Scholars International Journal of Obstetrics and Gynecology最新文献

{"title":"The Extracellular Vesicles: Their Role and Future in Reproduction and Embryonic Implantation","authors":"K. Osazee, Alabrah Pw","doi":"10.36348/sijog.2023.v06i06.003","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i06.003","url":null,"abstract":"Intercellular communication is an integral part of the physiological process in a living organism. Evidence has shown that a significant amount of human protein-coding genes is endowed with the production of membrane and secreted protein types. Some of these proteins possessed post-translational influence that interferes with cellular functions. Recently the concept of cell communication gravitated to the use of membrane-bound particles called Extracellular Vesicles (EVs). EVs are released from the host cell and impact on the recipient cell through its contents (Cargo). The cargo contains various particles such as lipids, proteins, RNA, and glycolipids derived from the host cells. The current widespread research in EVs has brought its mediating role in physiological and pathological processes to limelight. Though the regulatory part of EVs has been widely embraced by researchers, the discrepancy associated with its collection and isolation as well as its analysis has remained a subject of debate in the literature. The facts emanating from the literature suggest that EVs, with its prospective application in Reproductive biology, has prompted extensive research in the last decade. Its knowledge has broadened the scope of understanding the physiology and pathology scenarios involved in reproductive processes. As a potential biomarker, it has become a valuable tool for diagnosis, prognostic, and therapeutic purposes, especially in the context of reproductive processes. However, the challenges of standardizing the isolation, purification, and analyzing EVs have remained a nightmare that need to be surmounted. Emerging evidence has demonstrated its impact in gamete development, fertilization, and embryo implantation. Thus, it could serve as a platform to understand the mechanism of conception and implantation. By extension, define a therapeutic approach for women with recurrent pregnancy loss.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128623301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors and Foeto-Maternal Outcome in Preterm Labour","authors":"T. Sultana, Razia Begum, Kamrunnahar Sweety, Laila Nazneen Khan, M. A. Hossain","doi":"10.36348/sijog.2023.v06i06.002","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i06.002","url":null,"abstract":"Background: Preterm labor is one of the biggest health issues in the globe and is associated with high perinatal mortality and morbidity. A healthy pregnancy can turn into one that is at high risk for both the mother and the fetus in one of these clinical scenarios. Objective: The aim of the present study is to determine the risk factor and maternal and perinatal outcome of patients presenting with preterm labor and to evaluate the preventable causes of preterm labour. Methods: A Case control study conducted in the Department of Gynaecology and Obstetrics Dhaka Medical College Hospital, during February 2010 to July 2010. Results: A total of 50 cases having preterm labour in between 28 - 36 weeks of gestation and 50 controls having 37-40 weeks pregnancy with lobour pain were screened and enrolled in the study. Several significant risk factors were associated with preterm labour and the following risk factors were identified. Low socio-economic class, rupture of membrane (OR = -2.45), previous history of abortion (OR = 2.25), Preterm delivery (OR -9.33), and Anaemia (OR = 8.31). Conclusions: As preterm labour is grave consequences for both the mother and the newborn of preterm labor should be aim and developing awareness of pregnant mother who are high risk for preterm labor.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127881117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Complication of Repeat Cesarean Section: A Study of 100 Patients in a Tertiary Care Hospital in Bangladesh","authors":"Umme Ayesha Mst, R. Rashid, MST. Kamrun Nahaer, F. Sultana, Alina Parvin, Juthi Bhowmick","doi":"10.36348/sijog.2023.v06i06.001","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i06.001","url":null,"abstract":"Background: Worldwide, caesarean section (CS) is one of the most commonly performed obstetric procedures. Maternal mortality and morbidities associated with repeat caesarean section is an important health problem in global perspective that needs to be addressed. Objectives: To evaluate the complications of repeat caesarean section. Materials and