Journal of Complementary Medicine Research最新文献

{"title":"Prevalence of non-adherence to medications in people with type 2 Diabetes mellitus","authors":"F. Alfhaid, Mansour Alzahrani, H. Alzahrani, M. Aljulifi, A. Alqabbani, N. Alzaidy, A. Almutairi, S. Alsaadoon","doi":"10.5455/jcmr.2023.14.01.21","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.21","url":null,"abstract":"Diabetes mellitus (DM) is a chronic, non-communicable disease that has an increasing incidence rate over time as well as increasing disease-related deaths. Furthermore, around half of diabetic patients are unaware actually about their disease, and more are not taking their medications. This study aimed to determine the extent of medication adherence and factors contributing to non-adherence among diabetic patients in Majmaah governance, Saudi Arabia. This is an observational cross-sectional study design conducted among patients with type 2 diabetes. A self- administered questionnaire was distributed among diabetic patients .The questionnaire consisted of socio- demographic data, HbA1c level, duration of DM, family history of DM, DM medications and 12-Item Medication Adherence Scale. 180 patients with diabetes type 2 were involved (71.7% females vs. 28.3% males). The prevalence of patients with uncontrolled HbA1c levels was 25%. Family history of DM constitutes 74.4%. The most preferred route for drug administration was oral (50.6%). High non-adherent to medication was found among 57.8%. The independent significant factor associated with high non-adherence to DM medication was uncontrolled HbA1c while being a female was the independent significant factor for low non-adherent to DM medication. The non-adherent of the diabetic patients regarding anti-diabetes medications was widely prevalent. Female patients tend to be more adherent to DM medication than their male counterparts. This study established the fact that uncontrolled glycated hemoglobin was a detrimental factor in adherence to anti-DM medications. More studies are required to raise the awareness of the diabetic population regarding the importance of medication adherence.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86673511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Nematicidal Activity of Moringa Oleifera Leaves Extract Against Gastro-Intestinal Strongyles of Small Goats","authors":"M. Gertrude, Yondo Jeannette, T. Gabriel, N. Stephanie, M. Mbida","doi":"10.5455/jcmr.2023.14.01.30","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.30","url":null,"abstract":"Introduction: Gastrointestinal nematodes have a deleterious effect on animal health and production. In search of alternative to synthetic anthelminthics in the control of strongylosis among small ruminants, this study was conducted to evaluate the in situ adulticidal properties of Moringa oleifera on gastro-intestinal strongyles of goats. Methods: Twenty (20) goats naturally infested with mixed gastrointestinal nematodes were distributed into 5 groups (n=4): a negative control group receiving Tween 80 at 2.8%, a positive control group treated with Albendazole at 5 mg/kg and tested groups treated with doses of extract (125, 250 and 500 mg/kg). In situ anthelminthic activity was assessed through determination of the faecal eggs count reduction, total worm count reduction, variation of packed cell volume (PCV) and body weight after treatment. Results: Five species of nematodes were identified among experimental animals, with Strongyloides papillorus as the most prevalent (93.8%) followed by Haemonchus contortus (87.5%). At dose of 500 mg/kg, ethanolic extract of M. oleifera registered 76.4 % and 69.8 % eggs density reduction of gastro-intestinal strongyles eggs and parasitic load nineteen days post-treatment respectively while Albendazole induced 100 % reduction of these same parameters at the dose of 5 mg/kg. Moreover, the extract did not significantly affect PCV nor body weight of experimental goats. Conclusion: This study validates scientifically the use of alcoholic leaves extract of M. oleifera in the treatment of gastro-intestinal strongyles. The standardization of this extract is however necessary for his use as a sustainable tool for controlling strongylosis in small ruminants.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81714608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of The Relationship between The Pesticide Fluopyram and Parkinson’s disease","authors":"Hanan Sammarraie, Nurten elik, Dilek elik, G. rel, brahim Onaran, No author No author, P. Ar, Meltem men","doi":"10.5455/jcmr.2023.14.01.01","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.01","url":null,"abstract":"Parkinson's disease (PD) is a neurodegenerative disease defined as a shaky stroke. It is clinically characterized by; resting tremor, cogwheel rigidity, bradykinesia, and postural reflex impairment. It is also pathologically characterized by Lewy bodies (LBs) and formed by the loss of dopaminergic neurons in the Substantia nigra pars compacta (SNpc) region of the brain and the accumulation of AlphaSynuclein (α-Syn) proteins. Pesticides are the hugest risk factor of PD. They cause the formation of PD by using different mechanisms. They also permanently disrupt the function of the electron transport complex (ETC) located in the mitochondria. Researches show that the pesticide Rotenone (ROT) causes PD in vivo and in vitro conditions by inhibiting mitochondrial complex I and causing oxidative stress. Fluopyram (Flu) is a frequently