Hipertension y Riesgo Vascular最新文献

{"title":"Management of high blood pressure in acute stroke. What is the right answer?","authors":"P. Armario , S.M. Garcia-Sánchez , P. Cardona","doi":"10.1016/j.hipert.2022.07.003","DOIUrl":"10.1016/j.hipert.2022.07.003","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40614754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial forms and molecular profile of primary hyperaldosteronism","authors":"M. Araujo-Castro ,&nbsp;P. Martín Rojas-Marcos ,&nbsp;P. Parra Ramírez","doi":"10.1016/j.hipert.2022.05.007","DOIUrl":"10.1016/j.hipert.2022.05.007","url":null,"abstract":"<div><p>Primary hyperaldosteronism (PAH) is the most frequent cause of secondary arterial hypertension. Most PAHs occur sporadically, but 5% of cases have a hereditary origin (familial PAH). Four forms of familial PAH have been described. Type I familial PAH is produced by a fusion of the CYP11B2<span><span> and CYP11B1 genes, in this way the synthesis of aldosterone becomes to be regulated by ACTH instead of by angiotensin II. In type II, III and IV familial PAH there is an increase in the transcription and expression of CYP11B2 responsible for aldosterone synthesis due to a germinal mutation in CLCN2<span>, KCNJ5 and </span></span>CACNA1H, respectively. On the other hand, somatic mutations have been identified in 50% of sporadic PAHs, with gain-of-function mutations at the level of KCNJ5, ATP1A1, ATP2B3 and CACNA1D being the most common. This review provides a detailed description of the different forms of familial PAH and the molecular profile of patients with sporadic PAH.</span></p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40464382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hipertensión nocturna aislada en individuos con el virus de la inmunodeficiencia humana","authors":"W. Espeche ,&nbsp;M.R. Salazar ,&nbsp;J. Minetto ,&nbsp;C. Suarez-Fernandez ,&nbsp;I. De los Santos Gil ,&nbsp;A. Gomez Berrocal","doi":"10.1016/j.hipert.2022.07.002","DOIUrl":"10.1016/j.hipert.2022.07.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Isolated nocturnal hypertension is associated with a greater number of cardiovascular events and target organ damage due to arterial hypertension. It has been observed that patients in the general population with this entity do not have high blood pressure figures in the office; and it is necessary to perform an outpatient measurement to unmask it. The prevalence in special populations is not fully described. The objective of the following study is to describe the prevalence of isolated nocturnal hypertension in a population living with the human immunodeficiency virus and to observe its relationship with the categories of office blood pressure and the phenotypes of the 24-hour ambulatory blood pressure measurement.</p></div><div><h3>Methodology</h3><p>A retrospective cohort was carried out in a population with human immunodeficiency virus in a public hospital in Spain, clinical epidemiological characteristics, office blood pressure measurements and 24-hour ambulatory blood pressure measurement (ABPM) were recorded. An analysis was performed based on the different ABPM blood pressure phenotypes, as well as based on the different office blood pressure categories, the risks for isolated nocturnal hypertension were calculated.</p></div><div><h3>Results</h3><p>One hundred and sixteen individuals, without antihypertensive medication or history of established cardiovascular disease, were included in the analysis. A prevalence of nocturnal hypertension of 23.3% was described. It was not possible to demonstrate significant differences between phenotypes by ABPM of any variable specific to HIV.</p><p>There were no adjusted risk differences between the different categories of office normotensives.</p></div><div><h3>Conclusions</h3><p>Isolated nocturnal hypertension is more frequent in patients with HIV and office blood pressure values in normotensive patients are not sufficient to predict isolated nocturnal hypertension.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40588873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No todo dolor lumbar es un cólico nefrítico","authors":"K. Griñan Ferre ,&nbsp;J. Torras Borrell ,&nbsp;M.C. Ríos Jiménez","doi":"10.1016/j.hipert.2022.05.006","DOIUrl":"10.1016/j.hipert.2022.05.006","url":null,"abstract":"<div><p>Low back pain is one of the most frequent reasons for consultation in primary care. Sometimes it is not easy to make a good differential diagnosis, because the number of pathologies that can express themselves with such symptoms is very wide and a complementary test or referral to the reference hospital is not always indicated. The following is a clinical case of a 59-year-old female patient with a history of dyslipidemia treated with ezetimibe, who consulted again for breakthrough low back pain, which was finally diagnosed as a penetrating ulcer of the abdominal aorta, treated endovascularly by the vascular surgery service. The clinical case aims to provide an overview of the acute treatment of aortic syndrome, showing the differences compared to the management of other common pathologies in primary care with the same clinical expression.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54306056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing high blood pressure in hypertensive patients with an acute ischemic stroke","authors":"I. Mursalov ,&nbsp;A. Muneer ,&nbsp;R. Aringazina","doi":"10.1016/j.hipert.2022.04.001","DOIUrl":"10.1016/j.hipert.2022.04.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Arterial hypertension (AH) is one of the key risk factors and triggers for the development of acute cerebrovascular accident. The purpose of the study is to investigate the peculiarities and rates of blood pressure reduction in AH patients during the acute period of ischemic stroke depending on the patients’ sex, age, medical history, and clinical characteristics.