Scholars International Journal of Obstetrics and Gynecology最新文献

{"title":"Comparison the Presence of Serum Level of Albumin, Uric Acid and Creatinine in Pregnant Women Developed Symptoms of Preeclampsia and Who are Free from Symptoms of Preeclampsia: A Prospective Study","authors":"Dr. Khaleda Jahan, Dr. Md. Anwar Hossain Khan, Dr. Nargis Sultana, Dr. Sabina Sharmeen","doi":"10.36348/sijog.2022.v05i12.002","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i12.002","url":null,"abstract":"Background: Preeclampsia, a hypertension condition that develops during pregnancy, is one of the most common causes of premature labour and delivery, perinatal death, and maternal mortality. Preeclampsia and other hypertensive diseases of pregnancy complicate a significant percentage of all pregnancies, necessitating early detection and warning. Objective: The aim of this study is to compare the presence of serum level of albumin, uric acid and creatinine in pregnant women who developed symptoms of preeclampsia and who are free from symptoms of preeclampsia. Method: A prospective study was carried out among 119 pregnant women in the outpatient Department of obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University, Bangladesh, from June 2005 July 2006.Details and data obtained from medical records section were analyzed. Results: Among 119 women, PE developed in 10 patients and 109 patients remain normotensive. Among the study group incidence of PE was 8.4%. The mean age was 25.48±5.26 vs 25.60±3.89 in control vs PE subjects respectively. At booking the mean SBP was 104.40±10.67 vs 121.50±6.26, mean DBP was 65.73±6.41 vs 68.00±5.87, mean MAP was 77.66±5.28 vs 78.62±6.39 respectively in control and PE subjects. The mean serum albumin (gm/dl) of the study groups were as follows: control 2.97±0.55 vs PE 3.73±0.52. Serum creatinine of the study group (0.78±8.5 and 0.79±6.11 in control vs PE) and serum uric acid (2.24±0.71 and 2.65±0.56 in control vs PE) shows no significant difference at booking visit. The sensitivity of S. albumin, uric acid and creatinine area is 50%, 10%, 0%. Specificity of serum albumin is 5.25%, uric acid is 9.09%. But specificity of creatinine is high (97%) positive predictive value of all parameters are low. PPV of serum albumin is 4.76%, serum creatinine is 6.6%. Negative predictive value of creatinine is high (72%). Negative predictive value of serum albumin and serum uric acid are 6.42% and 9.12% respectively. Conclusion: In developing nations, pre-eclampsia is a common cause of maternal and neonatal illness. In maternal serum, many biochemical markers of pre-eclampsia have been identified. Uric acid, creatinine, and albumin are only a few of them. Uncorrelated serum uric acid, serum creatinine, or serum urea readings are insufficient to be considered as reliable predictors of preeclampsia.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134464900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcervical Amnioinfusion in Meconium Stained Amniotic Fluid in the Pregnant Women at Labour and Foetomaternal Outcome Attending Labour Ward of Rajshahi Medical College Hospital","authors":"Dr. Rawshan Akhtar, Dr. Md. Zillur Rahman, Dr. Nazmun Nahar, Dr. Afroza Khatun, Dr. Nasim Parvej, Dr. Anika Ahmed, Dr. Saklayen Ferdous","doi":"10.36348/sijog.2022.v05i11.006","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i11.006","url":null,"abstract":"Background: Amniotic fluid is the fluid present in amniotic sac which surrounds the foetus, provides nutrition and maintains temperature of the foetus. Physically it allows the foetus to move and prevents it from injury. Functionally it enables foetal breathing mobility that prevents pulmonary hypoplasia and exercises digestive tract by swallowing amniotic fluid. Objective: The objective of the study was to explore the role of amnioinfusion in intrapartum management of meconium stained amniotic fluid in the pregnant women at labor and foetomaternal outcome of the patients attending labor ward of Rajshahi Medical College Hospital. Methods: This experimental randomized control trial study carried out in the Department of Obstetrics and Gynecology of Rajshahi Medical College Hospital, Rajshahi from July, 2012 to June, 2014. Sample size was 100 and randomly allocated into equally two halves as study group and control group. Purposive sampling technique was followed. Results: In this