Expert Review of Ophthalmology最新文献_第6页

Crowdsourcing and its applications to ophthalmology 众包及其在眼科中的应用

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Expert Review of Ophthalmology Pub Date : 2023-03-04 DOI: 10.1080/17469899.2023.2200935

Junsang Cho, Wendy Zhang, Grayson W. Armstrong, Daniel Cho, S. Culican

{"title":"Crowdsourcing and its applications to ophthalmology","authors":"Junsang Cho, Wendy Zhang, Grayson W. Armstrong, Daniel Cho, S. Culican","doi":"10.1080/17469899.2023.2200935","DOIUrl":"https://doi.org/10.1080/17469899.2023.2200935","url":null,"abstract":"ABSTRACT Introduction The aim of this study was to review the literature on the application of crowdsourcing in the field of ophthalmology. As the concept of crowdsourcing continues to receive interest, this review describes an analysis of the benefits, limitations, and future directions of crowdsourcing in the context of specific cases. A search of major research databases was performed to identify articles with specific reference to crowdsourcing within the field of ophthalmology. Seventeen total studies used crowdsourcing in a branch of ophthalmology. Crowdsourcing was used in three capacities: evaluation of ophthalmic imaging, collection of data, and assessment of surgery or surgical outcomes. Crowdsourcing holds the potential for rapid, economic data processing and reducing the task burden on experts. The main limitation of crowdsourcing is the potential for error due to inexperience of lay assessors. Areas covered Crowdsourcing was applied in three capacities: evaluation of ophthalmic imaging, collection of data, and assessment of surgery or surgical outcomes. Expert opinion Crowdsourcing has been utilized within ophthalmology and holds potential for rapid, economical data processing and reducing task burden on experts. While the use of crowdsourcing may still be nascent, prior reports indicate promise. This report aims to show how crowdsourcing has been applied in ophthalmology. The main limitation of crowdsourcing has been the potential for error due to lay assessor inexperience, though a potential solution is to use trained assessors. We hope to highlight the past, present, and future of crowdsourcing within ophthalmology through this comprehensive review.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41596300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OMNI® surgical system versus iStent inject® with concomitant cataract surgery for the treatment of mild-to-moderate primary open-angle glaucoma in the United States: a cost utility analysis 在美国，OMNI®手术系统与iStent®注射合并白内障手术治疗轻至中度原发性开角型青光眼的成本效用分析

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Expert Review of Ophthalmology Pub Date : 2023-03-04 DOI: 10.1080/17469899.2023.2193685

Roberta Longo, Federico Ghinelli, Francesca Torelli, Gregory Mader, C. Masseria, Chad Patel, D. Franic, Jamie Dickerson, Dan Nguyen, L. Cantor

{"title":"OMNI® surgical system versus iStent inject® with concomitant cataract surgery for the treatment of mild-to-moderate primary open-angle glaucoma in the United States: a cost utility analysis","authors":"Roberta Longo, Federico Ghinelli, Francesca Torelli, Gregory Mader, C. Masseria, Chad Patel, D. Franic, Jamie Dickerson, Dan Nguyen, L. Cantor","doi":"10.1080/17469899.2023.2193685","DOIUrl":"https://doi.org/10.1080/17469899.2023.2193685","url":null,"abstract":"ABSTRACT Background A Markov model was developed to investigate the cost utility of the OMNI® Surgical System (OMNI®) versus iStent inject® in patients with mild to moderate primary open angle glaucoma (POAG) during concomitant cataract surgery from a US Medicare perspective. Methods For patients aged 65 years and older with mild to moderate POAG and visually significant cataract, we simulated progression through four glaucoma states (mild, moderate, advanced, severe) and death, using 6-month cycles and a lifetime horizon. A systematic literature review identified effectiveness data to calculate health state transition probabilities. Direct costs included surgical procedures, physician fees, and intraocular pressure (IOP)-lowering medications using Medicare 2022 rates. Utilities were sourced from published literature. Model structure and inputs were validated by a panel of ophthalmologists in the US and UK. Main outcome measures were incremental cost/QALY gained and net monetary benefit (NMB). Results OMNI® dominated iStent inject® with $552 lower costs and a gain of 0.02 quality-adjusted life-years. Model robustness was tested through deterministic and probabilistic sensitivity analyses, with OMNI® being dominant or cost-effective. NMB was $1,422 using a $50,000 willingness-to-pay threshold. Conclusion OMNI® was less costly and more effective than iStent inject® over a lifetime perspective for mild-to-moderate POAG Medicare patients in need of cataract extraction.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47535788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Integrating artificial intelligence into an ophthalmologist’s workflow: obstacles and opportunities 将人工智能集成到眼科医生的工作流程中:障碍和机遇

