Hipertension y Riesgo Vascular最新文献

{"title":"The predictive value of CRP/albumin ratio (CAR) in the diagnosis of ischemia in myocardial perfusion scintigraphy","authors":"M. Arefnia ,&nbsp;M. Bayat ,&nbsp;E. Hosseinzadeh ,&nbsp;E. Ahmadi Basiri ,&nbsp;M.A. Ghodsirad ,&nbsp;R. Naghshineh ,&nbsp;H. Zamani","doi":"10.1016/j.hipert.2025.01.001","DOIUrl":"10.1016/j.hipert.2025.01.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Ischemic heart disease (IHD) is the leading cause of mortality worldwide, and finding cheap and accurate screening tests is crucial. This study aimed to evaluate the predictive value of C-reactive protein (CRP)/albumin ratio (CAR) in the diagnosis of IHD using myocardial perfusion imaging (MPI).</div></div><div><h3>Methods</h3><div>In this cross-sectional study, a total of 112 patients were investigated to find any relationship between CAR and myocardial ischemia by using myocardial perfusion scintigraphy. Data were analyzed using SPSS, with a <em>P</em>-value below 0.05 considered statistically significant.</div></div><div><h3>Results</h3><div>Eighty-eight patients had normal MPI. Twenty-two patients had some degree of myocardial ischemia in MPI. The normal MPI and pathological MPI groups were similar in terms of sex, weight, smoking, family history of IHD, albumin levels, diabetes mellitus status, hyperlipidemia, and chest pain type. The CRP, and CAR means in the patients with myocardial ischemia were significantly higher than those with normal MPI.</div></div><div><h3>Conclusion</h3><div>Although the value of CAR was significantly higher in patients with myocardial ischemia compared to subjects with normal MPI and it was an independent predictor of IHD, the capability of CAR in diagnosing myocardial ischemia was not very strong with a sensitivity and specificity of about 60%.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 172-179"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practices of low value or unnecessary practices in vascular prevention","authors":"C. Brotons ,&nbsp;I. Moral ,&nbsp;J.M. García Abajo ,&nbsp;J. Caro Mendivelso ,&nbsp;O. Cortés Rico ,&nbsp;Á. Díaz ,&nbsp;R. Elosua ,&nbsp;D. Escribano Pardo ,&nbsp;M.M. Freijo Guerrero ,&nbsp;M. González Fondado ,&nbsp;M. Gorostidi ,&nbsp;M.M. Goya Canino ,&nbsp;M. Grau ,&nbsp;C. Guijarro Herraiz ,&nbsp;C. Lahoz ,&nbsp;E. Lopez-Cancio Martínez ,&nbsp;N. Muñoz Rivas ,&nbsp;E. Ortega ,&nbsp;V. Pallarés-Carratalá ,&nbsp;E. Rodilla ,&nbsp;P. Armario","doi":"10.1016/j.hipert.2025.01.002","DOIUrl":"10.1016/j.hipert.2025.01.002","url":null,"abstract":"<div><h3>Background</h3><div>Low-value practices are avoidable interventions that provide no health benefits. The objective of this study was to conduct a narrative review of the recommendations for practices of low value-care in vascular prevention.</div></div><div><h3>Methods</h3><div>A narrative review of all low value-care recommendations for vascular prevention published in the main European and North American scientific societies for clinical practice guidelines between 2014 and 2024 was carried out.</div></div><div><h3>Results</h3><div>A total of 38 clinical practice guidelines and consensus documents from international organizations in the United States, Canada, the United Kingdom, and Europe were reviewed, 28 of which included between 1 and 20 recommendations on practices of low value-care in vascular prevention. The total number of recommendations was 141. The American Heart Association is the society that offers the largest number of recommendations of low value-care, with 39 recommendations (27.7%) in 5 clinical practice guidelines (13.2% of the total guidelines with recommendations). The guideline for the management of arterial hypertension of the European Society of Hypertension is the guideline that concentrates the largest number of recommendations of low value-care in a single guideline, with 20 recommendations (14.2% of the total guidelines with recommendations).</div></div><div><h3>Conclusions</h3><div>There are more and more guidelines that explicitly describe diagnostic or pharmacological activities of low value-care or Do Not Do Class III or recommendation D. Some guidelines agree, but others show clear discrepancies, which can illustrate the uncertainty of the scientific evidence and the differences in its interpretation.