Clinical Schizophrenia and Related Psychoses最新文献_第3页

Development and Feasibility Testing of a Smartphone Intervention to Improve Adherence to Antipsychotic Medications. 智能手机干预提高抗精神病药物依从性的开发和可行性测试。

Clinical Schizophrenia and Related Psychoses Pub Date : 2019-01-01 Epub Date: 2016-07-25 DOI: 10.3371/CSRP.KRRE.070816

Julie Kreyenbuhl, Elizabeth J Record, Seth Himelhoch, Melanie Charlotte, Jessica Palmer-Bacon, Lisa B Dixon, Deborah R Medoff, Lan Li

{"title":"Development and Feasibility Testing of a Smartphone Intervention to Improve Adherence to Antipsychotic Medications.","authors":"Julie Kreyenbuhl, Elizabeth J Record, Seth Himelhoch, Melanie Charlotte, Jessica Palmer-Bacon, Lisa B Dixon, Deborah R Medoff, Lan Li","doi":"10.3371/CSRP.KRRE.070816","DOIUrl":"https://doi.org/10.3371/CSRP.KRRE.070816","url":null,"abstract":"Approximately 60% of individuals with schizophrenia do not take their antipsychotic medications as prescribed, and nonadherence is associated with exacerbation of psychotic symptoms, increased hospital and emergency room use, and increased healthcare costs. Behavioral-tailoring strategies that incorporate medication taking into the daily routine and use environmental supports have shown promise as adherence-enhancing interventions. Informed by the Information-Motivation-Behavioral (IMB) Skills Model and using the iterative process of user-centered design, we collaborated with individuals with schizophrenia and psychiatrists to develop an interactive smartphone application and web-based clinician interface, MedActive, for improving adherence to oral antipsychotic treatment. MedActive facilitates the active involvement of individuals with schizophrenia in managing their antipsychotic medication regimen by providing automated reminders for medication administration and tailored motivational feedback to encourage adherence, and by displaying user-friendly results of daily ecological momentary assessments (EMAs) of medication adherence, positive psychotic symptoms, and medication side effects for individuals and their psychiatrists. In a 2-week open trial completed by 7 individuals with schizophrenia and their psychiatrists, MedActive was determined to be both feasible and acceptable, with patient participants responding to 80% of all scheduled EMAs and providing positive evaluations of their use of the application. Psychiatrist participants were interested in viewing the information provided on the MedActive clinician interface, but cited practical barriers to regularly accessing it and integrating into their daily practice.","PeriodicalId":40019,"journal":{"name":"Clinical Schizophrenia and Related Psychoses","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3371/CSRP.KRRE.070816","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34310883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Experience of Caregiving and Coping in Caregivers of Schizophrenia. 精神分裂症照护者的照护经验与应对。

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-09-01 DOI: 10.3371/csrp.DOSH.123015

Nimisha Doval, E. Sharma, M. Agarwal, A. Tripathi, A. Nischal

{"title":"Experience of Caregiving and Coping in Caregivers of Schizophrenia.","authors":"Nimisha Doval, E. Sharma, M. Agarwal, A. Tripathi, A. Nischal","doi":"10.3371/csrp.DOSH.123015","DOIUrl":"https://doi.org/10.3371/csrp.DOSH.123015","url":null,"abstract":"BACKGROUND\u0000Caregivers of schizophrenia play a major role in community-based care of patients. Recent studies have shed light on positive aspects of caregiving, in contrast to caregiving burden. There is limited research in this area in India.\u0000\u0000\u0000AIMS\u0000To assess the \"experience of caregiving\" and \"coping strategies\" in caregivers of patients with schizophrenia, and to study associations, if any, between them.\u0000\u0000\u0000METHOD\u0000102 caregivers of out- and in-patients with schizophrenia were assessed on the \"Experience of Caregiving Inventory\" (ECI) and \"COPE Inventory\" (COPE). Sociodemographic profiles of patients and caregivers, and clinical histories of patients were also collected.\u0000\u0000\u0000RESULTS\u0000Maximum perceived negative experience of caregiving was \"effects on family\" while \"stigma\" was the lowest. Other domains had moderate scores. Among positive experiences, \"good aspects of relationship\" scored higher than \"positive personal experiences.\" A wide range of adaptive and maladaptive coping strategies were used. Statistically significant positive correlations emerged between positive experiences of caregiving and adaptive coping strategies, and between negative experiences of caregiving and maladaptive coping strategies.\u0000\u0000\u0000CONCLUSION\u0000The association between experiences of caregiving and coping strategies suggests that caregiving experiences are influenced not only by the illness but also by the coping methods employed. Helping caregivers cope better might improve caregiving experience.","PeriodicalId":40019,"journal":{"name":"Clinical Schizophrenia and Related Psychoses","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82719713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Neurocryptococcosis in immunocompetent patient with psychosis. 免疫功能正常的精神病患者患上了神经隐球菌病。

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.FLJU.061518

Isabelly Sanally Monteiro Florentino, José Brasileiro Dourado Júnior, Amaury Cantilino