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Expert Review of Ophthalmology Pub Date : 2023-01-02 DOI: 10.1080/17469899.2023.2175672

P. Taribagil, H. J. Hogg, K. Balaskas, P. Keane

{"title":"Integrating artificial intelligence into an ophthalmologist’s workflow: obstacles and opportunities","authors":"P. Taribagil, H. J. Hogg, K. Balaskas, P. Keane","doi":"10.1080/17469899.2023.2175672","DOIUrl":"https://doi.org/10.1080/17469899.2023.2175672","url":null,"abstract":"ABSTRACT Introduction Demand in clinical services within the field of ophthalmology is predicted to rise over the future years. Artificial intelligence, in particular, machine learning-based systems, have demonstrated significant potential in optimizing medical diagnostics, predictive analysis, and management of clinical conditions. Ophthalmology has been at the forefront of this digital revolution, setting precedents for integration of these systems into clinical workflows. Areas covered This review discusses integration of machine learning tools within ophthalmology clinical practices. We discuss key issues around ethical consideration, regulation, and clinical governance. We also highlight challenges associated with clinical adoption, sustainability, and discuss the importance of interoperability. Expert opinion Clinical integration is considered one of the most challenging stages within the implementation process. Successful integration necessitates a collaborative approach from multiple stakeholders around a structured governance framework, with emphasis on standardization across healthcare providers and equipment and software developers.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43996635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of dry eye disease therapies: exploring the qualities of varenicline solution nasal spray 干眼病治疗综述:探讨伐尼克兰鼻喷雾剂的质量

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Expert Review of Ophthalmology Pub Date : 2023-01-02 DOI: 10.1080/17469899.2023.2173173

S. Bhargava, Ranjani Panda, Asma M. Azam, J. Sheppard

引用次数: 0

Upper blepharoplasty: advanced techniques and adjunctive procedures 上眼睑整形术：先进的技术和辅助程序

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Expert Review of Ophthalmology Pub Date : 2023-01-02 DOI: 10.1080/17469899.2023.2175673

Parya Abdolalizadeh, M. Kashkouli, Vahid Khamesi, N. Karimi, Hossein Ghahvehchian, L. Ghiasian

{"title":"Upper blepharoplasty: advanced techniques and adjunctive procedures","authors":"Parya Abdolalizadeh, M. Kashkouli, Vahid Khamesi, N. Karimi, Hossein Ghahvehchian, L. Ghiasian","doi":"10.1080/17469899.2023.2175673","DOIUrl":"https://doi.org/10.1080/17469899.2023.2175673","url":null,"abstract":"ABSTRACT Introduction Various techniques of upper blepharoplasty are used to correct dermatochalasis as the common sign of aging in periorbital areas. Most patients seeking upper eyelid rejuvenation have other involutional changes in upper face which can be addressed as adjunct to upper blepharoplasty procedure to yield better esthetic and functional outcomes. Areas covered The aim of the present study is to review current concepts in preoperative considerations, surgical techniques, and adjuvant procedures of upper blepharoplasty. The role of social media is also discussed in this arena. A literature search was performed in PubMed database of English-language journals with no restriction on the date of publication using selected keywords. The relevant articles were selected by reviewing the titles and abstracts. Expert opinion Careful preoperative examination of midface and upper face is necessary to assess concomitant ageing deformities besides dermatochalasis. Nowadays, volume preservation approach is the mainstream in upper blepharoplasty. Upper blepharoplasty incisions can be used to address lacrimal gland prolapse, blepharoptosis, Asian medial epicanthoplasty and eyebrow ptosis in selected individuals.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44803106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corneal transplantation in children - when and how? 儿童角膜移植-何时以及如何进行?

