Medicine Today最新文献

{"title":"Causes of Infertility among the Couples Who are Attending the Infertility OPD of BSMMU","authors":"Shaheen Ara Anwary, M. N. I. Mondal, M. Karim, Md. Mostafizur Rahman, M. Alfazzaman, Zeenat Mahzabin, M. Rahman, Amirun Nahar","doi":"10.3329/medtoday.v35i1.64934","DOIUrl":"https://doi.org/10.3329/medtoday.v35i1.64934","url":null,"abstract":"Introduction: Infertility may be defined as inability to conceive within one year of unprotected regular coitus. Approximately 85 – 90% of healthy young couples conceive within 1 year, most within 6 months1. Infertility therefore affects approximately 10 – 15% of couples and represents an important part of clinical practice2. A general classification of causes of infertility are male 35 – 40%, female 40 – 50% (tubal 25%, ovulatory 20% and cervical 1 – 2%), sexual 10% and unknown 10%3. More than one factor per couple accounts for the total percentage appearing to exceed 100%.\u0000Objective: To assess the determinants of infertility among the infertile couples both male and female attending the outpatient department of infertility unit of the department of obstetrics and gynaecology of Bangabandhu Sheikh Mujib Medical University , Shahbagh, Dhaka.\u0000Materials & Methods: This prospective observational study was conducted in the Infertility unit, Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, during the period from 01.07.2018 to 31.12.2021. Five hundred infertile couples were recruited from the out-patient department of infertility unit who came to take treatment for their infertility problem. Data were collected from the couples by data collection sheet and the data were plotted in the tables. The data were analyzed by SPSS program, version 28.\u0000Results: The socio-demographic characteristics of the study subjects (n = 500).Husbands age group was 22 -55in years, Mean ± SD (34.0 ± 5.9). Age of the female partners was 18 – 44 years, mean ± SD (27.1 ± 5.2). Majority of the female study subjects had secondary level of education (49.4%), where as in male study subjects secondary level of education was 30.4%, followed by graduates (29.6%). Occupation of female partners was mostly housewife = 395 (79.0%), occupation of male partners was mostly service = 356 (71.2%). Regarding religion, Muslims were 476 (95.2%), others were 24 (4.8%). Majority of them hailed from rural area (62%). According to BMI, majority of female were overweight (56%). Among the respondents, majority of them had primary infertility (59.8%) and the rest (40.2%) had secondary infertility. Regarding hormonal status of infertile women, most of them (94%) had serum FSH below normal (< 3U/L), serum LH below normal (< 2U/L) in 96% patients, Serum TSH above normal (>4.5 mU/L) in 49.0% patients, serum FT4 above normal (>21 pml/L) in (60.8%) patients, serum Prolactin level above normal (>630 mU/L) in 27.8) patients. Diabetes: In male = 28 (5.6%).Mumps: In male = 7 (1.4%). Chicken pox: In male = 18 (3.6%). Hypertension: In male = 10 (2.0%). Orchitis: In male = 6 (1.2%). Personal history of husband: Smoking = 129 (25.8%). In male patients, Testosterone level normal (10 – 30 nmol/L) in 133 (26.6%) patients and above normal (>30 nmol/L) in 367 (73.4%) patients. The semen analyses of the husbands of the infertile female patients shows, quality of semen po","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91379876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study between Metal Clip Application and Suture Ligation of Cystic Duct in Laparoscopic Cholecystectomy","authors":"Mahmudul Hasan Chowdhury, Md Aziz Ullah, M. Z. Rahman, Sadia Rahman, Nazmul Arefin, Md. Ashraful Islam","doi":"10.3329/medtoday.v35i1.64935","DOIUrl":"https://doi.org/10.3329/medtoday.v35i1.64935","url":null,"abstract":"Introduction: Laparoscopic cholecystectomy has been performed for decades and is a fairly standardized procedure throughout the world. Occlusion of the cystic duct is popularly done with the help of metal clips. There are many other techniques described in the literature to deal with occlusion of the Cystic Duct. Suture ligation of the duct is one such way.To evaluate the effectiveness in term of cost, safety, and complication in occlusion of cystic duct with suture ligation compared to clip application.\u0000Materials and Methods: A prospective cross sectional comparative study was carried out From June 2020 to November 2020. Data were collected from 80 patients undergone laparoscopic cholecystectomy for Gall stone diseases. 40 patients were enrolled in each group by consecutive purposive sampling. Complete history was taken. Thorough clinical examination was done. Relevant investigations report was collected.