios Sociales de los Trabajadores al Servicio de los Poderes del Estado de Puebla en el año 2014","authors":"Alma Mendoza López , Eduardo Téllez Bernal , Jacinto Christian Alonso Martínez , Fernando Silva Bravo , Francisco Herrera Calderón , Nora Marina Fernández Tamayo","doi":"10.1016/j.gamo.2016.02.005","DOIUrl":"https://doi.org/10.1016/j.gamo.2016.02.005","url":null,"abstract":"<div><p>The incidence of malignant tumours is increasing year by year, but no statistics are available nationwide. The purpose of this review is to raise awareness of the increase in the incidence of malignant tumours in adults during 2014, compared with 2013. In this article, an analysis was performed on the frequency of each type of tumour and its relationship to world literature, based on a count of patients throughout year 2013.</p></div><div><h3>Objective and methods</h3><p>To determine the incidence of malignant tumours in patients diagnosed in ISSSTEP for first time in 2014.</p><p>To achieve this goal, a register was compiled from the files of the department of pathology, and were reviewed to ensure that they were not recurrent tumours.</p><p>This register was approved by the head of department of the pathology institute.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 2","pages":"Pages 59-65"},"PeriodicalIF":0.1,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2016.02.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89997909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Resección guiada por fluorescencia en pacientes con cáncer de lengua 荧光引导舌癌患者切除

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2016.03.002

José Francisco Gallegos Hernández , Oscar Partida , Alma Lilia Ortiz Maldonado , Gerardo Gabriel Minauro Muñoz , Martín Hernández San Juan , Héctor Arias Ceballos , José Alberto Ábrego , Alejandra Mantilla Morales

{"title":"Resección guiada por fluorescencia en pacientes con cáncer de lengua","authors":"José Francisco Gallegos Hernández , Oscar Partida , Alma Lilia Ortiz Maldonado , Gerardo Gabriel Minauro Muñoz , Martín Hernández San Juan , Héctor Arias Ceballos , José Alberto Ábrego , Alejandra Mantilla Morales","doi":"10.1016/j.gamo.2016.03.002","DOIUrl":"https://doi.org/10.1016/j.gamo.2016.03.002","url":null,"abstract":"<div><h3>Background</h3><p>Fluorescence has been successfully used as screening method of oral cavity cancer. In addition to the conventional oral examination, it identifies areas with histological changes that are not identified with conventional white light.</p></div><div><h3>Objective</h3><p>To determine whether fluorescence facilitates resection with negative margins in patients diagnosed with squamous cell carcinoma of the tongue.</p></div><div><h3>Material and methods</h3><p>Patients diagnosed with invasive tongue squamous cell carcinoma were evaluated with a conventional oral examination and fluorescence. To determine whether the threshold of injury coincided in both tests, the limits of section were identified and histologically evaluated.</p></div><div><h3>Results</h3><p>The study included 30 patients, 18 women and 12 men; 10 T1, 15 T2, and 5 patients with T3. The neoplastic margin evaluated with conventional light coincided with fluorescence in 17 patients (56%), and in 13 (44%) fluorescence identified a larger tumour. Surgical margins were negative in 27 (90%), and 3 (10%) positives that were all in the tongue thickness and with bulky tumours (T3).</p></div><div><h3>Conclusions</h3><p>Fluorescence identifies larger tumours than those identified with conventional oral examination in 44% of patients, and ensures a longer surgical resection with free surgical margins in 90% of cases. Submucosal and muscular invasion is not detected by this method.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 2","pages":"Pages 66-69"},"PeriodicalIF":0.1,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2016.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91619625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Tumores limítrofes de ovario (experiencia con 50 casos)

