Communicative and Integrative Biology最新文献_第9页

Why are nematodes so successful extremophiles? 为什么线虫是如此成功的极端微生物?

Communicative and Integrative Biology Pub Date : 2021-02-19 DOI: 10.1080/19420889.2021.1884343

Amir Sapir

引用次数: 5

Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands. 内体Rab gtpase调节果蝇幼虫唾液腺分泌颗粒的成熟。

Communicative and Integrative Biology Pub Date : 2021-02-09 DOI: 10.1080/19420889.2021.1874663

Cheng-I Jonathan Ma, Julie A Brill

{"title":"Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands.","authors":"Cheng-I Jonathan Ma, Julie A Brill","doi":"10.1080/19420889.2021.1874663","DOIUrl":"https://doi.org/10.1080/19420889.2021.1874663","url":null,"abstract":"Secretory granules (SGs) are organelles responsible for regulated exocytosis of biologically active molecules in professional secretory cells. Maturation of SGs is a crucial process in which cargoes of SGs are processed and activated, allowing them to exert their function upon secretion. Nonetheless, the intracellular trafficking pathways required for SG maturation are not well defined. We recently performed an RNA interference (RNAi) screen in Drosophila larval salivary glands to identify trafficking components needed for SG maturation. From the screen, we identified several Rab GTPases (Rabs) that affect SG maturation. Expression of constitutively active (CA) and dominant-negative (DN) forms narrowed down the Rabs important for this process to Rab5, Rab9 and Rab11. However, none of these Rabs localizes to the limiting membrane of SGs. In contrast, examination of endogenously YFP-tagged Rabs (YRabs) in larval salivary glands revealed that YRab1 and YRab6 localize to the limiting membrane of immature SGs (iSGs) and SGs. These findings provide new insights into how Rab GTPases contribute to the process of SG maturation.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"2021-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1874663","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25402446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Tissue adhesion between distant plant species in parasitism and grafting. 远缘植物种间寄生和嫁接的组织黏附。

Communicative and Integrative Biology Pub Date : 2021-01-28 DOI: 10.1080/19420889.2021.1877016

Koji Okayasu, Koh Aoki, Ken-Ichi Kurotani, Michitaka Notaguchi

引用次数: 2

Effects of spatial confinement on migratory properties of Dictyostelium discoideum cells. 空间限制对盘状盘柱体细胞迁移特性的影响。

Communicative and Integrative Biology Pub Date : 2021-01-28 DOI: 10.1080/19420889.2021.1872917

Yuri Belotti, David McGloin, Cornelis J Weijer

{"title":"Effects of spatial confinement on migratory properties of Dictyostelium discoideum cells.","authors":"Yuri Belotti, David McGloin, Cornelis J Weijer","doi":"10.1080/19420889.2021.1872917","DOIUrl":"https://doi.org/10.1080/19420889.2021.1872917","url":null,"abstract":"Migratory environments of various eukaryotic cells, such as amoeba, leukocytes and cancer cells, typically involve spatial confinement. Numerous studies have recently emerged, aimed to develop experimental platforms that better recapitulate the characteristics of the cellular microenvironment. Using microfluidic technologies, we show that increasing confinement of Dictyostelium discoideum cells into narrower micro-channels resulted in a significant change in the mode of migration and associated arrangement of the actomyosin cytoskeleton. We observed that cells tended to migrate at constant speed, the magnitude of which was dependent on the size of the channels, as was the locomotory strategy adopted by each cell. Two different migration modes were observed, pseudopod-based and bleb-based migration, with bleb based migration being more frequent with increasing confinement and leading to slower migration. Beside the migration mode, we found that the major determinants of cell speed are its protrusion rate, the amount of F-actin at its leading edge and the number of actin foci. Our results highlighted the impact of the microenvironments on cell behavior. Furthermore, we developed a novel quantitative movement analysis platform for mono-dimensional cell migration that allows for standardization and simplification of the experimental conditions and aids investigation of the complex and dynamic processes occurring at the single-cell level.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"5-14"},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1872917","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25343671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Adhesion stimulates Scar/WAVE phosphorylation in mammalian cells. 粘附刺激哺乳动物细胞的Scar/WAVE磷酸化。

Communicative and Integrative Biology Pub Date : 2020-12-28 DOI: 10.1080/19420889.2020.1855854

Shashi Prakash Singh, Robert H Insall

引用次数: 5

Interoception the foundation for: mind's sensing of 'self,' physiological responses, cognitive discrimination and dysregulation. 内感受是心智感知“自我”、生理反应、认知歧视和失调的基础。

