Nano Today最新文献

{"title":"Biohybrid decellularized peritumoral tissue hydrogel for liver failure treatment","authors":"Dongxue Ge ,&nbsp;Zhongxia Wang ,&nbsp;Dayu Chen ,&nbsp;Feng Li ,&nbsp;Haozhen Ren","doi":"10.1016/j.nantod.2025.102968","DOIUrl":"10.1016/j.nantod.2025.102968","url":null,"abstract":"<div><div>Tissue engineering is considered a promising therapeutic strategy for acute liver failure (ALF), yet it is currently limited by the lack of natural scaffold materials and effective regeneration promoting approaches. Here, we propose a therapeutic strategy using a biohybrid decellularized peritumoral tissue hydrogel loaded with stem cell exosomes (exos) are applied to treat liver failure. Specifically, tissue samples obtained during clinical procedures are typically discarded as medical waste but can serve as natural scaffolds for therapeutic applications. Benefiting from a mild decellularization process, the decellularized peritumoral tissue retains amounts of bioactive substances while maintaining low immunogenicity. Moreover, induced pluripotent stem cell-derived hepatocytes (iPS-Heps) cultured within the decellularized extracellular matrix (dECM) hydrogel exhibit robust metabolic activity. More importantly, the incorporation of mesenchymal stem cells (MSCs) exos enables the effective integration of their inherent regenerative cytokines into the hydrogel. In vitro studies demonstrate that the hydrogel expresses high levels of liver functions, such as albumin (ALB) and the Cytochrome P450 proteins (CYP) family. In a <span>D</span>-galactosamine-induced liver failure rat model, the exos-loaded dECM hydrogel considerably improves survival rates, alleviates liver necrosis, and suppresses local inflammatory responses. This approach not only preserves bioactive substances from the tissue but also enhances metabolic activity in hepatocytes, thereby offering potential for improved clinical outcomes.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102968"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the druggable proteome strategies and innovations in targeted protein degradation","authors":"Ke Ma ,&nbsp;Ting Liu ,&nbsp;Wen-Bo Huan,&nbsp;Ke-Zheng Chen,&nbsp;Sheng-Lin Qiao","doi":"10.1016/j.nantod.2025.102945","DOIUrl":"10.1016/j.nantod.2025.102945","url":null,"abstract":"<div><div>Targeted Protein Degradation (TPD) emerges as a novel therapeutic strategy that selectively eliminates disease-causing proteins by harnessing endogenous degradation systems, thereby overcoming the limitations of traditional drugs in addressing “undruggable” targets. This review outlines the core molecular mechanisms and primary technical platforms of TPD, including PROTACs, molecular glues (MGs), antibody-degradation conjugates, and emerging autophagy-related strategies (LYTACs, AUTACs, ATTECs, etc.). It systematically summarizes molecular engineering advances such as linker optimization, expansion of E3 ligase resources, and environmentally responsive and multi-modular designs. Furthermore, clinical and translational research cases demonstrate TPD's application potential across oncology, neurodegenerative diseases, cardiovascular disorders, and infectious diseases. Addressing challenges such as suboptimal pharmacokinetics, delivery limitations, potential off-target effects, and industrialization hurdles, we identify critical scientific questions requiring resolution and highlight emerging directions including AI-enabled design, nanomaterial delivery, and interdisciplinary integration. Overall, TPD is propelling drug development from “functional inhibition” toward “protein clearance,” injecting new vitality into precision medicine. This paper aims to provide a systematic reference for subsequent research and clinical translation.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102945"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145682140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic composite engineering: Bridging immunomodulaftion, bone regeneration and precision therapy in osteosarcoma management","authors":"Chaoqun You ,&nbsp;Shuai Zhang ,&nbsp;Jie Jiang ,&nbsp;Jiuhui Xu ,&nbsp;Fanwei Zeng ,&nbsp;Tingting Ren ,&nbsp;Yujing Li ,&nbsp;Xiaodong Tang ,&nbsp;Ran Wei","doi":"10.1016/j.nantod.2025.102952","DOIUrl":"10.1016/j.nantod.2025.102952","url":null,"abstract":"<div><div>Osteosarcoma is the most common primary malignant bone tumor. It presents two major clinical challenges: aggressive tumor progression and extensive bone destruction. Traditional treatments often fail to achieve both complete tumor eradication and effective skeletal reconstruction. Recent advances in multifunctional composite biomaterials have made it possible to integrate tumor ablation, immune modulation, and bone regeneration into unified therapeutic systems. This review classifies these platforms according to material dimensionality (nanoscale, microscale, and macroscale) and examines targeted delivery strategies, including responsive release, external stimuli, and monofunctional optimization. We