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Expert Review of Ophthalmology最新文献

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Systemic and Ocular Associations of Keratoconus. 角膜炎的全身和眼部关联。
IF 0.9
Expert Review of Ophthalmology Pub Date : 2024-01-01 Epub Date: 2024-07-03 DOI: 10.1080/17469899.2024.2368801
Brenna S Hefley, Arsalan A Ali, Pradipta Bhattacharya, Jesper Hjortdal, Maria K Walker, Dimitrios Karamichos
{"title":"Systemic and Ocular Associations of Keratoconus.","authors":"Brenna S Hefley, Arsalan A Ali, Pradipta Bhattacharya, Jesper Hjortdal, Maria K Walker, Dimitrios Karamichos","doi":"10.1080/17469899.2024.2368801","DOIUrl":"10.1080/17469899.2024.2368801","url":null,"abstract":"<p><strong>Introduction: </strong>Keratoconus (KC) is the most prevalent corneal ectasia in the world and its pathogenesis is influenced by both ocular and systemic factors. This review explores the multifaceted associations between keratoconus and systemic health conditions, ocular characteristics, and various other environmental/exogenous factors, aiming to illuminate how these relationships influence the pathophysiology of the disease.</p><p><strong>Areas covered: </strong>This review will summarize the fundamental attributes of KC, review and discuss the systemic and ocular association of KC including molecular biomarkers, and provide an organized overview of the parallel alterations occurring within various biological pathways in KC.</p><p><strong>Expert opinion: </strong>Despite the substantial volume of research on keratoconus, the precise etiology of the disease remains elusive. Further studies are necessary to deepen our understanding of this intricate disorder and improve its management.</p>","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"19 5","pages":"379-391"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How Genome-Wide Association Studies Transform Care for Patients at Risk of Glaucoma. 全基因组关联研究如何改变对青光眼风险患者的护理。
IF 0.9
Expert Review of Ophthalmology Pub Date : 2024-01-01 Epub Date: 2024-06-19 DOI: 10.1080/17469899.2024.2365736
Nazlee Zebardast, Janey L Wiggs
{"title":"How Genome-Wide Association Studies Transform Care for Patients at Risk of Glaucoma.","authors":"Nazlee Zebardast, Janey L Wiggs","doi":"10.1080/17469899.2024.2365736","DOIUrl":"10.1080/17469899.2024.2365736","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"19 4","pages":"243-246"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spaceflight associated neuro-ocular syndrome (SANS): a systematic review, implications for the sans case definition 太空飞行相关神经眼综合征（SANS）：系统回顾，对 SANS 病例定义的影响
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-12-26 DOI: 10.1080/17469899.2023.2296884
A. Elgenidy, Aya Hesham, Mostafa Atef, Ahmed Awad, Abdullah Emad, Omar Alomari, Ramez M. Odat, Andrew G Lee
{"title":"Spaceflight associated neuro-ocular syndrome (SANS): a systematic review, implications for the sans case definition","authors":"A. Elgenidy, Aya Hesham, Mostafa Atef, Ahmed Awad, Abdullah Emad, Omar Alomari, Ramez M. Odat, Andrew G Lee","doi":"10.1080/17469899.2023.2296884","DOIUrl":"https://doi.org/10.1080/17469899.2023.2296884","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"14 20","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stem cell therapy in retinal diseases: current evidence 干细胞治疗视网膜疾病：现有证据
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-12-20 DOI: 10.1080/17469899.2023.2296895
Leopoldo Rubinato, Enrico Redolfi de Zan, Valentina Sarao, Daniele Veritti, P. Lanzetta
{"title":"Stem cell therapy in retinal diseases: current evidence","authors":"Leopoldo Rubinato, Enrico Redolfi de Zan, Valentina Sarao, Daniele Veritti, P. Lanzetta","doi":"10.1080/17469899.2023.2296895","DOIUrl":"https://doi.org/10.1080/17469899.2023.2296895","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"47 2","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphometric analysis of orbital CT scan in a Jordanian sample 约旦样本眼眶 CT 扫描的形态计量分析
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-12-16 DOI: 10.1080/17469899.2023.2296882
Muawyah Al Bdour, Dima Abu Nasrieh, Farah Al Omari, Walid Mahafzah, Darwish Badran, Abdul Hakeem AL-Obaidy, S. A. Alryalat
{"title":"Morphometric analysis of orbital CT scan in a Jordanian sample","authors":"Muawyah Al Bdour, Dima Abu Nasrieh, Farah Al Omari, Walid Mahafzah, Darwish Badran, Abdul Hakeem AL-Obaidy, S. A. Alryalat","doi":"10.1080/17469899.2023.2296882","DOIUrl":"https://doi.org/10.1080/17469899.2023.2296882","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"58 41","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinoic acid loaded with chitosan nanoparticles improves spermatogenesis in scrotal hyperthermia in mice. 载壳聚糖纳米颗粒维甲酸可改善小鼠阴囊高温下精子的发生
IF 1.8
Expert Review of Ophthalmology Pub Date : 2023-12-01 Epub Date: 2023-09-08 DOI: 10.5653/cerm.2023.06149
Fatemeh Mazini, Mohammad-Amin Abdollahifar, Hassan Niknejad, Asma Manzari-Tavakoli, Mohsen Zhaleh, Reza Asadi-Golshan, Ali Ghanbari