study the age of the study group up to 30 years was 38(47.5%), control group 42(52.5%) and total 80(80.0%). On the other hand, in >30 year’s study group was 12(60.0%), control group 8(40.0%) and total 20(20.0%) respectively. and that of control group was 26.24 (±4.75) years. The mean age of the study group was 27.44 ± 5.59, control group was 26.24 ± 4.75 and total was 26.84 ±5.18 years. The mean weight of the study group was 66.84 (±3.25) kg and in the control group 62.64(±2.84) kg. In this study, 96.0% of the respondents had normal vaginal delivery and among them, 52.1% were in the study group and 47.9% in the control group. On the other hand, only 4% of the respondents had lower segment caesarean section and all of them were in the control group. The mean gestational age at delivery of the respondents in the study group was 39.88 ± 0.78 weeks and in the control group 39.84 ± 0.75 weeks. Conclusion: In this study Tran’s cervical amnioinfusion gave positive result by providing reducing picture of operative delivery in study group. There was significant difference in respiratory distress in the baby having lower percentage in the study group. A large scale study should be carried out to make the result of this study a reliable one.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134469142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indication of Induction of Labor-A Hospital Based Study","authors":"Dr. Ferdousi Begum, Dr. Nargis Sultana, Dr. Yasmin Ara Begum, Dr. Hachina Akhter, Dr. Mosammat Rehana, Dr. Karishma Sultana, Dr. Sunny Barua, Dr. Nasrin Zannat Sumi","doi":"10.36348/sijog.2022.v05i11.004","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i11.004","url":null,"abstract":"Introduction: Labor induction is the technique that excites childbirth and vaginal delivery. Inducing labour can be built with the pharmaceutical or non-pharmaceutical method. In low-income countries, the rates are generally minor. IOL is not risk-free, and many women find it painful. Aim of the Study: The study aims to investigate the indication of induction of labour. Methods: A Prospective cross-sectional study was carried out in the Department of Obstetrics & Gynecology, Bangabandhu Sheikh Mujib Medical University, Hospital, from January 2008 to June 2008. A total of 50 patients were enrolled in this study following the inclusive criteria. Data were collected using the predesigned semi-structured questionnaire. Verbal consent was taken before recruiting the study population. Completed data forms were reviewed, edited, and processed for computer data entry. Result: Among the study population (N=50), one-fifth of the mothers’ (10,20.0%) age was under twenty. The majority of mothers were (34,68.0%) between 20-30 years old with a mean age of 25.4 ± 4.32 years. In seventeen patients (17,34.0%) labour induction was given by oxytocin drip followed by ARM, in ten patients labour induction was given by ARM followed by oxytocin drip & in twenty-three patients (23,46.0%) with unfavourable cervix prostaglandin was used and then followed by oxytocin drip and ARM. The total number of induction failures (who needed a caesarian section) was twenty (20,40.0%). Among the total number of caesarian sections, eleven (11,55.0%) were done due to fetal distress, nine (9,45.0%) were done due to abnormal uterine action, one (1,5.0%) was done due to cervical dystocia. Conclusion: Labor induction should be applied to improve birth consequences and when the potential aids outweigh the potential dangers. Researches point out that inducing labour lessens the risk of having a stillbirth, macrosomia and developing high blood pressure as the pregnancy advances.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129278831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Survey on Prevalence, Interventions, and Outcomes of Unsafe Abortions in GGH, Kadapa","authors":"Dr. Bukkittu Ramya, Dr. B.V. Chitra Ravali, Dr. Rabbani Begum","doi":"10.36348/sijog.2022.v05i11.002","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i11.002","url":null,"abstract":"Objective: Unsafe abortions among the various age groups of women due to unintended pregnancy and socio- economic constraints have a deleterious effect on their reproductive and mental health. Hence, review and modification of safe abortion practices are crucial, owing to the rampant availability of over-the-counter MTP kits and