Gaceta Mexicana de Oncologia最新文献_第10页

Semblanza del M. C. Ramiro Jesús Sandoval M. C. 拉米罗-赫苏斯-桑多瓦尔简介

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Gaceta Mexicana de Oncologia Pub Date : 2015-11-01 DOI: 10.1016/j.gamo.2015.12.009

Enrique Ávila Monteverde , Pedro Mario Escudero de los Ríos

引用次数: 0

Cáncer oral en un hospital general de zona del Instituto Mexicano del Seguro Social en México, (1988-2005) 墨西哥社会保障研究所综合地区医院的口腔癌(1988-2005)

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Gaceta Mexicana de Oncologia Pub Date : 2015-11-01 DOI: 10.1016/j.gamo.2015.11.011

Gustavo Sergio Moctezuma-Bravo , Ricardo Díaz de León-Medina , Francisco Javier Rodríguez-Quilantan , Mariana Moctezuma-Dávila

{"title":"Cáncer oral en un hospital general de zona del Instituto Mexicano del Seguro Social en México, (1988-2005)","authors":"Gustavo Sergio Moctezuma-Bravo , Ricardo Díaz de León-Medina , Francisco Javier Rodríguez-Quilantan , Mariana Moctezuma-Dávila","doi":"10.1016/j.gamo.2015.11.011","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.11.011","url":null,"abstract":"<div><p>The diagnosis and treatment of oral diseases, both benign and malignant is part of the activities of the maxillofacial surgeon.</p></div><div><h3>Objective</h3><p>Report histopathogically confirmed cases of oral cancer.</p></div><div><h3>Material and methods</h3><p>Type of study: observational and descriptive.</p></div><div><h3>Design</h3><p>Transversal, retrospective, from January 1989 to December 2005, of all diagnoses recorded in the Department of Pathology of the hospital's second level health care General Hospital Zone of the Mexican Social Security Institute in San Luis Potosi, Mexico, where maxillofacial surgery service is located. Study subjects: all diagnoses obtained by histological study of biopsies performed on patients from the CMF was included. Type and sample size: 1,211 consecutive cases. Study variables; histological diagnosis, gender and age of the patient. Descriptive statistics with measures of central tendency and dispersion. Ethical considerations approval of the Local Committee of Institutional Research.</p></div><div><h3>Results</h3><p>Biopsies for histology received by the Department of Pathology in the 17 years (1989-2005) were 34 118 specimens, 1,211 cases (3.5%) were sent by maxillofacial surgery and 53 cases of cancer; 31 carcinomas, 10 malignant salivary gland tumors, sarcomas and lymphomas 12.</p></div><div><h3>Conclusion</h3><p>Oral cancer diagnosed by histological study of insured population of the Social Security System in Mexico contributing to increasing knowledge of the same in the Mexican population is reported.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"14 6","pages":"Pages 323-328"},"PeriodicalIF":0.1,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.11.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136916995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

El cáncer gástrico en una institución de tercer nivel: correlación endoscópica, por tomografía computarizada e histopatológica del cáncer gástrico en el Hospital Central Militar 第三层次机构的胃癌:中央军事医院胃癌的内镜、计算机断层扫描和组织病理学相关性

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.003

Gaspar Alberto Motta-Ramírez , Francisco Eduardo Almazán-Urbina , Mariana Aragón-Flores , Javier Bastida-Alquicira , Emmanuel Itzcóatl Luján-Cortés , Raúl Gámez Salas

{"title":"El cáncer gástrico en una institución de tercer nivel: correlación endoscópica, por tomografía computarizada e histopatológica del cáncer gástrico en el Hospital Central Militar","authors":"Gaspar Alberto Motta-Ramírez , Francisco Eduardo Almazán-Urbina , Mariana Aragón-Flores , Javier Bastida-Alquicira , Emmanuel Itzcóatl Luján-Cortés , Raúl Gámez Salas","doi":"10.1016/j.gamo.2015.11.003","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.11.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Cancer is the third cause of death in Mexico, and is the second cause of malignant tumour-related mortality, with an incidence that has not declined over the last decades.</p></div><div><h3>Material and Methods</h3><p>The study included patients who were studied by endoscopy and CT using any protocol due to clinical suspicion of primary gastric tumour lesion in the period from 1 May 2011 to 2 March 2015. Primary gastric tumour diagnosis, as well as other alternative diagnoses, was established by histopathology.</p></div><div><h3>Results</h3><p>The study included 45 patients, of whom, 28 were male (62%) and 17 were female (38%). Ages ranged from 32 to 86 years. The most common clinical reason was constitutional syndrome, either alone or associated with other clinical symptoms in 18 patients (40%). The gastric cancer was histopathologically confirmed in 30 patients (66%), with 16 (53%) being detected late, with peritoneal carcinomatosis (PC) in 13 (43%), 3 of them with liver metastasis (LM), 1 with venous thrombosis (VT), 2 with LM, and 1 with VT. The gastric CT protocol, with and without contrast-enhanced thoracic images, was performed in 12 patients (27%). Gastric folds thickening was detected in 20%, with concentric gastric thickening in 48% and associated with an ulcerated lesion, PC, LM and VT in 32%. No patients were detected early.</p></div><div><h3>Conclusions</h3><p>Gastric distension is critical in abdominal imaging and gastric CT represents the ideal imaging technique for gastric cancer staging and classification. The association between constitutional syndrome and gastric cancer reached an elevated rate, with gastric CT being recommendable for the diagnostic approach.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"14 5","pages":"Pages 231-241"},"PeriodicalIF":0.1,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.11.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136997181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Sarcoma pleomórfico indiferenciado renal primario: reporte de caso y revisión de la literatura 原发性肾未分化多形性肉瘤:病例报告和文献综述

