Scholars International Journal of Obstetrics and Gynecology最新文献

{"title":"Clinical Presentation and Histological Types of Ovarian Tumor in Patients Admitted in Tertiary Care Center","authors":"Roksana Haque, Tasnuva Akter","doi":"10.36348/sijog.2023.v06i11.004","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i11.004","url":null,"abstract":"Background: Ovarian cancer is the eighth most frequent cancer among women worldwide, accounting for 4% of all cancers in the female population. When compared to other reproductive system cancers, ovarian cancer has a high death and morbidity rate. Objectives: The aim of the study was to assess the clinical presentation and histological types of ovarian tumor in patients admitted in tertiary care center. Methods: A descriptive cross-sectional study was conducted to determine the clinical presentation and histopathological types of ovarian tumour diagnosed at Medical college for women, Uttara and Nightingale medical college, Ashulia. The study was approved by the Institutional Review Board (IRB) and 600 patients diagnosed with ovarian tumors were consecutively included in the study from July 2009 to August 2016. The cases were diagnosed and subclassified in accordance with the WHO Classification of Female Genital Tumours, Fourth Edition. Statistical Package for Social Sciences (SPSS) application, version 25, was used for data analysis. Results: Out of Total Gynaecological admission of 4800 patients during the study period, 600 patients were admitted with diagnosis of ovarian Tumor, So occurance was 12.5%. the mean age of the patients was 35 ± 2.09. About 8.6% of the patients had less than 20 years old. 56.6% were within the age group of 21-40, 29.8% were within the age group of 41-60 and only 5% had more than 60 years. The mean Menarche in years was 14.6 ± 1.02 and Menopause in years was 48.7 ± 2.46. Regarding clinical presentation 37.40% had abdominal pain, 55.50% had abdominal mass, 3% had abdominal distension,2% had ascites, 0.50% had menstrual irregularities and 2.50% were asymptomatic. Regarding surgical procedure, 35% undergone Total abdominal hysterectomy and bilateral salpingo-oophorectomy, 18.33% Bilateral salpingo-oophorectomy, 15% Right salpingo-oophorectomy and Left salpingo-oophorectomy recommendation, 13.33% Right cystectomy, 3.33% Left cystectomy. Regarding consistency of tumour 57.33% were cystic, 37% were solid, 5.33% were complex and 0.33% were Diffuse pattern (metastatic tumor). Benign tumors were 77%, borderline 16.67% and malignant 6.33% cases. Out of 462 benign tumors, Serous cystadenoma (230/49.78%), Mucinous cystadenoma (60/12.98%), benign Brenner tumor (10/2.16%), Mature cystic teratoma (110/23.80%), stroma ovarii (10/2.16%), Fibroma (10/2.16%), Fibro-thecoma (12/ 2.59%), leiomyoma (20/4.34%). Out of 38 malignant tumour, Serous cystadenocarcinoma (11/28.94%), mucinous cystadenocarcinoma (6/15.78%), clear cell carcinoma (1/2.63%), Malignant Brenner tumor (1/2.63%), endometroid adenocarcinoma (4/10.52%), squamous cell carcinoma arising in mature teratoma (1/2.63%), Dysgerminoma (7/18.4%), Immature teratoma (1/2.63%), malignant mixed germ cell tumor (1/2.63%), Adult granulosa cell tumor (4/10.52%), Krukenburg tumor (1/2.63%). Survival status was satisfactory; 99.67% patients was alive. Conclusion: The study found that ovarian ","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"12 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139268248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal Outcome in High-Risk & Severe-Risk Pregnancy- A Study in a Tertiary Care Hospital","authors":"Afroza Sultana, Rina Haider, Kulsum Akhter, Shamsad Begum","doi":"10.36348/sijog.2023.v06i11.003","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i11.003","url":null,"abstract":"Introduction: High-risk & severe-risk pregnancies are characterized by increased risks of complications for both the mother and the fetus, which can result from several factors such as maternal age, medical situations, lifestyle habits, and previous pregnancies. These complications are a major concern, mostly in developing countries like Bangladesh, where maternal and infant mortality rates remain high. Maternal complications associated with high-risk and severe-risk pregnancies may include maternal death, severe bleeding, sepsis, and hypertensive