Communicative and Integrative Biology最新文献_第10页

Interoception the foundation for: mind's sensing of 'self,' physiological responses, cognitive discrimination and dysregulation. 内感受是心智感知“自我”、生理反应、认知歧视和失调的基础。

Communicative and Integrative Biology Pub Date : 2020-12-10 DOI: 10.1080/19420889.2020.1846922

Pollard-Wright Holly

{"title":"Interoception the foundation for: mind's sensing of 'self,' physiological responses, cognitive discrimination and dysregulation.","authors":"Pollard-Wright Holly","doi":"10.1080/19420889.2020.1846922","DOIUrl":"10.1080/19420889.2020.1846922","url":null,"abstract":"This article presents a theory of mind whereby interoception (i.e., a sense of signals originating from the body) provides a transdisciplinary framework in which theories from diverse fields may be conformed to ideas from other areas of science. Through a science of interoception, the mind itself investigates the mind and thus can explore how the universe and consciousness came about and understand how interoceptive processing is shaped by experience. Interoception provides a metastable network that enables individuals to compute the significance of stimuli as physiological changes in its complex global context. Both sensory and much cognitive discrimination and integration are affected by the flow of interoceptive information that acts as cues whereby unconscious events may be correlated with conscious events and the reportable content of mental life. Heightened interoceptive sensitivity and individuals who show augmented interoceptive sensitivity are susceptible to a wide range of neuropsychiatric as well as general medical conditions. Physiological responses can be measured and interoceptive awareness cultivated to generate well-being and stress resilience in the treatment of emotional dysregulation and interoceptive abnormalities.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"198-213"},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1846922","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38734669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution. 为什么性不是可有可无的？干细胞竞争、再生能力丧失和癌细胞在后生动物进化中的作用。

Communicative and Integrative Biology Pub Date : 2020-12-10 DOI: 10.1080/19420889.2020.1838809

Chris Fields, Michael Levin

{"title":"Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution.","authors":"Chris Fields, Michael Levin","doi":"10.1080/19420889.2020.1838809","DOIUrl":"10.1080/19420889.2020.1838809","url":null,"abstract":"Animals that can reproduce vegetatively by fission or budding and also sexually via specialized gametes are found in all five primary animal lineages (Bilateria, Cnidaria, Ctenophora, Placozoa, Porifera). Many bilaterian lineages, including roundworms, insects, and most chordates, have lost the capability of vegetative reproduction and are obligately gametic. We suggest a developmental explanation for this evolutionary phenomenon: obligate gametic reproduction is the result of germline stem cells winning a winner-take-all competition with non-germline stem cells for control of reproduction and hence lineage survival. We develop this suggestion by extending Hamilton's rule, which factors the relatedness between parties into the cost/benefit analysis that underpins cooperative behaviors, to include similarity of cellular state. We show how coercive or deceptive cell-cell signaling can be used to make costly cooperative behaviors appear less costly to the cooperating party. We then show how competition between stem-cell lineages can render an ancestral combination of vegetative reproduction with facultative sex unstable, with one or the other process driven to extinction. The increased susceptibility to cancer observed in obligately-sexual lineages is, we suggest, a side-effect of deceptive signaling that is exacerbated by the loss of whole-body regenerative abilities. We suggest a variety of experimental approaches for testing our predictions.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"170-183"},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38786424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant, highly diverse protists in the abyssal Pacific: vulnerability to impacts from seabed mining and potential for recovery. 太平洋深海中巨大的、高度多样化的原生生物:易受海底采矿的影响和恢复的潜力。

Communicative and Integrative Biology Pub Date : 2020-11-25 DOI: 10.1080/19420889.2020.1843818

