RAS Microbiology and Infectious Diseases最新文献_第2页

Moving ahead in HCV diagnostics: Need for the introduction of HCV core antigen assay in low and middle-income countries 丙型肝炎病毒诊断的进展:需要在低收入和中等收入国家引入丙型肝炎病毒核心抗原测定

RAS Microbiology and Infectious Diseases Pub Date : 1900-01-01 DOI: 10.51520/2766-838x-8

E. Gupta, Akshita Gupta, PadakiNagaraja Rao, Srinivas Chakravarthy Narsimhachar, A. Arora, J. Sickan, Ajay Darbar, Hussain Ali

{"title":"Moving ahead in HCV diagnostics: Need for the introduction of HCV core antigen assay in low and middle-income countries","authors":"E. Gupta, Akshita Gupta, PadakiNagaraja Rao, Srinivas Chakravarthy Narsimhachar, A. Arora, J. Sickan, Ajay Darbar, Hussain Ali","doi":"10.51520/2766-838x-8","DOIUrl":"https://doi.org/10.51520/2766-838x-8","url":null,"abstract":"Hepatitis C virus (HCV) infections are associated with significant morbidity and mortality globally. The diagnosis of HCV is primarily based on indirect serological assays such as enzyme-linked immunosorbent assay (ELISA), chemiluminescence immunoassay (CIA), and rapid diagnostic tests to detect HCV antibodies. Direct tests detect/quantify components of HCV virions, such as HCV ribonucleic acid (RNA) (nucleic acid test or nucleic acid amplification test [NAT]) and HCV core antigen (HCVcAg). The HCVcAg assay (CIA, Abbott ARCHITECT) is an immune assay used for the quantitative determination of the HCVcAg. This test is simple and fast with the potential to be incorporated into diagnostic guidelines and be used in combination with anti-HCV (CIA) as an effective screening test. HCVcAg can also be used as a potential biomarker for treatment initiation and monitoring patients to assess the treatment response. Apart from this, the scope for implementation of the HCVcAg assay in resource limited setting lies in screening of immune compromised patients where anti-HCV serology is not dependable. However, concerns related to lower sensitivity compared to HCV RNA do exist. Nevertheless, the HCVcAg assay can make a significant difference in the measures taken for the control and eradication of hepatitis C and its complications in India.","PeriodicalId":409797,"journal":{"name":"RAS Microbiology and Infectious Diseases","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130693083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Lactic Acid Bacteria Isolated from Local Commercial Yahe (Fermented Caridean-Shrimp) Products 地方商业产虾发酵产品中乳酸菌的鉴定

RAS Microbiology and Infectious Diseases Pub Date : 1900-01-01 DOI: 10.51520/2766-838x-11

Say Sophakphokea, Rith Sokuncharya, Norng Chakriya, Ang Vichheka, Chheun Malyheng, Ly Sokheng, Prom Kimheang, C. Rithy, C. Chim

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引用次数: 0

Time scale of the growth progress in bacterial cultures: a self-consistent choice 细菌培养物生长过程的时间尺度:一个自洽的选择

RAS Microbiology and Infectious Diseases Pub Date : 1900-01-01 DOI: 10.51520/2766-838x-12

A. Schiraldi, R. Foschino

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引用次数: 2

ATPase Effects on pro-nutrients-mTOR release long fatty acids chains which under mitochondrial phospholipase, synthase & synthetase effects form three ROR-alpha, beta, gamma isoform atp酶对营养原的作用- mtor释放长脂肪酸链，在线粒体磷脂酶、合成酶和合成酶的作用下形成3种ror - α、β、γ亚型

RAS Microbiology and Infectious Diseases Pub Date : 1900-01-01 DOI: 10.51520/2766-838x-7

A. Tantawi

引用次数: 0