disorders, while fetal complications may include preterm delivery, fetal growth restriction, and stillbirth. The objective of this study was to investigate the perinatal outcomes of high-risk and severe-risk pregnancies. Methods: This prospective purposive study was carried out on the admitted patients in the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from July 2007 to December 2007. Total hundreds of risk groups pregnant women (N=100) were enrolled in the study among them eighty-five (n=85) scoring 3-6 included as high risk pregnancy and fifteen (n=15) scoring 7 or more included as severe-risk pregnancy. All relevant data were recorded for each individual study subject on predesigned data collection sheet. All collected data were compiled and analyzed by computer-based statistical software (Instat). Chi-square tests were performed to compare the prevalence of study variables where, p < 0.05 considered the level of significance with 95%CI. Ethical clearance of this study was obtained from the Institutional Review Board (IRB) of BSMMU, Dhaka, Bangladesh. Results: In the high-risk group (n=85), around one-fourth of the patients (22,25.9%) and in a severe- risk group (n=15), one patient (1,6.7%) underwent vaginal delivery, Caesarean section was done in sixty-three patients (63,74.1%) in high-risk pregnant women and fourteen patients (14,93.3%) in severe-risk pregnant women respectively. The distribution of risk group and mode of delivery is statistically highly significant (P <0.001). Out of sixty-three patients (n1=63), nineteen (19, 30.2%) were required to be delivered by caesarean section for fetal distress and fifteen (15, 30.16%) were malpresentation. Out of forty-one patients (n2=14), the most common indications were a history of previous caesarean section with multiple risk factors in eight patients (8, 57.1%). Birth asphyxia was present in nine neonates (9, 13.6%) in a high-risk group (n = 65) and a severe- risk group (n2=14), and birth asphyxia was present in five neonates (5, 35.7%). Based on the outcome, in high-risk pregnancy (n=85), four neonates (4, 4.5%) died and in severe-risk pregnancy (n=15), one (1, 6.3%) died. Conclusion: The study found various obstetric complications and outcomes associated with high-risk and severe-risk pregnancies. The results indicated a significantly higher proportion of caesarean sections performed in seve","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"22 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139277426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nipple Paget's Disease Revealing a CIS and an Underlying Infiltrating Carcinoma about a Case and Review of the Literature","authors":"Y. S, Fdili, A. F. Z, J. S, C. H, M. M. A","doi":"10.36348/sijog.2023.v06i11.002","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i11.002","url":null,"abstract":"We report in this article the case of a patient treated for nipple Paget's disease and in whom clinical and radiological investigations found the association of Paget with carcinoma in situ and infiltrating carcinoma of the breast. Paget's disease of the nipple is a rare variant of CIS. It is associated with an underlying breast adenocarcinoma in more than 80% of cases. Its research must be systematic in imaging, namely MRI. The management of Paget's disease depends on whether or not it is associated with carcinoma in situ or invasive carcinoma. Through our case and in the light of the review of the literature, we insist on the particularity of the positive and differential diagnosis of this entity as well as the therapeutic side, the good knowledge of which allows practitioners to make the diagnosis in time and therefore to improve the prognosis of these young patients.