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Expert Review of Ophthalmology Pub Date : 2023-01-02 DOI: 10.1080/17469899.2023.2177153

Abha Gour, A. Garg, Shailja Tibrewal, Julie Pegu, Sonal Gupta, Umang Mathur, V. Sangwan

{"title":"Corneal transplantation in children - when and how?","authors":"Abha Gour, A. Garg, Shailja Tibrewal, Julie Pegu, Sonal Gupta, Umang Mathur, V. Sangwan","doi":"10.1080/17469899.2023.2177153","DOIUrl":"https://doi.org/10.1080/17469899.2023.2177153","url":null,"abstract":"ABSTRACT Introduction Advanced surgical techniques, better post-operative protocols, imaging, and better understanding of genetic basis have enhanced outcomes of pediatric keratoplasty. However, results in infants and younger children remain a challenge. Transplants in the pediatric age group are challenging because of the complexity of the indications, the procedure itself, and the problems with respect to follow-up and post-operative care in younger recipients. Areas covered This review presents an overview of challenges faced in the management of pediatric corneal grafts, and problems encountered in long-term survival. We discuss the changing trends in these outcomes of PKP with a current review of the recent literature from PubMed. We also share the results of pediatric keratoplasty done at our center in the last three years and have an in-depth discussion about the management of comorbidities like cataracts and glaucoma Expert opinion Despite several advances in microsurgical techniques for corneal transplantation, pediatric keratoplasty remains challenging due to a variety of factors such as young age, repeated need for anesthesia, immature ocular tissues, and accelerated healing. The advent of component surgeries like DALK, DSEK, and DMEK has improved outcomes and simplified management options. Even after specialized surgeries, long-term follow-ups and management of comorbidities become essential.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48727120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Factors affecting the prevalence, severity, and characteristics of ocular surface pain. 影响眼表疼痛发生率、严重程度和特征的因素。

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Expert Review of Ophthalmology Pub Date : 2023-01-01 Epub Date: 2022-12-18 DOI: 10.1080/17469899.2023.2157813

Victor Sanchez, Noah K Cohen, Elizabeth Felix, Anat Galor

{"title":"Factors affecting the prevalence, severity, and characteristics of ocular surface pain.","authors":"Victor Sanchez, Noah K Cohen, Elizabeth Felix, Anat Galor","doi":"10.1080/17469899.2023.2157813","DOIUrl":"10.1080/17469899.2023.2157813","url":null,"abstract":"Introduction: Ocular surface pain has been traditionally lumped under the umbrella term \"dry eye\" (DE) but is now understood as its own entity and can occur in the absence or presence of tear dysfunction. Identifying patients at risk for the development of chronic ocular surface pain, and factors contributing to its severity are important in providing precision medicine to patients.Areas covered: In this review, we discuss factors linked to the presence and severity of ocular surface pain, including eye related features, systemic characteristics, and environmental findings. We discuss corneal nerves, whose anatomic and functional integrity can be characterized through in vivo confocal microscopy images and testing of corneal sensitivity. We review systemic diseases that are co-morbid with ocular surface pain, including physical and mental health diagnoses. Finally, we identify environmental contributors, including air pollution, previous surgeries, and medications, associated with ocular surface pain.Expert opinion: Intrinsic and extrinsic factors contribute to ocular surface pain and must be considered when evaluating an individual patient. These factors can inform the suspected etiology of the pain, and guide management decisions such as tear replacement or medications targeting nerve pain.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9287616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging glaucoma treatments: are we seeing an improvement in adherence? 新兴的青光眼治疗方法：我们是否看到依从性有所改善？