</p></div><div><h3>Material and methods</h3><p>The study involved 120 patients aged 41–77 years, of whom there were 47 (39.2%) men and 73 (60.8%) women. All enrolled patients had established diagnoses of AH and acute ischemic cerebrovascular accident (acute ischemic stroke, AIS), with the latter diagnosed within the first 24<!--> <!-->h from onset. The follow-up period was 14 days.</p></div><div><h3>Results</h3><p>An increase in diastolic blood pressure was associated with higher scores on the National Institutes of Health Stroke Scale (NIHSS, <em>r</em> <!-->=<!--> <!-->0.301, <em>p</em> <!-->=<!--> <!-->0.026) and Rankin scale (<em>r</em> <!-->=<!--> <!-->0.225, <em>p</em> <!-->=<!--> <!-->0.030), as well as a worse health status at the time of discharge from hospital (<em>r</em> <!-->=<!--> <!-->0.318, <em>p</em> <!-->=<!--> <!-->0.021).</p></div><div><h3>Conclusion</h3><p>Diastolic blood pressure can be considered a marker of the severity of neurological disorders in AIS, which should be considered when monitoring such patients.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76960967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guía práctica sobre el diagnóstico y tratamiento de la hipertensión arterial en España, 2022. Sociedad Española de Hipertensión - Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA)","authors":"M. Gorostidi ,&nbsp;T. Gijón-Conde ,&nbsp;A. de la Sierra ,&nbsp;E. Rodilla ,&nbsp;E. Rubio ,&nbsp;E. Vinyoles ,&nbsp;A. Oliveras ,&nbsp;R. Santamaría ,&nbsp;J. Segura ,&nbsp;A. Molinero ,&nbsp;D. Pérez-Manchón ,&nbsp;M. Abad ,&nbsp;J. Abellán ,&nbsp;P. Armario ,&nbsp;J.R. Banegas ,&nbsp;M. Camafort ,&nbsp;C. Catalina ,&nbsp;A. Coca ,&nbsp;J.A. Divisón ,&nbsp;M. Domenech ,&nbsp;J.A. García-Donaire","doi":"10.1016/j.hipert.2022.09.002","DOIUrl":"10.1016/j.hipert.2022.09.002","url":null,"abstract":"<div><p>Hypertension is the most important risk factor for global disease burden. Detection and management of hypertension are considered as key issues for individual and public health, as adequate control of blood pressure levels markedly reduces morbidity and mortality associated with hypertension. Aims of these practice guidelines for the management of arterial hypertension of the Spanish Society of Hypertension include offering simplified schemes for diagnosis and treatment for daily practice, and strategies for public health promotion. The Spanish Society of Hypertension assumes the 2018 European guidelines for management of arterial hypertension developed by the European Society of Cardiology and the European Society of Hypertension, although relevant aspects of the 2017 American College of Cardiology/American Heart Association guidelines and the 2020 International Society of Hypertension guidelines are also commented. Hypertension is defined as a persistent elevation in office systolic blood pressure ≥ 140 and/or diastolic blood pressure ≥ 90 mmHg, and assessment of out-of-office blood pressure and global cardiovascular risk are considered of key importance for evaluation and management of hypertensive patients. The target for treated blood pressure should be &lt; 130/80 for most patients. The treatment of hypertension involves lifestyle interventions and drug therapy. Most people with hypertension need more than one antihypertensive drug for adequate control, so initial therapy with two drugs, and single pill combinations are recommended for a wide majority of hypertensive patients.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33479647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importancia del conocimiento óptimo de los profesionales sanitarios en el diagnóstico inicial de la hipertensión arterial","authors":"A. Dalfó Pibernat ,&nbsp;A. Ovejas López ,&nbsp;E. Pallarés Sanz ,&nbsp;A. Dalfó Baqué","doi":"10.1016/j.hipert.2022.03.003","DOIUrl":"10.1016/j.hipert.2022.03.003","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54305935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olmesartán y enteropatía una década después: una asociación quizá no tan excepcional","authors":"C. Albaladejo Blanco,&nbsp;L. Martínez Capilla,&nbsp;J.A. Martín García","doi":"10.1016/j.hipert.2021.12.002","DOIUrl":"10.1016/j.hipert.2021.12.002","url":null,"abstract":"<div><p>Olmesartan is a potent angiotensin II receptor antagonist commonly used in the treatment of high blood pressure.</p><p>During the last decade, several cases of sprue-like enteropathy have been described associated with the use of this drug - with severe clinical involvement that requires hospitalization - but fortunately with complete remission after its discontinuation.</p><p>We present the case of a multi-pathological 82-year-old woman with a chronic diarrhoeal syndrome that resulted in a weight loss of 20<!--> <!-->kg over the last three months. She was prescribed dual therapy for her hypertension: olmesartan 40<!--> <!-->mg, torasemide 10<!--> <!-->mg, and lercanidipine 10<!--> <!-->mg/day.</p><p>Based on the findings of the patient presented, we conducted a literature search of all the cases published in Spanish indexed journals (PubMed) and compared them, attempting to establish a suspicion profile that would result in the suspension of olmesartan and accelerate the complementary tests necessary to rule out other diagnoses.</p></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39843993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular research and population-based prospective cohort studies: as time goes by","authors":"M. Martin-Baranera","doi":"10.1016/j.hipert.2022.06.001","DOIUrl":"10.1016/j.hipert.2022.06.001","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40400191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respuesta a la carta al editor referida a «Importancia del conocimiento óptimo de los profesionales sanitarios en el diagnóstico inicial de la HTA para su valoración»","authors":"M. Serrat-Costa ,&nbsp;G. Coll de Tuero ,&nbsp;W. Ricart","doi":"10.1016/j.hipert.2022.05.002","DOIUrl":"10.1016/j.hipert.2022.05.002","url":null,"abstract":"","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54306018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}