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Prevalence of antihypertensive medication adherence and associated factors in India: A systematic review and meta-analysis.
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-12-21 DOI: 10.1016/j.hipert.2024.11.005
B Pal, A Dutta, V Chaudhary, S Kumari, S Meenakshi, K Murti
{"title":"Prevalence of antihypertensive medication adherence and associated factors in India: A systematic review and meta-analysis.","authors":"B Pal, A Dutta, V Chaudhary, S Kumari, S Meenakshi, K Murti","doi":"10.1016/j.hipert.2024.11.005","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.11.005","url":null,"abstract":"<p><strong>Background: </strong>Non-adherence to antihypertensive medication is a key factor contributing to uncontrolled blood pressure and the subsequent complications of hypertension. Despite its importance, there is a lack of data regarding the prevalence of and factors associated with non-adherence to medication among individuals with hypertension in India. This review aimed to assess medication adherence rates among hypertensive patients in India and identify the factors influencing non-adherence.</p><p><strong>Methods: </strong>A comprehensive search was conducted across PubMed, Scopus, Embase, and Google Scholar. Studies reporting medication adherence/non-adherence to antihypertensive medications in India, using the Morisky Medication Adherence Scale (MMAS), with publication dates up to July 2023, were included.</p><p><strong>Results: </strong>Twelve studies were included, involving a total of 3164 participants. The pooled rate of medication adherence to antihypertensive medications in India was determined to be 15.8% (95% CI: 4.4; 43.4). The important factors associated with non-adherence included higher age, medication regimen complexity, low socioeconomic status, low education levels, uncontrolled blood pressure, and comorbidities.</p><p><strong>Conclusions: </strong>The adherence rate to antihypertensive medication was observed to be quite low. Therefore, it is imperative to enhance the rate of medication adherence among individuals with hypertension in order to attain effective blood pressure control and reduce the burden of non-communicable diseases.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the effectiveness of aliskiren and ramipril for the management of hypertension: A systematic review and meta-analysis.
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-12-10 DOI: 10.1016/j.hipert.2024.11.002
T Alam, M Asif Ansari
{"title":"Comparison of the effectiveness of aliskiren and ramipril for the management of hypertension: A systematic review and meta-analysis.","authors":"T Alam, M Asif Ansari","doi":"10.1016/j.hipert.2024.11.002","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.11.002","url":null,"abstract":"<p><strong>Objective: </strong>Ramipril is an important option in the management of hypertension, while the role of aliskiren is still up for debate. We aim to meta-analyse and compare the effect of aliskiren with ramipril by measuring mean difference in systolic blood pressure (mdSBP) and mean difference in diastolic blood pressure (mdDBP).</p><p><strong>Methods: </strong>The search was conducted using the PubMed and Cochrane databases for eligible randomized clinical trials (RCTs) to perform a meta-analysis from January 2000 to May 2024. RCTs that included hypertensive patients who were under either aliskiren or ramipril treatment were included in the analysis. The risk of bias was evaluated using RoB 2.0. This study is registered with PROSPERO: CRD42024577105.</p><p><strong>Results: </strong>Four studies were included: two studies were carried out for 2 months, and two were carried out for 6 months, including 693 and 329 patients, respectively, with mild to moderate hypertension and a mean age of 55.2 years. After 2 months, mdDBP was found to be significant (mdDBP=0.85mmHg, 95% CI: 0.73-0.97, I<sup>2</sup>=0%), but mdSBP was found to be non-significant (mdSBP=0.0mmHg, 95% CI: -0.17-0.17, I<sup>2</sup>=0%). There was a significant difference in the mdSBP (mdSBP=3.15mmHg, 95% CI: 2.13-4.17, I<sup>2</sup>=84%) and mdDBP (mdDBP=1.2mmHg, 95% CI: 1.09-1.31, I<sup>2</sup>=0%) at 6 months.</p><p><strong>Conclusion: </strong>Aliskiren provides, in the short term, a slight improvement in BP in non-elderly hypertensive patients without diabetes or previous cardio-cerebrovascular disease.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physicians' perception of guideline recommendations for the treatment of resistant hypertension by renal denervation: Resistant Hypertension Working Group, Argentine Hypertension Society.
