Communicative and Integrative Biology最新文献_第9页

Systemic effects of oxytocin on male sexual activity via the spinal ejaculation generator in rats. 通过大鼠脊髓射精发生器，催产素对雄性性活动的全身影响。

Communicative and Integrative Biology Pub Date : 2021-03-29 DOI: 10.1080/19420889.2021.1902056

Takumi Oti, Tatsuya Sakamoto, Hirotaka Sakamoto

{"title":"Systemic effects of oxytocin on male sexual activity via the spinal ejaculation generator in rats.","authors":"Takumi Oti, Tatsuya Sakamoto, Hirotaka Sakamoto","doi":"10.1080/19420889.2021.1902056","DOIUrl":"https://doi.org/10.1080/19420889.2021.1902056","url":null,"abstract":"Oxytocin is produced in the hypothalamus and stimulates uterine contraction and milk ejection. While many people consider oxytocin to be a female hormone, it is reported that, in men, the plasma oxytocin level increases markedly after ejaculation. However, this aspect of oxytocin physiology is poorly understood. The spinal ejaculation generator (SEG), which expresses the neuropeptide, gastrin-releasing peptide (GRP), can trigger ejaculation in rats. Therefore, we focused on systemic effects of oxytocin on the GRP/SEG neuron system in the lumbar spinal cord controlling sexual activity in male rats. We found that systemic administration of oxytocin significantly shortened the latency to the first mount, intromission and ejaculation during male copulatory behavior. In addition, the local oxytocin level in the lumbar cord was significantly higher in males than in females. Histological analysis showed that oxytocin-binding is apparent in spinal GRP/SEG neurons. We therefore conclude that oxytocin influences male sexual activity via the SEG.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"55-60"},"PeriodicalIF":0.0,"publicationDate":"2021-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1902056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25568866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Application of time-series regularity metrics to ion flux data from a population of pollen tubes. 时间序列规则度量在花粉管种群离子通量数据中的应用。

Communicative and Integrative Biology Pub Date : 2021-03-19 DOI: 10.1080/19420889.2021.1899574

Mariusz A Pietruszka

引用次数: 4

On the theory of mental representation block. a novel perspective on learning and behavior. 论心理表征障碍理论。学习和行为的新视角。

Communicative and Integrative Biology Pub Date : 2021-03-12 DOI: 10.1080/19420889.2021.1898752

Tobore Onojighofia Tobore

{"title":"On the theory of mental representation block. a novel perspective on learning and behavior.","authors":"Tobore Onojighofia Tobore","doi":"10.1080/19420889.2021.1898752","DOIUrl":"10.1080/19420889.2021.1898752","url":null,"abstract":"Understanding the mechanisms behind memory, learning, and behavior is crucial to human development and significant research has been done in this area. Classical and operant conditioning and other theories of learning have elucidated different mechanisms of learning and how it modulates behavior. Even with advances in this area, questions remain on how to unlearn faulty ideas or extinguish maladaptive behaviors. In this paper, a novel theory to improve our understanding of this area is proposed. The theory proposes that as a consequence of the brain's energy efficiency evolutionary adaptations, all learning following memory consolidation, reconsolidation, and repeated reinforcements or strengthening over time, results in a phenomenon called mental representation block. The implications of this block on learning and behavior are significant and broad and include cognitive biases, belief in a creator or God, close-mindedness, dogmatism, physician misdiagnosis, racism, homophobia, and transphobia, susceptibility to deception and indoctrination, hate and love, artificial intelligence and creativity.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"41-50"},"PeriodicalIF":0.0,"publicationDate":"2021-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1898752","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25540354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bat target tracking strategies for prey interception. 蝙蝠目标跟踪策略的猎物拦截。

Communicative and Integrative Biology Pub Date : 2021-03-12 DOI: 10.1080/19420889.2021.1898751

Angeles Salles, Clarice A Diebold, Cynthia F Moss

引用次数: 4

A universal model describing the structure and functions of living systems. 描述生命系统结构和功能的通用模型。

Communicative and Integrative Biology Pub Date : 2021-02-24 DOI: 10.1080/19420889.2021.1887549

Antonis Mistriotis

{"title":"A universal model describing the structure and functions of living systems.","authors":"Antonis Mistriotis","doi":"10.1080/19420889.2021.1887549","DOIUrl":"https://doi.org/10.1080/19420889.2021.1887549","url":null,"abstract":"Can Life be explained based on the fundamental Laws of Nature? This question is central in Science since its answer could unify Physics and Biology and open new routes for Medicine. The present study introduces a clear and well-documented hypothesis addressing the unified description of all living systems. The proposed universal model is based on two established characteristics of Life. First, the concept of Functional Self-similarity (FSS) is introduced. As shown by several authors, all living systems can be classified in a multi-level hierarchy of increasing complexity. Systems in all hierarchical levels are characterized by a small set of the same attributes defining Life. This observation implies the existence of an elementary living system (i.e., a quantum of Life) having all the necessary functionalities of living systems. Secondly, the non-equilibrium nature of living systems implies that they should be able to process information since such a function is required for reducing entropy. Therefore, all living systems necessarily perform logical operations similar to electronic circuits. This conclusion, which is based on the requirement to overcome the constraints of the Second Law of Thermodynamics, indicates a close correspondence between living systems and information processing machines, namely computers. Consequently, important theoretical principles and concepts regarding computer design may also apply in the study of living systems. The above considerations lead to the Hypothesis of a Universal Architecture (UAH).","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"27-36"},"PeriodicalIF":0.0,"publicationDate":"2021-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1887549","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25445401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Why are nematodes so successful extremophiles? 为什么线虫是如此成功的极端微生物?