also highlight emerging synergistic systems that combine photothermal therapy, chemotherapy, metabolic interference, gene regulation, and mechanical support to produce coordinated therapeutic effects. Particular attention is given to metabolic–bone coupling and gene–mechanical synergy, which represent new strategies for simultaneously inhibiting tumor progression and promoting osteogenesis. Building on our original framework, we now map the osteosarcoma immune microenvironment and highlight precision immunoregulation enabled by materials, targeting T lymphocytes, natural killer cells, the axis of tumor associated macrophages and osteoclasts, and dendritic cells and B lymphocytes, to better couple tumor control with bone regeneration. Finally, we outline key translational challenges—such as mismatched degradation and therapeutic windows, tumor-promoting effects of osteogenic signaling, and biological heterogeneity—and propose future directions for developing precision-engineered, adaptive platforms for osteosarcoma management.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102952"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145734044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aerogels as next-generation electrocatalysts for water electrolysis and beyond","authors":"Balamurugan Muthukutty ,&nbsp;Ponnaiah Sathish Kumar ,&nbsp;Jun-Hyung Im ,&nbsp;Periakaruppan Prakash ,&nbsp;Daeho Lee ,&nbsp;Young-Ki Kim","doi":"10.1016/j.nantod.2025.102901","DOIUrl":"10.1016/j.nantod.2025.102901","url":null,"abstract":"<div><div>The rising energy demand and depletion of conventional fuels have led to intensified interest in water-splitting as a sustainable clean energy resolution. Accordingly, developing efficient catalytic materials have become vital for advancing key electrochemical processes, including the oxygen evolution reaction (OER), hydrogen evolution reaction (HER), and overall water electrolysis, which are essential for energy conversion technologies (e.g., metal-air batteries, fuel cells, and water-splitting devices). Given the need for innovative solutions in this domain, aerogel (AG)-based materials have emerged as leading candidates, distinguished by their highly porous microstructure, tunable properties, and diverse synthesis approaches. The goal of this review is to offer a thorough examination of AG catalysts, elucidating why they are pivotal for addressing current challenges in electrocatalysis. We explore their synthesis techniques, structural characterization methods, and roles in enhancing electrochemical kinetics and electrode activity. The discussion extends to their ability to lower overpotentials, boost catalytic performance, and prolong cycle life, making them indispensable for sustainable energy applications. Furthermore, the incorporation of Density Functional Theory (DFT) as a computational tool provides deeper insights into molecular pathways and reaction mechanisms in water-splitting, strengthening the connection between experimental and theoretical studies. Finally, this review identifies future directions and addresses the challenges in developing cost-effective, high-efficiency AG-based catalysts, underscoring their potential to transform clean energy production.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102901"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailored apoptotic vesicles promote bone regeneration by stepping on osteoinductive accelerator via ITGA10-AKT signaling activation","authors":"Yuhe Jiang ,&nbsp;Zeying Wang ,&nbsp;Ruiyi Guo ,&nbsp;Yike Liao ,&nbsp;Hao Qiu ,&nbsp;Yunsong Liu ,&nbsp;Ping Zhang ,&nbsp;Yuan Zhu ,&nbsp;Wenyue Li ,&nbsp;Xiao Zhang ,&nbsp;Yongsheng Zhou","doi":"10.1016/j.nantod.2025.102912","DOIUrl":"10.1016/j.nantod.2025.102912","url":null,"abstract":"<div><div>Apoptotic vesicles (apoVs) have shown good potential in treating bone disease including osteoporosis. However, the efficient production of highly energetic apoVs is one of the critical limitations for their clinical applications. In this study, we contributed to reconstructing a gradual senescence process in mesenchymal stem cell (MSC)-derived apoVs. Our findings displayed that their essential properties remained consistent throughout replicative aging and individual’s aging. Nevertheless, their protein composition and biological functions were significantly altered by the age of donor. Through proteomic assay, we identified integrin α 10 (ITGA10) as a highly efficient apoV osteoinductivity accelerator in both humans and mice, and have targeted it for apoV customization. On this basis, we demonstrated accelerator-based approaches to prepare amounts of ITGA10-enriched apoVs by magnetic-activated sorting and sonic loading. These engineered apoVs proved effective in ameliorating osteoprotic bone loss. Their osteoinductivity was attributed to the activation of downstream AKT signaling in recipient MSCs by the high content of ITGA10. In summary, we have laid the groundwork for customizing apoVs through an accelerator-based strategy, aiming to obtain superior therapeutic effectors in the field of bone regenerative biomedicine.