Saudi Journal of Pathology and Microbiology最新文献

{"title":"Surinfection of the Renal Graft by a Strain of Klebsiella pneumonia Oxa 48 Producer and Therapeutic Impasse","authors":"H. Saffour, S. Rouhi, L. Darfaoui, A. Lamrani, N. Soraa","doi":"10.36348/sjpm.2022.v07i05.001","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.001","url":null,"abstract":"The surinfection of the renal graft by multi-resistant germs constitutes a serious complication, which can engage the functional and vital prognosis in renal transplant patients. It is responsible for a problem of therapeutic management and of the benefit/risk ratio between antibiotic therapy at therapeutic doses and the contraindications linked to renal insufficiency and therapeutic impasse. This work reports the case of a kidney transplant recipient who died following complications of a superinfection of the graft by a strain of Klebsiella pneumoniae producing OXA 48. The purpose of this observation is to underline the nosocomial risk in kidney transplant patients and the difficulty of the therapeutic management of these multi-resistant infections.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133509379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross Sectional Study of Clinical and Histopathological Spectrum of Pediatric Brain Tumours","authors":"S. Gandhi, A. Meena, Anita Harsh, S. Choudhary, S. K. Meena, Sonu Dhayal","doi":"10.36348/sjpm.2022.v07i04.006","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i04.006","url":null,"abstract":"Introduction: Brain tumors are the most common tumor of the childhood and the second most common malignancies after haematological malignancies. Childhood central nervous system (CNS) tumors differ significantly from adult brain tumors in reference to their sites of origin, clinical presentation, tendency to disseminate early, histological features and their biological behaviour. Aims and Objective: Analyse the Clinical and histopathological spectrum of brain tumors, in pediatric patients ≤18 year of age. Materials and Method: This was a cross sectional study conducted at the department of pathology, SMS medical college, Jaipur from January 2020 to October 2021. This is a laboratory based descriptive type of observational study and data of brain tumors in children equal or less than 18 year of age procured and their clinico-histopathological spectrum were analyszed. Result: In our study, Out of 116 patients 51.8 % were male and 48.2 % were female. Mean age for the male cases were 10.11 and for female cases were 9.78. we observed intracranial pediatric tumors 67 cases (57.7%) were located in infratentorial region and 49 cases (43.3%) were located in supratentorial region and incidence for intracranial tumor was 39(33.62%) cases of astrocytomas followed by 25 (21.55%)cases of medulloblastoma, 20 (17.24%)cases of ependymoma, 13 (11.20%) cases of craniopharyngioma, 5 (4.31%) cases of pituitary adenoma, 4 (3.44%) cases of meningioma, 3 (2.58%) cases of embryonal and choroid plexus tumor, 2 (1.72%) cases of ganglioglioma and 1 (0.86%) case of Schwannoma and PNET. In this article, Based on tumor location, the symptoms of CNS tumors on the supratentorial region were headache (22 cases, 44.8%), impaired vision (10 cases, 20.4%), seizures (6 cases, 12.2%), vomiting (4 cases, 8.1%). Symptoms of CNS tumors on the infratentorial region were headache (48 cases, 71.6%), vomiting (5 cases, 7.4%), impaired vision (4 cases, 5.9%), seizures (3 cases, 4.4%). Conclusion: Infratentorial cases, maximum number of cases were medulloblastomas and supratentorial cases, maximum number of cases were astrocytic tumours. Overall astrocytic tumours in all senses constituted the most common group of CNS tumours. Within astrocytoma, low grade astrocytoma (grade I & II) was most common CNS paediatric tumour.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129271104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal Septicemia: Clinical and Epidemiological Features","authors":"Rouhi S, Fmr Maouainine, S. N., Slitine N, Bennaoui F, Lamrani Hanchi A, Nachate S","doi":"10.36348/sjpm.2022.v07i04.005","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i04.005","url":null,"abstract":"Introduction: to compare the clinical, biological, and evolutionary profiles of sepsis with multi-drug resistant and non-multi-drug resistant bacteria in the newborn population. Methods: we performed a prospective, observational, comparative study to monitor all the episodes of blood stream infection, received from the neonatal intensive care, from June to December 2019. Collected data included demographics, symptoms at the time of sepsis, laboratory values, microbiologic results, preliminary and final outcomes. Results: Out of 219 positive blood cultures, 93 episodes were retained. The median age was 6,66 days, 63.4% of newborns were male and 62,4% were premature, 39% of whom had a gestational age of less than 34 weeks. Multidrug-resistant (MDR) bacteria caused 68 sepsis episodes, while non-MDR resistant bacteria caused 25. Bacteremia with MDR organisms, in comparison with non-MDR organisms was associated with poorer preliminary outcomes after empirical antibiotherapy (14% vs 32%; P= 0,001), higher overall mortality rate (20% vs. 51%, P =0.003), and longer antibiotic intake (9.84 vs 7.56 ; P=0,02). The major risk factor found is prematurity (70% vs 40%, P<0,001), No statistical significance was found when other clinical features or laboratory values were compared for infections with MDR vs. non-MDR bacteria. Conclusion: Septicemia with MDR bacteria is more common than non-MDR one in NICU, and it is related to higher morbidity and mortality rates.