Andrew J Gooday, Jennifer M Durden, Craig R Smith

{"title":"Giant, highly diverse protists in the abyssal Pacific: vulnerability to impacts from seabed mining and potential for recovery.","authors":"Andrew J Gooday, Jennifer M Durden, Craig R Smith","doi":"10.1080/19420889.2020.1843818","DOIUrl":"https://doi.org/10.1080/19420889.2020.1843818","url":null,"abstract":"Xenophyophores, giant deep-sea agglutinated foraminifera, dominate the benthic megafauna in the eastern equatorial Pacific Clarion-Clipperton Zone. This abyssal (>4000 m depth) region hosts major deposits of polymetallic nodules targeted for future seabed mining, an activity that would destroy these highly diverse and delicate protists, particularly those living on the nodules themselves. Since the cell occupies only a small proportion of their test volume, xenophyophores may make a fairly modest contribution to benthic biomass and carbon cycling. Nevertheless, xenophyophore tests can passively enhance particle deposition, concentrate food, and provide habitat structure utilized by diverse organisms. Their destruction could therefore influence the recovery of benthic communities. Species requiring nodule substrates will likely not recover, since nodules take millions of years to form. However, xenophyophores can grow quickly and colonize extensive volcanic ash deposits within years, suggesting that sediment-dwelling species could be among the first large immobile organisms to reappear in mining-impacted areas.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"189-197"},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1843818","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38716836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Endosymbiosis morphological reorganization during metamorphosis diverges in weevils. 象鼻虫变态过程中的内共生形态重组存在分歧。

Communicative and Integrative Biology Pub Date : 2020-11-02 DOI: 10.1080/19420889.2020.1840707

Justin Maire, Bessem Chouaia, Anna Zaidman-Rémy, Abdelaziz Heddi

{"title":"Endosymbiosis morphological reorganization during metamorphosis diverges in weevils.","authors":"Justin Maire, Bessem Chouaia, Anna Zaidman-Rémy, Abdelaziz Heddi","doi":"10.1080/19420889.2020.1840707","DOIUrl":"https://doi.org/10.1080/19420889.2020.1840707","url":null,"abstract":"Virtually all animals associate with beneficial symbiotic bacteria. Whether and how these associations are modulated across a host's lifecycle is an important question in disentangling animal-bacteria interactions. We recently reported a case of complete morphological reorganization of symbiosis during metamorphosis of the cereal weevil, Sitophilus oryzae. In this model, the bacteriome, a specialized organ that houses the intracellular bacterium Sodalis pierantonius, undergoes a two-phase remodeling program synchronously driven by host and endosymbiont, resulting in a localization shift and the formation of multiple new bacteriomes. Here, we provide comparative data in a closely-related coleopteran, the red palm weevil Rhynchophorus ferrugineus, which is associated with the ancestral endosymbiont Nardonella. Using cell imaging experiments, we show that the red pal weevil bacteriome remains unchanged during metamorphosis, hence contrasting with what we reported in the cereal weevil S. oryzae. These findings highlight the complexity and divergence of host-symbiont interactions and their intertwining with host development, even in closely-related species. Abbreviations: DAPI: 4',6-diamidino-2-phenylindole; FISH: Fluorescence in situ hybridization; T3SS: Type III secretion system.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"184-188"},"PeriodicalIF":0.0,"publicationDate":"2020-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1840707","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38605739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Evaluation of the sensitivity and synergistic effect of Trichoderma reesei and mancozeb to inhibit under in vitro conditions the growth of Fusarium oxysporum. 里氏木霉与代森锰锌对尖孢镰刀菌体外抑制的敏感性及协同效应评价。

Communicative and Integrative Biology Pub Date : 2020-10-20 DOI: 10.1080/19420889.2020.1829267

María Fernanda Gonzalez, Freddy Magdama, Luis Galarza, Daynet Sosa, Christian Romero