{"title":"Retinoic acid loaded with chitosan nanoparticles improves spermatogenesis in scrotal hyperthermia in mice.","authors":"Fatemeh Mazini, Mohammad-Amin Abdollahifar, Hassan Niknejad, Asma Manzari-Tavakoli, Mohsen Zhaleh, Reza Asadi-Golshan, Ali Ghanbari","doi":"10.5653/cerm.2023.06149","DOIUrl":"10.5653/cerm.2023.06149","url":null,"abstract":"<p><strong>Objective: </strong>High temperatures can trigger cellular oxidative stress and disrupt spermatogenesis, potentially leading to male infertility. We investigated the effects of retinoic acid (RA), chitosan nanoparticles (CHNPs), and retinoic acid loaded with chitosan nanoparticles (RACHNPs) on spermatogenesis in mice induced by scrotal hyperthermia (Hyp).</p><p><strong>Methods: </strong>Thirty mice (weighing 25 to 30 g) were divided into five experimental groups of six mice each. The groups were as follows: control, Hyp induced by a water bath (43 °C for 30 minutes/day for 5 weeks), Hyp+RA (2 mg/kg/day), Hyp+CHNPs (2 mg/kg/72 hours), and Hyp+RACHNPs (4 mg/kg/72 hours). The mice were treated for 35 days. After the experimental treatments, the animals were euthanized. Sperm samples were collected for analysis of sperm parameters, and blood serum was isolated for testosterone measurement. Testis samples were also collected for histopathology assessment, reactive oxygen species (ROS) evaluation, and RNA extraction, which was done to compare the expression levels of the bax, bcl2, p53, Fas, and FasL genes among groups. Additionally, immunohistochemical staining was performed.</p><p><strong>Results: </strong>Treatment with RACHNPs significantly increased stereological parameters such as testicular volume, seminiferous tubule length, and testicular cell count. Additionally, it increased testosterone concentration and improved sperm parameters. We observed significant decreases in ROS production and caspase-3 immunostaining in the RACHNP group. Moreover, the expression levels of bax, p53, Fas, and FasL significantly decreased in the groups treated with RACHNPs and RA.</p><p><strong>Conclusion: </strong>RACHNPs can be considered a potent antioxidative and antiapoptotic agent for therapeutic strategies in reproductive and regenerative medicine.</p>","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"11 1","pages":"230-243"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10711251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82036522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunopathogenesis of ocular toxoplasmosis and implications for treatment 眼弓形虫病的免疫发病机制及对治疗的影响
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-11-29 DOI: 10.1080/17469899.2023.2279178
J. Gomez Marin, Alejandra de la Torre, Mónica Vargas-Montes
{"title":"Immunopathogenesis of ocular toxoplasmosis and implications for treatment","authors":"J. Gomez Marin, Alejandra de la Torre, Mónica Vargas-Montes","doi":"10.1080/17469899.2023.2279178","DOIUrl":"https://doi.org/10.1080/17469899.2023.2279178","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"113 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139211688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rod mediated dark adaptation, a functional test for early and intermediate AMD outcomes 视杆细胞介导的暗适应，对早期和中期老年黄斑变性结果的功能测试
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-11-23 DOI: 10.1080/17469899.2023.2287178
Cynthia Owsley, Thomas A. Swain, Deepayan Kar, C. Curcio
{"title":"Rod mediated dark adaptation, a functional test for early and intermediate AMD outcomes","authors":"Cynthia Owsley, Thomas A. Swain, Deepayan Kar, C. Curcio","doi":"10.1080/17469899.2023.2287178","DOIUrl":"https://doi.org/10.1080/17469899.2023.2287178","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"18 ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139242824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting the complement system in geographic atrophy: mechanisms and therapeutics 针对地理萎缩中的补体系统：机制与疗法
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-11-20 DOI: 10.1080/17469899.2023.2286607
Majid Khan, Olawale E. Akinyemi, Maliha Masud, Mathew J. Thomas, Nicholas Martin, A. Khanani
{"title":"Targeting the complement system in geographic atrophy: mechanisms and therapeutics","authors":"Majid Khan, Olawale E. Akinyemi, Maliha Masud, Mathew J. Thomas, Nicholas Martin, A. Khanani","doi":"10.1080/17469899.2023.2286607","DOIUrl":"https://doi.org/10.1080/17469899.2023.2286607","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"5 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining correlation between ocular microbiome and ocular diseases including keratitis 研究眼部微生物群与包括角膜炎在内的眼部疾病之间的相关性
IF 0.7
Expert Review of Ophthalmology Pub Date : 2023-11-20 DOI: 10.1080/17469899.2023.2284313
S. Shivaji
{"title":"Examining correlation between ocular microbiome and ocular diseases including keratitis","authors":"S. Shivaji","doi":"10.1080/17469899.2023.2284313","DOIUrl":"https://doi.org/10.1080/17469899.2023.2284313","url":null,"abstract":"","PeriodicalId":39989,"journal":{"name":"Expert Review of Ophthalmology","volume":"48 3","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139255383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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