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.008

Milagros Abad-Licham , Daniel Carbajal-Vásquez , Patricia Coral-González , Teresa Cusma-Quintana , Eloy Silva-Capuñay , Juan Astigueta-Pérez

引用次数: 0

Radioterapia en mielofibrosis ganglionar refractaria a la terapia dirigida 靶向治疗难治性淋巴结骨髓纤维化的放疗

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.006

Abril Antonia Quézada-Bautista , María Yicel Bautista-Hernández

{"title":"Radioterapia en mielofibrosis ganglionar refractaria a la terapia dirigida","authors":"Abril Antonia Quézada-Bautista , María Yicel Bautista-Hernández","doi":"10.1016/j.gamo.2015.11.006","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.11.006","url":null,"abstract":"<div><p>Primary myelofibrosis is a disease of the bone marrow characterized by fibrosis, associated with splenomegaly and extramedullary haematopoiesis. In peripheral blood, a pattern of leucoerythroblastosis and tear drop cells, as well as elevated levels of pro-inflammatory and angiogenic cytokines is observed.</p><p>There are two types: primary myelofibrosis, which is not associated with any bone marrow condition, and secondary disease, which is associated with myeloproliferative syndrome conditions such as essential thrombocytosis or polycythaemia vera.</p><p>The incidence in the United States ranges from 0.21 to 0.25 cases per 100 thousand inhabitants, it is associated more often with the male gender, and mean age at diagnosis is 67 years.</p><p>The treatment of primary myelofibrosis can be in different forms, depending on the goal of treatment, with curative or palliative intent. Treatment modalities include surgical procedures with splenectomy, pharmacological treatment with drugs to produce cell inhibition such as hydroxycarbamide, immunomodulators such as thalidomide, or targeted therapy such as ruxolitinib; radiation therapy is generally used to treat medical treatment-refractory splenomegaly or in those patients with any surgical contraindication and, finally, bone marrow transplantation has proven to be the only treatment that modifies survival.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"14 5","pages":"Pages 268-272"},"PeriodicalIF":0.1,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.11.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136997398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuberculosis genital-peritoneal, la simuladora de cáncer de ovario. Reporte de un caso 生殖器-腹膜结核，卵巢癌模拟器。报告个案

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.007

Mercedes del Pilar Álvarez-Goris , Francisco Javier Ochoa Carrillo , Ricardo Sánchez Zamora , Ángel Augusto Pérez-Calatayud , Angélica Ariadna Torres Aguilar , Jesús Carlos Briones Garduño

引用次数: 0

Factores pronósticos de recurrencia y supervivencia en tumores del estroma gastrointestinal. Experiencia del Hospital de Oncología Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social 胃肠道间质肿瘤复发和生存的预后因素。墨西哥社会保障研究所21世纪国家医学中心肿瘤医院的经验

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.002

Rafael Medrano Guzmán , Nelly Kinakú Meza Bautista , Juan Rodríguez Silverio , Gabriel González Ávila

{"title":"Factores pronósticos de recurrencia y supervivencia en tumores del estroma gastrointestinal. Experiencia del Hospital de Oncología Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social","authors":"Rafael Medrano Guzmán , Nelly Kinakú Meza Bautista , Juan Rodríguez Silverio , Gabriel González Ávila","doi":"10.1016/j.gamo.2015.11.002","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.11.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Gastrointestinal stroma tumours are mesenchymal lesions derived from Cajal interstitial cells. The most effective treatment in primary localised disease is surgery. With imatinib as neoadjuvant treatment in high-risk lesions or metastatic disease, 5-year survival has increased to nearly 80%. The purpose of this work is to analyse prognostic factors that determine recurrence and disease-free survival in this type of tumour.</p></div><div><h3>Material and methods</h3><p>Observational, retrospective, longitudinal study of patients from the Oncology Hospital, CMN Siglo XXI, with histological confirmation and surgical treatment of the primary lesion.</p></div><div><h3>Results</h3><p>Sixty-six patients were identified. The most common tumour site was the stomach (66.6%), followed by small bowel (28.7%), and colon (1.54%). At the time of diagnosis, 7.57% had metastasis: 4.54% (3) in the liver and 3.03% (2) in the peritoneum. The mean size of tumours was 10.84cm (2.2 to 38cm). Overall 5-year survival was 82%, and 5-year recurrence-free survival was 61%. In the case of overall survival, the site of the lesion was the only factor showing statistical significance, with <em>P</em>  <!-->.0054.</p></div><div><h3>Conclusion</h3><p>Tumour location and size, number of mitoses, risk group, and adjuvant treatment with imatinib were statistically significant as prognostic factors of disease recurrence. Lesion location was the only factor that showed statistical significance as a prognostic factor of overall survival.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"14 5","pages":"Pages 259-267"},"PeriodicalIF":0.1,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.11.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136997399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Metilación del ADN en el mieloma múltiple 多发性骨髓瘤中的dna甲基化