used pesticide that causes mitochondrial toxicity like ROT. When literature is searched, it makes one think about a connection with PD. it seems that there is no available study on Flu and PD. Flu is one of the fungicides utilized in Isparta city at a high rate for all planting types. The Flu is a mitochondrial complex II inhibitor. The inhibition of mitochondrial complexes is the main pathway in the PD mechanism, therefore complex II inhibitor pesticide may lead to the same result. In this context, we created a Parkinson's model in mice with ROT and compare the result of Flu with this ROT to be sure whether that lead to Parkinson's or not. Swiss albino male and female mice were the testing animals of our study. Positive control (ROT Parkinson model, 1 mg/kg/day), negative control (Solvent only, DMSO), and Flu (0.5,1 and 2 mg/kg/day) were administrated to mice daily doses subcutaneously (SC). The experiment got completed after 21 days. Motor Function Test, Histochemical and Immunohistochemical Studies, Comet assay, and quantitative real-time PCR (qRT-PCR) were utilized in the study as well. In our results, no statistically significant changes were observable in animal weights in all groups. In the motor function test, a significant decrease in the ROT group was observable, On the other hand, a significant decrease was detected specifically in the Flu value which was applied at high doses. When the brain tissues that belong to the ROT and Flu tested groups got examined, all-important structural changes such as LBs got observed in the SN. When brain tissues belonging to ROT and Flu groups were examined in α-Syn immunohistochemical staining, more positive markings were observable. When the brain tissues belonging to the ROT and Flu groups were examined in Tyrosine hydroxylase (TH) immunohistochemical staining, fewer positive markings were observed. ROT has been found to cause DNA damage in blood and brain tissues. It has been determined that groups with Flu applied in the brain do not have DNA damage. ROT was observed to increase SNCA mRNA expression levels while decreasing TH and DJ-1 mRNA expression levels. Comparing the Fl","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89485981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Challenges of Modern Era: Cardiovascular Diseases at The Beginning of XXI Century","authors":"E. Korableva, T. Bocharova, Lidia Sklyar, V. Shakolyukova","doi":"10.5455/jcmr.2023.14.03.01","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.01","url":null,"abstract":"At the beginning of XXI century cardiovascular diseases continue to be the most significant problem for modern medicine as the field of theoretical scientific knowledge, practical medicine, social, economic and domestic political spheres of activity in most countries of the world, and against the background of the outbreak of modern pandemics they have taken on the outlines of serious challenges to humanity, its viability. Particular attention is drawn to the fact that the population of the whole world feels the consequences of cardiovascular diseases expressed in the steady disability of the adult population, demographic decline, low life expectancy and high mortality rates. As analyzed in the article, these facts have become a serious basis for finding the ways to combat cardiovascular diseases on a global scale coordinating the actions and efforts of different countries in a single common task. In the work the author focuses the main attention on how important it is to convey the message to the international community that the problem of cardiovascular diseases is not only a strictly medical one and that it is beyond the power of healthcare organizations to solve it alone, even having mobilized all their capabilities. The purpose of the research:To create a general picture of cardiovascular pathology in the modern world as a global social problem in order to find ways to correct the activities of national and international health organizations, as well as non-medical organizations to combat heart pathologies.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77587006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Refractive Errors Among Saudi Population: A Systematic Review and Meta-Analysis","authors":"Majid Moafa","doi":"10.5455/jcmr.2023.14.03.04","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.04","url":null,"abstract":"Background: Refractive errors are common globally with an estimated number of 2.3 billion people suffering from impaired vision secondary to uncorrected refractive errors. This study aimed to estimate a piece of proper evidence about the overall prevalenceof refractory errors within the kingdom. Methods: A process of collection of relevant key words was conducted followed by database search. All data were analyzed with R software version 4.0.2. Using a “meta” package. The event rate and the corresponding 95% confidence interval (CI) was used to assess the prevalence of refractive errors in the study. Results: The sample size was 16850 individual with the highest sample size was 5176 and the lowest one was 162. The male prevalence in our sample was 55%. All the included papers were published after 2010 and were of fair quality. Eleven studies of 12,121 individuals reported the overall prevalence of different refrative erros. The pooled overall prevalnce rate was 27.28% (95% CI= 18.29-40.69) (Figure 2A); ranging from 4.55% to 72.20% among individual studies. This wide range of the reported prevalence rates was evident with a significant heterogenity among the included studies (I2= 99%; P-value< 0.001). Conclusion: A huge part of the high rates might be attributable to medical students. Moreover, myopia was the most common refractive error followed by astigmatism and hyperopia.