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2015.12.012

Alfonso Torres Lobatón , Cecilio Alberto Jacobo González , Fred Morgan Ortiz

{"title":"Tumores limítrofes de ovario (experiencia con 50 casos)","authors":"Alfonso Torres Lobatón , Cecilio Alberto Jacobo González , Fred Morgan Ortiz","doi":"10.1016/j.gamo.2015.12.012","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.12.012","url":null,"abstract":"<div><h3>Introduction</h3><p>Borderline ovarian tumors are tumors with cell proliferation and nuclear atypia without stromal invasion, but with the ability to develop tumor implants, and recurrence probability up to 5 or more years after diagnosis.</p></div><div><h3>Objective</h3><p>To show the clinical and pathological aspects of diagnosis and treatment of these tumors through an institutional review of casuistry.</p></div><div><h3>Methods</h3><p>Retrospective analysis of clinical records from borderline ovarian tumors managed with oncologic criteria in the Department of Oncology at Hospital General de Mexico “Dr. Eduardo Liceaga”, for a period of 5 years.</p></div><div><h3>Results</h3><p>We treated 50 cases of 502 patients with epithelial ovarian cancer (9.9%); with a mean age of 45.8 years; the predominant clinical manifestations were pain and increased abdominal volume. Thirty-nine patients (78.0%) had serous tumors, 10 (20.0%) mucinous tumors; and 1 (2.0%) endometrioid tumor. Forty-one (82%) were classified in stage I; and 9 (18%) with stage II and III. Seventy one % of stage I and 88.8% of the stage II and III, had elevated Ca-125 (p>.05).</p><p>In 18 of 33 patients (54.5%) the correct diagnosis was obtained by intraoperative study. Thirty seven patients of the study were treated with radical surgery (74%) and 13, with conservative (but comprehensive) surgical staging (26%). Only one case of nine (11.1%) with restaging showed substratification; and 1 out of 30 lymphadenectomies (3.3%) had lymph node involvement. Twelve cases (24%) showed tumor implants. In this series, there was no tumor recurrence during a mean follow-up of 32.6 months.</p></div><div><h3>Conclusions</h3><p>Management with oncologic criteria of these tumors corroborated that the majority corresponds to Stage I, and helps reduce the numbers of recurrences. The role of lymphadenectomy is still controversial.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 2","pages":"Pages 70-77"},"PeriodicalIF":0.1,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.12.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91619624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tumor de células de la granulosa tipo juvenil 幼年型颗粒细胞肿瘤

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2016.03.006

Laura G. Carrillo Angeles , Dante Flores Hernández , José Manuel Aguilar Priego , Jorge Miguel García-Salazar

{"title":"Tumor de células de la granulosa tipo juvenil","authors":"Laura G. Carrillo Angeles , Dante Flores Hernández , José Manuel Aguilar Priego , Jorge Miguel García-Salazar","doi":"10.1016/j.gamo.2016.03.006","DOIUrl":"https://doi.org/10.1016/j.gamo.2016.03.006","url":null,"abstract":"<div><p>Granulosa cells tumours (CCT) are a heterogeneous group of neoplasms composed of cells derived from the gonadal sex cords, specialised gonadal stromal, and fibroblasts. They have an incidence of 0.5 to 1.6/100,000 cases per year. There are two histological types: adult (ACGT) and juvenile (JGCT), which show different histological and clinical characteristics. The juvenile variety is a rare entity, accounting for 5% of GCT, and usually occurs in premenarchal women and under 30 years of age. Two cases are presented of women under 30 years old with a diagnosis of juvenile granulosa cell tumour. The patient in Case no. 1 presented with a tumour of 20cm in the left iliac fossa, extending to upper quadrant of the same side. She underwent exploratory laparotomy with left salpingo-oophorectomy and an intra-operative study of the tumour. The patient in Case no. 2 received outpatient care, with our institution just performing a close monitoring. One year after oncological follow up, she obtained a healthy, live baby, without complications. It is concluded that the GCT remain a rare entity. In patients of childbearing age, conservative surgery such as unilateral oophorectomy can be performed, prior to excluding any extension outside the ovary and endometrial cancer. Survival in these patients is excellent, as most are in early stages.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 2","pages":"Pages 93-97"},"PeriodicalIF":0.1,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2016.03.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91619622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Ha perdido el oncólogo, autonomía de decisión en la práctica clínica? 肿瘤学家在临床实践中失去了决策自主权吗?

