Saudi Journal of Pathology and Microbiology最新文献_第4页

Genetic Susceptibility to Severe Forms of COVID-19: What we learned in 2022 对COVID-19严重形式的遗传易感性:我们在2022年学到的东西

Saudi Journal of Pathology and Microbiology Pub Date : 2023-04-26 DOI: 10.36348/sjpm.2023.v08i04.005

R. Benmansour, M. R. Tagajdid, S. Elkochri, R. Aabi, H. Elannaz, A. Laraqui, B. Mchichi, N. Touil, K. Ennibi, I. L. Amine

引用次数: 1

A Rare Case of Extensive Chromoblastomycosis 罕见的广泛性嗜铬菌病1例

Saudi Journal of Pathology and Microbiology Pub Date : 2023-04-17 DOI: 10.36348/sjpm.2023.v08i04.004

T. Teja, L. Krishna, N. Kumari, C. Swathi

引用次数: 0

A Study on Surgical Site Infection, their Bacteriological Profile and Antimicrobial Susceptibility Pattern in Tertiary Care Hospital, Rajkot, Gujrat 古吉拉特邦拉杰科特三级医院手术部位感染及其细菌学特征和抗菌药物敏感性研究

Saudi Journal of Pathology and Microbiology Pub Date : 2023-04-15 DOI: 10.36348/sjpm.2023.v08i04.002

Nidhi S Patel, Aucharina D Sangma, Madhulika Mistry

{"title":"A Study on Surgical Site Infection, their Bacteriological Profile and Antimicrobial Susceptibility Pattern in Tertiary Care Hospital, Rajkot, Gujrat","authors":"Nidhi S Patel, Aucharina D Sangma, Madhulika Mistry","doi":"10.36348/sjpm.2023.v08i04.002","DOIUrl":"https://doi.org/10.36348/sjpm.2023.v08i04.002","url":null,"abstract":"Introduction: Surgical site infection is defined as infection occurring within 30 days after surgical operation and affecting either incision or deep tissues at the operation site. SSIs cause substantial morbidity and mortality. This study was aimed at obtaining the incidence of SSI and to evaluate the risk factors as well as to formulate an antibiotic policy. Aims and Objectives: To determine the incidence, risk factors and the bacteriological profile for SSI and their antimicrobial susceptibility patterns at PDUMC, Rajkot. Materials & Method: Total of 872 pus samples from surgical ward were studied from January 2022 to June 2022. The isolates were identified by colony morphology, Gram’s stain and conventional biochemical reactions. Antibiotic sensitivity testing was done by Kirby-Bauer disc diffusion method as per CLSI guidelines 2021. Results: Total 272 microbial pathogens were isolated. Out of these, 28(10.29%) were Gram- positive Cocci, 244(89.70%) were Gram-negative Bacilli whereas 64 showed polymicrobial growth. Out of total Gram negative isolates, 108(44.26%) showed Klebsiella species followed by Pesudomonas aeruginosa 72(26.50%). Out of total Gram positive isolates, Staphylococcus aureus 16(57.14%) is the predominant pathogen followed by Coagulase Negative Staphylococci 12(42.85 %). Conclusion: The study gives an insight into bacterial pathogens and their antibiotic sensitivity patterns isolated from surgical site infections. Surveillance of SSI helps in early detection, appropriate use of antibiotics & to reduce the rate of SSI.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133184279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case Report of an Extra Pulmonary Tuberculosis: Testicular Tuberculosis 罕见外肺结核一例:睾丸结核

Saudi Journal of Pathology and Microbiology Pub Date : 2023-04-15 DOI: 10.36348/sjpm.2023.v08i04.003

Shivangi Goswami, Riya Chudasama, G. Kavathia

引用次数: 0

“Look Both Ways When You Cross the Street” – A Reporting Sine Qua Non “过马路时要看两边”——报告的必要条件

Saudi Journal of Pathology and Microbiology Pub Date : 2023-04-04 DOI: 10.36348/sjpm.2023.v08i04.001

引用次数: 0

Multiresistant Bacteria in Neonatal Intensive Care and the Contribution of Molecular Biology 新生儿重症监护中的多重耐药细菌及其分子生物学的贡献

Saudi Journal of Pathology and Microbiology Pub Date : 2023-03-30 DOI: 10.36348/sjpm.2023.v08i03.006

H. Aamri, F. Bennaoui, N. Slitine, N. Soraa, F. Maoulainine

{"title":"Multiresistant Bacteria in Neonatal Intensive Care and the Contribution of Molecular Biology","authors":"H. Aamri, F. Bennaoui, N. Slitine, N. Soraa, F. Maoulainine","doi":"10.36348/sjpm.2023.v08i03.006","DOIUrl":"https://doi.org/10.36348/sjpm.2023.v08i03.006","url":null,"abstract":"Epigenetics is a very active field of research today. This is a mechanism by which environmental factors can influence gene expression. Indeed, epigenetics has been defined as a new science aimed at studying the mechanisms by which the genotype generates the phenotype, without there being any modifications in the DNA sequence. In this context, we conducted a prospective study on the records of 523 patients hospitalized in the neonatal intensive care unit of the CHU Mohamed VI in Marrakech, over a period of 6 months, from July 01, 2019 to December 31, 2019. Main results obtained were as follows: A high MRB carriage rate affecting 45.5% of hospitalized patients during the study period. Late MRB infections are an important part of this. The analysis of the risk factors of these infections had demonstrated the major role of invasive procedures, in particular mechanical ventilation and KTVO, as well as the high duration of hospitalization which was on average 17.47 days in our study. The bacteriological profile was dominated by enterobacteriaceae, particularly K. pneumoniae and E. cloacae. Of all the MRBs sent to the Kremlin Bicêtre hospital, 55 strains were analyzed by MLST; including 36 strains of K. pneumonia and 19 strains of E. cloacae. The Enterobacteriaceae strains analyzed in our study were mainly carbapenemase producers, of the NDM and OXA-48 type, and ESBL type CTX-15M. Of all the bacterial clones identified, a high rate of resistance to antibiotics, in particular carbapenems, was noted in the following clones: ST 1805, ST 1158 and ST 307. The ST 1805 clone was exclusively found in our series.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132398186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Basaloid Squamous Cell Carcinoma of Cervix – A Rare Case Report 子宫颈基底样鳞状细胞癌1例报告

