Communicative and Integrative Biology最新文献_第8页

The search for molecular mimicry in proteins carried by extracellular vesicles secreted by cells infected with Plasmodium falciparum. 寻找恶性疟原虫感染细胞分泌的细胞外囊泡所携带蛋白质的分子模拟。

Communicative and Integrative Biology Pub Date : 2021-09-08 eCollection Date: 2021-01-01 DOI: 10.1080/19420889.2021.1972523

Vinicio Armijos-Jaramillo, Andrea Mosquera, Brian Rojas, Eduardo Tejera

{"title":"The search for molecular mimicry in proteins carried by extracellular vesicles secreted by cells infected with Plasmodium falciparum.","authors":"Vinicio Armijos-Jaramillo, Andrea Mosquera, Brian Rojas, Eduardo Tejera","doi":"10.1080/19420889.2021.1972523","DOIUrl":"10.1080/19420889.2021.1972523","url":null,"abstract":"Red blood cells infected with Plasmodium falciparum secrete extracellular vesicles in order to facilitate the survival and infection of human cells. Various researchers have studied the composition of these extracellular vesicles and identified the proteins contained inside. In this work, we used that information to detect potential P. falciparum molecules that could be imitating host proteins. We carried out several searches to detect sequences and structural similarities between the parasite and host. Additionally, the possibility of functional mimicry was explored in line with the potential role that each candidate can perform for the parasite inside the host. Lastly, we determined a set of eight sequences (mainly moonlighting proteins) with a remarkable resemblance to human proteins. Due to the resemblance observed, this study proposes the possibility that certain P. falciparum molecules carried by extracellular vesicles could be imitating human proteins to manipulate the host cell's physiology.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"212-220"},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39439911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cracking the code: a comparative approach to plant communication. 破解密码:植物交流的比较方法。

Communicative and Integrative Biology Pub Date : 2021-08-17 eCollection Date: 2021-01-01 DOI: 10.1080/19420889.2021.1956719

Bianca Bonato, Francesca Peressotti, Silvia Guerra, Qiuran Wang, Umberto Castiello

{"title":"Cracking the code: a comparative approach to plant communication.","authors":"Bianca Bonato, Francesca Peressotti, Silvia Guerra, Qiuran Wang, Umberto Castiello","doi":"10.1080/19420889.2021.1956719","DOIUrl":"https://doi.org/10.1080/19420889.2021.1956719","url":null,"abstract":"The linguistic behavior of humans is usually considered the point of reference for studying the origin and evolution of language. As commonly defined, language is a form of communication between human beings; many have argued that it is unique to humans as there is no apparent equivalent for it in non-human organisms. How language is used as a means of communication is examined in this essay from a biological perspective positing that it is effectively and meaningfully used by non-human organisms and, more specifically, by plants. We set out to draw parallels between some aspects characterizing human language and the chemical communication that occurs between plants. The essay examines the similarities in ways of communicating linked to three properties of language: its combinatorial structure, meaning-making activities and the existence of dialects. In accordance with the findings of researchers who have demonstrated that plants do indeed communicate with one another and with organisms in their environment, the essay concludes with the appeal for an interdisciplinary approach conceptualizing a broader ecological definition of language and a constructive dialogue between the biological sciences and the humanities.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"176-185"},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39344508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Modeling the role of gravitation in metabolic processes. 模拟重力在代谢过程中的作用。

Communicative and Integrative Biology Pub Date : 2021-07-20 eCollection Date: 2021-01-01 DOI: 10.1080/19420889.2021.1914913

