Nano-Structures & Nano-Objects最新文献

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Photodynamic therapy based on metal-organic framework in cancer treatment: A comprehensive review of integration strategies for synergistic combination therapies 基于金属有机框架的光动力疗法在癌症治疗中的应用:综合评述协同组合疗法的整合策略
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-10 DOI: 10.1016/j.nanoso.2024.101315
Maryam Karbasi , Mohammad Varzandeh , Minoo Karbasi , Amirali Iranpour Mobarakeh , Mahtab Falahati , Michael R. Hamblin
{"title":"Photodynamic therapy based on metal-organic framework in cancer treatment: A comprehensive review of integration strategies for synergistic combination therapies","authors":"Maryam Karbasi ,&nbsp;Mohammad Varzandeh ,&nbsp;Minoo Karbasi ,&nbsp;Amirali Iranpour Mobarakeh ,&nbsp;Mahtab Falahati ,&nbsp;Michael R. Hamblin","doi":"10.1016/j.nanoso.2024.101315","DOIUrl":"10.1016/j.nanoso.2024.101315","url":null,"abstract":"<div><p>Recent advancements in cancer therapy have prompted the exploration of innovative and synergistic treatment modalities to minimize side effects and enhance efficacy. Photodynamic therapy (PDT) leverages the ability of photosensitizers (PS) to produce reactive oxygen species (ROS) mediated by molecular oxygen and light. Metal-Organic Framework (MOF) materials are distinguished by their high porosity, abundant surface functional groups, and tunable chemophysical characteristics, which allows for the engineering of nanoparticles for diverse therapies and imaging applications. These characteristics originate from the building blocks of MOFs, which are metallic ions or clusters and organic constituents. This paper outlines a systematic path, beginning with the history, principles, and mechanism of PDT in cancer therapy. Since combining MOF-based PDT with other treatment modalities has shown promising results in preclinical studies, further optimization of these combination strategies is needed to maximize the therapeutic efficacy. So, the novelty of this review stems from the comprehensive systematic exploration of the recent advances of MOFs- and nMOFs-based PDT in cancer mono- and multi-therapy.</p></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"40 ","pages":"Article 101315"},"PeriodicalIF":5.45,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabric-based intelligent fire-warning and flame-retardant coating: A review of advances, challenges and prospects 基于织物的智能火灾预警和阻燃涂层:进展、挑战和前景综述
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-09 DOI: 10.1016/j.nanoso.2024.101328
Guangyi Zhang, Shusheng Wu, Xichen Xu, Zaihong Wei, Bihe Yuan
{"title":"Fabric-based intelligent fire-warning and flame-retardant coating: A review of advances, challenges and prospects","authors":"Guangyi Zhang,&nbsp;Shusheng Wu,&nbsp;Xichen Xu,&nbsp;Zaihong Wei,&nbsp;Bihe Yuan","doi":"10.1016/j.nanoso.2024.101328","DOIUrl":"10.1016/j.nanoso.2024.101328","url":null,"abstract":"<div><p>Fabric-based fire-warning and flame-retardant coatings could achieve dual functions of active warning response and passive fire retardancy. In contrast to conventional fire detection systems that necessitate installation at designated locations, the contact surface between the coating sensing material and the flame is substantially augmented. Therefore, it possesses crucial application value in enhancing the warning efficiency and fire safety performance of flammable substrates. This review primarily delved into the flame retardancy and fire warning of fabric coating materials. It thoroughly examined the current research status of fabric-based flame-retardant coatings and analyzed the fire-warning mechanisms of voltage-based and resistance-based coatings. Furthermore, this comprehensive review elucidated the research and current applications of various coatings based on sensing materials such as graphene oxide, carbon nanotubes, and MXene in the fire warning and flame resistance. Additionally, it is worth noting that the current functionality of fabric-based coatings is relatively limited, necessitating the incorporation of multi-functionality to adapt to various usage scenarios. In addition, it is necessary to develop large-scale coating preparation technique to achieve commercial production and combine artificial intelligence technology to achieve higher-level fire warning and flame-resistant application. Finally, the future development trend of the fabric-based coating was prospected.</p></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"40 ","pages":"Article 101328"},"PeriodicalIF":5.45,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An overview of bio-assisted nanoparticles: Synthesis, application and challenges in nature's toolbox 生物辅助纳米粒子概述:大自然工具箱中的合成、应用与挑战