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-12-06 DOI: 10.1016/j.hipert.2024.10.003
N F Renna, L Brandani, R Parodi, C Kottliar, E Ylarri, G Lavenia, M Marin, M Ruise, R Sanchez, D Cianfagna, G Botvinik, P Rumi, V Ferreti, P Rodirguez
{"title":"Physicians' perception of guideline recommendations for the treatment of resistant hypertension by renal denervation: Resistant Hypertension Working Group, Argentine Hypertension Society.","authors":"N F Renna, L Brandani, R Parodi, C Kottliar, E Ylarri, G Lavenia, M Marin, M Ruise, R Sanchez, D Cianfagna, G Botvinik, P Rumi, V Ferreti, P Rodirguez","doi":"10.1016/j.hipert.2024.10.003","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.10.003","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates the perceptions and knowledge of specialized Argentine physicians regarding renal denervation (RDN) as a treatment for resistant hypertension (R-HT).</p><p><strong>Method: </strong>A survey was conducted among 206 physicians, mainly cardiologists and internists, to assess their awareness and perceptions of RDN. Data were analyzed using descriptive statistics and Spearman's Rho correlation.</p><p><strong>Results: </strong>The survey revealed that 83% of the responders are aware of RDN. Despite this high awareness, only 60% believe in its safety, while 33.2% are uncertain, and 6.8% consider it unsafe. Significant correlations were found between the awareness of RDN and perceptions of its efficacy and safety.</p><p><strong>Conclusions: </strong>The study highlights a gap between knowledge and confidence in RDN among specialized Argentine physicians. Continuous education and shared decision-making are crucial to improve the adoption of RDN in clinical practice. Long-term safety and efficacy data support RDN as a valuable tool for managing R-HT. Addressing safety concerns through targeted educational initiatives is essential.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Real-world efficacy and safety of baroreceptor activation therapy in a series of patients with refractory arterial hypertension].
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-12-05 DOI: 10.1016/j.hipert.2024.10.004
A Bustos-Merlo, D Rico-López, F Jaén-Águila, C López-Espada, M I Rodríguez-Macías, J D Mediavilla-García
{"title":"[Real-world efficacy and safety of baroreceptor activation therapy in a series of patients with refractory arterial hypertension].","authors":"A Bustos-Merlo, D Rico-López, F Jaén-Águila, C López-Espada, M I Rodríguez-Macías, J D Mediavilla-García","doi":"10.1016/j.hipert.2024.10.004","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.10.004","url":null,"abstract":"<p><p>The number of patients suffering from refractory hypertension and advanced-stage chronic heart failure (CHF) is progressively increasing. In recent years, device-mediated therapies have been developed as an alternative or adjunct to conventional medical treatment. Our primary objective is to describe the clinical experience in a series of patients with refractory hypertension following the implantation of baroreceptor activation therapy (BAT). We analyzed 5 patients with refractory hypertension, one of whom also had CHF, treated in a specialized cardiovascular risk clinic. After the implantation of the Barostim device with an average activation of 3.64mA (ranging from 2.80 to 5.4), there was a mean reduction of 30±7.68mmHg (P=0.001) and 13.40±9.07mmHg (P=0.03) in systolic and diastolic blood pressure, respectively, as measured by ambulatory blood pressure monitoring (ABPM), along with a heart rate reduction of 25±9.13 bpm (P=0.004). A reduction in the number of antihypertensive medications required for blood pressure control was observed, with an average of 5.2 medications, as well as an improvement in functional class. No adverse events were recorded in our patient series. Currently, BAT is considered a compassionate-use alternative for blood pressure control in patients with refractory hypertension and failure of pharmacological treatment and other invasive techniques, such as renal denervation.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of different domains of sedentary behavior and cardiovascular risk factors in adolescents: Cross-sectional study. 青少年不同领域的久坐行为与心血管风险因素的关系:横断面研究
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-11-25 DOI: 10.1016/j.hipert.2024.10.002
E P Antunes, W R Tebar, G G Cucato, C C M Silva, I Leoci, A B Dos Santos, G Ferrari, D G D Christofaro