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Expert Review of Ophthalmology Pub Date : 2023-01-01 Epub Date: 2023-04-12 DOI: 10.1080/17469899.2023.2199981

Andrew P Droste, Paula Anne Newman-Casey

{"title":"Emerging glaucoma treatments: are we seeing an improvement in adherence?","authors":"Andrew P Droste, Paula Anne Newman-Casey","doi":"10.1080/17469899.2023.2199981","DOIUrl":"10.1080/17469899.2023.2199981","url":null,"abstract":"Introduction: Non-adherence to glaucoma medication and poor follow-up is a global health concern.Areas covered: Glaucoma remains one of the largest causes of irreversible blindness worldwide. Traditional treatment guidelines suggest topical eye drop medication as first line therapy followed by addition of supplementary medications before proceeding to more invasive glaucoma surgeries. Unfortunately, poor glaucoma self-management remains high, leading to disease progression and blindness. Recent advancements in the field of pharmacotherapies, surgeries, and behavioral approaches have taken aim at increasing support for glaucoma self-management. We review the current and emerging approaches towards glaucoma management, with the exception of bleb-based surgical approaches, to investigate if they have had an impact on adherence. Literature searches were conducted via MEDLINE (PubMed), Embase (Elsevier), Cochrane Library (Wiley), and Preprints from January 1st, 2018, to January 26th, 2023.Expert opinion: The ability to offer patients a multitude of choices enables patients to tailor their glaucoma treatment to their values and lifestyle. Offering personalized patient education and coaching to support chronic glaucoma self-management would better enable patient engagement in whichever treatment path is chosen. Currently, literature regarding the impact of these new advancements on treatment engagement is lacking; this field is ripe for additional intervention and assessment.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10300338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How can the safety of antibody therapy for retinopathy of prematurity be improved? 如何提高早产儿视网膜病变抗体疗法的安全性？

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Expert Review of Ophthalmology Pub Date : 2023-01-01 Epub Date: 2023-04-09 DOI: 10.1080/17469899.2023.2200934

M Elizabeth Hartnett

引用次数: 0

Evaluating gap junction variants for a role in pediatric cataract: an overview of the genetic landscape and clinical classification of variants in the GJA3 and GJA8 genes 评估间隙连接变异在儿童白内障中的作用:GJA3和GJA8基因变异的遗传景观和临床分类概述

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Expert Review of Ophthalmology Pub Date : 2022-12-20 DOI: 10.1080/17469899.2023.2160320

Johanna L Jones, K. Burdon

{"title":"Evaluating gap junction variants for a role in pediatric cataract: an overview of the genetic landscape and clinical classification of variants in the GJA3 and GJA8 genes","authors":"Johanna L Jones, K. Burdon","doi":"10.1080/17469899.2023.2160320","DOIUrl":"https://doi.org/10.1080/17469899.2023.2160320","url":null,"abstract":"ABSTRACT Introduction Variants in the two lens-expressed gap junction genes GJA3 and GJA8 are among the most common causes of inherited pediatric cataract. These two genes alone account for up to 18% of the cases, second only to the crystallin gene family. Areas covered All published cataract-associated variants in the GJA3 and GJA8 genes were reviewed for a role in pediatric cataract. Autosomal dominant inheritance was most frequently reported, alongside instances of reduced penetrance and autosomal recessive disease. Variant curation using the ACMG-AMP guidelines identified that many variants do not meet the modern standards for clinical interpretation of pathogenicity. There is broad phenotypic heterogeneity of cataract associated with gap junction gene variants. Pathogenic variants are located throughout both proteins with an enrichment in the N-terminal, first two transmembrane domains, and two extracellular loops. Expert opinion Nearly half the gap junction gene variants observed in cataract patients lack sufficient evidence of pathogenicity to form a useful clinical opinion. For many variants, this may be rectified over time as the variant is observed in additional patients but would be vastly accelerated by the generation of well-characterized and standardized functional data evaluating the specific effect of each variant on protein function.","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47285428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1