Method: This cross-sectional descriptive study was conducted in the department of Obstetrics & Gynaecology, Rangpur medical college hospital, Rangpur from July ’18 to June ‘20 after acceptance and ethical clearance of the protocol. During data collection total admitted patient were 2123 out of which 446 caesarean section was done among them 100 patients of my study population were selected by fulfilling inclusion and exclusion criteria. After full explanation, informing the details of the purpose of the study informed written consent was obtained from the study subjects/ or her legal gardian. After Meticulous history taking thorough physical examination was done on every patient and available investigations according to the need of management was done in the hospital. Per operative and postoperative complications were noted. Information’s were collected in predesigned questionnaire and presented in tabulated form and that was finally was analyzed with the help of computer program SPSS (Statistical Package for Social Science) version 23. Result: Total patient admitted during my data collection were 2123 and of them 446 caesarean sections were done and repeat caesarean sections were 100. The incidence of repeat caesarean section was 22.42%. 35% respondents were between >25-30 years of age. Average gestational age was >36 – 40 weeks. Emergency caesarean section was done in 79% cases and elective in 21% cases. 68% patients had adhesion, 38% had uterine atonicity, 26% had injury to the surrounding structure, placenta previa was found in 7% cases and morbid adhesion of placenta was found in 3% cases. Additional procedures like blood transfusion needed in 34% cases, adhesiolysis performed in 21% cases, ICU admission needed in 16% cases, caesarean hysterectomy performed in 11% cases and B-Lynch suture in 8% cases. Among the postoperative complications wound infection occurred in 20% cases, PPH in 13% cases, UTI in 9% cases, paralytic ileus in 4% cases and postpartum psychosis in 3% cases. Maternal mortality was found in only 3% cases. Conclusion: Repeat caesarean section is associated with increased number of intraoperative and postoperative complications like adhesion, placenta previa, morbid adherent placenta, PPH, wound infection thus increasing maternal morbidity. So, the best way to reduce these morbidity and mortality by reducing primary caesarean section rates by taking judicious decision and indications should be appropriate and C/S should be done by well-trained doctors and specialists in well-equipped centre.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"24 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116265256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Elevated Serum Homocysteine Level in Women with Gestational Diabetes Mellitus","authors":"Sayeda Tania Tanzin, Md. Ashiqur Rahman, Khadija Begum, F. Choudhury, Rumysa Taher Bushra, H. Akter","doi":"10.36348/sijog.2023.v06i05.006","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.006","url":null,"abstract":"Background: In gestational diabetes mellitus (GDM), risk prediction is mostly based on maternal history and clinical risk factors and may not optimally identify high risk pregnancies. Therefore, universal screening is widely recommended. Homocysteine levels during pregnancy in women with GDM have been studied; however, it remains unclear whether hyperhomocysteinemia is a useful predictor of GDM. Objective: To determine the association of serum homocysteine level in women with gestational diabetes mellitus. Methods: Case control study was conducted in the Department of Obstetrics and Gynaecology, Institute of Child and Mother Health (ICMH), Dhaka. Pregnant women in their 24 weeks to 40 weeks of gestation attended for antenatal care diagnosed as GDM was selected as cases. Non- diabetic pregnant women matching with cases by age and gestational age were selected as control in this study. GDM was diagnosed by oral glucose tolerance test (OGTT). The serum homocysteine level of these patients was measured. Descriptive and inferential analysis was carried out using SPSS version 22.0. P-value less than 0.05 will be considered as statistically significant. Results: Among the cases fasting blood sugar (6.13 ± 0.66) and controls (4.60 ± 0.57). Similarly, 2 hours after 75 gm. glucose blood sugar among cases (8.46 ± 0.88) and controls (6.32 ± 0.96). Both results were statistically significant p=0.001. Majority of patients were at third trimester of pregnancy (67.0%). 37.5% were primigravida and 2.5% were multigravida. Mean gestational age of cases (30.25 ± 2.74) and controls (30.02 ± 3.03). Among the cases 62.1% had history of GDM where 37.9% don’t have history of GDM. Among control group only 7.7% had history of GDM. This result statistically significant p=0.001. 