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 129-146"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrative review: Isolated nocturnal hypertension – A frosted glass","authors":"J. Minetto ,&nbsp;G. Cerri ,&nbsp;W. Espeche","doi":"10.1016/j.hipert.2025.02.002","DOIUrl":"10.1016/j.hipert.2025.02.002","url":null,"abstract":"<div><div>The following article is a narrative review on isolated nocturnal hypertension, conducted up to July 2024, with a search for primary and secondary articles in MEDLINE, LILACS, and gray literature.</div><div>This review highlights aspects related to its current definition, epidemiology, and associated populations and risk factors, as well as specifics regarding its diagnosis, prognostic importance for target organ damage and cardiovascular events/mortality, and potential treatments.</div><div>This condition has particular aspects and, although it is not very common in the general population, it reaches high prevalence in some at-risk populations. To date, there is much debate and many issues to investigate regarding diagnostic aspects, as well as its heterogeneity and clinical significance, which indicate different prognoses. Therapeutic aspects are even more a matter of debate, necessitating future research.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 222-236"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144620762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between psychosocial stressors and hypertension and vascular risk","authors":"Q. Foguet-Boreu ,&nbsp;V. Abrines Bendayán ,&nbsp;R. Nadal ,&nbsp;L. Ayerbe García-Monzón ,&nbsp;P. Armario","doi":"10.1016/j.hipert.2025.06.001","DOIUrl":"10.1016/j.hipert.2025.06.001","url":null,"abstract":"<div><div>Psychosocial stress can result from a wide variety of causes and circumstances. The experience of stress is often unique and highly personal, but with common physiological responses. It is expected to increase in the modern world, which is undergoing rapid social, cultural and technological change. In this narrative review we present psychosocial factors impacting hypertension (HT) and vascular risk (VR) and propose strategies for detection and management of their main clinical consequences. Psychosocial stress more than doubles the risk of HT, with work-related stress and low socioeconomic status being the most related factors. The factors most strongly associated with increased VR were informal care of dependents, lower socioeconomic status, marital status (single, divorced or widowed) and loneliness. Individual and collective psychosocial stress prevention strategies may be crucial in reducing the prevalence of HT and VR.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 211-221"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statins and preeclampsia: An update from the Working Group on Hypertension in Women, Argentine Society of Hypertension","authors":"A.M. Ghelfi ,&nbsp;G. Miranda ,&nbsp;L.S. Voto ,&nbsp;J.M. Zilberman ,&nbsp;M.A. Del Sueldo ,&nbsp;F. Waisman ,&nbsp;M. Baroni ,&nbsp;M.V. Ferretti ,&nbsp;J.P. Moran ,&nbsp;A. Corrales-Barboza ,&nbsp;R. Mondino ,&nbsp;M.P. Pérez ,&nbsp;P.G. Irusta ,&nbsp;L. Meccia ,&nbsp;E. Martínez Marissi ,&nbsp;M.L. Baiche ,&nbsp;A.M. Delucchi ,&nbsp;P.D. Rodríguez ,&nbsp;N.F. Renna","doi":"10.1016/j.hipert.2025.03.001","DOIUrl":"10.1016/j.hipert.2025.03.001","url":null,"abstract":"<div><div>Hypertensive disorders of pregnancy (HDP) affect 5–10% of pregnancies. Preeclampsia (PE) is a severe complication of HDP, associated with high maternal, fetal, and neonatal morbidity and mortality. The pathophysiology of PE involves endothelial dysfunction, vasoconstriction, and impaired placental perfusion, leading to systemic inflammation and multi-organ dysfunction. It has been suggested that statins, traditionally contraindicated during pregnancy, could play a role in this context. Some studies propose that pravastatin, a hydrophilic statin, may not have the same teratogenic effects as lipophilic statins, potentially improving maternal vascular status and significantly reducing the risk of PE. Considering this, the Working Group on Hypertension in Women of the Argentine Society of Hypertension undertook a review of the topic and its current implications.