2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings最新文献_第3页

An active micro-electrode array with spike detection and asynchronous readout 具有尖峰检测和异步读出的有源微电极阵列

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981794

T. Datta, Bathiya Senevirathna, Alexander Castro, E. Smela, P. Abshire

{"title":"An active micro-electrode array with spike detection and asynchronous readout","authors":"T. Datta, Bathiya Senevirathna, Alexander Castro, E. Smela, P. Abshire","doi":"10.1109/BioCAS.2014.6981794","DOIUrl":"https://doi.org/10.1109/BioCAS.2014.6981794","url":null,"abstract":"We present an active micro-electrode array for neural recording with integrated spike detection and an asynchronous readout architecture. Neural amplifier arrays generate voluminous data because of the necessary per-channel sampling rates and number of channels in a dense array. Most of the time, neural cells produce well below 100 spikes per second, with action potential durations generally on the order of 1 ms, and accordingly much of the recorded data from a neural amplifier is not of interest. In the case of dense arrays recording from single units, only the timing of action potentials is relevant and spike sorting is not required. In such a case, the bandwidth requirement of the neural array can be reduced by employing an event-driven data communication protocol such as address event representation (AER). In our array, these events are generated by the spike detection circuits and then relayed to AER modules that send the address of the spiking neuron off-chip using a digital encoding scheme. Based on simulation data, the system implemented here reduces bandwidth requirements by a factor of 1600 in comparison to traditional synchronous sampling.","PeriodicalId":414575,"journal":{"name":"2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127867778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Live demonstration: Characterization of a wireless implantable infusion micropump for small animal research under simulated in vivo conditions 现场演示:在模拟体内条件下用于小动物研究的无线植入式输液微泵的特性

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981685

Angelica M. Cobo, Heidi Tu, R. Sheybani, E. Meng

引用次数: 1

Live demonstration: A CMOS sensor platform with 1.2 µm × 2.05 µm electroless-plated 1024 × 1024 microelectrode array for high-sensitivity rapid direct bacteria counting 现场演示:具有1.2µm × 2.05µm化学镀1024 × 1024微电极阵列的CMOS传感器平台，用于高灵敏度快速直接细菌计数

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981688

S. Ota, K. Niitsu, H. Kondo, M. Hori, K. Nakazato

{"title":"Live demonstration: A CMOS sensor platform with 1.2 µm × 2.05 µm electroless-plated 1024 × 1024 microelectrode array for high-sensitivity rapid direct bacteria counting","authors":"S. Ota, K. Niitsu, H. Kondo, M. Hori, K. Nakazato","doi":"10.1109/BioCAS.2014.6981688","DOIUrl":"https://doi.org/10.1109/BioCAS.2014.6981688","url":null,"abstract":"High-sensitivity rapid direct bacteria counting is an essential key method for point-of-care testing. Counting pathogens (cells, viruses, and bacteria) directly in real time with high sensitivity is useful in maintaining human health and preventing pandemics or bioterrorism. However, conventional counting methods with high sensitivity such as the polymerase chain reaction and cultivation-based biochemical testing are time consuming and require controlled places and well-trained staff. On the other hand, conventional rapid approaches such as immuno-chromatography and ATP bioluminescence schemes are insufficient with respect to sensitivity. As an alternative, electro-chemical sensing approaches using a microelectrode have been intensely investigated because of its high-sensitivity, simplicity, and high-throughput. In this work, a CMOS sensor platform with a bacteria-sized (1.2 μm × 2.05 μm) Au electroless-plated 1024 × 1024 microelectrode array for high-sensitivity rapid direct bacteria counting is demonstrated. For high-sensitivity direct pathogen counting, Au microelectrodes are required to be as small as the target cell. By improving a self-aligned electroless plating technique, the size of microelectrodes on a CMOS sensor chip was successfully reduced to 1.2 μm × 2.05 μm, corresponding to 1/20th of the smallest size reported in literature. Two test chips with 1024 × 1024 and 32 × 32 sensor arrays were fabricated in a 0.6-μm CMOS process and microelectrodes were formed on them using electroless plating. In this demonstration, 2D counting used 32 × 32 sensor arrays with silicone (fig. 1) by CV is introduced.","PeriodicalId":414575,"journal":{"name":"2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115622108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

In vivo monitoring of blood-brain barrier leakage by using photoacoustic microscopy 光声显微镜在体内监测血脑屏障渗漏

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981653

Weitao Li, Lidong Xing, Ling Tao, Z. Qian, Liming Nie

引用次数: 0

General expression based inner loop unrolling scheme for TV-GD algorithm adopted in photoacoustic imaging 基于通用表达式的TV-GD光声成像内环展开方案

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981662

Jiasen Huang, Junyan Ren, Jun Xu, Yuanyuan Wang

引用次数: 0

A new microcontroller-based system to optimize the digital conversion of signals originating from load cells built-in into pedals 一种新的基于微控制器的系统，用于优化从内置到踏板的称重传感器发出的信号的数字转换

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981722

A. Proto, Daniele Bibbo, S. Conforto, M. Schmid

引用次数: 9

Energy harvesting system for wireless body sensor nodes 无线身体传感器节点能量收集系统

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981751

A. Liberale, E. Dallago, A. L. Barnabei

引用次数: 20

An implantable green fluorescence imaging device using absorption filters with high excitation light rejection ratio 一种植入式绿色荧光成像装置，采用高激发光抑制比的吸收滤光片

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981709

Yoshinori Sunaga, M. Haruta, Takahiro Yamaguchi, Mayumi Motoyama, Yasumi Ohta, H. Takehara, T. Noda, K. Sasagawa, T. Tokuda, J. Ohta

引用次数: 4

On-line Local Mean Decomposition and its application to ECG signal denoising 在线局部均值分解及其在心电信号去噪中的应用

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981634

Hsea-Ching Hsueh, Shao-Yi Chien

引用次数: 3

Cortical discrimination of natural vibration stimulation in rats for a BMI task 大鼠BMI任务中自然振动刺激的皮层辨别

2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981799

Yan Cao, Fang Wang, Qiaosheng Zhang, Kedi Xu, Yiwen Wang, Xiaoxiang Zheng

引用次数: 0