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2016.02.010

Francisco Javier Picó Guzmán , Francisco Javier Ochoa Carrillo

引用次数: 0

Mastografía por emisión de positrones: revisión de un promisorio instrumento diagnóstico 正电子发射乳腺造影:一种有前途的诊断仪器综述

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2016.03.004

Luis Azpeitia Espinosa , Mariana Bárbara Jiménez Bernal , Gisela Estrada Sánchez , Regina de la Mora Cervantes , José Luis Criales Cortés , María del Carmen Lara Tamburrino

引用次数: 0

Leucemia mieloide aguda con afectación neurológica y mamaria durante el embarazo. Reporte de un caso 妊娠期伴有神经和乳腺损伤的急性髓系白血病。报告个案

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Gaceta Mexicana de Oncologia Pub Date : 2016-03-01 DOI: 10.1016/j.gamo.2016.01.001

Mercedes del Pilar Álvarez-Goris , Juan Carlos Fuentes-Cobos , Nidia Carolina Espinosa Maldonado , Ricardo Sánchez Zamora , Angélica Ariadna Torres Aguilar , Ángel Augusto Pérez Calatayud , Jesús Carlos Briones Garduño

{"title":"Leucemia mieloide aguda con afectación neurológica y mamaria durante el embarazo. Reporte de un caso","authors":"Mercedes del Pilar Álvarez-Goris , Juan Carlos Fuentes-Cobos , Nidia Carolina Espinosa Maldonado , Ricardo Sánchez Zamora , Angélica Ariadna Torres Aguilar , Ángel Augusto Pérez Calatayud , Jesús Carlos Briones Garduño","doi":"10.1016/j.gamo.2016.01.001","DOIUrl":"https://doi.org/10.1016/j.gamo.2016.01.001","url":null,"abstract":"<div><p>The diagnosis of leukaemia is very rare during pregnancy, with a prevalence of 1:75,000 to 100,000 pregnant women. Around two-thirds are myeloid type, and it is characterised by a fast and lethal progression without early treatment. After early diagnosis, the chemotherapy should be established immediately to ensure the life of the mother. Although there are a few cases reports of good outcomes in second trimester, there are many adverse effects in the foetus in first trimester, making it a huge therapeutic dilemma. The patient will require interdisciplinary management, including haematology, obstetrics, and oncology. In particular they will also need to be informed about the importance in the timing of early chemotherapy and the inherent risks in pregnancy, as well as the risks of deciding not to interrupt it. The information on the diagnosis and treatment of acute myeloid leukaemia in pregnancy is limited in world literature.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 2","pages":"Pages 98-102"},"PeriodicalIF":0.1,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2016.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136991122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acrometástasis en astrágalo de adenocarcinoma endometrioide 子宫内膜样腺癌黄芪的顶转移

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Gaceta Mexicana de Oncologia Pub Date : 2016-01-01 DOI: 10.1016/j.gamo.2016.02.006

Miguel Ángel Clara-Altamirano, Dorian Yarih García-Ortega, Claudia Haydee Sarai Caro-Sánchez, Jorge Luis Martínez-Tlahuel, Héctor Martínez-Said, Mario Cuéllar-Hubbe