{"title":"Association of different domains of sedentary behavior and cardiovascular risk factors in adolescents: Cross-sectional study.","authors":"E P Antunes, W R Tebar, G G Cucato, C C M Silva, I Leoci, A B Dos Santos, G Ferrari, D G D Christofaro","doi":"10.1016/j.hipert.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.10.002","url":null,"abstract":"<p><strong>Background: </strong>Sedentary behavior (SB) has been related to cardiovascular risk factors (CVRF) such as high BMI, waist circumference (WC) and blood pressure (BP), including pediatric populations. However, it is still unclear whether the association between SB and CVRF could be domain dependent. Therefore, this study aimed to analyze the relationship between sedentary at different domains (time spent in TV, videogames, computer, smartphone) with CVRF in adolescents.</p><p><strong>Methods: </strong>A sample of 1011 adolescents (10-17 years old; 55.1% girls) was assessed. The different BS domains were obtained through a questionnaire, as well as socioeconomic status, habitual physical activity, smoking and alcohol consumption. BMI was calculated by objectively measured height and body mass, WC was assessed at middle point between the last rib and iliac crest, and BP was assessed by a digital oscillometric device. The relationship between SB and CVRF was determined by quantile regression, adjusted for sex, age, socioeconomic status, physical activity, smoking and alcohol consumption.</p><p><strong>Results: </strong>Elevated time in smartphone use was associated with higher median values of WC (β=1.88; 95%CI: (0.27; 3.49) and SBP (β=2.70; 95%CI: 0.35; 5.05). High total time spent in SB was associated with higher median values of BMI (β=0.68; 95%CI=(0.02; 1.35), WC (β=1.95; 95%=0.47; 3.42) and SBP (β=2.52; 95%CI: 0.37; 4.68).</p><p><strong>Conclusions: </strong>Smartphone use and total SB time were related to higher CVRF in adolescents. Cardiovascular health promotion strategies should focus on reducing SB in pediatric populations, especially smartphone use.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Position paper on the 2024 ESH clinical practice guidelines for the management of arterial hypertension in Spain. 关于 2024 年西班牙动脉高血压管理 ESH 临床实践指南的立场文件。
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-11-19 DOI: 10.1016/j.hipert.2024.09.003
E Rodilla, M Benítez Camps, L Castilla Guerra, M I Egocheaga Cabello, J Gamarra Ortiz, M Á María Tablado, N Muñoz Rivas, V Pallarés-Carratalá, J Polo García, J A García Donaire
{"title":"Position paper on the 2024 ESH clinical practice guidelines for the management of arterial hypertension in Spain.","authors":"E Rodilla, M Benítez Camps, L Castilla Guerra, M I Egocheaga Cabello, J Gamarra Ortiz, M Á María Tablado, N Muñoz Rivas, V Pallarés-Carratalá, J Polo García, J A García Donaire","doi":"10.1016/j.hipert.2024.09.003","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.09.003","url":null,"abstract":"<p><p>The 2024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension (ESH Guidelines 2024) have recently been published, a brief document but with a very elaborate infographic that summarizes as much as possible the previous guidelines for the management of arterial hypertension (HTN), aimed at serving as a quick reference tool to make decisions in daily clinical practice. The main objective of this work is to analyze the recommendations and innovations of these guidelines from the perspective of their applicability and taking into account all the scientific societies in the specialty of Family and Community Medicine, Internal Medicine and the Spanish Society of Hypertension (SEHLELHA) in order to achieve more homogeneous and evidence-based care for HTN in Spain. The most important results include the maintenance of the thresholds to define HTN and the therapeutic objectives, as well as the recommendation to initiate pharmacological treatment based on both the blood pressure values and the cardiovascular risk estimated by SCORE2 and the presence of organic damage. New are the introduction of practical tables to estimate the fragility of hypertensive subjects based on their age and autonomy, as well as precise recommendations for monitoring HTN. In summary, the ESH 2024 Guidelines represent a useful, reasoned and concise instrument that can serve as a tool to improve the control of HTN in our environment.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, trends, and associated factors of isolated systolic, diastolic, and systolic-diastolic hypertension in Peru: A nine-year analysis of the Demographic and Family Health Survey. 秘鲁孤立性收缩期、舒张期和收缩期-舒张期高血压的患病率、趋势和相关因素:人口与家庭健康调查九年分析》。