Saudi Journal of Pathology and Microbiology Pub Date : 2023-03-25 DOI: 10.36348/sjpm.2023.v08i03.005

Sayiri Sravani, L. Krishna, S. Srikanth, M. Jyothi, D. P

引用次数: 0

Cutaneous Rhinosporidiosis Masquerading as a Soft Tissue Tumour Diagnosed on FNAC 皮肤鼻孢子虫病伪装成软组织肿瘤的FNAC诊断

Saudi Journal of Pathology and Microbiology Pub Date : 2023-03-04 DOI: 10.36348/sjpm.2023.v08i03.004

Rini Rachel Philip, Jayalakshmy, P. L, S. S

引用次数: 0

Neutrophil to Lymphocyte Ratio as a Denotative of Type II Diabetes Mellitus 中性粒细胞与淋巴细胞比值作为II型糖尿病的标志

Saudi Journal of Pathology and Microbiology Pub Date : 2023-03-04 DOI: 10.36348/sjpm.2023.v08i03.003

Vaishnavi Selvaraju, R. Dharshini, J. Jayaganesh, Munazza Kaif,B. K

{"title":"Neutrophil to Lymphocyte Ratio as a Denotative of Type II Diabetes Mellitus","authors":"Vaishnavi Selvaraju, R. Dharshini, J. Jayaganesh, Munazza Kaif,B. K","doi":"10.36348/sjpm.2023.v08i03.003","DOIUrl":"https://doi.org/10.36348/sjpm.2023.v08i03.003","url":null,"abstract":"Introduction: The neutrophil-lymphocyte ratio (NLR) is an economically accessible tool useful in cases of Type II Diabetes Mellitus (T2DM). It can be utilized as a laboratory index, indicating systemic inflammation. The sensitivity of NLR to HbA1c must be validated to utilize for its prognostic potential. Correlation of HbA1c with NLR and other parameters have been analyzed to assess the utility of NLR in chronic cases of T2DM, thereby evaluating the utility of NLR as a marker of systemic inflammation in diabetes. Place and Duration of study: Department of Pathology, Saveetha Medical College, Chennai, One year. Objectives: 1. To compare levels of NLR and other parameters in diabetics with those of healthy people and observe the nature of correlation between HbA1c and other parameters.2. To find the linear relationship between HbA1c and other parameters in the diabetic population. Material and methods: An observational study conducted at our Institute from January to October 2020. Blood profiles of 240 T2DM patients and 100 healthy controls were recorded. Results: The NLR (5.35) of T2DM group was significantly elevated (p 0.001) compared to NLR of control group (2.16). Urea and creatinine levels had positive regression coefficients with HbA1c indicating susceptibility of diabetic patients to diabetic nephropathy. Conclusion: NLR showed significance in T2DM. Increased NLR is associated with elevated HbA1c and poor glycemic control in patients with T2DM. It can be used as a prognostic tool during the follow up of diabetic patients.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126140053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platelet Indices in Differentiating Reactive Versus Clonal Thrombocytosis 鉴别反应性血小板增多症与克隆性血小板增多症的血小板指标

Saudi Journal of Pathology and Microbiology Pub Date : 2023-03-04 DOI: 10.36348/sjpm.2023.v08i03.002

Vaishnavi Selvaraju, J. Jayaganesh, Nikshayaa Nikshayaa

{"title":"Platelet Indices in Differentiating Reactive Versus Clonal Thrombocytosis","authors":"Vaishnavi Selvaraju, J. Jayaganesh, Nikshayaa Nikshayaa","doi":"10.36348/sjpm.2023.v08i03.002","DOIUrl":"https://doi.org/10.36348/sjpm.2023.v08i03.002","url":null,"abstract":"Aim: To evaluate the platelet indices in differentiating reactive and clonal thrombocytosis. Study Design: Observational study Place and Duration of Study: Department of Pathology, Saveetha Medical College, Chennai, and the duration of study is one year. Methods: This is an observational study conducted at our college for a one-year duration. A total of 100 patients with thrombocytosis of platelet count over 4.5 lakhs/mm3 will be included in the study. The study sample consists of cases with thrombocytosis of over 4.5 lakhs. The utility of platelet indices Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) for the differential diagnosis of thrombocytosis were analysed and assessed. Results: Out of the total 100 cases, 94 were reactive thrombocytosis, and 6 were confirmed to be clonal in origin. Infectious and reactive aetiology was significantly more compared to clonal thrombocytosis. Patients with reactive thrombocytosis showed a lower mean platelet volume and platelet distribution width compared to primary thrombocytosis. In reactive thrombocytosis, MPV ranged from 8.0 - 9.0 fl with mean MPV of 10.6 fl and PDW ranged from 8.4 – 10.1 % with mean PDW of 10.26 %. In clonal thrombocytosis, MPV ranged from 8.2 –1 1.1 fl with mean MPV of 9.5 fl and PDW range was 8.9 – 11.2 % with mean PDW of 10∙1%. Conclusions: The findings of our study favour a reactive cause in thrombocytosis when MPV and PDW are in the lower range and clonal causes had a high MPV and PDW in comparison to reactive causes.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132995304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0