Communicative and Integrative Biology Pub Date : 2020-12-10 DOI: 10.1080/19420889.2020.1846922

Pollard-Wright Holly

{"title":"Interoception the foundation for: mind's sensing of 'self,' physiological responses, cognitive discrimination and dysregulation.","authors":"Pollard-Wright Holly","doi":"10.1080/19420889.2020.1846922","DOIUrl":"10.1080/19420889.2020.1846922","url":null,"abstract":"This article presents a theory of mind whereby interoception (i.e., a sense of signals originating from the body) provides a transdisciplinary framework in which theories from diverse fields may be conformed to ideas from other areas of science. Through a science of interoception, the mind itself investigates the mind and thus can explore how the universe and consciousness came about and understand how interoceptive processing is shaped by experience. Interoception provides a metastable network that enables individuals to compute the significance of stimuli as physiological changes in its complex global context. Both sensory and much cognitive discrimination and integration are affected by the flow of interoceptive information that acts as cues whereby unconscious events may be correlated with conscious events and the reportable content of mental life. Heightened interoceptive sensitivity and individuals who show augmented interoceptive sensitivity are susceptible to a wide range of neuropsychiatric as well as general medical conditions. Physiological responses can be measured and interoceptive awareness cultivated to generate well-being and stress resilience in the treatment of emotional dysregulation and interoceptive abnormalities.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"198-213"},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1846922","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38734669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution. 为什么性不是可有可无的？干细胞竞争、再生能力丧失和癌细胞在后生动物进化中的作用。

Communicative and Integrative Biology Pub Date : 2020-12-10 DOI: 10.1080/19420889.2020.1838809

Chris Fields, Michael Levin

{"title":"Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution.","authors":"Chris Fields, Michael Levin","doi":"10.1080/19420889.2020.1838809","DOIUrl":"10.1080/19420889.2020.1838809","url":null,"abstract":"Animals that can reproduce vegetatively by fission or budding and also sexually via specialized gametes are found in all five primary animal lineages (Bilateria, Cnidaria, Ctenophora, Placozoa, Porifera). Many bilaterian lineages, including roundworms, insects, and most chordates, have lost the capability of vegetative reproduction and are obligately gametic. We suggest a developmental explanation for this evolutionary phenomenon: obligate gametic reproduction is the result of germline stem cells winning a winner-take-all competition with non-germline stem cells for control of reproduction and hence lineage survival. We develop this suggestion by extending Hamilton's rule, which factors the relatedness between parties into the cost/benefit analysis that underpins cooperative behaviors, to include similarity of cellular state. We show how coercive or deceptive cell-cell signaling can be used to make costly cooperative behaviors appear less costly to the cooperating party. We then show how competition between stem-cell lineages can render an ancestral combination of vegetative reproduction with facultative sex unstable, with one or the other process driven to extinction. The increased susceptibility to cancer observed in obligately-sexual lineages is, we suggest, a side-effect of deceptive signaling that is exacerbated by the loss of whole-body regenerative abilities. We suggest a variety of experimental approaches for testing our predictions.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"170-183"},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38786424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant, highly diverse protists in the abyssal Pacific: vulnerability to impacts from seabed mining and potential for recovery. 太平洋深海中巨大的、高度多样化的原生生物:易受海底采矿的影响和恢复的潜力。

Communicative and Integrative Biology Pub Date : 2020-11-25 DOI: 10.1080/19420889.2020.1843818

Andrew J Gooday, Jennifer M Durden, Craig R Smith

{"title":"Giant, highly diverse protists in the abyssal Pacific: vulnerability to impacts from seabed mining and potential for recovery.","authors":"Andrew J Gooday, Jennifer M Durden, Craig R Smith","doi":"10.1080/19420889.2020.1843818","DOIUrl":"https://doi.org/10.1080/19420889.2020.1843818","url":null,"abstract":"Xenophyophores, giant deep-sea agglutinated foraminifera, dominate the benthic megafauna in the eastern equatorial Pacific Clarion-Clipperton Zone. This abyssal (>4000 m depth) region hosts major deposits of polymetallic nodules targeted for future seabed mining, an activity that would destroy these highly diverse and delicate protists, particularly those living on the nodules themselves. Since the cell occupies only a small proportion of their test volume, xenophyophores may make a fairly modest contribution to benthic biomass and carbon cycling. Nevertheless, xenophyophore tests can passively enhance particle deposition, concentrate food, and provide habitat structure utilized by diverse organisms. Their destruction could therefore influence the recovery of benthic communities. Species requiring nodule substrates will likely not recover, since nodules take millions of years to form. However, xenophyophores can grow quickly and colonize extensive volcanic ash deposits within years, suggesting that sediment-dwelling species could be among the first large immobile organisms to reappear in mining-impacted areas.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"189-197"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1843818","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38716836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Endosymbiosis morphological reorganization during metamorphosis diverges in weevils. 象鼻虫变态过程中的内共生形态重组存在分歧。