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-11-16 DOI: 10.1016/j.hipert.2024.10.001
V J Vera-Ponce, F E Zuzunaga-Montoya, L E M Vásquez-Romero, J A Loayza-Castro, C I Gutierrez De Carrillo, E Vigil-Ventura
{"title":"Prevalence, trends, and associated factors of isolated systolic, diastolic, and systolic-diastolic hypertension in Peru: A nine-year analysis of the Demographic and Family Health Survey.","authors":"V J Vera-Ponce, F E Zuzunaga-Montoya, L E M Vásquez-Romero, J A Loayza-Castro, C I Gutierrez De Carrillo, E Vigil-Ventura","doi":"10.1016/j.hipert.2024.10.001","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.10.001","url":null,"abstract":"<p><strong>Introduction: </strong>While HTN is widely seen as a primary threat to cardiovascular conditions worldwide, it is essential to recognize that not all HTN is identical.</p><p><strong>Objective: </strong>To determine the prevalence, trend, and factors associated with each type of HTN: isolated systolic (ISH), isolated diastolic (IDH), and systolic-diastolic (SDH).</p><p><strong>Methods: </strong>A secondary analysis of data from the Demographic and Family Health Survey from 2014 to 2022 was conducted. For the analysis of associated factors, a Poisson regression model with robust variance was implemented to calculate adjusted prevalence ratios (aPR) along with their 95% confidence intervals.</p><p><strong>Results: </strong>The prevalence was 7.02%, 1.55%, and 3.28% for ISH, IDH, and SDH, respectively. ISH showed a decline in 2022, unlike the other two types, which seem to be on the rise. A statistically significant association was found in men and an increased risk with age for ISH and SDH, unlike IDH, where age acts as a protective factor. Additional factors identified include smoking and excessive alcohol consumption, while a high intake of fruits/vegetables offers a protective effect. Obesity and diabetes were associated with a higher risk, and significant variations by region and altitude, as well as among ethnic groups, were observed.</p><p><strong>Conclusions: </strong>Significant differences in the prevalence of HTN subtypes have been found, underscoring the heterogeneity of this chronic condition, both in related factors and in trends over the years.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Peculiarities in the management of arterial hypertension in the elderly: Consensus document of the Central American and Caribbean Society of arterial hypertension]. [老年人动脉高血压管理的特殊性:中美洲和加勒比动脉高血压学会共识文件]。
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-11-04 DOI: 10.1016/j.hipert.2024.09.004
C Sepulveda Gallardo, A I Barrientos, M H Koretzky, F Wyss, O Valdez Tiburcio, N Báez Noyer, E Sanchez, A Gonzalez, W Dones, P López Contreras, M Camafort
{"title":"[Peculiarities in the management of arterial hypertension in the elderly: Consensus document of the Central American and Caribbean Society of arterial hypertension].","authors":"C Sepulveda Gallardo, A I Barrientos, M H Koretzky, F Wyss, O Valdez Tiburcio, N Báez Noyer, E Sanchez, A Gonzalez, W Dones, P López Contreras, M Camafort","doi":"10.1016/j.hipert.2024.09.004","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.09.004","url":null,"abstract":"<p><p>Arterial hypertension is one of the most prevalent diseases in the field of geriatrics and is also a risk factor for pathologies that frequently result in hospital admissions, such as heart failure and stroke. This article addresses both pharmacological and non-pharmacological diagnosis and treatment strategies, focusing on the role of frailty as a guiding principle in determining the most appropriate course of treatment, emphasizing patient-centred prescribing. Furthermore, the article reviews other frequent topics, such as polypharmacy and orthostatic hypotension. Moreover, a concise overview of the current evidence in geriatrics on ambulatory blood pressure monitoring and self-measurement of blood pressure will be provided. Furthermore, a brief summary of the underlying pathophysiology and current epidemiological trends is provided. This consensus is founded upon the initial premise that a comprehensive geriatric assessment should be conducted to ascertain whether a blood pressure reduction strategy could confer a net benefit for elderly patients while simultaneously avoiding an increase in the safety risks associated with these strategies and preventing a de-prescription due to ageism. This is particularly important given the significance of maintaining optimal blood pressure control to prevent related complications.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on the diagnosis of the pheochromocytoma. 嗜铬细胞瘤诊断的最新进展。