Steve Thorne

{"title":"Modeling the role of gravitation in metabolic processes.","authors":"Steve Thorne","doi":"10.1080/19420889.2021.1914913","DOIUrl":"https://doi.org/10.1080/19420889.2021.1914913","url":null,"abstract":"All living organisms are gravitationally bound to earth's surface and spun through three major gravitational potentials at nearly Mach 88. Along this pathway, organisms are subjected to non-isotropic strains that are repetitive in their geometry and their periodicity. Because of the relative smallness of this bias and the slow rate at which such strain accumulates, it typically goes undetected or treated stochastically as a variance from 'best-fit' models and woven into our empirical data. Far from being purely isotropic, equilibrium in systems co-moving with the earth possesses a dynamic component with bias defined by our orbital motion. Interestingly, biologists identify a similar bias in living organisms expressed in the chiral nature of key metabolic molecules and the periodicities of their metabolic cycles. Biologists have also identified a mean mass-specific metabolic rate that correlates well with the daily change in gravitational potential energy experienced by an organism. The evidence is only correlative, but it raises the intriguing question of whether 3 billion years of exposure to gravitational strain cycles might have led to a metabolic strategy that coupled to them. Because the subject of gravity has been omitted from most biology textbooks and, with only a few notable exceptions, relegated to the far corners of biology conferences, this paper is written with two goals in mind. The first goal is to summarize the extensive experimental record produced by biologists, botanists, and zoologists, identifying the strong correlation between metabolic processes and orbital periodicities. The second goal is to suggest experiments that might provide insight into how metabolic processes and gravitation might be so coupled.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"115-135"},"PeriodicalIF":0.0,"publicationDate":"2021-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1914913","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39277107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Regulation of diverse nuclear shapes: pathways working independently, together. 对不同核形状的调控：独立工作和共同工作的途径。

Communicative and Integrative Biology Pub Date : 2021-07-05 eCollection Date: 2021-01-01 DOI: 10.1080/19420889.2021.1939942

Pallavi Deolal, Krishnaveni Mishra

{"title":"Regulation of diverse nuclear shapes: pathways working independently, together.","authors":"Pallavi Deolal, Krishnaveni Mishra","doi":"10.1080/19420889.2021.1939942","DOIUrl":"10.1080/19420889.2021.1939942","url":null,"abstract":"Membrane-bound organelles provide physical and functional compartmentalization of biological processes in eukaryotic cells. The characteristic shape and internal organization of these organelles is determined by a combination of multiple internal and external factors. The maintenance of the shape of nucleus, which houses the genetic material within a double membrane bilayer, is crucial for a seamless spatio-temporal control over nuclear and cellular functions. Dynamic morphological changes in the shape of nucleus facilitate various biological processes. Chromatin packaging, nuclear and cytosolic protein organization, and nuclear membrane lipid homeostasis are critical determinants of overall nuclear morphology. As such, a multitude of molecular players and pathways act together to regulate the nuclear shape. Here, we review the known mechanisms governing nuclear shape in various unicellular and multicellular organisms, including the non-spherical nuclei and non-lamin-related structural determinants. The review also touches upon cellular consequences of aberrant nuclear morphologies.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"158-175"},"PeriodicalIF":0.0,"publicationDate":"2021-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39184598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cooling effect of fungal stromata in the Dactylis-Epichloë-Botanophila symbiosis. Dactylis-Epichloë-Botanophila共生真菌基质的降温作用。

Communicative and Integrative Biology Pub Date : 2021-06-27 eCollection Date: 2021-01-01 DOI: 10.1080/19420889.2021.1938824

