Suicide and Life-Threatening Behavior最新文献_第5页

Heightened vigilance and its associations with suicidal ideation and suicide attempt among 285 Korean transgender and nonbinary adults: Effect modification by connectedness to the LGBTQ+ community. 提高警惕及其与 285 名韩国变性和非二元成人的自杀意念和自杀企图之间的关联：通过与 LGBTQ+ 社区的联系来调节效果。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-06-18 DOI: 10.1111/sltb.13104

Sungsub Choo, Ranyeong Kim, Hyemin Lee, Yun-Jung Eom, Horim Yi, Rockli Kim, David R Williams, Seung-Sup Kim

{"title":"Heightened vigilance and its associations with suicidal ideation and suicide attempt among 285 Korean transgender and nonbinary adults: Effect modification by connectedness to the LGBTQ+ community.","authors":"Sungsub Choo, Ranyeong Kim, Hyemin Lee, Yun-Jung Eom, Horim Yi, Rockli Kim, David R Williams, Seung-Sup Kim","doi":"10.1111/sltb.13104","DOIUrl":"10.1111/sltb.13104","url":null,"abstract":"Introduction: Anti-transgender stigma presents threats of discrimination to transgender and nonbinary (TGNB) individuals, prompting them to stay vigilant. Using a longitudinal data of 285 South Korean TGNB adults, we examined vigilance and its associations with suicidal ideation and suicide attempt and explored the protective role of connectedness to the lesbian, gay, bisexual, transgender, and queer (LGBTQ+) community.Methods: Data were collected in October 2021 (baseline) and October 2022 (follow-up). Vigilance was measured using the 4-item Heightened Vigilance Scale at baseline. At follow-up, 12-month suicidal ideation and suicide attempt, and connectedness to the LGBTQ+ community were measured.Results: Having heightened levels of vigilance was associated with increased prevalence of suicidal ideation (Prevalence Ratio [PR]: 1.33, 95% Confidence Interval [CI]: 1.09-1.62) and suicide attempt (PR: 2.18, 95% CI: 1.23-3.86), after adjusting for covariates including anti-transgender discrimination experiences and lifetime suicidality at baseline. When stratified by connectedness to the LGBTQ+ community, the associations between vigilance and suicidality remained statistically significant among those with low connectedness whereas no statistically significant association was observed among those with high connectedness.Conclusion: The study provides empirical evidence for policies and interventions that ensure safety of TGNB individuals from discrimination and promote connectedness to the LGBTQ+ community to reduce the suicide risk among TGNB individuals.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"993-1005"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the predictive utility of suicidal ideation characteristics in relation to real-time monitoring of suicidal ideation and suicide attempts at follow-up. 研究自杀意念特征与实时监测自杀意念和自杀未遂随访的相关性。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-06-18 DOI: 10.1111/sltb.13103

Megan L Rogers, Melanie L Bozzay, Christopher D Hughes, Heather T Schatten, Michael F Armey

{"title":"Examining the predictive utility of suicidal ideation characteristics in relation to real-time monitoring of suicidal ideation and suicide attempts at follow-up.","authors":"Megan L Rogers, Melanie L Bozzay, Christopher D Hughes, Heather T Schatten, Michael F Armey","doi":"10.1111/sltb.13103","DOIUrl":"10.1111/sltb.13103","url":null,"abstract":"Introduction: Several characteristics of suicidal ideation, including frequency, duration, perceived controllability, and intensity, have been identified. The present study examined whether these characteristics of baseline suicidal ideation uniquely predicted (1) the severity, variability, and frequency of suicidal ideation assessed through real-time monitoring; and (2) suicide attempts at 3-week and 6-month follow-up among recently discharged psychiatric inpatients.Methods: A sample of 249 adults (Mage = 40.43, 55.1% female, 91.4% White) completed a baseline assessment of their suicidal ideation characteristics during psychiatric hospitalization, five daily ecological momentary assessments (EMA) for 21 days following discharge, and follow-up assessments of suicide-related outcomes at 3-week and 6-month follow-up.Results: Perceived controllability of suicidal thoughts was uniquely associated with the variability of EMA-assessed suicidal ideation and the presence of suicide attempts at 3-week, but not 6-month follow-up. No other characteristic of baseline suicidal ideation was uniquely associated with EMA-assessed suicidal ideation or the presence of suicide attempts at follow-up.Conclusions: Given links between the perceived controllability of suicidal ideation and (1) momentary variability of suicidal ideation and (2) suicide attempts over the subsequent 3 weeks, perceived controllability of suicidal thinking may be a useful marker of short-term risk that may be malleable to clinical intervention.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"982-992"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceived burdensomeness and thwarted belongingness as mediators of the relation between anxiety and suicidal ideation among adolescents. 感知到的负担和受挫的归属感是青少年焦虑与自杀意念之间关系的中介。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-05-22 DOI: 10.1111/sltb.13094

