{"title":"Effects of combining rehabilitation training on the recovery of athletic ability after reconstruction of injured ligament.","authors":"Haocheng Sun","doi":"10.1080/03091902.2024.2386992","DOIUrl":"10.1080/03091902.2024.2386992","url":null,"abstract":"<p><p>This paper aims to investigate the impact of conventional rehabilitation training and neuromuscular electrical stimulation (NMES) on the recovery of motor abilities in patients following ligament injury reconstruction. Forty postoperative patients who underwent surgery for anterior cruciate ligament reconstruction (ACLR) were randomly allocated to either the conventional rehabilitation group or the NMES group. The NMES group received NMES treatment in addition to the conventional rehabilitation program starting from eight weeks postoperatively. Various parameters, including knee joint function, stability, and balance, were compared between the two groups at eight weeks and 12 weeks postoperatively. Compared to the data at eight weeks postoperatively, both groups exhibited significant improvements in all measured indicators at 12 weeks postoperatively (<i>p</i> < 0.05). In the 12<sup>th</sup> week after the surgery, the NMES group demonstrated a Lysholm score of 93.18 ± 3.67 points, an IKDC score of 84.65 ± 2.33 points, a KT-2000 measurement of 0.88 ± 0.45 mm, a thigh circumference difference of -1.33 ± 0.55 cm, a knee flexion angle of 130.12 ± 4.21°, a single-leg standing time of 60.12 ± 9.33 s, a YBT score of 70.26 ± 2.68 points, and a Bulgarian split squat 1RM size of 58.07 ± 6.85 kg; all of these results were significantly superior to those observed in the conventional group (<i>p</i> < 0.05). NMES significantly enhances the recovery of athletic ability in patients following postoperative ACLR and can be effectively applied in clinical practice.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":"48 3","pages":"92-99"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Kao, Jason O Germany, Abhijith Shasheendra, Ketan Mhetre, Xu Wang, Kristyn Ringgold, Sahil Patel, Ashley Emery, Eileen M Bulger, Nathan White, Shahram Aarabi
{"title":"Therapeutic limb hypothermia for the treatment of traumatic acute limb ischemia.","authors":"Emily Kao, Jason O Germany, Abhijith Shasheendra, Ketan Mhetre, Xu Wang, Kristyn Ringgold, Sahil Patel, Ashley Emery, Eileen M Bulger, Nathan White, Shahram Aarabi","doi":"10.1080/03091902.2024.2362667","DOIUrl":"10.1080/03091902.2024.2362667","url":null,"abstract":"<p><p>Acute limb ischaemia (ALI) is an emergent clinical condition that strains pre-hospital resources and impacts healthcare costs and patient quality of life. Hypothermia has long been used in clinical and research settings to mitigate ischaemic damage in tissues, but prompt reperfusion is needed to prevent loss of limb or function from ALI. To address the unmet need for pre-hospital intervention of threatened limbs awaiting definitive specialty care, we have focused on controlled application of hypothermia. Over years of animal experiments, phantom limb creation, and materials selection, we conceptualised and created a portable limb-cooling device that can be used alone or combined with a traditional tourniquet or resuscitative endovascular balloon occlusion of the aorta. Here, we describe our process of building and testing the device, from computer simulation through animal-limb metabolic studies, to prototype testing.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"39-47"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majid Sepahvand, Maytham N Meqdad, Fardin Abdali-Mohammadi
{"title":"Fault tolerance challenges in wearable computing for vital applications: a survey.","authors":"Majid Sepahvand, Maytham N Meqdad, Fardin Abdali-Mohammadi","doi":"10.1080/03091902.2024.2371789","DOIUrl":"10.1080/03091902.2024.2371789","url":null,"abstract":"<p><p>Wearable computers can be used in different domains including healthcare. However, due to suffering from challenges such as faults their applications may be limited in real practice. So, in designing wearable devices, designer must take into account fault tolerance techniques. This study aims to investigate the challenging issues of fault tolerance in wearable computing. For this purpose, different aspects of fault tolerance in wearable computing namely hardware, software, energy, and communication are studied; and state of the art research regarding each category is analysed. In this analysis, the performed works using the fault tolerance techniques are included in the form of 25 components and referred to as \"fault tolerance plan\". Using this fault tolerance plan and the appropriate profile, the fault tolerance of any wearable system can be evaluated. In this article, fault tolerances of several of the most prominent works conducted in the field of wearable computing were evaluated. The obtained results, with the medical profile, showed that only one wearable system had a fault tolerance of 91%, with the other systems having a fault tolerance of 24% or less. Also, the results obtained from evaluating these works, with the military profile, showed that only one wearable system had a fault tolerance of 76%, with the other systems having a fault tolerance of 19% or less. These mean that few studies have been conducted on the fault tolerance of wearable computing.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"48-63"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"News and product update.","authors":"","doi":"10.1080/03091902.2024.2330796","DOIUrl":"https://doi.org/10.1080/03091902.2024.2330796","url":null,"abstract":"","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":"48 2","pages":"77-79"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nasima Akter Mukta, Samina Ahmed, A M Sarwaruddin Chowdhury, M Nuruzzaman Khan, Md Sahadat Hossain, Gawsia W Chowdhury, Papia Haque