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-10-10 DOI: 10.1016/j.hipert.2024.08.001
E Achote, O F Arroyo Ripoll, M Araujo-Castro
{"title":"Update on the diagnosis of the pheochromocytoma.","authors":"E Achote, O F Arroyo Ripoll, M Araujo-Castro","doi":"10.1016/j.hipert.2024.08.001","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.08.001","url":null,"abstract":"<p><p>Pheochromocytoma is a rare neuroendocrine tumour that develops from chromaffin cells in the adrenal medulla and is characterised by the excessive production of catecholamines and their metabolites. Diagnostic confirmation is performed by detecting elevated levels of catecholamines and/or their metabolites in plasma or 24-h urine. In the case of moderate elevations of normetanephrine, the clonidine suppression test may be useful to differentiate between endogenous hypersecretion and false positive results. Once the biochemical diagnosis is performed, the tumour localisation is carried out using imaging techniques and sometimes with nuclear medicine imaging tests. Furthermore, in all patients with pheochromocytomas it is recommended to perform a genetic study to identify hereditary disorders that may be present in more than 30% of cases and to perform a cardiological evaluation to rule out the presence of cardiovascular involvement secondary to the catecholamine hypersecretion.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Arterial stiffness detection in women with recent history of pre-eclampsia]. [近期有先兆子痫病史的妇女的动脉僵化检测]。
IF 1.2
Hipertension y Riesgo Vascular Pub Date : 2024-10-09 DOI: 10.1016/j.hipert.2024.07.007
A M Ghelfi, M N Lassus, F A Passarino, R F Mamprin D'Andrea, L N Fierro, L L Velez, E A Hails, M A Paciocco, J G Kilstein, J O Galíndez
{"title":"[Arterial stiffness detection in women with recent history of pre-eclampsia].","authors":"A M Ghelfi, M N Lassus, F A Passarino, R F Mamprin D'Andrea, L N Fierro, L L Velez, E A Hails, M A Paciocco, J G Kilstein, J O Galíndez","doi":"10.1016/j.hipert.2024.07.007","DOIUrl":"https://doi.org/10.1016/j.hipert.2024.07.007","url":null,"abstract":"<p><strong>Introduction: </strong>Preeclampsia (PE) is a complication of hypertensive disorders of pregnancy, whose pathophysiology involves endothelial dysfunction. Early establishment of subclinical vascular lesions such as arterial stiffness (AS) could explain the development of cardiovascular disease later in life. AS can be assessed non-invasively using carotid-femoral pulse wave velocity (cf-PWV), aortic systolic blood pressure (ao-SBP) and augmentation index (IAx). We aim to determine cf-PWV, ao-SBP and AIx in women who recently underwent PE and compare it with a control group.</p><p><strong>Materials and methods: </strong>Cross-sectional study, carried out from 2022 to 2023 in Argentina. Group 1: women who developed PE.</p><p><strong>Exclusion criteria: </strong>history of chronic hypertension, diabetes, autoimmune disease, chronic kidney disease, cardiovascular disease, PE in previous pregnancies; treatment with calcium antagonists during pregnancy; treatment with calcium antagonists, angiotensin-converting enzyme inhibitors or diuretics in the postpartum period. Group 2: healthy postpartum periods. PWV-cf, ao-SBP and IAx were measured in the first 72hours postpartum using Aortic.</p><p><strong>Results: </strong>Seventy-onewomen were included: Group 1 (n=30); Group 2 (n=41). Group 1 presented higher PWV-cf=6.70±0.68 vs. 5.41±0.48 m/s (P<.0001); ao-SBP=118.3±9.6 vs. 101.2±9.8mmHg (P<.0001); and IAu=22.7±10.7 vs. 9.3±11.9% (P<.0001). In Group 1 there were 25 of 30 women who presented AS parameters (OR=8.50; 95% CI=3.32-15.29; P<.0001).</p><p><strong>Conclusion: </strong>Patients with a recent history of PE showed higher cf-PWV, ao-SBP and AIx values, compatible with AS.</p>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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