6.9% cases had history of macrocosmic child which was not statistically significant p=0.49. There was no history of still birth or other congenital defect. Mean serum homocysteine level among cases (6.50 ± 1.72) and controls (5.20 ± 1.87) which was statistically significant p=0.001. Positive correlation observed between maternal serum homocysteine level and maternal blood sugar (r=0.209, p=0.005) in this study. Respondents with high homocysteine level have 3.94 times more chance to develop GDM (OR=3.94; 95% CI = 1.59-9.77). Conclusion: Finding from the present study suggests that maternal elevated serum homocysteine level in pregnancy is significantly associated with Gestational Diabetes Mellitus.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121380818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Post Placental Copper T380 A Insertion in Women during Caesarean Section","authors":"Tahasina Shamim, Sheikh Tapaty Tahsin, Ahmed Rezvi","doi":"10.36348/sijog.2023.v06i05.007","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.007","url":null,"abstract":"Objective: The study was carried out to evaluate the outcome of post placental COPPER T380 A insertion in women during caesarean section. Methods: A descriptive quasi-experimental study was carried out to evaluate the outcome of post-placental COPPER T380 A insertion in women during caesarean section. They were interviewed with a specific pre-designed questionnaire Results: The patients were asked to visit 1, 6 and 12 months after the insertion of COPPER T380 A to record the complaints during the follow-up period. It was found that only 2(1.33%) complaints of expulsion after 1 month of insertion and 1 (0.66%) after 6 months, and there was no complaint of expulsion at 12 months of follow-up. In case of PID, there were 3(2%) at 1 month, 1(0.66%) at 6 months and 1(0.66%) at 12 months follow up. The most frequent complaint was pain lower abdomen which accounted for 13 (8.67%), 12 (8.00%) and 8 (12.67%) at 1. 6 and 12 months of follow-up, respectively. The next common complaint was the vaginal discharge of 9 (6.00%) at 1 month, 8 (4.67%) at 6 months and 10 (6.67%) at 12 months of follow-up. No failure of COPPER T380 A insertion during cesarean section within 12 months of follow-up (No pregnancy within 12 months). Conclusion: Clients and providers can benefit from COPPER T380 A's high motivation, low risk of infection, and fast insertion speed when used after childbirth. The use of an intrauterine device as a form of birth control immediately after delivery has been shown to be effective and safe. Furthermore, considering the large number of puerperal who do not return for contraception, the use of a safe contraceptive method, provided quickly after delivery and before discharge from the hospital, is a far-reaching reproductive health strategy.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125331455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Etiology of Urinary Tract Infections among Pregnant Women in a Tertiary Care Hospital- A Prospective Observational Study","authors":"F. Begum, Dipi Barua, Ayesha Nigar Nur","doi":"10.36348/sijog.2023.v06i05.005","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.005","url":null,"abstract":"Introduction: Urinary tract infections (UTIs) are a common health issue among pregnant women, leading to adverse maternal and neonatal outcomes. Despite this, the etiology of UTIs among pregnant women, particularly in resource-limited settings like Bangladesh, is poorly understood. Methods: This prospective observational study was conducted at the Department of Obstetrics and Gynecology, Holy Family Red Crescent Medical College Hospital, Dhaka, Bangladesh. A total of 120 pregnant women with UTIs, admitted between January 2021 and June 2022, were included in the study following specific inclusion and exclusion criteria. Result: The majority of the women was aged 18-24 years (35.83%) and had secondary education (32.50%). Anemia and proteinuria were present in 31.67% and 20.00% of the women, respectively. The primary obstetric characteristic was being primigravida (60.00%). Key risk factors of UTIs included a history of UTI (25.00%), diabetes mellitus (12.50%), frequent sexual activity (33.33%), history of urinary tract abnormalities (8.33%), use of urinary catheters (4.17%), and recent antibiotic use (20.83%). The primary etiological agent was Escherichia coli (60.00%). Conclusion: The findings underscore the need for comprehensive antenatal care, including routine screening for UTIs, anemia, and proteinuria among pregnant women in Bangladesh. Targeted interventions, such as health education and improved sanitation, are recommended to mitigate the identified risk factors. Further research on antimicrobial resistance patterns among the identified etiological agents is warranted to guide appropriate antimicrobial therapy.