一家三级医院对高危和重危妊娠围产期结果的研究

Afroza Sultana, Rina Haider, Kulsum Akhter, Shamsad Begum
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引用次数: 0

摘要

导言:高危妊娠和重度高危妊娠的特点是母亲和胎儿发生并发症的风险增加,这些并发症可能由多种因素造成,如母亲年龄、医疗状况、生活习惯和以前的妊娠经历。这些并发症是一个重大问题,主要发生在孟加拉国等发展中国家,因为这些国家的孕产妇和婴儿死亡率居高不下。与高危和重危妊娠相关的孕产妇并发症可能包括孕产妇死亡、大出血、败血症和高血压疾病,而胎儿并发症可能包括早产、胎儿生长受限和死胎。本研究旨在调查高危和重危妊娠的围产期结局。研究方法这项前瞻性目的性研究针对达卡班加班杜谢赫-穆吉布医科大学(BSMMU)妇产科在 2007 年 7 月至 2007 年 12 月期间收治的病人。共有数百名高危孕妇(N=100)参与了研究,其中 85 人(n=85)的评分为 3-6 分,被列为高危孕妇;15 人(n=15)的评分为 7 分或以上,被列为重危孕妇。每个研究对象的所有相关数据都记录在事先设计好的数据收集表上。所有收集到的数据均通过电脑统计软件(Instat)进行整理和分析。对研究变量的流行率进行了卡方检验(P<0.05为显著性水平,95%CI)。本研究获得了孟加拉国达卡 BSMMU 机构审查委员会(IRB)的伦理许可。研究结果在高危组(n=85)中,约四分之一的患者(22.25.9%)和重危组(n=15)中,一名患者(1.6.7%)经阴道分娩,高危孕妇中有 63 名患者(63.74.1%)进行了剖腹产,重危孕妇中有 14 名患者(14.93.3%)进行了剖腹产。风险组别和分娩方式的分布具有高度统计学意义(P <0.001)。在 63 例患者(n1=63)中,19 例(19,30.2%)因胎儿窘迫需要剖腹产,15 例(15,30.16%)为胎位不正。在 41 名患者(n2=14)中,最常见的指征是 8 名患者(8,57.1%)曾有剖腹产史,且存在多种风险因素。在高危组(n=65)和重危组(n2=14)中,有 9 名新生儿(9,13.6%)出现了出生窒息,有 5 名新生儿(5,35.7%)出现了出生窒息。根据结果,高危妊娠组(n=85)有 4 名新生儿死亡(4,4.5%),重危妊娠组(n=15)有 1 名新生儿死亡(1,6.3%)。结论研究发现了与高危和重危妊娠相关的各种产科并发症和结果。结果表明,与高危妊娠相比,重危妊娠的剖腹产比例明显更高。此外,总体结果良好,在 100 个孕产妇风险组别中,仅有 5 例新生儿死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perinatal Outcome in High-Risk & Severe-Risk Pregnancy- A Study in a Tertiary Care Hospital
Introduction: High-risk & severe-risk pregnancies are characterized by increased risks of complications for both the mother and the fetus, which can result from several factors such as maternal age, medical situations, lifestyle habits, and previous pregnancies. These complications are a major concern, mostly in developing countries like Bangladesh, where maternal and infant mortality rates remain high. Maternal complications associated with high-risk and severe-risk pregnancies may include maternal death, severe bleeding, sepsis, and hypertensive disorders, while fetal complications may include preterm delivery, fetal growth restriction, and stillbirth. The objective of this study was to investigate the perinatal outcomes of high-risk and severe-risk pregnancies. Methods: This prospective purposive study was carried out on the admitted patients in the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from July 2007 to December 2007. Total hundreds of risk groups pregnant women (N=100) were enrolled in the study among them eighty-five (n=85) scoring 3-6 included as high risk pregnancy and fifteen (n=15) scoring 7 or more included as severe-risk pregnancy. All relevant data were recorded for each individual study subject on predesigned data collection sheet. All collected data were compiled and analyzed by computer-based statistical software (Instat). Chi-square tests were performed to compare the prevalence of study variables where, p < 0.05 considered the level of significance with 95%CI. Ethical clearance of this study was obtained from the Institutional Review Board (IRB) of BSMMU, Dhaka, Bangladesh. Results: In the high-risk group (n=85), around one-fourth of the patients (22,25.9%) and in a severe- risk group (n=15), one patient (1,6.7%) underwent vaginal delivery, Caesarean section was done in sixty-three patients (63,74.1%) in high-risk pregnant women and fourteen patients (14,93.3%) in severe-risk pregnant women respectively. The distribution of risk group and mode of delivery is statistically highly significant (P <0.001). Out of sixty-three patients (n1=63), nineteen (19, 30.2%) were required to be delivered by caesarean section for fetal distress and fifteen (15, 30.16%) were malpresentation. Out of forty-one patients (n2=14), the most common indications were a history of previous caesarean section with multiple risk factors in eight patients (8, 57.1%). Birth asphyxia was present in nine neonates (9, 13.6%) in a high-risk group (n = 65) and a severe- risk group (n2=14), and birth asphyxia was present in five neonates (5, 35.7%). Based on the outcome, in high-risk pregnancy (n=85), four neonates (4, 4.5%) died and in severe-risk pregnancy (n=15), one (1, 6.3%) died. Conclusion: The study found various obstetric complications and outcomes associated with high-risk and severe-risk pregnancies. The results indicated a significantly higher proportion of caesarean sections performed in severe-risk pregnancies compared to high-risk pregnancies. Moreover, the overall outcome was favorable, with only five neonatal deaths reported among the one hundred maternal risk groups.
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