引用次数: 0

Exploring construct validity of clinical staging in schizophrenia spectrum disorders in an acute psychiatric ward. 探索急性精神病病房精神分裂症谱系障碍临床分期的构建有效性。

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.BEPA.061518

Steven Berendsen, Jasper van der Paardt, Marion van Bruggen, Hans Nusselder, Margje Jalink, Jaap Peen, Henricus Van, Jack Dekker, Lieuwe de Haan

{"title":"Exploring construct validity of clinical staging in schizophrenia spectrum disorders in an acute psychiatric ward.","authors":"Steven Berendsen, Jasper van der Paardt, Marion van Bruggen, Hans Nusselder, Margje Jalink, Jaap Peen, Henricus Van, Jack Dekker, Lieuwe de Haan","doi":"10.3371/CSRP.BEPA.061518","DOIUrl":"10.3371/CSRP.BEPA.061518","url":null,"abstract":"Objective: clinical staging and profiling of schizophrenia spectrum disorders has been proposed to describe and define the heterogenous course of disease. We examined the construct validity of clinical staging in schizophrenia spectrum disorders by measuring differences in distribution and severity of relevant clinical profilers and therapeutic improvement (HoNOS) across clinical stages.Methods: we performed a prospective cross-sectional study with 258 inpatiënts who met DSM-IV criteria for schizophrenia spectrum disorders, recruited in an acute ward of a psychiatric hospital from 1-1-2015 until 31-12-2016. All patients (N=258) were assigned to a clinical stage, according to the criteria described by McGorry and clinical profilers were determined. Therapeutic improvement was assessed by measuring change in differences in HoNOS score during admission.Results: significant higher severity scores of clinical profilers were found in more advanced stages compared to earlier stages. This pattern was apparent in the clinical profilers negative symptoms (F=4.56, P<0.01), number of psychotic episodes last year (F=13.65, P<0.01), compliance (F=2.76, P<0.05), work and daily activities (F=9.85, P<0.001), living situation (F=3.71, P<0.05), support of close relatives (F=9.38, P<0.001) and pre-morbid functioning (F=7.33, P<0.001). Judicial background was less prevalent in earlier stages compared to more advanced disease stages. No differences in therapeutic improvement (HoNOS) were found between clinical stages.Conclusion: this study demonstrates that clinical staging in schizophrenia spectrum disorders has an acceptable construct validity between earlier and more chronic stages of disease. Several clinical profilers increase in more advanced stages compared to earlier clinical stages, which supports construct validity.","PeriodicalId":40019,"journal":{"name":"Clinical Schizophrenia and Related Psychoses","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36257387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Faux-Pas Test: A Proposal of a Standardized Short Version. 伪装测试：关于标准化简短版本的建议

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.FEAR.061518

Mar Fernández-Modamio, Marta Arrieta-Rodríguez, Rosario Bengochea-Seco, Iciar Santacoloma-Cabero, Juan Gómez de Tojeiro-Roce, Bárbara García-Polavieja, Eduardo González-Fraile, Manuel Martín-Carrasco, Kim Griffin, David Gil-Sanz

{"title":"Faux-Pas Test: A Proposal of a Standardized Short Version.","authors":"Mar Fernández-Modamio, Marta Arrieta-Rodríguez, Rosario Bengochea-Seco, Iciar Santacoloma-Cabero, Juan Gómez de Tojeiro-Roce, Bárbara García-Polavieja, Eduardo González-Fraile, Manuel Martín-Carrasco, Kim Griffin, David Gil-Sanz","doi":"10.3371/CSRP.FEAR.061518","DOIUrl":"10.3371/CSRP.FEAR.061518","url":null,"abstract":"Previous research on theory of mind suggests that people with schizophrenia have difficulties with complex mentalization tasks that involve the integration of cognition and affective mental states. One of the tools most commonly used to assess theory of mind is the Faux-Pas Test. However, it presents two main methodological problems: 1) the lack of a standard scoring system; 2) the different versions are not comparable due to a lack of information on the stories used. These methodological problems make it difficult to draw conclusions about performance on this test by people with schizophrenia. The aim of this study was to develop a reduced version of the Faux-Pas test with adequate psychometric properties. The test was administered to control and clinical groups. Interrater and test-retest reliability were analyzed for each story in order to select the set of 10 stories included in the final reduced version. The shortened version showed good psychometric properties for controls and patients: test-retest reliability of 0.97 and 0.78, inter-rater reliability of 0.95 and 0.87 and Cronbach's alpha of 0.82 and 0.72.","PeriodicalId":40019,"journal":{"name":"Clinical Schizophrenia and Related Psychoses","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36258901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First-Episode Psychosis and Hypokalemia: A Case Report and Review of the Literature. 首发精神病与低钾血症：病例报告和文献综述。