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102912"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145263042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In situ TEM study of radiation tolerance of Fe-substituted hollandite","authors":"Yuhan Li ,&nbsp;Tao Ma ,&nbsp;Nanjun Chen ,&nbsp;Mingyang Zhao ,&nbsp;Kyle S. Brinkman ,&nbsp;Jake Amoroso ,&nbsp;Shenyang Hu ,&nbsp;Kai Sun ,&nbsp;Li Jiang ,&nbsp;Fei Gao ,&nbsp;Lumin Wang","doi":"10.1016/j.nantod.2025.102929","DOIUrl":"10.1016/j.nantod.2025.102929","url":null,"abstract":"<div><div>Nuclear waste forms are materials designed to encase and isolate radioactive isotopes. This material form ensures safe containment and minimizes the release of harmful radiation into the environment. The radiation stability of the material during radioactive decay of the encapsulated isotopes is an important property to evaluate for waste forms as a long-term storage solution for nuclear waste. In this study, the radiation tolerance of a series of Ba_1.33₋_<em>x</em>Cs_<em>x</em>Fe_2.66₋_<em>x</em>Ti_{5.34+<em>x</em>}O₁₆ hollandite (<em>x</em> = 0, 0.67, and 1.33), designed as a nuclear waste form, especially for Cs, are investigated under electron and ion beam irradiation with <em>in situ</em> transmission electron microscopy (TEM) characterization at nano and atomic scale. The results show a high resistance to amorphization and inconspicuous Cs loss under ionizing radiation with electron fluences up to 1.26 × 10²⁴ cm⁻², equivalent to an ionizing energy deposition of 3.43 × 10¹⁴ Gy, surpassing the total ionizing dosage of ∼10¹¹ Gy resulting from the beta- and gamma-decay of ¹³⁷Cs over 10 half-lives. However, both Ba- and Cs- end members of the hollandite are completely amorphized below a displacement dose of 0.3 displacement per atom (dpa) under 1.2 MeV heavy ions (Kr³⁺) at 200 ℃ as the result of nano scale displacement cascade quenching, indicating that the structure will not be stable if used to encapsulate transuranic elements (TRU). The results also indicate that the Cs-end member of the hollandite required 60 % higher dose than the Ba-end member to become amorphous. Density Functional Theory (DFT) simulations were performed to elucidate and comprehend the experimental results of the ion irradiation experiments. The high tolerance to electron radiation of the hollandite phases with high loading of beta-decay isotopes also makes it a potential candidate material for the key component in beta voltaic nuclear batteries.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102929"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Nanosynergist-engineered oncolytic adenovirus enhancing immune-virotherapy efficacy for glioblastoma via interrupting antiviral responses” [Nano Today 57 (2024) 102328]","authors":"Jinliang Xu ,&nbsp;Xiaoxiao Liu ,&nbsp;Junqiang Ding ,&nbsp;Hanchang Zhang ,&nbsp;Tingting Yao ,&nbsp;Sha Li ,&nbsp;Rong Yang ,&nbsp;Nianhui Yu ,&nbsp;Qi Yue ,&nbsp;Changyou Zhan ,&nbsp;Xihui Gao","doi":"10.1016/j.nantod.2025.102970","DOIUrl":"10.1016/j.nantod.2025.102970","url":null,"abstract":"","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102970"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rational design of extracellular vesicles for targeted drug delivery across physiological barriers","authors":"Helna M. Baby ,&nbsp;Hengli Zhang ,&nbsp;Andrew Selvadoss ,&nbsp;Tanvi V. Pathrikar ,&nbsp;Ambika G. Bajpayee","doi":"10.1016/j.nantod.2025.102920","DOIUrl":"10.1016/j.nantod.2025.102920","url":null,"abstract":"<div><div>Extracellular vesicles (EVs) are naturally secreted, non-nuclear lipid nanostructures by biological sources with intrinsic features such as biocompatibility, low immunogenicity, and the ability to bypass biological barriers. Despite the growing interest in EV research, their biological potential as a versatile drug delivery vehicle has yet to be widely translated for clinical use. Fewer than 3 % of clinical trials involving these cell-free vesicles have utilized them for drug delivery applications. This review elucidates the reasons behind the translational gap through a comprehensive analysis of pharmacokinetic and tissue transport challenges faced by EVs across various tissue barriers, including the cartilage, blood-brain interface, ocular, gastrointestinal, and skin tissues, and summarizes their endogenous roles within these tissue microenvironments. The review also delves into key engineering design principles, presenting a portfolio of both tissue-specific and tissue-independent targeting strategies to overcome tissue barriers and enhance the precise delivery of engineered EVs. A comprehensive comparison of key factors – such as biodistribution, cellular uptake, intracellular fate, and safety profile – between EVs and benchmark synthetic platforms is also provided to guide the selection of optimal carrier designs for diverse tissue targets and further highlights the steps needed to bridge translational gaps of engineered EVs from a clinical perspective. In conclusion, the review underscores the significance of engineered EVs as a promising next-generation nanocarrier for precision nanomedicine, offering an alternative to conventional synthetic platforms.