{"title":"PLA blended gelatine-based nanofibrous mats with enhanced hydrophobicity for soft tissue regeneration.","authors":"Nasima Akter Mukta, Samina Ahmed, A M Sarwaruddin Chowdhury, M Nuruzzaman Khan, Md Sahadat Hossain, Gawsia W Chowdhury, Papia Haque","doi":"10.1080/03091902.2024.2379840","DOIUrl":"10.1080/03091902.2024.2379840","url":null,"abstract":"<p><p>Wound healing requires a substantial amount of moisture for faster recovery. Completely hydrophobic or hydrophilic biomaterials are not suitable to be applied for cell growth in wounded areas. The study aimed to prepare a nanofibrous scaffold from the blend of a solution of hydrophobic PLA and a solution of hydrophilic gelatine. The stability of the blend was achieved using a surfactant and an electrospun nanofibrous scaffold was made out of the solution. The optimum composition of gelatine and PLA to make a scaffold of uniform fibre diameter was achieved with the help of conductivity, viscosity and FESEM analysis. The optimum scaffold was characterised by TGA, DSC and XRD analysis. The water contact angle of the optimum sample was observed at 27°. The blended scaffold was found non-toxic to cells and showed a 30% faster healing of wounds in the rat model test compared to the healing rate of the PLA scaffold or the gelatine scaffold alone. The histological assay also supported the blend scaffold as an encouraging material for tissue regeneration.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"64-76"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141634898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"News and product update.","authors":"J Fenner","doi":"10.1080/03091902.2024.2301846","DOIUrl":"https://doi.org/10.1080/03091902.2024.2301846","url":null,"abstract":"","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139522008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maximally stable extremal regions-based algorithm for automatic interpretation of disc-diffusion antibiotic sensitivity test.","authors":"Padma Ganasala","doi":"10.1080/03091902.2024.2356622","DOIUrl":"10.1080/03091902.2024.2356622","url":null,"abstract":"<p><p>Antibiotic resistance causes a major threat to patients suffering from infectious diseases. Accurate and timely assessment of Antibiotic Susceptibility Test (AST) is of great importance to ensure adequate treatment for patients and for epidemiological monitoring. Disc Diffusion Test (DDT) is a standard and widely used method for AST. Manual interpretation of DDT results is a tedious task and susceptible to human errors. Computer vision-based automated interpretation of DDT results will speed up the process and reduces the manpower requirement. This would assist the physician to initiate the antibiotic treatment for the patients on time and results in saving the patient's life. The crucial step in automatic interpretation of DDT result is to measure and present the diameter of zone of inhibition without manual intervention. The existing methods require manual interventions at various stages during inhibition zone diameter measurement for some typical cases. This issue is addressed in the present work through maximally stable extremal regions (MSER) based algorithm. Dataset consisting of 60 agar plate images that includes different agar medium, images having different resolution and visual quality is used to validate the proposed method. Experimental results demonstrated that there is a strong correlation between standard method and the proposed method.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"25-34"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subrata Mondal, David B MacManus, Rajesh Ghosh, Abhishek Banagunde, Nicholas Dunne
{"title":"A numerical investigation of stress, strain, and bone density changes due to bone remodelling in the talus bone following total ankle arthroplasty.","authors":"Subrata Mondal, David B MacManus, Rajesh Ghosh, Abhishek Banagunde, Nicholas Dunne","doi":"10.1080/03091902.2024.2355319","DOIUrl":"10.1080/03091902.2024.2355319","url":null,"abstract":"<p><p>Total ankle arthroplasty is the gold standard surgical treatment for severe ankle arthritis and fracture. However, revision surgeries due to the <i>in vivo</i> failure of the ankle implant are a serious concern. Extreme bone density loss due to bone remodelling is one of the main reasons for <i>in situ</i> implant loosening, with aseptic loosening of the talar component being one of the primary reasons for total ankle arthroplasty revisions. This study is aimed at determining the performance and potential causes of failure of the talar component. Herein, we investigated the stress, strain, and bone density changes that take place in the talus bone during the first 6 months of bone remodelling due to the total ankle arthroplasty procedure. Computed tomography scans were used to generate the 3D geometry used in the finite element (FE) model of the Intact and implanted ankle. The Scandinavian Total Ankle Replacement (STAR™) CAD files were generated, and virtual placement within bone models was done following surgical guidelines. The dorsiflexion physiological loading condition was investigated. The cortical region of the talus bone was found to demonstrate the highest values of stress (5.02 MPa). Next, the adaptive bone remodelling theory was used to predict bone density changes over the initial 6-month post-surgery. A significant change in bone density was observed in the talus bone due to bone remodelling. The observed quantitative changes in talus bone density over 6-month period underscore potential implications for implant stability and fracture susceptibility. These findings emphasise the importance of considering such biomechanical factors in ankle implant design and clinical management.