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 147-155"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of antihypertensive medication adherence and associated factors in India: A systematic review and meta-analysis","authors":"B. Pal ,&nbsp;A. Dutta ,&nbsp;V. Chaudhary ,&nbsp;S. Kumari ,&nbsp;S. Meenakshi ,&nbsp;K. Murti","doi":"10.1016/j.hipert.2024.11.005","DOIUrl":"10.1016/j.hipert.2024.11.005","url":null,"abstract":"<div><h3>Background</h3><div>Non-adherence to antihypertensive medication is a key factor contributing to uncontrolled blood pressure and the subsequent complications of hypertension. Despite its importance, there is a lack of data regarding the prevalence of and factors associated with non-adherence to medication among individuals with hypertension in India. This review aimed to assess medication adherence rates among hypertensive patients in India and identify the factors influencing non-adherence.</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted across PubMed, Scopus, Embase, and Google Scholar. Studies reporting medication adherence/non-adherence to antihypertensive medications in India, using the Morisky Medication Adherence Scale (MMAS), with publication dates up to July 2023, were included.</div></div><div><h3>Results</h3><div>Twelve studies were included, involving a total of 3164 participants. The pooled rate of medication adherence to antihypertensive medications in India was determined to be 15.8% (95% CI: 4.4; 43.4). The important factors associated with non-adherence included higher age, medication regimen complexity, low socioeconomic status, low education levels, uncontrolled blood pressure, and comorbidities.</div></div><div><h3>Conclusions</h3><div>The adherence rate to antihypertensive medication was observed to be quite low. Therefore, it is imperative to enhance the rate of medication adherence among individuals with hypertension in order to attain effective blood pressure control and reduce the burden of non-communicable diseases.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 156-164"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and management of diastolic dysfunction in arterial hypertension","authors":"P. Blanch,&nbsp;R. Freixa-Pamias","doi":"10.1016/j.hipert.2025.06.002","DOIUrl":"10.1016/j.hipert.2025.06.002","url":null,"abstract":"<div><div>Diastolic dysfunction (DD) refers to impaired relaxation or filling of the ventricles during the diastolic phase of the cardiac cycle. Left ventricular (LV) DD is common in hypertensive individuals and is associated with increased morbidity and mortality, particularly heart failure with preserved ejection fraction (HFpEF). The pathophysiology of DD involves alterations in cardiac structure and function, neurohormonal activation, and vascular stiffness. Diagnosis is primarily based on echocardiography, and there are no specific treatment guidelines. Recently, treatments such as sodium-glucose cotransporter 2 inhibitors (SGLT2i), GLP-1 receptor agonists, and finerenone have emerged, which may offer benefits in diastolic dysfunction and HFpEF. This review aims to present the pathophysiological mechanisms of DD in hypertension (HTN), its diagnosis, and its treatment.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 237-246"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension, inflammation and vascular risk in inflammatory rheumatic diseases","authors":"D. Cerdà ,&nbsp;D. Reina ,&nbsp;H. Corominas ,&nbsp;P. Armario","doi":"10.1016/j.hipert.2025.04.001","DOIUrl":"10.1016/j.hipert.2025.04.001","url":null,"abstract":"<div><div>Vascular risk is higher in patients with rheumatoid arthritis, spondyloarthritis, and psoriatic arthritis than in the general population. In addition to classical vascular risk factors, chronic inflammation plays a crucial role in increasing this risk. In rheumatoid arthritis, the prevalence of hypertension is 41%. Moreover, the prevalence of hypertension has been associated with the duration of spondyloarthritis, as well as the presence of severe psoriasis in psoriatic arthritis. Although some drugs used in the treatment of inflammatory arthritis, such as NSAIDs, glucocorticoids, and Jakinibs, have been associated with an increased vascular risk, their ability to reduce inflammatory activity contributes to a decreased vascular risk in these patients. These drugs should be used with caution, and risk stratification should be performed in patients with vascular risk factors.