Saudi Journal of Pathology and Microbiology最新文献

{"title":"The Diagnostic Usefulness of Stool Antigen Test with Serum Helicobacter pylori Antibody and CLO Test in the Diagnosis of Helicobacter pylori Infection in Dyspeptic Patients","authors":"Santona Das Kanungo, S. A. Safwath, M. A. Nabi, Suborna Dey, Nargis Akhter Choudhury, Md. Ubaidul Islam","doi":"10.36348/sjpm.2022.v07i06.004","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i06.004","url":null,"abstract":"Introduction: Helicobacter pylori colonization of the human gastric mucosa potentially leads to chronic gastritis that may progress to peptic ulcer disease. Additionally, this micro-organism has been identified as a risk factor for the development of gastric carcinoma and gastric lymphoma. Its relation with non-ulcer dyspepsia has not been clear. Objective: To assess the diagnostic usefulness of stool antigen test with serum Helicobacter pylori antibody and CLO test in the diagnosis of Helicobacter pylori infection in dyspeptic patients. Materials and Methods: This was a cross sectional study was conducted in the Department of Microbiology, Sylhet M.A.G. Osmani Medical College in collaboration with the Department of Gastroenterology Sylhet M.A.G. Osmani Medical College, Sylhet from July 2012 to June 2013. The calculated sample size was 196 but in this study we took 150 patients due to financial constrain and time limitation. Patients upper GI tract for dyspepsia and whoever fulfilled the inclusion and exclusion criteria were considered as study sample. All the findings, previous history and reports of investigations were recorded in a preformed data collection sheet prepared for this purpose. The patient with clinical features suggestive of dyspepsia was selected for upper GI endoscopy. Results: For this purpose, 150 dyspeptic patients fulfilling the inclusion and exclusion criteria were enrolled. The age of the patients ranged from 18 to 80 years with the mean age of 43.35 (SD ± 16.30) years. There were 32 (21.3%) patients in the age group of 21 to 30 years, 31 (20.7%) patients in the age group of 31 to 40 years, 30 (20.0%) patients in the age group of 41-50 years, 26 (17.3%) patients in the age group of 51-60 years, 21 (14.0%) patients in the age group of above 60 years and 10 (6.7%) patients in the age group up to 20 years. There were 93 (62.0%) male and 57 (38.0%) female with a ratio of male to female was 163:1. Showed the distribution of patients according to endoscopic findings. Endoscopic findings was normal in 85 (56.7%) patients, duodenal ulcer in 26 (17.3%) patients, gastritis in 23 (15.3%) patients, and gastric ulcer in 16 (10.7%) patients. The distribution of patients according to CLO test. CLO test was positive in 97 (64.7%) patients and negative in 53 (35.3%) patients. The patients according to serum Helicobacter pylori antibody by ELISA. Serum Helicobacter pylori antibody was positive in 101 (67.3%) patients and negative in 49 (32.7%) patients. Stool antigen test was positive in 73 (48.7%) patients and negative in 77 (51.3%) patients. Using CLO test as the gold standard the sensitivity and specificity of stool antigen test in the diagnosis of Helicobacter pylori infection was 72.7% and 94.3% respectively. Positive and negative predictive values were 95.9% and 64.9% respectively. The overall accuracy was 80.0%. There was moderate agreement between the two test (Kappa, k=0.603; p<0.001). Using CLO test as the gold standard in the dia","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126174868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Urban North Indians Incidence of Dyslipidemia among Different Age Groups","authors":"Dr. Sharique Ahmad, Dr. Saba Naziya, Dr. Mohd Anwar, Tanish Baqar, Dr. Saeeda Wasim, Dr. Huma Parveen","doi":"10.36348/sjpm.2022.v07i06.003","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i06.003","url":null,"abstract":"Background: Coronary artery disease is a known entity of morbidity and mortality in industrialised countries. It is a major public health problem around the world. Coronary artery disease increase incidence in Indian population at least 10 years before in age than other ethnic groups. There are a numbers of factors associated with atherosclerosis the most important one is dyslipidemia. Recent studies suggest that over the span of 20 years, the total amount of triglycerides, cholesterol and Low Density Lipoproteins (LDL) `levels is usually increased in young urban populations. So, a study was performed out to know the prevalence of dyslipidemia in urban North Indians among different set of age groups. Methods: This is a descriptive cross-sectional study which was carried out on patients visiting to the blood collection centre of the Department of Pathology. Patients were divided into 3 groups with age 18 year to 40 year, 41 year to 60 year and >60 year by involving 1989 subjects of whom 532 were between 18 year to 40 year, 522 were between 41year to 60 year and 935 were > 60 year of age. This study included measurement of fasting serum lipid profile comprising of, Low Density Lipoprotein (LDL), High Density Lipoproteins (HDL), Triglycerides and total cholesterol. Results: Number of subjects studied, the prevalence of dyslipidemia was higher in <60 years age population. A remarkable difference in mean was observed statistically with the levels of triglycerides, LDL and total cholesterol of this age group ranging from 18- 40 years and for those who are >60 years. A remarkable difference for the levels of HDL was not found in age group between 18 – 40 years and > 40 years to 60 years. Mean cholesterol level was observed to be elevated between the age group 18 – 40 years. The mean peak triglycerides were observed in age group between 41-60 years. This elevated mean HDL levels were noticed in the age group who are > 60 years of age. Conclusions: Elevated percentage of dyslipidemia was observed in less than 60yrs age groups. Large population study is required to substantiate the results of this study. It is necessary to plan out comprehensive strategies for the screening and awareness in all ages on periodic basis.