{"title":"Acrometástasis en astrágalo de adenocarcinoma endometrioide","authors":"Miguel Ángel Clara-Altamirano, Dorian Yarih García-Ortega, Claudia Haydee Sarai Caro-Sánchez, Jorge Luis Martínez-Tlahuel, Héctor Martínez-Said, Mario Cuéllar-Hubbe","doi":"10.1016/j.gamo.2016.02.006","DOIUrl":"https://doi.org/10.1016/j.gamo.2016.02.006","url":null,"abstract":"<div><h3>Introduction</h3><p>The term acrometastasis is given to those metastases distal to the elbows and knees. They are rare and account for only 0.1% of all metastatic bone lesions. Endometrioid adenocarcinoma (EA) is the most frequent in the female genital tract cancer in developed countries. Bone metastases are rare in EA.</p></div><div><h3>Case report</h3><p>A 57 year old female 57 years presenting with trans-vaginal bleeding (TVB). The ultrasound and endometrial biopsy reported a moderately differentiated AE. This was initially treated with a hysterectomy, bilateral pelvic and para-aortic lymphadenectomy plus 50.4Gy external radiotherapy, and intracavitary brachytherapy. Six months later she complained of pain in left ankle and inability to walk. Computed tomography showed an expansive lytic lesion, predominantly in the talus. As the bone biopsy reported a moderately differentiated metastatic endometrioid adenocarcinoma, treatment is initiated with radiotherapy of 30Gy. Support was deferred and palliative chemotherapy started with paclitaxel and carboplatin in six cycles, as well as monthly application of zoledronic acid. Currently, after twelve months follow-up the patient has made good progress, with pain in left ankle, and tolerating walking.</p></div><div><h3>Conclusion</h3><p>The treatment strategy in patients with isolated acrometastasis remains controversial, and there are few cases described in the literature. External radiotherapy is usually considered as treatment of choice for these lesions. Acrometastasis is rare but should be taken into account in patients with cancer, who have unexplained severe pain in hands and feet.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 1","pages":"Pages 43-46"},"PeriodicalIF":0.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2016.02.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137268275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Acrometástasis en miembro inferior por adenocarcinoma pulmonar 肺腺癌引起的下肢肢肢转移

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Gaceta Mexicana de Oncologia Pub Date : 2016-01-01 DOI: 10.1016/j.gamo.2016.02.001

Elena Espinosa Muñoz, Diego Ramírez Ocaña, Ana María Martín García, Carmen Puentes Zarzuela

引用次数: 1

Disminución de mortalidad en hemopatías malignas con un nuevo método de acondicionamiento para trasplante alogénico mieloablativo 异体骨髓消融移植新调理方法降低恶性血液病死亡率

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Gaceta Mexicana de Oncologia Pub Date : 2016-01-01 DOI: 10.1016/j.gamo.2016.02.002

Eucario León Rodríguez, Mónica M. Rivera Franco

{"title":"Disminución de mortalidad en hemopatías malignas con un nuevo método de acondicionamiento para trasplante alogénico mieloablativo","authors":"Eucario León Rodríguez, Mónica M. Rivera Franco","doi":"10.1016/j.gamo.2016.02.002","DOIUrl":"https://doi.org/10.1016/j.gamo.2016.02.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Allogeneic stem cell transplantation (ASCT) is the ideal treatment for haematological malignancies. However, the morbidity and mortality associated with the procedure limit its use.</p></div><div><h3>Objectives</h3><p>To describe clinical characteristics, toxicity, and survival of adult Mexican patients undergoing ASCT using busulfan with a reduced dose of cyclophosphamide (BUCY 2) as a conditioning method.</p></div><div><h3>Methods</h3><p>A prospective cohort study was conducted from October 1999 to December 2014, by performing an analysis of clinical characteristics, complications, and survival of 35 patients using this conditioning regimen.</p></div><div><h3>Results</h3><p>The study included 35 patients undergoing ASCT with reduced BUCY 2. All of them had an HLA-matched related donor, with a median age of 33 years (range 16-49), and 60% were male. The patients had the following underlying diseases: myelodysplastic syndrome in 14 patients (40%), chronic myeloid leukaemia in 9 (25.7%), acute leukaemia in 10 (23.5%), and paroxysmal nocturnal haemoglobinuria in 2 (5.7%). The median of transfused CD34+cells was 2.04×10<sup>6</sup>/kg. The median time to neutrophil and platelet recovery was 21 and 18 days, respectively. The most common toxicity was mucositis (91.4%). Transplant related mortality was 5.7%, and 5-year overall survival was 72.5%.</p></div><div><h3>Conclusions</h3><p>The conditioning method described earlier preserves a cytotoxic effect allowing eradication of the malignant clone, and achieving a graft with acceptable toxicity, and low transplant related mortality, representing a good alternative for ASCT.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"15 1","pages":"Pages 16-21"},"PeriodicalIF":0.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2016.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137268278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1