\u0000Results: Female patients were predominant in both groups and most of the patients were underweight. Mean time for ligation was more in occlusion of cystic duct with clip application. Bile leakage was found and duration of drain in situ was more in occlusion with clip application. Cost was high in occlusion with clip application.\u0000Conclusion: : Time for ligation, Bile leakage, mean duration of drain in situ (days), and cost of Cystic Duct occlusion and port closure were significantly higher in Laparoscopic Cholecystectomy with conventional Clip application of Cystic Duct group in comparison to Laparoscopic Cholecystectomy with ligation of the Cystic duct with no-1vicryl by extra corporeal knotting group.\u0000Medicine Today 2023 Vol.35(1): 27-30","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89897420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors in Post Operative Wound Infections Following Elective Abdominal Operations","authors":"S. Akramuzzaman, M. S. Islam, A. Galib","doi":"10.3329/medtoday.v35i1.64943","DOIUrl":"https://doi.org/10.3329/medtoday.v35i1.64943","url":null,"abstract":"Introduction: Surgical site infections are common post operative complication and cause significant post operative morbidity and mortality, and have serious consequences for outcomes and costs. Different risk factors are involved, including age, sex, smoking, nutrition, diabetes, pre existing illness, pre operative hospital stay time, pre operative shaving, level of surgeon, length of incision, duration of operation, per operative blood transfusion, wound drainage and nature of wound. The objective of this study was to determine the risk factors affecting abdominal surgical site infections and their rate at Dhaka Medical College & Hospital, a major referral teaching hospital in Bangladesh.\u0000Objectives: were to identify risk factors in post operative wound infections following elective abdominal surgery.\u0000Materials and Methods: A Cross sectional type of observation study was carried out among 153 patients in Department of Surgery, Dhaka Medical College Hospital, Dhaka from January 2008 to December 2009.\u0000Results: Patients (n = 153) who had undergone elective surgery were studied and the relationships among variables were analyzed by Student's t and Chi-square tests. To test the independence of the risk factors, the significant variables (p _.05) in the univariate analyses were entered into a stepwise logistic regression equation. Data were collected through pre and postoperative examinations. The subjects were followed till discharge. Of the 153 patients, 13 suffered from SSI (8.5%). Among the infections superficial SSI was in 8 cases (61.54%), deep SSI in 3 cases (23.08%), and organ/space SSI in 2 (15.38%) cases. There were 14 different variables in study to determine the risk factors. In univariate analysis ten risk factors were identified: age, underweight, diabetes, ASA score, pre operative hospital stay, per operative blood transfusion, length of incision, duration of operation, wound drain and contaminated wound. And in multivariate analysis duration of operation, diabetes mellitus and ASA score appeared to be independent risk factors for wound infection.\u0000Conclusion: The total elimination of wound infection is not possible, a reduction in the infection rate to a minimal level could have significant benefits in terms of both patient comfort and medical resources used. The SSI may be reduced to a more acceptable level by reducing the average operation time to less than 2 hours, pre operative hospital stay, and by reducing contamination during operation and wound drainage. Furthermore post operative study in large scale is recommended.\u0000Medicine Today 2023 Vol.35(1): 56-62","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78882222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrum of Upper Gastrointestinal Endoscopic Findings in Patients with Dysphagia: A Study of 147 Cases","authors":"Ramesh Lamichhane, M. Saha, G. Yadav","doi":"10.3329/medtoday.v34i2.61429","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61429","url":null,"abstract":"Introduction: This retrospective descriptive cross-sectional study was done to see upper gastrointestinal endoscopic findings in patients presenting with dysphagia.\u0000Materials and Methods: Reports of patients undergoing upper gastrointestinal endoscopy were retrieved from endoscopy records. Data regarding age, gender, and endoscopic features and impressions were collected. The data analysis was done using IBM SPSS® v21 (IBM, Armonk, New York). Frequency, proportions, mean ± SD, and range were calculated.