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122171062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Ferritin and Serum Iron Level in Preeclampsia","authors":"Dilshad Rifaha, N. Akhter, M. R. Rahman, Nusrat Jahan Khan, S. Akter, Yeasmin Dil Jannat, Zhuma Rani Paul, Tashmin Tamanna","doi":"10.36348/sijog.2023.v06i05.004","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.004","url":null,"abstract":"Background: Preeclampsia, gestational diabetes, and premature delivery are three obstetric problems related with high iron reserves during pregnancy. Few studies have found an association between preeclampsia and higher serum ferritin levels, however, this finding was not convincing. Objectives: The aim of this study was to assess the variation in the levels of serum ferritin and serum iron level in preeclamptic Bangladeshi women compared to healthy pregnant women. Methods: This case control study was carried out in the Department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University (BSMMU) during October 2018 to September 2020. A total of 94 pregnant women between 18-40 years of age were included in this study in her 32 weeks to 38 gestational weeks. Among them 47 diagnosed case of preeclampsia and rest 47 healthy pregnant women were consider as control. Purposive sampling technique was followed. After taking consent and matching eligibility criteria, data were collected from patients on variables of interest using the predesigned structured questionnaire by interview, observation, clinical examination and hematological investigation of the patients. The serum ferritin and serum iron level were measured in Department of Biochemistry in BSMMU. Statistical analyses of the results were be obtained by using window based Microsoft Excel and Statistical Packages for Social Sciences (SPSS-22), where required. Results: Serum ferritin in preeclamptic women was (124.54±32.14 ng/ml), versus (50.83±2.53 ng/ml) in the control group with P-value (0.001). Serum iron in preeclamptic women was (110.19±23.62µg/dl), versus (105.15±26.6 µg/dl) in the control group with P- value (0.334). Almost three fourth (74.5%) patients had serum ferritin >120 (ng/ml) in case and 17(36.2%) in control. The difference was statistically significant (p<0.05) between two groups with OR= 5.15 (95% CI 2.12-12.47). There was a positive significant Pearson’s correlation coefficient between serum ferritin and each systolic and diastolic blood pressure (r=0.561, p<0.001 and r=0.556, p<0.001 respectively). Serum ferritin level increases significantly in preeclamptic women. There was no significant difference in serum iron levels between the preeclamptic women and control groups. Increased level of serum ferritin may play a role in pathogenesis of preeclampsia. Conclusion: Preeclampsia as one of pregnancy related complications is a notable burden of adverse health. This case-control study demonstrated that preeclampsia is associated with high serum ferritin levels, and that in preeclamptic women, serum ferritin was positively correlated with blood pressure.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127518413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adnex Torsion Complicating A Dermoid Cyst of the Ovarian Girl: Apropos of 2 Cases in the Pediatric Surgery Unit of the Hospital in Mali","authors":"S. S, T. K, Cissé M C A, K. S, D. K, S. A, M. S, C. B, T. O, C. Y","doi":"10.36348/sijog.2023.v06i05.003","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.003","url":null,"abstract":"Adnexal torsion is a spontaneous rotation of the ovary and sometimes the fallopian tube around its axis which can interfere with arterial supply and lead to ischemia It is a rare complication of an ovarian cyst, which can occur at any age, from the fetal period to adulthood. The mature cystic teratoma accounts for 20% of all ovarian tumors and is seen especially in young girls and therefore is most often benign. It's a surgical emergency. We report here two cases of adnexal torsion operated at the level of the pediatric surgery unit of the Hospital of Mali The two girls are 14 and 13 years old, nulligest and normoregulated with recurrent abdominal pain admitted for acute pelvic pain. On palpation, an abdomino-pelvic mass of a firm and painful consistency is noted. An abdominopelvic ultrasound was performed in both cases and revealed torsion of the left adnexa on the left ovarian cyst in the first and on the right in the second. The surgical procedure performed was manual detorsion and cystectomy in both cases. The anatomopathological examination concluded with a dermoid cyst In the two girls and their postoperative course was simple.