Lauren Seibel, Katherine M Harris, Roberto López, Jennifer Wolff, Anthony Spirito, Christianne Esposito-Smythers

{"title":"Perceived burdensomeness and thwarted belongingness as mediators of the relation between anxiety and suicidal ideation among adolescents.","authors":"Lauren Seibel, Katherine M Harris, Roberto López, Jennifer Wolff, Anthony Spirito, Christianne Esposito-Smythers","doi":"10.1111/sltb.13094","DOIUrl":"10.1111/sltb.13094","url":null,"abstract":"Introduction: Anxiety and suicidal ideation have been shown to be positively related in adolescents. However, less is known about the strength of this association across different types of anxiety or the mechanisms through which this relation exists. Joiner's interpersonal theory of suicide suggests that thwarted belongingness (TB) and perceived burdensomeness (PB) lead to suicidal ideation; these constructs may explain a pathway through which anxiety and suicidal ideation are related. It was hypothesized that TB would mediate the relation between social anxiety disorder (SAD) symptoms and suicidal ideation, and PB would mediate the relation between generalized anxiety disorder (GAD) symptoms and suicidal ideation.Methods: These longitudinal mediation models were assessed using data collected from 147 depressed adolescents, who were recently hospitalized for suicidal ideation or behavior, enrolled in a randomized controlled trial (RCT).Results: Consistent with study hypotheses, PB mediated the relation between GAD symptoms and suicidal ideation severity. However, TB did not mediate the relation between SAD symptoms and suicidal ideation severity.Conclusion: These results suggest that screening for and addressing PB among youth with GAD may help reduce risk for suicidal behavior.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"914-924"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141082688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A longitudinal study of self-injurious thoughts and behaviors transitions and help-seeking intentions among young adults. 一项关于青少年自残想法和行为过渡以及求助意向的纵向研究。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-06-27 DOI: 10.1111/sltb.13109

Juan Wang, Meng Han, Yingjun Xi, Xiaoxiao He, Yi Feng, Runsen Chen

{"title":"A longitudinal study of self-injurious thoughts and behaviors transitions and help-seeking intentions among young adults.","authors":"Juan Wang, Meng Han, Yingjun Xi, Xiaoxiao He, Yi Feng, Runsen Chen","doi":"10.1111/sltb.13109","DOIUrl":"10.1111/sltb.13109","url":null,"abstract":"Purpose: Engagement in self-injurious thoughts and behaviors (SITBs) is associated with low help-seeking intentions. Nevertheless, prior research has primarily relied on cross-sectional data, leaving uncertainties about the longitudinal dynamics between SITBs and help-seeking intentions. This study aims to investigate the longitudinal relationship between SITBs and help-seeking intentions for them.Method: A one-year interval follow-up investigation was conducted among 1788 Chinese students (71.5% girls, Mage = 19.5). Changes in help-seeking intentions were initially analyzed among four SITBs transition groups. Subsequently, a cross-lagged model was employed to explore the possible bidirectional associations.Results: 232 participants (12.90%) experienced changes in SITBs, while 65 participants (3.60%) exhibited sustained SITBs between two measurement time points. Changes in help-seeking intentions varied across SITBs transition groups. Participants whose SITBs faded 1 year later showed a significant increase in help-seeking intentions, whereas those who experienced newly developed SITBs across two measurement time points demonstrated a significant decline. The cross-lagged analysis revealed that help-seeking intentions negatively predicted the subsequent risk of experiencing SITBs.Conclusions: Greater help-seeking intentions predicted decreased SITBs 1 year later. Changes in help-seeking intentions serve as a valuable indicator for distinguishing between different types of SITBs transition. These findings underscore the importance of implementing prevention and intervention strategies targeted at enhancing help-seeking intentions to reduce SITBs.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"1053-1062"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceived responsiveness in suicidal ideation: An experience sampling study in psychiatric patients. 自杀意念中的感知反应能力：精神病患者的经验取样研究。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-06-01 DOI: 10.1111/sltb.13095