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 195-203"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood pressure variability. Impact on antihypertensive treatment","authors":"A. de la Sierra","doi":"10.1016/j.hipert.2025.03.002","DOIUrl":"10.1016/j.hipert.2025.03.002","url":null,"abstract":"<div><div>Blood pressure oscillations during different time scales, known as blood pressure variability, have become a focus of growing scientific interest. Blood pressure variability can be measured at long-term (seasonal variability or visit-to-visit), at mid-term (consecutive days or weeks) or at short-term (day-night differences or changes induced by other daily activities and conditions). An increased blood pressure variability, either at long, mid, or short-term is associated with a poor cardiovascular prognosis independently of the amount of blood pressure elevation. There is scarce evidence on the effect of different antihypertensive treatments on such variability, but some observational and interventional studies suggest that reduction in blood pressure variability, and indirectly, increase of the time in therapeutic range, has a beneficial effect on cardiovascular prognosis. Antihypertensive drugs with a longer duration, and specifically, some calcium channel blockers, might represent an advantage.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 204-210"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular risk markers in apparently healthy young adults: Evaluation according to optimal or non-optimal office blood pressure","authors":"W. Espeche ,&nbsp;O.A. Pinilla ,&nbsp;G. Cerri ,&nbsp;N. Stavile ,&nbsp;J. Minetto ,&nbsp;M.R. Salazar ,&nbsp;I.L. Ennis","doi":"10.1016/j.hipert.2024.11.006","DOIUrl":"10.1016/j.hipert.2024.11.006","url":null,"abstract":"<div><h3>Background</h3><div>Blood pressure (BP) is linearly related to the incidence of cardiovascular disease from values as low as 115/75<!--> <!-->mmHg, even at young ages. A particularly concerning issue is the decrease representation of optimal BP among children and youth. The mechanisms by which minimal elevations in BP increase cardiovascular risk are not defined. The limitations of office BP measurements could be a possible explanation since 24-h ambulatory measurements (ABPM) better detect the risk of future cardiovascular events. Therefore, we aimed to compare healthy normotensive undergraduate students with optimal vs. non-optimal BP: ABPM, the cardiometabolic risk profile, and echocardiographic characteristics.</div></div><div><h3>Methods</h3><div>Medical students from La Plata voluntarily completed a survey to collect personal and family data on cardiovascular risk factors. Subsequently, anthropometric, BP (office and ABPM), and echocardiography determinations were recorded. Cholesterol, triglycerides, and glucose were measured in fasting blood samples. Statistical analyses were performed blinded, using SPSS software.</div></div><div><h3>Results</h3><div>Data from 135 students were analyzed (76% female, age 22.5<!--> <!-->±<!--> <!-->3.5 years). Mean office BP was 114.5<!--> <!-->±<!--> <!-->10.4 and 73.7<!--> <!-->±<!--> <!-->7.5<!--> <!-->mmHg. Forty percent of students had non-optimal BP (61% females) showing significantly higher BP values in all ABPM periods and higher left ventricular mass index, cardiac wall thicknesses, fasting glucose, TyG index, TG/HDL-c ratio. Seven students met diagnostic criteria for nocturnal hypertension, six of whom were in the non-optimal BP group (11.1% vs 1.2%).</div></div><div><h3>Conclusions</h3><div>Therefore, our study shows that apparently healthy young individuals with non-optimal BP, even if not hypertensive, exhibit differences in several cardiovascular risk markers compared to those with optimal BP.</div></div>","PeriodicalId":39403,"journal":{"name":"Hipertension y Riesgo Vascular","volume":"42 3","pages":"Pages 165-171"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}