Tumor de células de la granulosa tipo juvenil

Granulosa cells tumours (CCT) are a heterogeneous group of neoplasms composed of cells derived from the gonadal sex cords, specialised gonadal stromal, and fibroblasts. They have an incidence of 0.5 to 1.6/100,000 cases per year. There are two histological types: adult (ACGT) and juvenile (JGCT), which show different histological and clinical characteristics. The juvenile variety is a rare entity, accounting for 5% of GCT, and usually occurs in premenarchal women and under 30 years of age. Two cases are presented of women under 30 years old with a diagnosis of juvenile granulosa cell tumour. The patient in Case no. 1 presented with a tumour of 20 cm in the left iliac fossa, extending to upper quadrant of the same side. She underwent exploratory laparotomy with left salpingo-oophorectomy and an intra-operative study of the tumour. The patient in Case no. 2 received outpatient care, with our institution just performing a close monitoring. One year after oncological follow up, she obtained a healthy, live baby, without complications. It is concluded that the GCT remain a rare entity. In patients of childbearing age, conservative surgery such as unilateral oophorectomy can be performed, prior to excluding any extension outside the ovary and endometrial cancer. Survival in these patients is excellent, as most are in early stages.