Laura Sels, Stephanie A Homan, Harry T Reis, Andrea B Horn, Jordan Revol, Urte Scholz, Tobias Kowatsch, Birgit Kleim

{"title":"Perceived responsiveness in suicidal ideation: An experience sampling study in psychiatric patients.","authors":"Laura Sels, Stephanie A Homan, Harry T Reis, Andrea B Horn, Jordan Revol, Urte Scholz, Tobias Kowatsch, Birgit Kleim","doi":"10.1111/sltb.13095","DOIUrl":"10.1111/sltb.13095","url":null,"abstract":"Introduction: Perceived responsiveness, or the extent to which one feels understood, validated and cared for by close others, plays a crucial role in people's well-being. Can this interpersonal process also protect people at risk? We assessed whether fluctuations in suicidal ideation were associated with fluctuations in the degree of perceived responsiveness that psychiatric patients (admitted in the context of suicide or indicating suicidal ideation) experienced in daily interactions immediately after discharge.Methods: Fifty-seven patients reported on suicidal ideation (5 times a day) and perceived responsiveness (daily) for four consecutive weeks. The effects of established risk factors-thwarted belongingness, perceived burdensomeness, and hopelessness-were assessed as well.Results: The more patients felt that close others had been responsive to them, the less suicidal ideation they reported. At low levels of thwarted belongingness, perceived burdensomeness, or hopelessness, perceived responsiveness seemed to play a protective role, negatively co-occurring with suicidal ideation. When thwarted belongingness, perceived burdensomeness, and hopelessness were high, perceived responsiveness did not have an effect.Conclusion: Perceived responsiveness could be a protective factor for suicidal ideation for people at risk only when they are experiencing low levels of negative perceptions. When experiencing highly negative perceptions, however, perceived responsiveness seems to matter less.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"925-933"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141186913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining heterogeneity in the affect-regulating function of suicidal ideation: Person-specific analyses in male inpatients with depression. 研究自杀意念的情感调节功能的异质性：对男性抑郁症住院患者进行个体分析。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-07-18 DOI: 10.1111/sltb.13117

Nina Hallensleben, Jannis Kraiss, Heide Glaesmer, Thomas Forkmann, Lena Spangenberg

{"title":"Examining heterogeneity in the affect-regulating function of suicidal ideation: Person-specific analyses in male inpatients with depression.","authors":"Nina Hallensleben, Jannis Kraiss, Heide Glaesmer, Thomas Forkmann, Lena Spangenberg","doi":"10.1111/sltb.13117","DOIUrl":"10.1111/sltb.13117","url":null,"abstract":"Introduction: Men have an increased risk to die by suicide compared to women but are underrepresented in suicide research. To improve individual risk prediction for suicide-related thoughts and behaviors (STBs), risk factors are increasingly being studied at an individual level. The possible affect-regulatory function of suicidal ideation has hardly been investigated ideographically and has not yet been tested in a male sample.Methods: We investigated the bidirectional associations between suicidal ideation and negative and positive affect in a sample of n = 21 male inpatients with unipolar depression and a history of suicidal ideation both at the group level and at the individual level. Participants underwent an intensive ecological momentary assessment for 6 days with 10 data points per day.Results: We found no evidence for an affect-regulatory function of suicidal ideation at the group level, neither for effects of affect on subsequent suicidal ideation (antecedent affect-regulatory hypothesis) nor for effects of suicidal ideation on subsequent affect (consequence affect-regulatory hypothesis). Person-specific analyses revealed substantial variability in strength and direction of the considered associations, especially for the associations representing the antecedent hypothesis.Conclusion: The demonstrated between-person heterogeneity points to the necessity to individualize the investigation of risk factors to enhance prediction and prevention of STBs.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"1123-1132"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141634900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suicidal thoughts and behaviors among gender and sexual minorities: Adults ages 18-24 show highest rates of past month suicidal thoughts. 性别和性少数群体中的自杀想法和行为：18-24 岁的成年人上个月有自杀念头的比例最高。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-05-21 DOI: 10.1111/sltb.13093