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-07 DOI: 10.1016/j.nanoso.2024.101317
Kazi Sabnam Banu, Prateeti Chakraborty
{"title":"An overview of bio-assisted nanoparticles: Synthesis, application and challenges in nature's toolbox","authors":"Kazi Sabnam Banu, Prateeti Chakraborty","doi":"10.1016/j.nanoso.2024.101317","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101317","url":null,"abstract":"Nanomaterials (NMs) are distinct chemical substances that possess an extraordinarily large surface area and exterior dimensions within the nano scale range, specifically between 1 and 100 nanometers. Nano materials are categorized as inorganic NMs, organic NMs, carbon containing NMs, and composite NMs. The comprehensive examination of NMs encompasses a wide range of investigation in the field of nano technology, nano engineering, and nano science. The current imperative is for researchers to synthesize NMs due to it’s huge application in versatile areas. Different materials such as metal oxides, polymeric compounds, semiconductors, ceramics, metals etc.are utilized to synthesize nanostructures by different processes. NMs of different morphology have been synthesized based on the specific synthetic procedure and origin of the materials. Out of the several procedures, biosynthesis, also known as green synthesis or bio-assisted method, is the most environmentally benign, low-toxic and cost-effective procedure. The main aim of this job is to give a brief overview of the different naturally existing NMs, their sources amd different bio-assisted methods with the mechanisms. Three types of biogenic synthesis with the involvement of microorganisms, biomolecules as templates and plant extracts are discussed thoroughly. This review not only examines the synthesis of biogenic nanoparticles but also investigates various applications of these NMs and explores different categorizations of NMs that have been produced by environmentally sustainable techniques. The present article paper examines the underexplored field of NMs and its potential for advancements in near future.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"77 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and magnetic properties of aluminium substituted Ni-Cu spinel ferrite 铝取代镍铜尖晶石铁氧体的结构和磁性能
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-06 DOI: 10.1016/j.nanoso.2024.101325
P.B. Wasnik, K.G. Rewatkar, S.M. Suryawanshi, M.S. Bisen, S.D. Rokade
{"title":"Structural and magnetic properties of aluminium substituted Ni-Cu spinel ferrite","authors":"P.B. Wasnik, K.G. Rewatkar, S.M. Suryawanshi, M.S. Bisen, S.D. Rokade","doi":"10.1016/j.nanoso.2024.101325","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101325","url":null,"abstract":"Nickel-Copper spinel ferrite nanoparticles (NPs) with NiCuAlFeO with varying amounts of Aluminium (x = 0, 0.04,0.08,0.12) were synthesized using the microwave aided sol-gel method. The samples were analyzed using X-ray diffraction (XRD) to determine their structure. It was discovered that all the samples exhibited a cubic spinel structure and belonged to the Fd-3m space group. The crystallite size was found to be decreased from 45.21 nm to 37.34 nm with Al substitution. The TEM micrograph exhibits a nearly spherical morphology, with an average particle size of around 24.88 - 31.82 nm. The smooth M-H curve indicates the soft magnetic nature of prepared nanoparticles (NPs). The observed saturation magnetization (Ms) and coercivity (Hc) were found to initially increase until x=0.04, decreasing from 30.009 emu/g to 26.951 emu/g and 177.76 Oe to 164.20 Oe, respectively. This decrease is because of the decrease in nanocrystalline size and the distribution of cations in the spinel.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"169 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-proliferative activities of Carthamidin mediated gold nanoparticles against breast cancer: An in-vitro approach 胭脂虫酰胺介导的金纳米粒子对乳腺癌的抗增殖活性:体外方法