{"title":"Evaluation of the sensitivity and synergistic effect of Trichoderma reesei and mancozeb to inhibit under in vitro conditions the growth of Fusarium oxysporum.","authors":"María Fernanda Gonzalez, Freddy Magdama, Luis Galarza, Daynet Sosa, Christian Romero","doi":"10.1080/19420889.2020.1829267","DOIUrl":"https://doi.org/10.1080/19420889.2020.1829267","url":null,"abstract":"Trichoderma is a saprophytic, soil-borne fungus with a worldwide distribution that has been extensively studied due to their capacity to synthesize secondary metabolites with antimicrobial activity, parasitize other fungi and directly interact with plant roots, inducing resistance to disease and tolerance to abiotic stresses. Fusarium wilt caused by the soil-inhabiting fungus Fusarium oxysporum is considered one of the most important diseases that affect banana cultivars. Currently, more environmentally friendly alternatives to control this disease are being proposed, these strategies include the application of low doses of synthetic fungicides and the use of biocontrol agents such as Trichoderma or Xylaria. Thus, this study aimed to evaluate under in vitro conditions the synergistic effect of the biological control agent T. reesei C2A combined with low doses of mancozeb to inhibit the mycelial growth of F. oxysporum F1. To perform the synergistic essays, 0.1 mg/mL of mancozeb was suspended in PDA plates, then plugs of T. ressei C2A were placed at the center of the Petri dishes, the plates were incubated for 7 days at 28°C. Results showed that the mycoparasitic capacity of the biocontrol strain to inhibit the mycelial growth of F. oxysporum F1 was enhanced approximately 36% compared to the control plates. Although these results are promising, future studies under greenhouse and field conditions are necessary to corroborate the effectiveness of this approach.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"160-169"},"PeriodicalIF":0.0,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1829267","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38569379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

The nonlocal universe. 非定域宇宙。

Communicative and Integrative Biology Pub Date : 2020-10-11 DOI: 10.1080/19420889.2020.1822583

Andrew Lohrey, Bruce Boreham

引用次数: 5

New insights into the limited thermotolerance of anhydrobiotic tardigrades. 对无水缓步动物有限耐热性的新认识。

Communicative and Integrative Biology Pub Date : 2020-09-09 DOI: 10.1080/19420889.2020.1812865

Ricardo Cardoso Neves, Robyn M Stuart, Nadja Møbjerg

{"title":"New insights into the limited thermotolerance of anhydrobiotic tardigrades.","authors":"Ricardo Cardoso Neves, Robyn M Stuart, Nadja Møbjerg","doi":"10.1080/19420889.2020.1812865","DOIUrl":"https://doi.org/10.1080/19420889.2020.1812865","url":null,"abstract":"The recent discovery of an upper limit in the tolerance of an extremotolerant tardigrade to high temperatures is astounding. Although these microinvertebrates are able to endure severe environmental conditions, including desiccation, freezing and high levels of radiation, high temperatures seem to be an Achilles' heel for active tardigrades. Moreover, exposure-time appears to be a limiting factor for the heat stress tolerance of the otherwise highly resilient desiccated (anhydrobiotic) tardigrades. Indeed, the survival rate of desiccated tardigrades exposed to high temperatures for 24 hours is significantly lower than for exposures of only 1 hour. Here, we investigate the effect of 1 week of high temperature exposures on desiccated tardigrades with the aim of elucidating whether exposure-times longer than 24 hours decrease survival even further. From our analyses we estimate a significant decrease in the 50% mortality temperature from 63ºC to 56ºC for Ramazzottius varieornatus exposed to high temperatures in the desiccated tun state for 24 hours and 1 week, respectively. This negative correlation between exposure-time and tolerance to high temperatures probably results from the interference of intracellular temperature with the homeostasis of macromolecules. We hypothesize that high temperatures denature molecules that play a vital role in sustaining and protecting the anhydrobiotic state.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"140-146"},"PeriodicalIF":0.0,"publicationDate":"2020-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1812865","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38451890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Hidden Allee effect in photosynthetic organisms. 光合生物的隐巷效应。

Communicative and Integrative Biology Pub Date : 2020-08-30 DOI: 10.1080/19420889.2020.1800999