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102920"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145412557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silver chalcogenide colloidal quantum dots for NIR-to-MWIR photodetection","authors":"Vishwa Bhatt ,&nbsp;Abhishek Sharma ,&nbsp;Min-Jae Choi","doi":"10.1016/j.nantod.2025.102956","DOIUrl":"10.1016/j.nantod.2025.102956","url":null,"abstract":"<div><div>Infrared (IR) photodetectors are key components in modern optoelectronics, empowering applications across telecommunications, medical imaging, environmental monitoring, defense, and consumer electronics. Colloidal quantum dots (CQDs) have become promising semiconductors in response to growing demand for straightforward, affordable, high-performance, and environment-friendly infrared photo-sensing technologies. The growing attention in CQD-based IR photodetectors is because of their solution processability, spectral tunability, and compatibility with silicon-based platforms. Conventional-CQDs based on Pb, Hg, and Cd exhibit excellent performance, but pose usage/disposal challenges in everyday life as well as serious environmental and health risks. At this critical juncture, binary (Ag₂X; X = S, Se, Te) and ternary (AgBiX₂) silver chalcogenide CQDs have gained attention as RoHS-compliant substitutes. For near-to-mid IR detection, silver chalcogenide CQDs offer tunable bandgaps with strong absorption coefficients and favorable optoelectronic characteristics. Review highlights advance in Ag₂X and AgMX₂ CQDs IR photodetectors, examining their integration into photodetectors device-architecture based on their optoelectronic properties. Role of controlled stoichiometry, surface passivation, and interface-engineering in enhancing photodetector performance is emphasized. With global market for CQDs IR photodetectors projected to achieve milestones, this work presents thorough overview of CQD IR photodetectors, encompassing recent advancements, prevailing challenges, and prospective directions for future development.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"67 ","pages":"Article 102956"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145734045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradable multimodal biomaterials with microenvironmental adaptability and orderly delivery of H2S and bFGF for the treatment of spinal cord injury","authors":"Junqing Huang ,&nbsp;Jiamen Shen ,&nbsp;Yu Huang ,&nbsp;Yanfang Zhao ,&nbsp;Yibo Ying ,&nbsp;Yanran Bi ,&nbsp;Liuxi Chu ,&nbsp;Xinwang Ying ,&nbsp;Qian Xu ,&nbsp;Junpeng Xu ,&nbsp;Ping Wu ,&nbsp;Jiansong Ji ,&nbsp;Zhouguang Wang","doi":"10.1016/j.nantod.2025.102890","DOIUrl":"10.1016/j.nantod.2025.102890","url":null,"abstract":"<div><div>Spinal cord injury (SCI) is a complex and interactive process involving multiple pathological stages. Single-type biomaterials often struggle to rapidly adapt to the imbalanced regenerative microenvironment and orderly resolve the symptoms of different stages, resulting in slow neural regeneration and limited functional recovery. Herein, we developed a microenvironment- adaptive and time-adaptive multimodal biomaterial (custom-designed with silk fibroin hydrogel-SF and endogenous stimulus responsive nanomedicine-G@Mn, SF-G@Mn) for the treatment of SCI. Based on pathological signals after SCI, the SF-G@Mn achieves the precise release of drugs that inhibit microenvironment regulation (H₂S and Mn^2 +) and nerve regeneration drugs (basic fibroblast growth factor (bFGF)) under different needs in the early and late stages of secondary SCI through asynchronous release kinetics. In the early stages of inflammation, oxidative stress and hypoxia, Mn²⁺ can continuously decompose H₂O₂ to generate oxygen, and synergistic effects with H₂S can jointly relieve oxidative stress, improve hypoxia and inhibit inflammation, thus comprehensively adjusting the microenvironment that is not conducive to tissue repair. As the injury progresses to a later stage dominated by nerve regeneration, bFGF is slowly released to support axon growth and myelin regeneration, helping to restore the function of the damaged nerve. After this multi-dimensional, orderly and multi-stage treatment, the motor function of the SCI mice was significantly restored. In general, this work provides a pathological signal response, on-demand, orderly release of multi-modal biomaterials of drugs at different pathological stages, to achieve spatio-temporal selectivity and adaptive treatment, and provides a valuable example for the development of personalized medicine in the future.</div></div>","PeriodicalId":395,"journal":{"name":"Nano Today","volume":"66 ","pages":"Article 102890"},"PeriodicalIF":10.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}