D&C by unskilled professionals resulting in Maternal Mortality and Morbidity. This study provides an estimate of the outcomes of unsafe abortions. Methods: WHO [1] defines unsafe abortion as the termination of a pregnancy by people lacking the necessary skills, or in an environment lacking minimal medical standards, or both. The present study is a cross-sectional descriptive analysis of outcomes of unsafe abortions at a tertiary care center, GGH Kadapa. The study data includes all the women admitted to the emergency obstetric unit and treated for unsafe abortions between January 2019 to June 2020. Age group of the selected population is between 15-45. The sample included 342 cases of recent induced abortions. The primary outcome of the study is to emphasise the burden, causes, setting and the morbidity of unsafe abortions. Results: Total number of deliveries that occurred between Jan 2019 to June 2020 is 13787 and the total number of induced abortions during this period was 342. Out of which, 211(61.7%) were unsafe abortions. Among them, 53 women (25.11%) presented with shock. 89 women (42.1%) needed blood transfusions. 8 (3.79%) women went into DIC. One woman had a uterine rupture, and underwent uterine rent repair. Four women had uterine perforation with associated bowel injury. Bowel repair was done in 1 case, and a colostomy was required in 3 cases. Emergency laparotomy was performed in these 5 cases. Conclusion: Unsafe abortions are one of the leading causes of maternal mortality and morbidity in a developing country like India. This is mainly attributed to socio-economic constraints, poor awareness of contraception, and cultural beliefs against sterilization forcing the pregnant women to indulge in unsafe abortion practices. Creating contraception awareness in reproductive age group, strict laws against unsafe abortion practices are to be implemented to reduce the maternal morbidity and mortality due to unsafe abortions.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125191607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetomaternal Outcome of Patients with Multiple Pregnancy: A Single Centre Experience","authors":"Dr. Salma Akhter, Mohibul Islam, Latifa Zaman, Sk Tasnuva Alam, Ferdous Ara Banu","doi":"10.36348/sijog.2022.v05i11.003","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i11.003","url":null,"abstract":"Background: Multiple pregnancies are prone to be associated with adverse maternal and perinatal outcome. The incidence of multiple pregnancies has shown a significant increase over the last decades. Aim of the Study: This study aimed to describe the maternal and perinatal outcomes in multiple pregnancies delivered in a tertiary care hospital, Bangladesh. Methods: This was a prospective observational study; 23 patients were enrolled and analyzed. The study conducted with 23 women with twin pregnancies, over 2 year’s months from January 2020 December 2021 in the department of Gynecology and Obstetrics, Chittagong Medical College and Hospital, Chittagong, Bangladesh. Result: Out of 23 cases, 8 patients had intrapartum complications like PPH, mal-presentation, cord prolapse, low-lying placenta, and placental abruption. In this, 4(23.53%) had mal-presentation, and only one had PPH. These intrapartum complications were also categorized according to their chronicity. Mal presentations were seen in 23.53% of DCDA and 33.3% of MCDA with p=0.47. Both were not statistically significant, as shown in Table 4. These twin-specific complications were noted according to their chronicity. Discordant twin was seen in 11.76% of DCDA and 16.67% MCDA. Single IUD in 7.9% of DCDA. The complications and outcomes of the study population; more than 65% of patients needed NICU. In our study, we noted 4 perinatal death caused by intrauterine death, twin-to-twin transfusion syndrome, birth asphyxia, and respiratory distress. Conclusion: Majority of the multiple pregnancy is high risk one. So, all multiple pregnancies need early diagnosis, adequate antenatal, intra-natal and post-partum care to improve the outcome and should have mandatory hospital delivery.