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131157743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Ovarian Lymphoma in Late Pregnancy: A Case Report","authors":"Dr. Amna Moulana, Dr. Mohamed El Tahmoudy, Dr. Riyazuddin Ansari, Dr. Bushra Ahmed shaikh, Dr. Arjumand Moulana","doi":"10.36348/sjpm.2022.v07i04.004","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i04.004","url":null,"abstract":"Involvement of the ovary with malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian Burkitt lymphoma is very rare and mainly affects young children. We present a case of a 25-year old woman at 37 weeks pregnant with sporadic Burkitt lymphoma who presented as having ovarian cancer. The patient was managed via elective cesarean section and unilateral oophorectomy. Histopathological examination and immunohistochemical stains were carried out, revealing non-Hodgkin B-cell Burkitt lymphoma. After the diagnosis, the patient was referred to the oncology center for chemotherapy.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126271697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myxoinflammatory Fibroblastic Sarcoma: New Case Report of a Rare Entity","authors":"M. Allaoui, A. Kessab, M. Azzakhmam, Mohamed Amine Es- Saoudi, M. Ochi, A. Ktaibi, H. E. Agouri, A. Damiri, H. Chahdi, M. Oukabli","doi":"10.36348/sjpm.2022.v07i04.003","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i04.003","url":null,"abstract":"Myxoinflammatory fibroblastic sarcoma (MIFS) is a malignant mesenchymal tumor most commonly occurring in the distal extremities of adults, it generally behaves like a low-grade tumor but is still able to progress locally and metastasize to distant sites, rarely resulting in death. It is a tumor whose unusual morphology can lead to misdiagnosis, either in the non-neoplastic sense (infectious or inflammatory) or as another sometimes malignant tumor entity. The genetic abnormalities detected in MIFS are the t(1;10)(p22:q24) translocation, with rearrangements of TGFBR3 and MGEA5 genes associated with increased levels of FGF8, with chromosome 3 marker/ring formation, and amplification of the VGLL3 locus.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125244156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey of Acne Vulgaris in Selective Districts of Punjab, Pakistan","authors":"A. Javed, M. Shahid, Mehrunisa Hassan, Wajeeha Faiz, Sahar Tariq, B. Ahmad, Sufyan Saleem","doi":"10.36348/sjpm.2022.v07i04.001","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i04.001","url":null,"abstract":"Acne vulgaris is a common dermal ailment which is reported globally. Currently, a cross sectional survey (manual and online) in selective districts of Punjab region was conducted and it was concluded that disturbance in sebum production and frequent blockage of skin pores occur due to different potent factors which include improper dietary habits, side effects of medication, genetic complications, environmental conditions and lack of awareness of personal hygiene. Thus the future research efforts should be channelized to ensure provision of low coat and side effects free local pharmacognosal products for acne treatment along with its programmed general public awareness.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"240 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115159536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation of Acinetobacter Species from Wound Infection and Their Antimicrobial Resistance Pattern in a Tertiary Care Hospital in Rajshahi, Bangladesh","authors":"S. Nath, Md Mizanur Rahman","doi":"10.36348/sjpm.2022.v07i03.015","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i03.015","url":null,"abstract":"Background: Acinetobacter species has emerged as an important pathogen globally in various infections especially in hospital acquired infections. Objectives: This study was conducted to determine the antibiotic resistance pattern of Acinetobacter species from wound swab samples. Materials and Methods: A Cross sectional study was undertaken in Department of Microbiology, Rajshahi Medical College (RMC), Rajshahi, Bangladesh from period January 2014 to December 2014. A total 13 Acinetobacter were collected from 292 wound infection patients of surgery word and its allied brances in Rajshahi medical college hospital (RMCH). Isolation, Identification and sensitivity of Acinetobacter species were performed by manual method. Results: Out of 292 patients 13(4.4%) patients showed growth of Acinetobacter species. Resistance observed to Meropenem was 38.46%, Piperacillin -Tazobactum 61.53%, Amikacin 53.84%, Ceftazidime 76.92%, Gentamicin 61.53% and Levoflaxacin 67.23%. This data suggest that Acinetobacter isolated from hospital exhibits resistanace to multiple antimicrobial drugs. Conclusion: The study will help to implement better infection control strategies and improve the knowledge of antibiotic resistance patterns of Acinetobacter species in our region.