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139282553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Menopause with Lipid Profile: A Study at World College of Medical Sciences and Research, Jhajjar, Haryana","authors":"Geeta Rustagi, Himanshi Rustagi, Ritu Bawa","doi":"10.36348/sijog.2023.v06i12.002","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i12.002","url":null,"abstract":"Background: Menopause induces hormonal changes, including decreased estrogen levels, which can impact lipid metabolism and increase the risk of cardiovascular diseases in women. Objective: This comparative observational study aimed to assess the correlation between menopause and lipid profiles in women aged 35-65 years attending the General Health Check-up OPD at World College of Medical Sciences and Research in Jhajjar, Haryana, India, from January 2020 to December 2022. Methods: A total of 252 apparently healthy women, divided into premenopausal (n=126) and postmenopausal (n=126) groups, were included. Lipid profiles, including total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and very-low-density lipoprotein cholesterol (VLDL-C), were measured. Data were statistically analyzed using an independent t-test with significance set at p < 0.05. Results: In the study of 126 postmenopausal women, mean lipid profiles demonstrated notable values: total cholesterol (TC) at 191.59±35.78 mg/dl, triglycerides (TG) at 143.44±72.39 mg/dl, high-density lipoprotein cholesterol (HDL-C) at 45.01±9.99 mg/dl, low-density lipoprotein cholesterol (LDL-C) at 116.43±31.79 mg/dl, and very-low-density lipoprotein cholesterol (VLDL-C) at 28.69±14.48 mg/dl. Among 128 premenopausal women, mean lipid profiles were: TC 164±35.03 mg/dl, TG 125.52±65.84 mg/dl, HDL-C 41.66±7.66 mg/dl, LDL-C 96.95±31.78 mg/dl, and VLDL-C 25.10±13.17 mg/dl. Postmenopausal women exhibited significantly higher TC, TGs, LDL-C, and VLDL-C, alongside elevated cardiac risk ratios (TC/HDL and LDL/HDL), compared to premenopausal women Postmenopausal women displayed significantly higher mean levels of TC, TG, LDL-C, and VLDL-C compared to premenopausal women. Additionally, cardiac risk ratios, TC/HDL and LDL/HDL, were elevated in the postmenopausal group. Surprisingly, HDL-C levels were also significantly higher in postmenopausal women. Conclusions: Menopause is associated with unfavorable alterations in lipid profiles, including increased TC, TG, LDL-C, and VLDL-C, along with elevated cardiac risk ratios. However, HDL-C levels were unexpectedly higher in postmenopausal women. These findings underscore the importance of monitoring lipid profiles during the menopausal transition to address cardiovascular health concerns effectively.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139291038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic Profile, Causes and Methods of Induced Abortion in a Tertiary Care Hospital, Dhaka, Bangladesh","authors":"Elora Yasmin, Qumrun Nessa Ahmed, R. Sultana, Saima Yeasmin Eva, S. Rouf, Lima Shampa","doi":"10.36348/sijog.2023.v06i08.004","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i08.004","url":null,"abstract":"Introduction: Induced abortions are those terminated by deliberate action undertaken to terminate a pregnancy. Information on the incidence of induced abortion is crucial for identifying policy and programmatic needs aimed at reducing unintended pregnancy. Because unsafe abortion is a cause of maternal morbidity and mortality, measures of its incidence are also important. This study aimed to analyze the sociodemographic characteristics of induced abortion. Methods: A descriptive cross-sectional study was conducted at the Department of Obstetrics and Gynaecology, Dhaka Medical College Hospital, Dhaka, Bangladesh. The sample was composed of 50 women who underwent induced abortion in this hospital, between January 2022 and January 2023. A simple random sampling technique was used in this study. Data were collected using a data collection sheet, processed, and analyzed by SPSS. version 22. Data were presented in tables and pie charts. The study was approved by the Ethics Committee of Dhaka Medical College Hospital. Informed written consent was taken from the respondents. Result: In this study, most of the patients (25, 50%) were in the 25-30 years age group, followed by (18, 36%) 31-35 years age group, and (7, 14%) the rest were in >35 years age group, most people (30, 60%) resided in the urban areas and most of them (35, 70%) had a monthly income of <15000 BDT, followed by (10, 20%) 15000-20000 BDT. Respondents were mostly (25, 50%) uneducated, some of them (15, 30%) passed secondary school, and (10, 20%) higher secondary school. Most of the patients (18, 36%) in this study used the barrier method for contraception, followed by (16, 32%) withdrawal method. Regarding the cause of induced abortion, unplanned pregnancy was the prominent cause (16, 32%), followed by, inadequate income (12, 24%), and contraception failure (12, 24%). Conclusion: This study concluded that most of the patients aged between 25 to 30 years and most of them resided in urban areas having a low monthly income, and poor education level. Some prominent causes of induced abortion were unplanned pregnancy, inadequate income, and contraceptive failure.