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131468101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Vesicovaginal Fistulas in Sylhet MAG Osmani Medical Hospital: A Two Years Study","authors":"Dr. Umme Sayeeda Bilkish, Dr. Rabeya Begum, Dr. Suraiya Apsara, Dr. Jafrin Yasmin","doi":"10.36348/sijog.2022.v05i11.001","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i11.001","url":null,"abstract":"Background: Vesico-vaginal fistula (VVF) is still a persisting scourge in the developing countries with devastating medical and social consequences. These consequences were studied among patients presenting with vesico- vaginal fistula in Sylhet MAG Osmani Medical College Hospital, Sylhet. Objectives: To analyzethe vesico-vaginal fistula patients during the 2 years period. Materials and Methods: This was a descriptive and cross-sectional study conducted in the Department of Obstetrics and Gynaecology, Sylhet M.A.G. Osmani Medical College Hospital, Sylhet from May 2008 to April 2010 (2 years).Fifty-three hospitalized patients with vesico-vaginal fistula were selected by Inclusion and exclusion criteria, undergoing repair operation irrespective of age. After selection of the patients informed written consent was taken. Each patient was interviewed using the semi-structured questionnaire containing socio- demographic and other relevant information like age, occupation, education of the patient and her husband, age at marriage, age at 1* child birth, monthly income and detailed history of the delivery. Type of fistula and related examination of the fistula was also done and noted. Type of repair of vesico-vaginal fistula, postoperative complications and outcome was recorded in the same manner. Results: The mean age of the patients with vesico-vaginal fistula was 30.5 years (SD± 8.5; range, 18 to 52). Majority (73.6%) were between 21 to 40 years; and 52.8% patients were primipara, 81.1% patients were illiterate and 69.8%patientswere from lower social class. The aetiology of fistula were obstructed labour 49.1%, emergency lower segment caesarean section 37.7%, destructive delivery 11.3% and caesarean hysterectomy 1.9%.The repair operation was done of all patients in this series through vaginal approach. Repair was done first time in 83% and rest had history of failed repair. Postoperative complications were catheter block and urine leakage in 37.7% and urinary tract infection in 11.3% patients. Successful outcome was found in 79.2% cases. Causes of failure were severe scaring 36.5% difficult operation, catheter block and others each constituted 18.2% and large fistula 1.9%. Conclusion: Young primi are the victims of vesico-vaginal fistula, obstetric causes add up to form a major share of the etiology of vesico-vaginal fistula. Proper perinatal management is most important to reduce obs fistula formation.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128697384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension as a Risk Factor for Adverse Neonatal and Maternal Outcome","authors":"Dr. Farhana Afroz Chomon, Dr. Abu Sayeed Md Mortoza, Dr. Tamzima Siddique","doi":"10.36348/sijog.2022.v05i12.001","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i12.001","url":null,"abstract":"Introduction: During the period of pregnancy, many physical and social activities can become of great risk to the fetal and maternal outcome. Among the many physical ailments that have an effect on maternal and fetal outcome, hypertension and diabetes are the most common cause, and effects. During diabetes, maternal hypertension and gestational diabetes can occur, and can cause great changes to the outcome of pregnancy. The present study was conducted among all hypertension patients to see the different types of hypertension and their incidence rate among pregnant women, and their maternal and fetal outcomes at pregnancy. Methods: This descriptive cross-sectional study was conducted at the Department of Gynecology, Kushtia 250 bed General Hospital, Kushtia, Bangladesh. The study duration was 1 year, from January 2020 to January 2021. During this period, a total of 100 cases of hypertensive pregnancies visiting the study place were admitted following the inclusion and exclusion criteria. Result: Majority of the hypertensive mothers had been between the ages of 21-25 years, while mean birth weight was below normal range among the neonates. Moderate preeclampsia had the highest prevalence among the mothers, and anemia and nulliparity were observed in 67% and 44% respectively as risk factors among the participants. Adverse perinatal outcome had a significantly high prevalence among neonates of preeclampsia groups. Conclusion: The study observed higher incidence of preeclampsia among pregnant women, and adverse perinatal outcomes had significant rise among preeclampsia cases. Anemia was the most common risk factor for hypertension in the present study, followed by Nulliparity. Adverse maternal outcomes did not have a significant association with type of hypertension, but seizure and oliguria were more common among preeclampsia cases.