Communicative and Integrative Biology Pub Date : 2021-02-19 DOI: 10.1080/19420889.2021.1884343

Amir Sapir

引用次数: 5

Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands. 内体Rab gtpase调节果蝇幼虫唾液腺分泌颗粒的成熟。

Communicative and Integrative Biology Pub Date : 2021-02-09 DOI: 10.1080/19420889.2021.1874663

Cheng-I Jonathan Ma, Julie A Brill

{"title":"Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands.","authors":"Cheng-I Jonathan Ma, Julie A Brill","doi":"10.1080/19420889.2021.1874663","DOIUrl":"https://doi.org/10.1080/19420889.2021.1874663","url":null,"abstract":"Secretory granules (SGs) are organelles responsible for regulated exocytosis of biologically active molecules in professional secretory cells. Maturation of SGs is a crucial process in which cargoes of SGs are processed and activated, allowing them to exert their function upon secretion. Nonetheless, the intracellular trafficking pathways required for SG maturation are not well defined. We recently performed an RNA interference (RNAi) screen in Drosophila larval salivary glands to identify trafficking components needed for SG maturation. From the screen, we identified several Rab GTPases (Rabs) that affect SG maturation. Expression of constitutively active (CA) and dominant-negative (DN) forms narrowed down the Rabs important for this process to Rab5, Rab9 and Rab11. However, none of these Rabs localizes to the limiting membrane of SGs. In contrast, examination of endogenously YFP-tagged Rabs (YRabs) in larval salivary glands revealed that YRab1 and YRab6 localize to the limiting membrane of immature SGs (iSGs) and SGs. These findings provide new insights into how Rab GTPases contribute to the process of SG maturation.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"2021-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1874663","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25402446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Tissue adhesion between distant plant species in parasitism and grafting. 远缘植物种间寄生和嫁接的组织黏附。

Communicative and Integrative Biology Pub Date : 2021-01-28 DOI: 10.1080/19420889.2021.1877016

Koji Okayasu, Koh Aoki, Ken-Ichi Kurotani, Michitaka Notaguchi

引用次数: 2

Effects of spatial confinement on migratory properties of Dictyostelium discoideum cells. 空间限制对盘状盘柱体细胞迁移特性的影响。

Communicative and Integrative Biology Pub Date : 2021-01-28 DOI: 10.1080/19420889.2021.1872917

Yuri Belotti, David McGloin, Cornelis J Weijer

{"title":"Effects of spatial confinement on migratory properties of Dictyostelium discoideum cells.","authors":"Yuri Belotti, David McGloin, Cornelis J Weijer","doi":"10.1080/19420889.2021.1872917","DOIUrl":"https://doi.org/10.1080/19420889.2021.1872917","url":null,"abstract":"Migratory environments of various eukaryotic cells, such as amoeba, leukocytes and cancer cells, typically involve spatial confinement. Numerous studies have recently emerged, aimed to develop experimental platforms that better recapitulate the characteristics of the cellular microenvironment. Using microfluidic technologies, we show that increasing confinement of Dictyostelium discoideum cells into narrower micro-channels resulted in a significant change in the mode of migration and associated arrangement of the actomyosin cytoskeleton. We observed that cells tended to migrate at constant speed, the magnitude of which was dependent on the size of the channels, as was the locomotory strategy adopted by each cell. Two different migration modes were observed, pseudopod-based and bleb-based migration, with bleb based migration being more frequent with increasing confinement and leading to slower migration. Beside the migration mode, we found that the major determinants of cell speed are its protrusion rate, the amount of F-actin at its leading edge and the number of actin foci. Our results highlighted the impact of the microenvironments on cell behavior. Furthermore, we developed a novel quantitative movement analysis platform for mono-dimensional cell migration that allows for standardization and simplification of the experimental conditions and aids investigation of the complex and dynamic processes occurring at the single-cell level.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"5-14"},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1872917","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25343671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Adhesion stimulates Scar/WAVE phosphorylation in mammalian cells. 粘附刺激哺乳动物细胞的Scar/WAVE磷酸化。

Communicative and Integrative Biology Pub Date : 2020-12-28 DOI: 10.1080/19420889.2020.1855854

Shashi Prakash Singh, Robert H Insall

引用次数: 5