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.COSA.061518

Ricardo Coentre, Rodrigo Saraiva, Pedro Levy

引用次数: 0

Premenstrual Psychosis in an Adolescent: A Case Report. 一名青少年的经前精神病：病例报告

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.FAJI.061518

Jack P Fatica, Salima Jiwani, Rabia Salman, Salman Majeed

引用次数: 0

Re-titration rates after clozapine-induced neutropenia or agranulocytosis: A case report and literature review. 氯氮平诱发中性粒细胞减少症或粒细胞减少症后的再用药率：病例报告和文献综述。

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.BOKA.061518

Mina Boazak, Benjamin Kahn, Lindsay Cox, James Ragazino, David R Goldsmith, Robert O Cotes

{"title":"Re-titration rates after clozapine-induced neutropenia or agranulocytosis: A case report and literature review.","authors":"Mina Boazak, Benjamin Kahn, Lindsay Cox, James Ragazino, David R Goldsmith, Robert O Cotes","doi":"10.3371/CSRP.BOKA.061518","DOIUrl":"10.3371/CSRP.BOKA.061518","url":null,"abstract":"Clozapine-induced neutropenia occurs in 3-5% of individuals treated with clozapine. Current US guidelines require interruption of clozapine when the absolute neutrophil count (ANC) drops below 1000 cells/mm3. There is minimal available guidance for what dosing schedule to use when restarting clozapine after an episode of neutropenia. Here, we present a case of a 50-year-old Caucasian female with a history of schizoaffective disorder who was successfully rechallenged on clozapine one month after developing clozapine-induced neutropenia (ANC 600 cells/mm3). To understand published re-titration rates of clozapine after neutropenia, we conducted a literature review using a using the PubMed database and found only seven case reports that unambiguously reported a clozapine dosing schedule during re-challenge. All were successful except one, a case of clozapine rechallenge after agranulocytosis. Including this case presentation, six out of eight cases restarted clozapine more cautiously than recommended by the US guidelines for a new clozapine initiation. We cannot comment what role a slower or more rapid titration plays in a successful rechallenge after neutropenia with the available evidence. We encourage researchers to publish their dosing schedule in detail after an episode of neutropenia or agranulocytosis.","PeriodicalId":40019,"journal":{"name":"Clinical Schizophrenia and Related Psychoses","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443488/pdf/nihms-1019026.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36258906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When Dementia Kills Before One Passes Away: Case Report of Cotard's Syndrome. 当痴呆症在人去世前夺去生命时：科塔德综合征病例报告。

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.PEFL.061518

Camila Wanderley Pereira, Isabelly Sanally Monteiro Florentino, Leonardo Machado

{"title":"When Dementia Kills Before One Passes Away: Case Report of Cotard's Syndrome.","authors":"Camila Wanderley Pereira, Isabelly Sanally Monteiro Florentino, Leonardo Machado","doi":"10.3371/CSRP.PEFL.061518","DOIUrl":"10.3371/CSRP.PEFL.061518","url":null,"abstract":"Introduction: Cotard's Syndrome (CS), among the noncognitive changes in the forms of dementia, is a seldom-found manifestation (1). This syndrome is characterized by the delusion of having lost organs (the individual experiences huge changes in the body and believes that he/she no longer has one or more organs) and by nihilistic delusion (the individual believes he/she or everyone in the world has died or been destroyed) (2). In 1880, Jules Cotard (1840-1889) described a clinical condition that he believed corresponded to a new subtype of depression, which he called anxious melancholia. He proposed that a state of acute depression and morbid anxiety could foster the development of structured delusions of hypochondria. Two years later he referred to the same clinical condition using the term délires des négations for the first time (3). The eponym CS was only introduced in 1893 by Emil Regis, who stated that Cotard had not described a new clinical entity but rather a syndrome - a cluster of symptoms that could also be found in other mental illnesses apart from depression and in which anxiety was the central characteristic (4). The most prominent symptoms found in an analysis of one hundred cases were: depressed mood (89%), nihilistic delusion (69%), anxiety (65%), delusion of guilt (63%), delusion of immortality (55%) and hypochondriacal delusions (58%) (12). Currently, CS is not classified as an isolated disorder in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) of the American Psychiatric Association or in the International Statistical Classification of Diseases and Related Health Problems (ICD-10). There is a growing consensus to consider it a secondary syndrome of an underlying disorder, of which the most associated disorders are: unipolar depression, bipolar depression and primary psychotic disorders. Other conditions have also been described, such as dementia, severe intellectual disability, cerebrovascular accident, brain tumor, and Parkinson's disease, among others (5).","PeriodicalId":40019,"journal":{"name":"Clinical Schizophrenia and Related Psychoses","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36257385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Exploratory Study of Exercise-related Effects on Memory and Hippocampal Connectivity in Schizophrenia. 运动对精神分裂症患者记忆力和海马体连接性影响的探索性研究

Clinical Schizophrenia and Related Psychoses Pub Date : 2018-06-26 DOI: 10.3371/CSRP.SCWO.061518

Barbara Schwartz, Theresa Teslovich, Xiaozhen You, Jae Cho, Nina Schooler, Peter Kokkinos, Chandan Vaidya

引用次数: 0