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-06 DOI: 10.1016/j.nanoso.2024.101324
John Joseph, Rajkuberan Chandrasekaran, Selvakumari Palani
{"title":"Anti-proliferative activities of Carthamidin mediated gold nanoparticles against breast cancer: An in-vitro approach","authors":"John Joseph, Rajkuberan Chandrasekaran, Selvakumari Palani","doi":"10.1016/j.nanoso.2024.101324","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101324","url":null,"abstract":"Natural pigments have unique commercial properties and are a versatile resource. Additionally, these pigments have potent therapeutic qualities that could be developed into a medication. With this rationale, a simple one-pot synthesis of gold nanoparticles (AuNPs) was achieved using Carthamidin (CT). The synthesis of gold nanoparticles was visually confirmed by the change of color pattern from yellow to dark purple color. The CTAuNPs exhibit Surface Plasmon Resonance at 537 nm in Ultra-Violet Visible Spectroscopy analysis (UV-Vis). The face-centered cubic crystalline nature of CTAuNPs was determined by the X-ray diffraction spectrum. The spherical, polydispersed, stable nanoparticles with an average size of 35 nm are depicted by scanning and transmission electron microscopy and CTAuNPs were stable as determined by zeta potential. The CTAuNPs were evaluated as a cytotoxic agent in the MCF 7 cells using the (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide) (MTT) method. The assay inhibits the cell proliferation in a dose-dependent manner with an IC 76.32 µg/mL. Additionally, we used the Reactive Oxygen Species assay, Lactate Dehydrogenase assay, and Acridine Orange/Ethidium Bromide Staining to annotate the apoptosis pattern. These comprehensive assays validate that the MCF 7 cancer cells treated with CTAuNPs underwent apoptosis-mediated cell death. Furthermore, flow cytometry analysis showed that the CTAuNPs stop the cell cycle at the GO/G1 phase in the MCF 7 cells. It is clear from the analyses that CTAuNPs induce apoptosis in MCF 7 cells. As a result, the development of novel pigment-based gold nanoparticles will enhance the nanoparticles as a theranostic agent as a new paradigm to combat breast cancer and resistance.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"109 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crystallization behavior of electro-spun Ag-SnO2 nanofibers through voltage-dependent alteration in Sn-interstitials 电纺 Ag-SnO2 纳米纤维的结晶行为取决于锡间质的电压变化
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-06 DOI: 10.1016/j.nanoso.2024.101316
Hafiz Aamir Sohail, Ameena Nazneen
{"title":"Crystallization behavior of electro-spun Ag-SnO2 nanofibers through voltage-dependent alteration in Sn-interstitials","authors":"Hafiz Aamir Sohail, Ameena Nazneen","doi":"10.1016/j.nanoso.2024.101316","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101316","url":null,"abstract":"One-dimensional nanomaterials have a wide range of applications, including optoelectronics, electronic, and electro-chemical, among others. In this study, we focused on investigating the structural, thermal and optical properties of the Ag-SnO nanofibers. The Ag-SnO nanofibers, were synthesized by using electrospinning technique by applying different DC voltages. The average fiber diameter increased with the increase in applied voltages. The X-ray Diffraction (XRD) analysis, reveal the formation of polycrystalline Ag-SnO nanostructures. Inconsistent variation in crystallinity was observed at different voltages, with maximum crystallinity observed at 14 kV. The Photoluminescence (PL) indicates the presence of Sn-interstitials. The 82 nm synthesized nanofibers at 14 kV observed to have maximum crystalline quality and minimum defect concentration. A pre-requisite for their use in sensors.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"166 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanocarriers for nutraceutical delivery: A miniaturized revolution in health 用于营养保健品输送的纳米载体:健康领域的微型化革命
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-06 DOI: 10.1016/j.nanoso.2024.101321