Hiroshi Ohkawa, Chiharu Takatsuka, Tomonori Kawano

{"title":"Hidden Allee effect in photosynthetic organisms.","authors":"Hiroshi Ohkawa, Chiharu Takatsuka, Tomonori Kawano","doi":"10.1080/19420889.2020.1800999","DOIUrl":"https://doi.org/10.1080/19420889.2020.1800999","url":null,"abstract":"In ecology and population biology, logistic equation is widely applied for simulating the population of organisms. By combining the logistic model with the low-density effect called Allee effect, several variations of mathematical expressions have been proposed. The upper half of the work was dedicated to establish a novel equation for highly flexible density effect model with Allee threshold. Allee effect has been rarely observed in microorganisms with asexual reproduction despite of theoretical studies. According to the exploitation ecosystem hypotheses, plants are believed to be insensitive to Allee effect. Taken together, knowledge on the existence of low-density effect in photosynthetic microorganisms is required for redefining the ecological theories emphasizing the photosynthetic organisms as the basis for food chains. Therefore, in the lower half of the present article, we report on the possible Allee effect in photo-autotrophic organisms, namely, green paramecia, and cyanobacteria. Optically monitored growth of green paramecia was shown to be regulated by Allee-like weak low-density effect under photo-autotrophic and photo-heterotrophic conditions. Insensitiveness of wild type cyanobacteria (Synechocystis sp. Strain PCC6803) to low-density effect was confirmed, as consistent with our empirical knowledge. In contrast, a mutant line of PCC6803 impaired with a photosynthesis-related pxcA gene was shown to be sensitive to typical Allee's low-density effect (i.e. this line of cells failed to propagate at low cellular density while cells start logarithmic growth at relatively higher inoculating density). This is the first observation that single-gene mutation in an autotrophic organism alters the sensitivity to Allee effect.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"119-127"},"PeriodicalIF":0.0,"publicationDate":"2020-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1800999","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38451888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

GPCR receptor phosphorylation and endocytosis are not necessary to switch polarized growth between internal cues during pheromone response in S. cerevisiae. 在信息素反应过程中，酿酒葡萄球菌的GPCR受体磷酸化和内吞作用对于在内部信号之间切换极化生长并不是必需的。

Communicative and Integrative Biology Pub Date : 2020-08-20 DOI: 10.1080/19420889.2020.1806667

Gustavo Vasen, Paula Dunayevich, Andreas Constantinou, Alejandro Colman-Lerner

{"title":"GPCR receptor phosphorylation and endocytosis are not necessary to switch polarized growth between internal cues during pheromone response in S. cerevisiae.","authors":"Gustavo Vasen, Paula Dunayevich, Andreas Constantinou, Alejandro Colman-Lerner","doi":"10.1080/19420889.2020.1806667","DOIUrl":"10.1080/19420889.2020.1806667","url":null,"abstract":"Chemotactic/chemotropic cells follow accurately the direction of gradients of regulatory molecules. Many G-protein-coupled receptors (GPCR) function as chemoattractant receptors to guide polarized responses. In \"a\" mating type yeast, the GPCR Ste2 senses the α-cell's pheromone. Previously, phosphorylation and trafficking of this receptor have been implicated in the process of gradient sensing, where cells dynamically correct growth. Correction is often necessary since yeast have intrinsic polarity sites that interfere with a correct initial gradient decoding. We have recently showed that when actively dividing (not in G1) yeast are exposed to a uniform pheromone concentration, they initiate a pheromone-induced polarization next to the mother-daughter cytokinesis site. Then, they reorient their growth to the intrinsic polarity site. Here, to study if Ste2 phosphorylation and internalization are involved in this process, we generated receptor variants combining three types of mutated signals for the first time: phosphorylation, ubiquitylation and the NPFX1,2D Sla1-binding motif. We first characterized their effect on endocytosis and found that these processes regulate internalization in a more complex manner than previously shown. Interestingly, we showed that receptor phosphorylation can drive internalization independently of ubiquitylation and the NPFX1,2D motif. When tested in our assays, cells expressing either phosphorylation or endocytosis-deficient receptors were able to switch away from the cytokinesis site to find the intrinsic polarity site as efficiently as their WT counterparts. Thus, we conclude that these processes are not necessary for the reorientation of polarization.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":" ","pages":"128-139"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2020.1806667","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38451889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Emergence of informative higher scales in biological systems: a computational toolkit for optimal prediction and control. 生物系统中信息量更大尺度的出现：优化预测和控制的计算工具包。

Communicative and Integrative Biology Pub Date : 2020-08-15 DOI: 10.1080/19420889.2020.1802914

Erik Hoel, Michael Levin

引用次数: 0