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"263 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134150385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Vein Thrombosis during Pregnancy and At the Puerperal Period: Radio-Clinical and Therapeutic Study","authors":"Yacoubi Khebiza, S, M. A,, Fdili, A. F. Z, J. S, C. H","doi":"10.36348/sijog.2023.v06i08.003","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i08.003","url":null,"abstract":"Cerebral thrombophlebitis gravidopuerperale is a rare but serious pathology that can engage the maternal-fetal prognosis. It requires early diagnosis and treatment fast. Indeed, much rarer than arterial thromboses, thrombophlebitis are a significant cause of death and stroke. They can occur during pregnancy but most often they occur within a few days to a few months following postpartum. The frequency of peripartum cerebral thrombophlebitis is on average 1/3000 to 1/10000 births, but recently the number of cases recognized seems higher partly because of the more widespread knowledge of the variability of different forms of clinical presentations of cerebral venous thrombosis allowing a diagnosis, and on the other hand the wider use of imaging means more and more effective, in particular MRI. The objective of this study is to describe the epidemiological, clinical, paraclinical, therapeutic and evolutionary gravido -puerperal cerebral thrombophlebitis.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134273615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Adverse Effects of Carbetocin Administration in the Third Stage of Labor","authors":"M. Jahan, F. Ashraf, Shah Mohammad Ashek, Uddin Bhuiyan","doi":"10.36348/sijog.2023.v06i08.005","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i08.005","url":null,"abstract":"Introduction: The pharmacologic agents currently used routinely to prevent postpartum hemorrhage are mainly oxytocin, syntometrine (a combination of oxytocin and ergometrine), and carbetocin. Syntometrine is associated with a statistically significant reduction in the risk of postpartum hemorrhage when compared with oxytocin alone. So, this study aimed to assess the adverse effects of carbetocin administration in the third stage of labor. This study aimed to analyze the adverse effects of carbetocin administration in the third stage of labor. Methods: This cross-sectional observational study was conducted at the Department of Obstetrics and Gynaecology, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh. The study period was from May 2016 to October 2016. 100 women undergoing normal vaginal delivery were the study subject. A convenient sampling technique was used in this study. Necessary data was collected in the data collection sheet. Women received a bolus of 100 microgram carbetocin IV at delivery of the anterior shoulder. A standardized deliver mat (Quaiyum's mat) was used before placental removal for measuring blood loss. Statistical analysis was carried out by using the Statistical Package for Social Sciences version 19.0 for Windows (SPSS Inc., Chicago, Illinois, USA). The mean values were calculated by frequencies and percentages. Result: In this study, the majority (54, 54.0%) of patients belonged to age 20-25 years, followed by (30, 30.0%) >25 years. It was observed that the majority 93(93.0%) patients had regular menstrual history. Concerning the clinical indices, anaemia was found 69(69.0%), jaundice 08(8.0%) and edema 24(24.0%). Additional uterotonices was used in 15(15.0%) and blood transfusion 07(7.0%) patients. Mean blood loss before the use of the weight of Q-mat was found 74.81±1.23 gram, mean blood loss after the use of the weight of Q-mat was 246.28±99.98 gram, and mean net blood loss was 141.61±59.93 gram. Majority 61(61.0%) babies had birth weight ≥2.5 kg. Majority 68(68.0%) patients had Hb% <10.5. The mean Hb% before delivery was 10.3±0.47 gm/dl with a range from 9.40 to 11.20 gm/dl The mean birth weight was found 2.57±0.41 kg with a range from 2.3 to 3.10 kg. Conclusion: Carbetocin appears to be an effective new drug in the active management of third-stage labor. Carbetocin has associated with a lower risk of various adverse effects and preventing postpartum hemorrhage in women undergoing vaginal delivery.