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117031096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of “Uterine Artery Doppler” at 11 to 13+6 Weeks for Prediction of Preeclampsia: A Systematic Review","authors":"Dr. Shazia Rasul, Dr. S. M. Shahnawaj Tahir, Dr. Miriam Illa","doi":"10.36348/sijog.2022.v05i10.011","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i10.011","url":null,"abstract":"Objective: This systematic review is aimed to review the role of uterine artery Doppler in first trimester of pregnancy along with use of maternal characteristics as a predictor of early and late on set pre-eclampsia (PE). Selection Criteria: The search was limited by selecting; only original articles, prospective & retrospective study designs, role of uterine artery Doppler done at 11 to 14 weeks, done on singleton pregnancy and written in English language were included. Data Collection and Analysis: The data extracted for author name, year of publication, place of study, duration of study, study design, outcomes and study variables including maternal factors, uterine artery Doppler and serum markers. Then detailed analysis of uterine artery Doppler performance as predictor in the form of Area under curve, Sensitivity, Specificity, Positive predictive value, Negative Predictive Value and its relation to preeclampsia, Early PE and Late PE. Results: Following the search strategy of PRISMA, 148 full articles reviewed, and 21 articles were included from 2010 to 2021. Out of 21 articles, 19 articles had “prospective study design” whereas two had “retrospective. Out of 21 researches, 15 assessed early preeclampsia, 4 assessed late preeclampsia, 4 assessed both, however 7 articles studies only preeclampsia as an outcome. The extracted estimate show value of first trimester uterine Doppler as a predictor of early and late preeclampsia. Conclusions: The uterine artery Doppler with maternal characteristics is a valuable, noninvasive tool to be used at 11 to 14 weeks as predictor of preeclampsia in the low resource settings where serum markers cannot be available to general population.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130027158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Association of Serum Magnesium with Preterm Labour","authors":"Dilruba Ferdous, Dr. Mousumi Kader, Dr. Rogina Amin, Dr. Shahana Rahman, Dr. Rabeya Sultana Jolly, Dr. Sayada Fatema khatun, Dr. Rushdana Rahman Toma, Dr. Zinat Ara Ferdousi, Dr. Lutfa Begum Lipi","doi":"10.36348/sijog.2022.v05i10.012","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i10.012","url":null,"abstract":"Background: Magnesium plays an import role in the physiology of parturition. Decrease of Magnesium in plasma may be responsible for a decrease of the same in myometrium and this might have a considerable influence on the preterm labour. A Hypomagnesaemia leads to neuromuscular irritability leading to uterine hyperactivity which leads to cervical dilation. Objective: To find out the association between serum magnesium and preterm level. Methods: This was a cross sectional study, conducted in 100 women in labour, of them 50 were diagnosed case of preterm labour and 50 women were in labour at term attended in Gynaecology and Obstetrics department of Dhaka Medical College, Dhaka, from January 2015 to December 2015.5ml fasting blood sample was collected and was analyzed for serum magnesium using a standard enzymatic method. The mean value of serum magnesium was compared between two groups by student unpaired t-test and serum magnesium level was correlated with BMI, Gravita and gestational age in preterm labour patients by Pearson’s correlation coefficient test. A p-value was considered to be statistically significant at 0.05 at a 95% confidence interval. Results: The mean age was found 28.2±4.5 years in group I and 26.7±4.1 years in group II. The mean age difference was not statistically significant (p>0.05) between two groups. A majority (80.0%) of the patients came from a