Rajashri B. Sawant, Sonali P. Nikam, Arpita Roy, Ashish Kumar, Osama A. Mohammed, Kuldeep Sharma, Ashutosh Kumar Rai, Amit Roy, Ashish Gaur, Rajan Verma
{"title":"Nanocarriers for nutraceutical delivery: A miniaturized revolution in health","authors":"Rajashri B. Sawant, Sonali P. Nikam, Arpita Roy, Ashish Kumar, Osama A. Mohammed, Kuldeep Sharma, Ashutosh Kumar Rai, Amit Roy, Ashish Gaur, Rajan Verma","doi":"10.1016/j.nanoso.2024.101321","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101321","url":null,"abstract":"With the development of nanocarriers, especially in the area of nutraceutical delivery, the rapidly expanding field of nanotechnology has brought in a new age of health and well-being. The revolutionary potential of nanocarriers to improve the stability, bioavailability, and effectiveness of nutraceutical substances is discussed in this review paper. It started with outlining the difficulties that conventional nutraceutical delivery systems have, such as their low solubility and restricted absorption, which frequently obstruct their therapeutic advantages. The various types of nanocarriers which act as nutraceuticals includes liposomes, lipids, and polymer-based materials also highlight of their special qualities and how they get around the problems outlined. Recent developments in nanocarrier technology are critically analyzed to show how these tiny particles may be designed to offer enhanced protection against bioactive compounds and targeted, controlled release. Here toxicity issues and international guidelines compliance while examining safety and regulatory factors relevant to the use of nanocarriers in nutraceuticals has also been discussed. This review concludes with a prospective outlook on the use of nanocarriers in nutraceuticals going ahead, highlighting the possibility of tailored nutrition and the significance of new developments in maintaining and averting illness. This review provides the present status and future prospects of nanocarrier technology in the improvement of nutraceutical delivery by merging recent research findings and expert perspectives.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"87 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of air annealing on structural, textural, thermal, magnetic and photocatalytic properties of Ag-doped mesoporous amorphous crystalline nanopowders Bi2O3 空气退火对掺银介孔无定形结晶纳米粉体 Bi2O3 的结构、纹理、热、磁和光催化性能的影响
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-05 DOI: 10.1016/j.nanoso.2024.101319
V.G. Ilves, V.S. Gaviko, A.M. Murzakaev, S.Y. Sokovnin, O.A. Svetlova, M.G. Zuev, M.A. Uimin
{"title":"Effect of air annealing on structural, textural, thermal, magnetic and photocatalytic properties of Ag-doped mesoporous amorphous crystalline nanopowders Bi2O3","authors":"V.G. Ilves, V.S. Gaviko, A.M. Murzakaev, S.Y. Sokovnin, O.A. Svetlova, M.G. Zuev, M.A. Uimin","doi":"10.1016/j.nanoso.2024.101319","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101319","url":null,"abstract":"Ag doped BiO nanopowders (NPs) were produced by pulsed electron beam evaporation (PEBE) under vacuum. The solid phase synthesis in an electric furnace on air was used for silver doping of bismuth oxide. Different physicochemical properties of NPs have been studied. The specific surface area of (SSA) Ag- BiO NPs was 23.7 m/g. Air annealing (200 °C) caused decreased crystallinity and an increase in the SSA of both pure and Ag-doped bismuth oxide. The dominant phase in not annealed/annealed Ag doped BiO NPs at 200 °C and 300 °C was β -phase BiO. The thermal stability of the pure and Ag-doped BiO NPs was maintained at 300–350 °C. The phase transition β→α occurred with a further increase in temperature. The annealing temperature could effectively change the physicochemical properties of the BiO NPs.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"5 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green synthesis and characterization studies of TiO2 nanoparticles and its potential biological performance TiO2 纳米粒子的绿色合成和表征研究及其潜在的生物性能
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-04 DOI: 10.1016/j.nanoso.2024.101322
R. Ramya, G. Muthulakshmi, S. Sudhahar, A. Bhaskaran