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122364336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Isolation, Identification & Antibiotic Susceptibility Pattern of Non-Fermenting Gram Negative Bacilli Isolated From Various Clinical Samples at Tertiary Care Hospital Rajkot, Gujarat, Western India","authors":"Dr. Suhani Gondha, Dr.G.U. Kavathia, Dr. Arpita Bhattacharya","doi":"10.36348/sjpm.2022.v07i06.002","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i06.002","url":null,"abstract":"Introduction: Nonfermenting gram-negative bacilli (NFGNB) are a taxonomically diverse group of aerobic, nonsporing, bacilli that either do not utilize glucose as a source of energy or utilize it oxidatively. They occur as saprophytes in the environment and some are also found as commensals in the human gut. In recent year NFGNB have emerged as important health care associated pathogens. They have been incriminated in infections such as bacteremia, meningitis, pneumonia, urinary tract infections, surgical site infections, wound infections, osteomyelitis etc. Materials and method: During Nine Month study period, various samples were collected aseptically and transported immediately to the bacteriology laboratory. The pathogens were identified by standard laboratory procedures including Gram’s staining, motility, culture, colony characters and biochemical reactions. Antimicrobial susceptibility testing was performed by modified Kirby Bauer method as per the CLSI guidelines using Muller-Hinton agar and available antibiotic disks. Result: A total number of 312 NFGNB were isolated from 4112 clinical samples. Most frequently isolates NFGNB were Pseudomonas aeruginosa (42.62%) and Acinetobacter spp. (25.32%). NFGNB isolates were more common in males (58.33%) as compared to females (41.67%). Maximum sensitivity was seen to Polymyxin B (100%), Meropenem (83.45) in Pseudomonas aeruginosa and Meropenem (78.48%), Pipracillin-tazobactum (62.02%) in Acinetobacter spp. Conclusion: NFGNB are emerging as important pathogens and shows resistance to commonly used antibiotics. Minimized use of available antimicrobial, regular use antimicrobial susceptibility surveillance and strict infection control measures are required to control this emerging antimicrobial resistance among NFGNB.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116886029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Development of Nutritive, Enhanced Bioactivities, Antioxidant, Antimicrobial, Antiparasitic, DNA Protection and New Insights","authors":"Amna Nadeem, Hafiz Muhammad Khubaib, A. Samee, Arsala Ali, S. Kamal, Nelofar Ansari, M. Rehman, Asifa Roohi, Muhammad Faraz Ali","doi":"10.36348/sjpm.2022.v07i06.001","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i06.001","url":null,"abstract":"Herbal remedies are widely utilized as therapeutic approaches for different medical conditions all over the globe. Various chemical herbicides and pesticides, including the organic and inorganic Sulphur compounds, benzimidazoles, imazalil, and oxidizing compounds, have just been proposed to handle the diseases in plants in recent years to achieve this goal. Anti-inflammatory, antihyperlipidemic, anticancer, and oxidative, analgesics, anorexiant, plasmid curing, and antihyperglycemic properties prominent in medicinal plants. The leaves of another medicinal plant , Dracocephalum moldavica have been used for the treatment of stomach and liver disorders, headaches and congestion. Different plants also exhibit the multiple action against variety of microbial pathogens. Baccharis trimera used against the infections caused by Staphylococcus aureus, Salmonella gallinarum and Escherichia coli, Bacillus cereus strains. Ascorbic acid (vitamin C), carotenoids, tocopherol (vitamin E), and plant phenolic compounds are examples of low-molecular-weight compounds, non-enzymatic anti - oxidants obtained from nutrition. Bilirubin, serotonin, lipoic acid, ketoacids, uric acid, sex hormones, coenzyme Q, and other low-molecular-mass antioxidant chemicals are produced in vivo.