M E Manges, C Bryan, A Bryan, C R Bauder, H M Wastler

{"title":"Suicidal thoughts and behaviors among gender and sexual minorities: Adults ages 18-24 show highest rates of past month suicidal thoughts.","authors":"M E Manges, C Bryan, A Bryan, C R Bauder, H M Wastler","doi":"10.1111/sltb.13093","DOIUrl":"10.1111/sltb.13093","url":null,"abstract":"Introduction: Sexual and gender minority (SGM) people are at increased risk for suicidal thoughts and behaviors relative to their cisgender heterosexual peers. However, most research in this area has focused on youth, limiting our understanding of suicide risk among SGM adults.Methods: To address this gap in the literature, the present study examined suicidal thoughts and behaviors among SGM adults across different age groups using a sample of 10,620 US adults.Results: Consistent with the literature on youth, SGM adults showed higher rates of suicidal thoughts and behaviors than cisgender heterosexual adults. When examining prevalence rates across various age groups, young adults (18-24) showed greater lifetime and past month suicidal thoughts and behaviors relative to adults ages 45+. Adults ages 18-24 also showed greater past month suicidal ideation than adults ages 25-44; however, there were no group differences in lifetime suicidal thoughts and behaviors and past month suicidal behavior between adults ages 18-24 and 25-44.Conclusions: Although suicidal thoughts and behaviors are most common among young SGM adults, other age groups do still show concerning rates of suicidal thoughts and behaviors, suggesting that this risk might extend to later years of life. Additional resources for SGM adults that are not only tailored toward youth and young adults are warranted.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"904-913"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Communicating the science of suicide prevention: A call to action for psychologists. 传播预防自杀的科学知识：呼吁心理学家行动起来。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-07-10 DOI: 10.1111/sltb.13114

Allison E Bond, Taylor R Rodriguez, Shelby L Bandel, Jessica L Hamilton, Simone I Boyd, Kathryn Gordon, Michael D Anestis

{"title":"Communicating the science of suicide prevention: A call to action for psychologists.","authors":"Allison E Bond, Taylor R Rodriguez, Shelby L Bandel, Jessica L Hamilton, Simone I Boyd, Kathryn Gordon, Michael D Anestis","doi":"10.1111/sltb.13114","DOIUrl":"10.1111/sltb.13114","url":null,"abstract":"Introduction: Suicide is a major public health concern within the United States, and prevention efforts are essential for decreasing the suicide rate. Researchers and clinicians have knowledge and effective treatments for preventing suicide; however, their impact is limited to those with access to services. Science Communication (SciComm) is an effective tool that can be integrated into the field of suicide prevention and can bridge the gap between scientific findings and the general population. SciComm can help disseminate evidence-based strategies for suicide prevention, dispel misinformation on suicide, and normalize help-seeking.Purpose: In this article, we propose specific, tangible ways that SciComm can be integrated into graduate school programs, mentorship, career advancement requirements and can help enact systemic change within the field of suicide prevention. Additionally, we discuss why it is important that the field of suicide prevention, specifically, adopts a SciComm framework. Embracing SciComm can help the field of suicide prevention to have a broader impact and can help to reduce rates of suicide.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"1092-1100"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Culturally tailoring a secondary suicide prevention intervention for American Indian and Alaska Native people in substance use treatment. 针对接受药物使用治疗的美国印第安人和阿拉斯加原住民，从文化角度制定二级自杀预防干预措施。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-06-28 DOI: 10.1111/sltb.13098