{"title":"Green synthesis and characterization studies of TiO2 nanoparticles and its potential biological performance","authors":"R. Ramya, G. Muthulakshmi, S. Sudhahar, A. Bhaskaran","doi":"10.1016/j.nanoso.2024.101322","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101322","url":null,"abstract":"Recent interest was been sparked by the potential of eco-friendly nanomaterials against human pathogenic bacteria’s and cancer cells. In the first method, TiO was obtained from green synthesis method by using seed extraction. In the second method, TiO nanoparticles were chemically synthesized by using the sol-gel process. Powder XRD, UV-Vis, ATR-IR, FESEM with EDAX, and HR-TEM were used to analyze the characteristics of the synthesized TiO nanoparticles. XRD results showed the well-developed crystallized smaller particles. The sizes of the crystalline particles were estimated by using Size-Strain Plot (SSP). The disc diffusion method was used to examine the antibacterial activity of TiO nanoparticles against gram bacteria. The synthesized TiO nanoparticles showed the largest inhibition zone and found to be more antibacterial against gram-negative bacteria. When using the green synthesized nanoparticles at a dose of 1000 µg/mL, the largest zone of inhibition against measured 15 mm. Then, the chemically synthesized TiO had the same concentration exhibited 7 mm inhibition zone. Cytotoxicity activities of human breast cancer cell were evolved by using MTT assay and their observation were showed more efficient cytotoxicity of green synthesized TiO nanoparticles compared to the chemically synthesized TiO nanoparticles. The antioxidant activity potential of green and chemically synthesized titanium dioxide nanoparticles was examined and the maximum inhibition in 400 µg/mL concentrations was reported to be 53 % and 45 %, respectively. Bovine Serum Albumin (BSA) denaturation technique revealed the significant anti-inflammatory action of green synthesized TiO, with protein denaturation of egg albumin determined as 92.2 % at 400 µg/mL concentration.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"23 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential in vitro antibacterial and anticancer properties of biosynthesized multifunctional silver nanoparticles using Martynia annua L. leaf extract 利用茉莉花叶提取物生物合成的多功能银纳米粒子的潜在体外抗菌和抗癌特性
IF 5.45
Nano-Structures & Nano-Objects Pub Date : 2024-09-04 DOI: 10.1016/j.nanoso.2024.101320
Megha B. Abbigeri, Bothe Thokchom, Santosh Mallikarjun Bhavi, Sapam Riches Singh, Pooja Joshi, Ramesh Babu Yarajarla
{"title":"Potential in vitro antibacterial and anticancer properties of biosynthesized multifunctional silver nanoparticles using Martynia annua L. leaf extract","authors":"Megha B. Abbigeri, Bothe Thokchom, Santosh Mallikarjun Bhavi, Sapam Riches Singh, Pooja Joshi, Ramesh Babu Yarajarla","doi":"10.1016/j.nanoso.2024.101320","DOIUrl":"https://doi.org/10.1016/j.nanoso.2024.101320","url":null,"abstract":"L., a medicinal herb rich in secondary metabolites, serves as a sustainable source for synthesizing silver nanoparticles (AgNPs). This study explores the eco-friendly production of AgNPs using aqueous leaf extract from and evaluates their biomedical applications. Characterization techniques including UV-Visible spectroscopy, FT-IR, SEM, TEM, and XRD confirm the spherical shape and FCC structure of the AgNPs, with a mean size of ∼11 nm and a surface charge of −24.4 mV. Biologically, the AgNPs exhibit potent antibacterial activity against both Gram positive and Gram negative bacteria, with dosage-dependent inhibition zones. AgNPs exhibited zone of inhibition comparable to those of standard antibiotic, penicillin, against Gram positive bacteria ( 22.09 mm and 23.72 mm) and Gram negative bacteria (, 13.82 mm and , 14.81 mm). They demonstrate cytotoxicity against NIH 3T3 and MCF-7 cells, with IC of 23.46 μg mL and 19.15 μg mL in cytotoxicity and anticancer assays, respectively. Notably, fragmentation assays reveal smear formation, indicating potential for inducing apoptosis. The synthesized AgNPs from exhibit spherical morphology, moderate stability, and significant antibacterial and anticancer properties, suggesting their potential as versatile biomedical agents.","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"140 1","pages":""},"PeriodicalIF":5.45,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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