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124014453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paraneoplastic Dermatomyositis Revealing Tardly an Ovarien Cancer at Metastatic Stage who Responded Favorably to Treatment","authors":"I. Hallab, Y. Zemmez, Hicham Titou, O. Boudi, R. Frikh, N. Hjira, M. Boui","doi":"10.36348/sjpm.2022.v07i03.014","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i03.014","url":null,"abstract":"Dermatomyositis is a type of inflammatory myopathy characterized by inflammatory and degenerative changes of the muscles and skin. The paraneoplastic dermatomyositis is a subtype associated with cancer. The pathophysiothogy remains unfully understood. The diagnosis is supported by both the clinical and serological features. The treatment involves both the DM and the malignancy. Multi-disciplinary management is fundamental for patients. However the pronosis remains usually poor. We report a case of paraneoplastic dermatomyositis revealing an ovarian cancer, the purpose is to illustrate the diagnostic, therapeutic and pronostic of this entity.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122722304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Squamous Cell Carcinoma on Permanent Tattoo of the Face: Diagnostic that should be Prevent by Demoscopic Monitoring and Topical Chemotherpy","authors":"I. Hallab, A. Kinany, Y. Zemmez, Hicham Titou, O. Boudi, R. Frikh, N. Hjira, M. Boui","doi":"10.36348/sjpm.2022.v07i03.013","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i03.013","url":null,"abstract":"Many skin lesions have been reported in connection with tattoos, both benign and malignant. The pathogenesis of malignant transformation in tattoos is unknown, although hypotheses include the toxic effects of the pigments. To date, we have notice 31 case reports and series (17 men, median age: 50.5 years) of KA and CSC on tattoos. Other factors; UV exposure, fair skin, and immunosuppression increase incidence of cSCC. Recurrence and metastasis are associated with tumor diameter greater than 2 cm, depth greater than 2 mm or beyond subcutaneous fat, extensive or large-caliber perineural involvement, and poor differentiation on histopathology. AJCC 8 is used for TNM staging for cSCC of the head and neck. BWH offers an alternative T staging system. Management is primarily surgical with rare indications for adjuvant chemoradiation.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124426146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomy and physiology features of developing cervical spine and zoological cultures as promoting of the new varieties of fishes","authors":"Huzaifa Saleem, Muhammad Tahir, Muhammad Adnan, Muhammad Sarfraz, Laraib Rida Malghani, F. Niazi, M. Izhar","doi":"10.36348/sjpm.2022.v07i03.012","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i03.012","url":null,"abstract":"Cellular cultures can be used to investigate the role of ciliates in forming of flocs of fishes in the absence of many other microbes. Aquaculture is rapidly expanding and faces numerous difficulties in achieving growing demands while maintaining the security and suitability of fish products. The primary motivation for developing fish cellular cultures, as till recent times, the most common application of these cultures, has been the exclusion and description of fish viruses which are the causal factors of epizootics in economically valuable aquaculture or fishery. Acinetobacter, Vibrio, and Pseudomonas grow faster in flesh media than in artificial media. Fish-protein-hydrolysate peptones have no interaction with prions which cause bovine spongiform encephalopathy. Tissue engineering can all be combined with advanced aquaculture technologies to make marine cellular cultures as an appealing option for producing in vitro fish meat. Fish waste products could be an interesting perspective of cost effective and efficient peptones, the use of which has resulted in good growth yields for a wide range of bacterial genera. Food loss starts immediately as the fish killed, so handling should be completed as soon as possible to avoid the development of bacteria and molds on it.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"265 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123968668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}