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141307046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malvika Nagrath, Alireza Rahimnejad Yazdi, Daniella Marx, Tiffany Ni, Reid C Gallant, Heyu Ni, Mark R Towler
{"title":"<i>In vitro</i> analysis of tantalum-containing mesoporous bioactive glass fibres for haemostasis.","authors":"Malvika Nagrath, Alireza Rahimnejad Yazdi, Daniella Marx, Tiffany Ni, Reid C Gallant, Heyu Ni, Mark R Towler","doi":"10.1080/03091902.2024.2356618","DOIUrl":"10.1080/03091902.2024.2356618","url":null,"abstract":"<p><p>Haemorrhage is the leading cause of battlefield deaths and second most common cause for civilian mortality worldwide. Biomaterials-based haemostatic agents are used to aid in bleeding stoppage; mesoporous bioactive glasses (MBGs) are candidates for haemostasis. Previously made Tantalum-containing MBG (Ta-MBG) powders' compositions were fabricated as electrospun <i>fibres</i> for haemostatic applications in the present study. The fibres were fabricated to address the challenges associated with the powder form: difficult to compress without gauze, getting washed away in profuse bleeding, generating dust in the surgical environment, and forming thick callus-difficult to remove for surgeons and painful for patients. Ta-MBGs were based on (80-<i>x</i>)SiO<sub>2</sub>-15CaO-5P<sub>2</sub>O<sub>5</sub>-<i>x</i>Ta<sub>2</sub>O<sub>5</sub> mol% compositions with <i>x</i> = 0 (0Ta), 0.5 (0.5Ta), 1 (1Ta), and 5 (5Ta) mol%. The present study details the fibres' <i>in vitro</i> analyses, elucidating their cytotoxic effects, and haemostatic capabilities and relating these observations to fibre chemistry and previously fabricated powders of the same glasses. As expected, when Ta addition is increased at the expense of silica, a new FTIR peak (non-bridging oxygen-silicon, Si-NBO) develops and Si-O-Si peaks become wider. Compared to 0Ta and 1Ta fibres, 0.5Ta show Si-O peaks with reduced intensity. The fibres had a weaker intensity of Si-NBO peaks and release fewer ions than powders. A reduced ion profile provides fibres with a stable matrix for clot formation. The ion release profile for 1Ta and 5Ta fibres was significantly lower than 0Ta and 0.5Ta fibres. Ta-MBGs were not found to be cytotoxic to primary rat fibroblasts using a methyl thiazolyl tetrazolium (MTT) assay. Furthermore, a modified activated partial thromboplastin time assay analysing the fibrin absorbance showed that the absorption increases from physiological clotting < 0Ta < 0.5Ta < 5Ta < commercial haemostat, Surgical SNoW<sup>TM</sup>, Ethicon, USA < 1Ta. Higher absorption signifies a stronger clot. It is concluded that Ta-MBG fibres can provide stable matrix for clot formation and 1Ta can potentially enhance clotting best among other Ta-MBGs.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"12-24"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the performances of various controllers adopted in the biomedical field for blood glucose regulation: a case study of the type-1 diabetes.","authors":"Isah Ndakara Abubakar, Moad Essabbar, Hajar Saikouk","doi":"10.1080/03091902.2024.2353036","DOIUrl":"10.1080/03091902.2024.2353036","url":null,"abstract":"<p><p>Diabetes remains a critical global health concern that necessitates urgent attention. The contemporary clinical approach to closed-loop care, specifically tailored for insulin-dependent patients, aims to precisely monitor blood glucose levels while mitigating the risks of hyperglycaemia and hypoglycaemia due to erroneous insulin dosing. This study seeks to address this life-threatening issue by assessing and comparing the performance of different controllers to achieve quicker settling and convergence rates with reduced steady-state errors, particularly in scenarios involving meal interruptions. The methodology involves the detection of plasma blood glucose levels, delivery of precise insulin doses to the actuator through a control architecture, and subsequent administration of the calculated insulin dosage to patients based on the control signal. Glucose-insulin dynamics were modelled using kinetics and mass balance equations from the Bergman minimal model. The simulation results revealed that the PID controller exhibited superior performance, maintaining blood glucose concentration around the preferred threshold ∼98.8% of the time, with a standard deviation of 2.50. This was followed by RST with a success rate of 98.5% and standard deviation of 5.00, SPC with a success rate of 58% and standard deviation of 2.99, SFC with a success rate of 55% and standard deviation of 10.08, and finally LCFB with a rate of 10% and significantly higher standard deviation of 64.55.</p>","PeriodicalId":39637,"journal":{"name":"Journal of Medical Engineering and Technology","volume":" ","pages":"376-388"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}