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115457736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uterine Conserving Cervical Myomectomy in a Young Nulliparous Woman in Navy Reference Hospital Calabar, Nigeria","authors":"C. Elegbua, Surajdeen Tunde Afolayan, E. I. Archibong, I. O. Eze","doi":"10.36348/sijog.2023.v06i05.002","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.002","url":null,"abstract":"Management of cervical fibroid which is one of the rare sites of uterine fibroid comes with challenges to gynaecologists especially in young nulliparous women where uterine conserving surgery is to be instituted. Cervical fibroid locations can be in the supravaginal or vaginal aspect of the cervix. It can also present as pedunculated fibroid or sessile fibroid from the cervical lip. The commonest presentations of cervical fibroid are pelvic pressure symptoms and menstrual irregularities. This is a case of a 24 year old nulliparous woman with recurrent pelvic pressure symptoms, heavy menstrual flow and vaginal discharge with diagnosis of cervical fibroid and vaginal fibroid polyp and was managed by uterine conserving surgery.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123030501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Inter-Pregnancy Interval on Maternal Serum Ferritin, Haematocrit Level and Fetal Outcome in University of Ilorin Teaching Hospital Ilorin, Nigeria","authors":"C. Elegbua, Surajdeen Tunde Afolayan, Angela Adaku Elegbua","doi":"10.36348/sijog.2023.v06i05.001","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i05.001","url":null,"abstract":"Background: Short inter-pregnancy interval (SIPI) has been linked with low maternal haematological indices and adverse fetal outcome. The World Health Organization (WHO) recommended a minimum of 24 months inter-pregnancy interval to reduce the risk of adverse maternal and fetal outcomes. However, sub-optimal pregnancy spacing is common in many developing countries including Nigeria. Objectives: To determine the impact of inter-pregnancy interval on maternal serum ferritin, haematocrit level and fetal outcome among parturient in University of Ilorin Teaching Hospital, Ilorin, Nigeria. Study Design: A prospective cohort study of parturient less than 20weeks gestation. Those who did not satisfy the WHO recommended inter-pregnancy interval of at least 24months were categorized as group II while gestational age and social status matched parturient who satisfied the WHO recommendation were in group I. Methodology: A total of 316 parturient who satisfied the inclusion criteria were recruited for the study by systematic sampling. These were equal number of 158 participants each as subject and control. Subject and control were matched for gestational age and social status. The serum ferritin and haematocrit levels as well as fetal outcome were evaluated for each participant. The results were analysed using SPSS version 20.0 with appropriate tables and figures generated. Results: There was statistically significance difference in the mean levels of serum ferritin (P<0.001) and haematocrit (P<0.001) at booking for the two groups of participants. There was statistically significant difference in the gestational age at delivery (P<0.001) with higher rate of preterm delivery (22.1% vs. 1.9%; P<0.001) in group II compared to group I. In addition, there were higher percentages of group II babies with 1st (32.5% vs. 9.6%; P<0.001) and 5th minute (18.2% vs. 1.9%; P<0.001) APGAR scores < 7 compared to group I babies (P<0.001). The mean birth weight was lower in group II (2.70±0.35 vs. 3.10±0.31; P<0.001) with higher need for neonatal resuscitation (16.9% vs. 2.6%; P<0.001) and intensive care admission (18.2% vs. 1.3%; P<0.001) among neonates of women in group II. Neonatal anaemia (15.4% vs. 0.0%; P<0.001) occurred only in group II participants’ babies. Neonatal mortality was zero for group I and 18(11.7%) for group II babies. Conclusion: Inter-pregnancy interval below the WHO recommendation is associated with low maternal serum ferritin and haematocrit levels as well as adverse fetal outcome. Recommendations: Adequate child spacing should be emphasized during antenatal visits, postpartum counselling, postnatal clinic visits as well as other contacts with non-pregnant women of reproductive age.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129335573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}