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87758292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyphenols as bioactive food components in relation to autism spectrum disorders: An overview of the literature","authors":"B. Alahmadi","doi":"10.5455/jcmr.2023.14.03.30","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.30","url":null,"abstract":"Autism spectrum disorder (ASD) known as a set of behavioral and neurocognitive problems that are identified by challenges in difficulties interacting and communicating with others, as well as heightened repetitive and/or restrictive behaviors. Elevated immune reaction and enhancements in pro-inflammatory cytokines have been discovered in the brains of those who have ASD. A recent article associated autism with abnormalities in mitochondrial respiratory control. Based on various studies, mitochondrial dysfunction is caused by oxidative stress, inadequate nutrition, insufficiency of vitamins, compromised immune system, contact with harmful environmental substances, and modified calcium signaling. Polyphenols found in our diet are active compounds that have the potential to prevent and treat various chronic illnesses including, neurodegenerative and neurodevelopmental problems. This is mainly due to their ability to regulate crucial pathways that cause inflammation and oxidation in the body. The application of polyphenols may result in a reduction of neuroinflammation, facilitating an improvement in the manifestations of ASD. This review focused on the preclinical and clinical studies that documented the beneficial impacts of diet related for the modulation of ASD.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86110717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing Stress Of Nurses Through Their Efficiencies And Commitment: An Empirical Investigation","authors":"S. Alflayyeh, Maha Almujalli","doi":"10.5455/jcmr.2023.14.03.07","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.07","url":null,"abstract":"It has been determined that nursing is a profession with high levels of stress. Not only did nurses' health suffer because of the stress of their jobs, but they also struggled to cope with the demands of their jobs. This study aimed to figuring out how to manage nursing shifts to avoid Work-related Stress and haw to control and manage nursing works to avoids work-related stress in nursing, which can affect it. according to some independent variables such as the type of nurse, the scientific qualification, the type of hospital, the social situation, and the age group. The researchers selected a sample of (168) nurses who work in private clinics. Collected data was analyzed through SPSS version 22. Findings shows that all the considered constructs are having a strong relationship.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85389643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 on Smoking Behaviour Majmaah University, Saudi Arabia","authors":"R. Alzahrani, Bandar Alsaadoon, Abdulaziz Almasaudi, Murad Almutairi, Majeed Alanazi, Mohamad Alolah","doi":"10.5455/jcmr.2023.14.01.09","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.01.09","url":null,"abstract":"The main aim of this study was to evaluate the impact of Covid-19 pandemic on the smoking behavior among the people of Majmaah University. This Cross sectional study was conducted in Majmaah city from September 2020 to June 2020. It was an observational study and a total of 180 people were included in this. The inclusive criteria of this study was smoker male and female population. Online questionnaire was used to collect data. Out of total 180, 91 % population comprised of men and females were 8.9 %. The results of this study stated that 88.9 % people were active smokers. Cigarette was the most common form of tobacco consumption, 71.1 %. During the Covid-19 pandemic, almost 40 % of the participants decreased smoking and 35.6 % increased smoking. While after the pandemic ended 35.6 % of the participants increased smoking and 26.1 % decreased. There was a significant association between the current use of tobacco/nicotine and gender, with p value being less than 0.05. There was also significant association between knowledge of severely affect the lung and respiratory system and gender, with p value being less than 0.05. This study concluded that the Covid-19 pandemic lockdown affected the smoking behavior of many people in Saudi Arabia. Majority of people decreased smoking during the pandemic. On the other hand, majority of the people increased smoking after the pandemic ended. The results of this study indicated the need of awareness among the people regarding smoking and its side effects so that healthy living could be promoted among the masses. This would eventually lead to a healthy society and boost in immunity of the people in such a way that health related crisis could be easily fought in the future. Covid-19 provided a good opportunity for people to quit smoking.","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89418117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Management of Post-Extraction Complications","authors":"M. Assiry, Mohammed M. Aloqbi, H. Albrahim, Abdulaziz K. Alnabulsi, Hala