middle-class family in group I and 29(58.0%) in group II. The mean BMI was found 23.0±3.8 kg/m2 in group I and 26.4±2.4 kg/m2 in group II. The socioeconomic status and BMI were statistically significant (p<0.05) between two groups. The mean serum magnesium was found 1.64±0.13 mg/dl in group I and 2.05±0.11 mg/dl in group II. The mean serum magnesium level was significantly (p<0.05) lesser in group I. Serum magnesium had an area under curve 0.974, which gave a cut-off value < 1.8 mg/dl, with 98.0% sensitivity and 88.0% specificity for prediction of preterm labour. Conclusion: Most of the patients were belonged to age 21-30 years in both groups are not associated. A negligible correlation was found with BMI, gravid, through serum magnesium in preterm labour. Low serum magnesium level was significantly higher in preterm labour.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123082909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relation Between Labetalol and Methyldopa in Treatment of Pregnancy Induced Hypertension","authors":"Layla Khayrun Nahar, N. Haque, A. Kutubi, Ratu Rumana, Shikha Gangoly, S. Akhter, Nowshin Yesmin Tonny, Saira Elaine Anwer Khan","doi":"10.36348/sijog.2022.v05i10.010","DOIUrl":"https://doi.org/10.36348/sijog.2022.v05i10.010","url":null,"abstract":"Background: Hypertensive disorder is the most common medical problem encountered in pregnancy with a high perinatal and maternal mortality & morbidity. Worldwide about 76,000 pregnant women die each year from preeclampsia and related hypertensive disorders. Objective: To assess the relation between labetalol and methyldopa in treatment of pregnancy induced hypertension. Methods: This study was hospital based comparative prospective study was conducted at Dept. of Obstetrics & Gynaecology, Dhaka Medical College Hospital, Dhaka, Bangladesh from January to June 2021. The study consisted of 100 patients with pregnancy induced hypertension attending outpatient department and admitted in ANW, or who directly came to labour room. These patients were randomly selected on lottery basis after they fulfilled the inclusion criteria. Total patients were taken for the study and divided into 2 groups of 50 patients in each group. Results: A total 100 patients were included. The mean age in Group I was 24.4±4.55 years and in Group-II, 23.95±4.28 years. Maximum number of patients was between 19- 24 years in both the groups. In Group-I, 26 (52%) patients and in Group-II, 25 (50%) patients were in this age group. The maximum age in the Group I was 34 years and 35 years in the Group-II. The minimum age was 17 years in both the groups. The inter group difference was not statistically significant (p>0.05) thus the two groups were comparable by age. At baseline no significant difference was seen in SBP in both treatment groups. However after 8 days post testament SBP of women was significantly lower in Group-I patients as that of Group-II patients. i.e. Group-I: 123.41 vs. Group-II: 126.62, p- value=0.009. At baseline no significant difference was seen in DBP in both treatment groups. However at 8th day post treatment DBP of patients was significantly lower in Group-I patients. i.e. 77.18 vs. Group-II 79.64, p-value=0.005. For SBP more effective control was seen in women whose parity was 3-4 and for DBP notable difference was seen in women whose parity was 1-2. The control of systolic blood pressure was more effective in patients with normal body mass index and for Diastolic blood pressure (DBP) more effective control was seen in patients who were obese. On comparison methyldopa significantly causes more drowsiness, headache and nasal congestion and the incidence of Postural hypotension and dysponea in both groups were not significantly different. The patient who required additional drugs to control the uncontrolled hypertension. In Group I, 2 (4%) patients and in Group II, 3 (6%) patients did not respond with starting drug. The inter group difference was not statistically significant (p>0.05). Conclusion: Labetalol had less maternal adverse effect compared to methyldopa but fetal outcome was not observed in this study. Labetalol and methyldopa are equally efficacious in controlling blood pressure in new onset hypertension in pregnancy. This study is just a step in thi","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115557626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}