Kelley J Jansen, Adam Livengood, Richard Ries, Katherine Anne Comtois, Dustin M Bergerson, Juli Skinner, Jennifer L Shaw

{"title":"Culturally tailoring a secondary suicide prevention intervention for American Indian and Alaska Native people in substance use treatment.","authors":"Kelley J Jansen, Adam Livengood, Richard Ries, Katherine Anne Comtois, Dustin M Bergerson, Juli Skinner, Jennifer L Shaw","doi":"10.1111/sltb.13098","DOIUrl":"10.1111/sltb.13098","url":null,"abstract":"Background: Substance use treatment programs are ideal places for suicide prevention interventions. People who misuse substances are at elevated risk for suicide compared to the general population. However, most treatment programs do not incorporate suicide prevention, and none have been adapted for American Indian and Alaska Native (AI/AN) people. Preventing Addiction Related Suicide (PARS) is a suicide prevention module developed for use with people in treatment for substance misuse. A previous study demonstrated increased suicide help-seeking among this population.Objective: Culturally adapt PARS for use with AI/AN communities.Methods: We conducted focus groups and interviews with stakeholders in three Tribal health systems. We elicited feedback on PARS content, structure, and implementation. Data were analyzed using constant comparison. Results were used to adapt PARS and member checking was used to refine it.Results: Participants unanimously endorsed using PARS in their health systems. Suggested adaptations included shortening the module, using community-specific information, removing jargon and stigmatizing language, and emphasizing cultural connectedness.Discussion: This community-based, qualitative study adapted the PARS module for use with AI/AN communities. Research is needed to evaluate the clinical effectiveness of the adapted module. If found effective, this would represent the first evidence-based suicide prevention intervention among AI/AN individuals in treatment for substance misuse.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"949-971"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved insomnia is one pathway underlying the anti-suicidal properties of clozapine. 改善失眠是氯氮平具有抗自杀特性的一个途径。

IF 2.7 3区医学

Suicide and Life-Threatening Behavior Pub Date : 2024-12-01 Epub Date: 2024-06-07 DOI: 10.1111/sltb.13099

Ankita Vayalapalli, William V McCall, Joseph P McEvoy, Brian J Miller

{"title":"Improved insomnia is one pathway underlying the anti-suicidal properties of clozapine.","authors":"Ankita Vayalapalli, William V McCall, Joseph P McEvoy, Brian J Miller","doi":"10.1111/sltb.13099","DOIUrl":"10.1111/sltb.13099","url":null,"abstract":"Background: Insomnia is common in schizophrenia and associated with suicide. Clozapine has anti-suicidal properties and beneficial effects on sleep. Whether effects on insomnia mediate the anti-suicidal properties of clozapine remains unclear.Methods: In n = 76 patients from the Clinical Antipsychotic Trials of intervention effectiveness schizophrenia trial using a within-subjects design, we investigated whether improvement in terminal insomnia was associated with improvement in suicidal ideation (SI) after treatment with non-clozapine antipsychotics, and then after treatment with clozapine, using binary logistic regression. Terminal insomnia and SI over the past 2 weeks were assessed before and after both non-clozapine antipsychotic and clozapine treatment with the Calgary Depression Scale for Schizophrenia.Results: There was no association between improved terminal insomnia and resolution of SI after treatment with non-clozapine antipsychotics (OR = 0.2, 95% CI 0.0-9.0, p = 0.41). In the same patients, improved terminal insomnia was associated with resolution of SI after clozapine treatment (OR = 14.6, 95% CI 1.7-129.2, p = 0.02).Conclusions: Improved terminal insomnia is associated with improved SI following clozapine treatment. Findings warrant replication in a larger sample with standard instruments in the assessment of insomnia and suicide, but suggest beneficial effects on sleep as a mediator of the anti-suicidal properties of clozapine. Future mechanistic studies are also needed.","PeriodicalId":39684,"journal":{"name":"Suicide and Life-Threatening Behavior","volume":" ","pages":"972-981"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0