Alim, Maisa Ghamdi, Lojain Bassyoni","doi":"10.5455/jcmr.2023.14.02.14","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.02.14","url":null,"abstract":"Introduction: Simple tooth extraction is one of the most common procedures performed by general dentists and Oral and Maxillofacial surgeons throughout daily practice. However, although it is a simple procedure, tooth-related complications could occur at any time. These complications are categorized into immediate and delayed complications. Immediate complications are due to either tooth-related or dentist-related factors and require prompt actions and immediate management. Tooth-related factors depend on tooth morphology and tooth structure conditions. Dentist-related factors depend on the proper selection and application of the instruments. On the other hand, delayed complications might occur after two days or more following the extraction. Objective: To evaluate the prevalence, prediction of risk factors complications, prevention and management of possible immediate and delayed post-extraction complications occurring in our Oral Surgery clinics at King Abdulaziz University Dental Hospital. Method: An observation and assessment of the extraction procedure, data collected via validated survey were used to gather the following: Demographic data, medical history, cause of extraction, number of tooth/teeth extracted, complications if any, and who did the procedure. For each patient who underwent dental extraction, a survey was filled out, by a doctor other than the operator and the procedure was assessed under observation to record any complications that occurred during the procedure and assess the undertaken management in such a case without intervention. Data was analyzed using Chi-square test through SPSS. Result: We observed 172 extraction procedures with 160 different patients, 12 had extraction more than once. A total 350 teeth were extracted from 160 patients, we observed 92 complications (53.4%) between immediate and delayed, 7 patients had both, the most common immediate complication was soft tissue injury with (81.7%) 67/82, and for the delayed complications the most common was dry socket (64.7%) 11/17 patients. Conclusion: In conclusion, we found a significant association between the number of post-operative complications, their management, and the experience of the operator","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76668103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Approaches to The Treatment of Chronic Diseases: Prospects for The Use of Innovative Methods and Technologies in Medicine","authors":"Dmitry Zemel, Saida Saadulaeva, Ekaterina Chikisheva, N. Kashentseva, A. Boldyrev, Georgiy Aramyanc","doi":"10.5455/jcmr.2023.14.03.10","DOIUrl":"https://doi.org/10.5455/jcmr.2023.14.03.10","url":null,"abstract":"This article examines current approaches to the treatment of chronic diseases and prospects for the use of innovative methods and technologies in medicine. The paper presents an overview of modern methods of treatment of chronic diseases, such as drug therapy, exercise, diet and lifestyle changes. New methods are also being considered, such as the use of technologies related to AI, biotechnology, gene therapy, nanotechnology, etc. In addition, the authors describe how these methods can help in more accurate diagnosis and the choice of individual treatment for the patient. The article also discusses the advantages and disadvantages of each method, as well as the potential risks and ethical issues associated with their use. The authors conclude that the use of innovative methods and technologies can significantly improve the effectiveness of treatment of chronic diseases and improve the quality of life of patients, but also requires additional research and regulation by medical organizations and governments. One of the most promising areas in the treatment of chronic diseases is the use of AI and machine learning. These technologies can help in more accurate diagnosis, selection of individual treatment, monitoring of the patient's condition and prediction of possible complications. Biotechnologies also provide new opportunities in the treatment of chronic diseases. For example, the use of therapeutic proteins and gene therapy can be effective in the treatment of certain forms of cancer, cystic fibrosis and other diseases. Nanotechnology may also have significant potential in the treatment of chronic diseases. Nanoparticles can be used to deliver drugs to specific places in the body and to diagnose early stages of diseases. However, it should be borne in mind that the use of innovative methods and technologies is also associated with risks and ethical issues. For example, when using gene therapy, unexpected side effects are possible, and the use of AI and machine learning can lead to problems with the confidentiality of patient data. In general, the use of innovative methods and technologies can significantly improve the effectiveness of treatment of chronic diseases and improve the quality of life of patients. However, before the introduction of these methods and technologies into medical practice, it is necessary to conduct thorough research, evaluate the effectiveness and safety, as well as take into account ethical and legal aspects","PeriodicalId":41505,"journal":{"name":"Journal of Complementary Medicine Research","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75203432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}