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128706572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Preoperative Neutrophil to Lymphocyte Ratio in Patients with Epithelial Ovarian Tumor","authors":"Shahana Rahman, S. Khatun, Dilruba Ferdous, Nazneen Choudhury, T. Nazneen, Reeta Rani Sarkar, Jannatul Ferdous","doi":"10.36348/sijog.2023.v06i08.006","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i08.006","url":null,"abstract":"Objective: Ovarian cancer is a leading cause of gynecological cancer death among women worldwide. Silent growth of the tumor and challenges associated with preoperative evaluation of an ovarian mass are responsible for late presentation. The aim of this study was to evaluate the association between preoperative neutrophil to lymphocyte ratio (NLR) and epithelial ovarian tumor. Methods: A total of 60 patients diagnosed with ovarian tumor who fulfilled the selection criteria were recruited as study population. The ovarian tumor was subsequently diagnosed by histopathological analysis as either malignant epithelial ovarian tumor or benign epithelial ovarian tumor. Preoperative demographic and laboratory variables are reviewed in all patients. Association of preoperative NLR was assessed in benign and malignant epithelial ovarian tumor using unpaired t test. Receiver operating characteristics curve was used to calculate optimal cut off value for NLR to predict ovarian cancer preoperatively. A p-value of <0.05 was considered to indicate statistically significant differences. Results: There was statistically significant difference between the groups in terms of age, menopausal status, and NLR (all p=0.001, except for menopausal status p=0.007). NLR value was significantly higher (3.47±1.52) in patients with malignant ovarian tumor (p=0.001) than that of benign ovarian tumor. Higher NLR value predicted ovarian cancer at the cut-off value of 2.78, with 75.6% sensitivity and 78.9% specificity (95% CI, 0.97-1.0). Conclusion: Malignant epithelial ovarian tumor is associated with higher NLR. Preoperative NLR may be helpful for prediction of malignant ovarian tumor.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"757 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123280808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors Associated with Preeclamptic Women: A Case- Control Study in Dhaka Medical College and Hospital (DMCH)","authors":"R. Sultana, Elora Yasmin, Saima Yeasmin Eva, Lima Shampa","doi":"10.36348/sijog.2023.v06i08.002","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i08.002","url":null,"abstract":"Introduction: Preeclampsia, a dangerous condition characterized by high blood pressure during pregnancy, poses risks to both mothers and infants. Understanding the risk factors associated with preeclampsia is essential for effective prevention and management. This study aims to identify and investigate the potential risk factors contributing to preeclampsia in women, with the goal of improving the health outcomes of expectant mothers and their babies. Methods: This study was a case-control study conducted in the department of Obstetrics and Gynaecology at Dhaka Medical College Hospital (DMCH). The study period spans from 1st July 2019 to 31st December 2019. The study population consists of 100 participants, including 50 pregnant normotensive women as the control group and 50 pregnant women diagnosed with preeclampsia oreclampsia as the case group. The Ethical clearance of this study was obtained from the Institutional Review Board of Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. Results: Out of 100 patients, the control group consisted of 30% individuals aged 21-25 years, while the case group had 32% individuals aged 16-20 years. The mean age for the control group was 23.11 years (SD 5.9), and for the case group, it was 24.5 years (SD 6.3). The distribution of study patients based on risk factors reveals statistically significant differences between the control and case groups for the variable’s \"gravidity\" and \"antenatal care\" (p < 