Communicative and Integrative Biology Pub Date : 2020-11-02 DOI: 10.1080/19420889.2020.1840707

Justin Maire, Bessem Chouaia, Anna Zaidman-Rémy, Abdelaziz Heddi

{"title":"Endosymbiosis morphological reorganization during metamorphosis diverges in weevils.","authors":"Justin Maire, Bessem Chouaia, Anna Zaidman-Rémy, Abdelaziz Heddi","doi":"10.1080/19420889.2020.1840707","DOIUrl":"https://doi.org/10.1080/19420889.2020.1840707","url":null,"abstract":"Virtually all animals associate with beneficial symbiotic bacteria. Whether and how these associations are modulated across a host's lifecycle is an important question in disentangling animal-bacteria interactions. We recently reported a case of complete morphological reorganization of symbiosis during metamorphosis of the cereal weevil, Sitophilus oryzae. In this model, the bacteriome, a specialized organ that houses the intracellular bacterium Sodalis pierantonius, undergoes a two-phase remodeling program synchronously driven by host and endosymbiont, resulting in a localization shift and the formation of multiple new bacteriomes. Here, we provide comparative data in a closely-related coleopteran, the red palm weevil Rhynchophorus ferrugineus, which is associated with the ancestral endosymbiont Nardonella. Using cell imaging experiments, we show that the red pal weevil bacteriome remains unchanged during metamorphosis, hence contrasting with what we reported in the cereal weevil S. oryzae. These findings highlight the complexity and divergence of host-symbiont interactions and their intertwining with host development, even in closely-related species. Abbreviations: DAPI: 4',6-diamidino-2-phenylindole; FISH: Fluorescence in situ hybridization; T3SS: Type III secretion system.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"184-188"},"PeriodicalIF":0.0,"publicationDate":"2020-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1840707","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38605739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Evaluation of the sensitivity and synergistic effect of Trichoderma reesei and mancozeb to inhibit under in vitro conditions the growth of Fusarium oxysporum. 里氏木霉与代森锰锌对尖孢镰刀菌体外抑制的敏感性及协同效应评价。

Communicative and Integrative Biology Pub Date : 2020-10-20 DOI: 10.1080/19420889.2020.1829267

María Fernanda Gonzalez, Freddy Magdama, Luis Galarza, Daynet Sosa, Christian Romero

{"title":"Evaluation of the sensitivity and synergistic effect of Trichoderma reesei and mancozeb to inhibit under in vitro conditions the growth of Fusarium oxysporum.","authors":"María Fernanda Gonzalez, Freddy Magdama, Luis Galarza, Daynet Sosa, Christian Romero","doi":"10.1080/19420889.2020.1829267","DOIUrl":"https://doi.org/10.1080/19420889.2020.1829267","url":null,"abstract":"Trichoderma is a saprophytic, soil-borne fungus with a worldwide distribution that has been extensively studied due to their capacity to synthesize secondary metabolites with antimicrobial activity, parasitize other fungi and directly interact with plant roots, inducing resistance to disease and tolerance to abiotic stresses. Fusarium wilt caused by the soil-inhabiting fungus Fusarium oxysporum is considered one of the most important diseases that affect banana cultivars. Currently, more environmentally friendly alternatives to control this disease are being proposed, these strategies include the application of low doses of synthetic fungicides and the use of biocontrol agents such as Trichoderma or Xylaria. Thus, this study aimed to evaluate under in vitro conditions the synergistic effect of the biological control agent T. reesei C2A combined with low doses of mancozeb to inhibit the mycelial growth of F. oxysporum F1. To perform the synergistic essays, 0.1 mg/mL of mancozeb was suspended in PDA plates, then plugs of T. ressei C2A were placed at the center of the Petri dishes, the plates were incubated for 7 days at 28°C. Results showed that the mycoparasitic capacity of the biocontrol strain to inhibit the mycelial growth of F. oxysporum F1 was enhanced approximately 36% compared to the control plates. Although these results are promising, future studies under greenhouse and field conditions are necessary to corroborate the effectiveness of this approach.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"160-169"},"PeriodicalIF":0.0,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1829267","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38569379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8