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132399324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Isolated Genital Psoriasis: Uncommon Location That Make the Diagnostic Difficult","authors":"H. I, O. Stitou, O. Boudi, R. Frikh, N. Hjira, M. Boui","doi":"10.36348/sjpm.2022.v07i05.007","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.007","url":null,"abstract":"There are many dermatoses that can affect the genital area. These may be isolated genital conditions or signs of a general cutaneous disorder. Genital dermatoses can be classified as physiologic variants, and inflammatory, neoplastic, or infectious in etiology. Psoriasis is a chronic autoimmune disease, which has a prevalence of about 3% with genital involvement, reported in 29% a 40% of patients. Although the diagnosis of genital psoriasis can be aided by the presence of classic psoriatic plaques on the body, the penis may be the only affected region. In uncertain cases, a skin biopsy can lead to diagnosis. Initial management should consist of mild topical corticosteroids with increasing potency titrated to effect or topical calcineurin inhibitors. Systemic therapy with disease modifying small molecules or biologic drugs may be considered when disease is particularly bothersome, widespread, or unresponsive to conservative approache. This article provides a broad overview for dermatologists in addressing the Psoriasis wich is placed on. Recommendations for diagnostic evaluation, treatment, and appropriate follow-up are discussed.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123107806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavior Changes toward Preventive Actions after Second Vaccination of Coronavirus -19 among Students University of Hail: Cross-Sectional Study","authors":"M. A. Bealy, Hisham Ali A Al Yateem, J. A. Alessa, A. M. A. A. Zain, E. Sogeir","doi":"10.36348/sjpm.2022.v07i05.006","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.006","url":null,"abstract":"Background: The severe respiratory syndrome coronavirus (COVID-19) pandemic has affected many aspects of life, much vaccine adopted to minimize morbidity and mortality due to COVID-19. Aim: To assess behavior changes after taken second dose of COVID-19 vaccine among students in university of Hail. Methodology: This cross-sectional questionnaire based study involved 350 participants from Hail University, Saudi Arabia. We distributed online questionnaire to determine differences in the protective measures before and after the second dose of COVID-19. Results: We included 350 participants from Hail University in Saudi Arabia in this study. Declines at different levels was detected in all protective measures after the second dose of COVID-19 vaccine that were in the questionnaire compared to before taking the second dose of COVID-19 vaccine. The significance of the behavior changes after receiving second dose of COVID-19 vaccine compared to behavior changes before receiving second dose of COVID-19 vaccine (P<0.0001). Conclusion: the second dose of vaccine resulted noticeable changes in preventive measurement behavior in university of Hail students.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114196998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet Refractory Cases after Transfusion of Fresh and Stored Platelet in all Children","authors":"Dr. Alamgir Ahmed, Dr. Mafruha Akhter, Dr. Mohammad Mizanur Rahman, Dr. Mohammad Ali, Dr. Md. Kamrul Hossain, Dr. Lokesh Chakraborty, Dr. S. M. Masud, Dr. Salma Sadiya, Dr. Rawshan Ara, Dr. Delara Sultana","doi":"10.36348/sjpm.2022.v07i05.005","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.005","url":null,"abstract":"Introduction: Acute leukemia is the most common form of cancer in children, platelet transfusion is needed for the chemotherapy of acute lymphoblastic leukaemia children. Platelets are transfused for therapeutic and prophylactic purposes. Transfusion of stored platelet concentrates (up to 5 days) has been demonstrated to be as effective as transfusion of fresh platelet concentrates (upto 24 hours). Platelet refractory cases were also observed in this study that was detected by Corrected Count Increment (CCI) and Percent Platelet Recovery (PPI) at 1hour and 24 hours. Aim of the study: The aim of this study was to observe the platelet refractory cases after transfusion of fresh and stored platelet in acute lymphoblastic leukemia (ALL) in a tertiary care hospital, Dhaka. Methods: A cross-sectional study was conducted in the Department of Clinical Pathology, Paediatric Haematolo- Oncology and transfusion Medicine BSMMU, Department of Haematology and Paediatric Haemato-Oncology in Dhaka Medical College Hospital from March 2010 to February 2011 where 81 children diagnosed with acute lymphoblastic leukaemia were taken as the study population. Non probability purposive sampling was used by fulfilling the inclusion criteria. Ethical consideration was taken by the BSMMU ethical review committee. A data sheet with two parts (Part A and Part B) was designed with a view to collect data from the patients to be enrolled in the study. Data were analyzed using the SPSS version 25.0. Results: Out of 81 in 47 children with acute lymphoblastic leukemia (ALL), fresh platelet concentrates (FPC) (upto 24 hours) or day-0 platelets were transfused. In 34 children, stored platelet concentrates (SPC) (days 1–5) were transfused. In 27 cases, platelet concentrates were transfused both fresh and stored. In FPC and SPC, the corrected count increment at one hour (CCI 1h) was 20.5×109/L and 18.9×109/L respectively. FPC and SPC values for the mean corrected count increment at 24 hours (CCI 24h) were 15.5×109/L and 13.8×109/L respectively. Platelet refractory cases were 15(18.5%) out of 81 cases transfused. Platelet refractory cases were 7(15%) out of 47 cases transfused with FPC and 8(23%) out of 34 cases transfused with stored platelet concentrate (SPC). There were no significant differences (P<0.05) between FPC and SPC according to platelet refractoriness. Conclusion: In vivo quality of freshly generated platelet (upto 24 hours) versus stored platelet concentrates (up to 5 days) were determined after 1 hour and 24 hours. 