0.05). The case group had a higher proportion of primigravida (first-time pregnancy) and irregular or no antenatal care. However, no significant differences were observed for the variables \"family history of hypertension\" and \"gestational age\" (p > 0.05). In terms of clinical parameters, the case group exhibited significantly higher prevalence of proteinuria at all levels (1+, 2+, and 3+) compared to the control group. The blood pressure readings, both systolic and diastolic, were also significantly higher in the case group. Moreover, the case group had significantly lower serum calcium levels than the control group. These differences were statistically significant with p-values indicating p<0.01 o p< 0.001. Basis on the results the significant risks factors associated with Preeclampsia were observed, Gravidity (p=0.05), Antenatal care (p=0.05), Proteinuria (p=0.001), Blood Pressure-Systolic(mmHg)(p=0.001), Blood Pressuredystonic (mmHg) (p=0.001), Serum Calcium Level (mg/dl) (p=0.001). Conclusion: The study observed Gravidity, Antenatal care Proteinuria, Blood Pressure - Systolic (mmHg), Blood Pressure - dystonic (mmHg), Serum Calcium Level (mg/dl) were the significant factors associated with the Preeclamptic Women in Bangladesh.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129743992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Causes of Post-Menopausal Bleeding: A Hospital-Based Study","authors":"S. Naher, Ferdous Ara Shuchi, Sufia Begum Shompi, Samira Areen","doi":"10.36348/sijog.2023.v06i08.001","DOIUrl":"https://doi.org/10.36348/sijog.2023.v06i08.001","url":null,"abstract":"Midline cerebral congenital malformations, despite their relative rarity in the general population, with their high rate of Introduction: Postmenopausal bleeding is frequent in gynecology and occurs approximately in 5% to 10% of postmenopausal women. But most of the causes of post-menopausal bleeding are benign and treated conservatively. Women with postmenopausal bleeding have a primary or secondary malignancy of about 10%. So before starting treatment malignancy must be excluded. Common malignancies among them are endometrial or cervical carcinoma and rarely, ovarian cancer. The incidence of malignancy in the postmenopausal period remains sufficiently high, so it requires immediate investigations for early diagnosis, prompt treatment, and vigilant follow-up. The objective of the study is to evaluate the causes of postmenopausal bleeding in tertiary care hospitals in Dhaka city. Methods: This retrospective study was conducted at the Department of Obstetrics and Gynecology in Delta Medical College and Hospital, Dhaka, Bangladesh. The study duration spanned 12 months from July 2022 to June 2023. The study population consisted of 72 patients who presented with postmenopausal bleeding. The sampling for this study was conducted using a consecutive sampling method. Ethical approval was obtained from the ethical review committee of the study hospital. Descriptive statistics were used to summarize the demographic and clinical characteristics of the study participants. For the statistical analysis, the Statistical Package for the Social Sciences (SPSS). Results: Among 72 cases of postmenopausal bleeding, we found 9 cases of cancer (12.50%). Among them, 2 cases were cancer of the uterine cervix and 7 cases were cancer of the uterine corpus. Benign pathology was more frequent (63 cases: 87.50%), essentially presented atrophic endometritis 15 cases(20.83%), endometrial hyperplasia without atypia27.78% cases, endometrial polyp 16.67% cases, endocervical polyp 5.56% cases, cervical polyp 8.33%, leiomyoma found in 5.53% cases and preinvasive disease about 2.78% cases. Histopathological findings in 2 cases of carcinoma cervix were invasive squamous cell carcinoma and 7cases of endometrial cancer were endometrial adenocarcinoma. Cancer increased with advanced age while the incidence of bleeding decreased with age. Within 45 to 65 years of age is more frequent to develop post-menopausal bleeding. Conclusion: Even though causes of post-menopausal bleeding are mostly benign and treated conservatively but malignancy must be ruled out by endometrial and cervical biopsy.","PeriodicalId":394508,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121491098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}