Marlena Lembicz, Zbigniew Miszalski, Andrzej Kornaś, Katarzyna Turnau

{"title":"Cooling effect of fungal stromata in the Dactylis-Epichloë-Botanophila symbiosis.","authors":"Marlena Lembicz, Zbigniew Miszalski, Andrzej Kornaś, Katarzyna Turnau","doi":"10.1080/19420889.2021.1938824","DOIUrl":"https://doi.org/10.1080/19420889.2021.1938824","url":null,"abstract":"The stromata of Epichloë fungi are structures covering part of the stem of grasses. Under the fungal layer, still green tissues of the plant survive, although the development of the new leaves is inhibited. Stromata are the places where conidia and ascospores develop. Also, here Botanophila flies dine on mycelium, lay the eggs, defecate, and the larvae develop. The interaction of the three symbionts was analyzed concerning the organisms' adaptation to understand the differences in physiology and ecology of this microenvironment that support stable symbiosis spreading presently in Europe since the beginning of the XXI century. For analysis of the infrared radiation emitted by stromata, a high-resolution infrared camera FLIR E50 was used. The visualization of stromata temperature profiles was shown in the form of pseudo-colored (false) infrared images. The 13C discrimination was used to characterize photosynthesis of the plant tissue enclosed within the stromata. The stromata had a substantially lower temperature than the green plant tissues. The difference reached ~5.6°C during midday hours, whereas it was smaller in the evening, reaching only ~3.6°C. The mycelium of Epichloë cultivated on agar showed about 2°C lower temperature in comparison to the surrounding. The plant tissues enclosed within the stroma were photosynthetically active, although this activity was of phosphoenolpyruvate carboxylase (PEPC) type and less involved in heat dissipation during the day. The stromata, built by fungal hyphae, on which fungal reproductive structures develop, form a cool shelter. This shelter provides a place for the larvae of Botanophila flies.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"151-157"},"PeriodicalIF":0.0,"publicationDate":"2021-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1938824","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39166672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Microbial amelioration of salinity stress in HD 2967 wheat cultivar by up-regulating antioxidant defense. 微生物通过上调抗氧化防御能力改善 HD 2967 小麦品种的盐度胁迫。

Communicative and Integrative Biology Pub Date : 2021-06-24 eCollection Date: 2021-01-01 DOI: 10.1080/19420889.2021.1937839

Madhulika Singh, Neha Tiwari

{"title":"Microbial amelioration of salinity stress in HD 2967 wheat cultivar by up-regulating antioxidant defense.","authors":"Madhulika Singh, Neha Tiwari","doi":"10.1080/19420889.2021.1937839","DOIUrl":"10.1080/19420889.2021.1937839","url":null,"abstract":"An experiment was conducted to investigate the potential of Piriformospora indica and plant growth-promoting bacteria (PGPB) to ameliorate salinity stress in HD 2967 wheat cultivar. Plants were treated with four different levels of salinity viz. 0, 50, 100 and 200 mM NaCl (electrical conductivity value 0.01, 5.84, 11.50 and 21.4 mS cm-1, respectively) under greenhouse conditions, using a completely randomized design experiment. Plants inoculated with PGPB and P. indica showed decrease in lipid peroxidation, relative membrane permeability and lipoxygenase enzyme (LOX) activity as compared to uninoculated plants. The result of this study showed that PGPB and P. indica inoculated HD 2967 wheat plants accumulated higher content of proline, α-tocopherol and carotenoid as compared to uninoculated plants. The HD 2967 wheat plants either inoculated with PGPB or P. indica showed significantly higher activities of antioxidant enzymes viz. superoxide dismutase, catalase and ascorbate peroxidase than that of the uninoculated plants. Moreover, PGPB inoculated plants showed greater activity of antioxidant enzymes than the plants inoculated with P. indica. Salinity stress tolerance was more pronounced in the PGPB inoculated than P. indica inoculated plants. This study revealed the potentiality of PGPB and P. indica as bio-ameliorator under salinity stress, and suggests that this plant microbial association could be a promising biotechnological tool to combat the deleterious effects of salinity stress.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"136-150"},"PeriodicalIF":0.0,"publicationDate":"2021-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39166671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A unifying theory of physics and biological information through consciousness. 通过意识统一物理和生物信息的理论。

Communicative and Integrative Biology Pub Date : 2021-06-08 DOI: 10.1080/19420889.2021.1907910