1-5 day’s stored PRP-PCs are as effective as fresh PRP-PCs for sufficient platelet increment.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128852027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dabska Tumor (Endovascular Papillary Angioendothelioma) of Orbit in a Middle Aged Male: A Case Report","authors":"Dr. Liz Maria Joseph, Dr. Sankar S","doi":"10.36348/sjpm.2022.v07i05.003","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.003","url":null,"abstract":"The Dabska tumor also known as Endovascular papillary angioendothelioma is a rare, low-grade angiosarcoma that often affects the skin and subcutaneous tissues of children is characterized by intraluminal papillary endothelial structures. EPA has an overall favorable prognosis. The malignant potential of this tumor should not be ignored and close follow-up should be maintained.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134304840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Gastrointestinal PCR on the Management of Gastrointestinal Infections in Immunocompromised Patients","authors":"Mahjouba Baiya, Asmae Lamrani Hanchi, N. Soraa","doi":"10.36348/sjpm.2022.v07i05.004","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.004","url":null,"abstract":"Introduction: Gastrointestinal infections are one of the leading causes of morbidity and mortality throughout the world, particularly in the immunocompromised. Gastrointestinal PCR appears to be the technique of choice for establishing the molecular diagnosis of pathogenic gastrointestinal agents. The aim of this study was to establish the epidemiological, clinical and evolutionary profile of gastrointestinal infections and to study the impact of molecular diagnosis on the choice of a targeted therapy. Methods: This is a retrospective study carried out in the Microbiology Department of Arrazi Hospital of the Mohamed VI University Hospital Center, including all immunocompromised patients treated for a gastrointestinal infection and needing a hospitalization in the various departments, over a period of 15 months. Results: During the period studied, 124 patients were collected. The average age of the patients was 22 years. Signs of gastrointestinal infection were present in all patients. Of the patients sampled, 95.2% received probabilistic antibiotic therapy. Gastrointestinal infection has been documented in 57.26% of patients. A bacterial etiology was found in 76.81% of patients. A viral etiology was found in 13.04% of the patients and a parasitic etiology was found in 10.15% of the patients. Enteropathogenic E. coli was the most common infectious agent detected (19.53%). Co-infections were found in 29.84% of patients. Following PCR results, management was changed in 70 patients (56.45%), including initiation or modification of antibiotics in 40 patients (32.26%) and discontinuation of antibiotic therapy in 30 patients (24.19%). Conclusion: The diagnosis of gastrointestinal infections by multiplex PCR allowed us to provide optimal patient care with a reduction in the unnecessary use of antibiotics and an improvement in the course of care.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128568606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Oral Lichenoid Reaction to Potassium Alum: A Case Report and a Review of the Literature","authors":"Olagundoye Olufemi O, Usifo Usemen E, Ladeji Adeola M, Olajide Mofoluwaso, O. D., Ndugbu Emeka","doi":"10.36348/sjpm.2022.v07i05.002","DOIUrl":"https://doi.org/10.36348/sjpm.2022.v07i05.002","url":null,"abstract":"Background: Potash alum mouth rinse has been well studied with appreciable success in protection against carious lesions and periodontal microbiota with no adverse reactions. While oral lichenoid reactions have been documented as complications of various dental materials and drugs none has been reported as a result of alum use. Case Description: An unusual oral lichenoid reaction to potash alum use in an adult patient who presented at the oral medicine and diagnosis clinic of the dental centre of the Lagos State University Teaching Hospital. He presented with complaints of excessive salivary flow and dark pigmentation of the palate, and a history of potash alum licking for more than a month. On examination a dark pigmentation involving the palatal gingiva related to 24-27, sialometry revealed normal salivary flow Hence a diagnosis of false sialorrhoea was made. The patient was referred to the Periodontology unit of the same institution where an excisional biopsy was carried out, this was diagnosed as a lichenoid reaction by the Oral Pathology unit. The patient was counselled to stop the use of alum and reassured about the normal salivary flow. The patient reported tremendous improvement on review. Conclusion: Many home remedy habits and practices can be harmful, this underscores the role of counseling patients against these unverified remedies.","PeriodicalId":407259,"journal":{"name":"Saudi Journal of Pathology and Microbiology","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130585114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}