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.09.002

Pavel Romero-Espinoza , Esperanza Barrera-Chairez , Patricio Barros-Núñez

引用次数: 0

Cáncer de mama con receptores hormonales positivos: tratamiento adyuvante, primera línea en cáncer metastásico y nuevas estrategias (inhibición de mTOR) 激素受体阳性乳腺癌:辅助治疗，转移性癌症的一线治疗和新策略(mTOR抑制)

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.001

Iván Romarico González Espinoza , Cynthia Villarreal Garza , Oscar Alfredo Juárez León , Luis Alfonso Adel Álvarez , Juan Carlos Cruz López , Eduardo Téllez Bernal

{"title":"Cáncer de mama con receptores hormonales positivos: tratamiento adyuvante, primera línea en cáncer metastásico y nuevas estrategias (inhibición de mTOR)","authors":"Iván Romarico González Espinoza , Cynthia Villarreal Garza , Oscar Alfredo Juárez León , Luis Alfonso Adel Álvarez , Juan Carlos Cruz López , Eduardo Téllez Bernal","doi":"10.1016/j.gamo.2015.11.001","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.11.001","url":null,"abstract":"<div><p>Breast cancer is known to be the most commonly diagnosed malignancy and the main cause of death in women worldwide. Several studies have demonstrated that most these cancers are positive for estrogen and/or progesterone receptors, which represent a constant risk for late recurrence. Hormone therapy has been the first systemic treatment that has proven to be effective in patients who express positive hormone receptors. Until recent years, tamoxifen and ovarian suppression were the best hormone therapies available both for adjuvance and advanced disease. Aromatase inhibitors, as well as the new mTOR pathway inhibitors, have driven an important advance in the treatment of breast cancer by improving survival and disease-free interval for these patients. In this article, we make a review of these treatments and the studies that have supported them, as well as their potential adverse effects.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"14 5","pages":"Pages 277-292"},"PeriodicalIF":0.1,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.11.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136997372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Impacto de la obesidad en el pronóstico de supervivencia y recaída en niños con leucemia aguda linfoblástica del estado de México 在墨西哥，肥胖对急性淋巴母细胞白血病儿童生存和复发预后的影响

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Gaceta Mexicana de Oncologia Pub Date : 2015-09-01 DOI: 10.1016/j.gamo.2015.11.004

Norma Araceli López Facundo , Isidoro Tejocote Romero , Cecilia Rodríguez Castillejos , Yanet Jaimes García

{"title":"Impacto de la obesidad en el pronóstico de supervivencia y recaída en niños con leucemia aguda linfoblástica del estado de México","authors":"Norma Araceli López Facundo , Isidoro Tejocote Romero , Cecilia Rodríguez Castillejos , Yanet Jaimes García","doi":"10.1016/j.gamo.2015.11.004","DOIUrl":"https://doi.org/10.1016/j.gamo.2015.11.004","url":null,"abstract":"<div><h3>Introduction</h3><p>In Mexico, childhood cancer and obesity are public health problems. Malnutrition, but not obesity, has been associated with a lower probability of survival and increased risk of relapse.</p></div><div><h3>Objective</h3><p>To assess the impact of obesity on the prognosis of survival and relapse in children with Acute Lymphoblastic Leukaemia (ALL).</p></div><div><h3>Material and methods</h3><p>Children with ALL were included in a cohort. An assessment was made of the nutritional status at diagnosis, according to BMI values in children, searching for an association of obesity and other factors with disease relapse and survival using Kaplan-Meier curves and Cox regression.</p></div><div><h3>Results</h3><p>A total of 161 patients were studied, of which 70% were males with obesity, and of these, 43% had very high risk ALL. Obesity increased the risk for relapse (OR: 3.6; 95% CI: 1.7-7.6, <em>p</em>=.001) and death (OR: 3.4; 95% CI: 1.51-7.48, <em>p</em>=.002), and limited 77-month survival to 52%. An Exp β of 3.35 was obtained in the Cox regression for patients with obesity and a very high risk leukaemia.</p></div><div><h3>Discussion</h3><p>Obesity influences the prognosis of relapse and survival time, due to a considerable increase in toxicity and some growth factors that induce chemoresistance in neoplastic cells. Biological factors influencing the prognosis of the disease may not be modifiable; however, it is essential to establish health policies aimed at early diagnosis, as well as at obesity and overweight prevention.</p></div>","PeriodicalId":41581,"journal":{"name":"Gaceta Mexicana de Oncologia","volume":"14 5","pages":"Pages 242-249"},"PeriodicalIF":0.1,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.gamo.2015.11.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136997180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1