Pollard-Wright Holly

{"title":"A unifying theory of physics and biological information through consciousness.","authors":"Pollard-Wright Holly","doi":"10.1080/19420889.2021.1907910","DOIUrl":"https://doi.org/10.1080/19420889.2021.1907910","url":null,"abstract":"This article represents a transdisciplinary theory that attempts, in a nonmathematical way, to reconcile some contemporary concepts of physics with a novel theory of the mind. It represents a thought experiment that consolidates complexity by melding certain unifying natural science concepts into a coherent reality. The foundations of quantum mechanics and the cosmological mysteries of dark energy, dark matter, and normal matter non-dogmatically explained may be accessible to individuals other than those immersed in mathematical formulas. Through reasoning and models, terms are defined and illustrations provided, further clarifying concepts. In this theory, consciousness represents dynamic differences that come to an end. It exists through interdependent relationships between dark energy, focal points of dark matter (FPDMs), and normal matter with associated states of mind: pure awareness, pure mental state, and mental images state, respectively. Consciousness enables the emergence of an observing ego, a viewpoint that defines conscious events but which is not consciousness in and of itself. For topics described throughout the article, there is a mental and physical aspect that through relationship produces change that makes a difference. In this way, the reader, an 'observing ego,' with a human cognitive viewpoint, may bridge the 'gap' connecting the mental and physical domains. Although the theory can be developed mathematically in more detail, the main emphasis is to provide an intriguing explanation of how physics melds with 'mind,' thus laying the foundation for future explorations into how this theoretical framework of the mind reciprocates with other areas of science.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"78-110"},"PeriodicalIF":0.0,"publicationDate":"2021-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/19420889.2021.1907910","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39113812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A cell wall-localized glycine-rich protein of dodder acts as pathogen-associated molecular pattern. 菟丝子细胞壁定位的富含甘氨酸的蛋白作为病原体相关的分子模式。

Communicative and Integrative Biology Pub Date : 2021-05-03 DOI: 10.1080/19420889.2021.1918369

Peter Slaby, Max Körner, Markus Albert

引用次数: 2

Therapeutic application of light and electromagnetic fields to reduce hyper-inflammation triggered by COVID-19. 光和电磁场的治疗应用可减轻 COVID-19 引发的炎症反应。

Communicative and Integrative Biology Pub Date : 2021-04-29 DOI: 10.1080/19420889.2021.1911413

Marootpong Pooam, Blanche Aguida, Soria Drahy, Nathalie Jourdan, Margaret Ahmad

{"title":"Therapeutic application of light and electromagnetic fields to reduce hyper-inflammation triggered by COVID-19.","authors":"Marootpong Pooam, Blanche Aguida, Soria Drahy, Nathalie Jourdan, Margaret Ahmad","doi":"10.1080/19420889.2021.1911413","DOIUrl":"10.1080/19420889.2021.1911413","url":null,"abstract":"COVID-19 - related morbidity is associated with exaggerated inflammation and cytokine production in the lungs, leading to acute respiratory failure. The cellular mechanisms underlying these so-called 'cytokine storms' are regulated through the Toll-like receptor 4 (TLR4) signaling pathway and by ROS (Reactive Oxygen Species). Both light (Photobiomodulation) and magnetic fields (e.g., Pulsed Electro Magnetic Field) stimulation are noninvasive therapies known to confer anti-inflammatory effects and regulate ROS signaling pathways. Here we show that daily exposure to two 10-minute intervals of moderate intensity infra-red light significantly lowered the inflammatory response induced via the TLR4 receptor signaling pathway in human cell cultures. Anti-inflammatory effects were likewise achieved by electromagnetic field exposure of cells to daily 10-minute intervals of either Pulsed Electromagnetic Fields (PEMF), or to Low-Level static magnetic fields. Because current illumination and electromagnetic field therapies have no known side effects, and are already approved for some medical uses, we have here developed protocols for verification in clinical trials of COVID-19 infection. These treatments are affordable, simple to implement, and may help to resolve the acute respiratory distress of COVID-19 patients both in the home and in the hospital.","PeriodicalId":39647,"journal":{"name":"Communicative and Integrative Biology","volume":"14 1","pages":"66-77"},"PeriodicalIF":0.0,"publicationDate":"2021-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38905760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human vault RNA1-1, but not vault RNA2-1, modulates synaptogenesis. 人类穹窿RNA1-1调节突触发生，而不是穹窿RNA2-1。

Communicative and Integrative Biology Pub Date : 2021-04-14 DOI: 10.1080/19420889.2021.1909229

Shuji Wakatsuki, Moeka Ohno, Toshiyuki Araki

引用次数: 3