\u0000Results: Out of 147 participants, the mean age of the participants was 53.46 ± 15.99 years. There was an equal proportion of participants of each gender (50.3% female and 49.6% male). The prevalence of endoscopic abnormalities was 93.8%. Most of the participants had carcinoma esophagus (38.7%, 57) followed by gastritis (35.3%, 52), gastric polyp (10.8%, 16), and duodenitis (8.8%, 13).\u0000Conclusion: Dysphagia is an alarming symptom that warrants prompt evaluation. With diagnostic and therapeutic value, upper GI (gastrointestinal) endoscopy remains a rapid initial effective tool in the evaluation of patients with dysphagia.\u0000Medicine Today 2022 Vol.34(2): 136-139","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84102298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tibial Plateau Injury: Mechanical Implantation with Plates and MIPO Approach Tertiary Level Hospital in Bangladesh","authors":"Md. Abdur Rashid, S. Ahmed, Reza Nasim Ahmed","doi":"10.3329/medtoday.v34i2.61421","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61421","url":null,"abstract":"Introduction: Proximal tibial injuries are challenging to treat because of articular surface involvement, frequent congestion, and precariat soft tissue conditions, particularly after high-energy traumas. The treatment is intended to restore the unity of the joint surfaces that supports the typically depressed tibial plateau cartilage, use a strong device to stabilize the fracture and prevent further damage, to enable early recovery. We describe our treatment approach, using closed or open decrease and internal fixation, polyaxy plates, automatic bone-gloss, or other osteoconductive material enhanced by autologous platelet gel, where required. Surgery depends on the timing of the soft tissue and is typically done directly or under the guidance of a skilled surgeon using tissue-sparing techniques as much as feasible.\u0000Materials and Methods: A prospective analysis of all (n=58) proximal tibial fractures at the Islamic Bank Medical College Hospital and multicentral tertiary level hospital, Rajshahi, Bangladesh, from January 2019 to June 2021. Patient data were collected by evaluating hospital diagrams, office records, preoperative and after operative radiograph. Fractures were classified in the classification of OTA/AO. In 78 % of the 12-month post-surgery group, the Rasmussen score's evaluation of functional outcomes found positive to outstanding results.\u0000Results: Total Number of patient n=58 tibial proximal (intra-articular) fractures have been identified. The mean age was 43 years (range 19–79) at surgery, whereas women and 39 men were 19. The most frequent injury mechanism was linked to traffic accidents (RTA), representing 75% of cases. 09 (18.4%) AO/OTA types A, 31 (53.5%) AO/OTA type B and 18, (31.1%) AO/OTA type C fractures have been identified. Most (90 %) cases (44) were treated with open reduction and internal fixation, using polyaxially anatomical angular stability locking Plates.\u0000Conclusions: Internal fixing using locking plates, following the MIPO principles (Minimally Invasive Percutaneous Osteosynthesis), offers an acceptable reduction of fractures with excellent outcomes for the medium-term clinical results.\u0000Medicine Today 2022 Vol.34(2): 93-98","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81773337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Changes in Serum Calcium Level during Postmenopausal Period of Women in Bangladesh","authors":"Susmita Nargis, Rasel Bhuyan, H. L. Roy, Kazi Muhammad Mahmudul Hasan, Pijush Chakraborty","doi":"10.3329/medtoday.v34i2.61433","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61433","url":null,"abstract":"Introduction: The study was designed to evaluate the serum calcium levels may be altered in postmenopausal women.\u0000Materials and Methods: This case control study was carried out in the Department of the Biochemistry, Mymensingh Medical College, Mymensingh, from January 2015 to December 2015. The subjects were selected on the basis of inclusion and exclusion criteria by purposive (non-random) method. This study included 50 postmenopausal women as case.\u0000Results: The results were compared with 50 apparently healthy premenopausal women as control. All statistical analysis was done by SPSS windows package. The values were expressed as Mean ± SD. Statistical significance of difference between two groups were evaluated by using student’s unpaired t-test. Serum calcium level was analyzed. Serum calcium was determined by using colorimetric method. The mean value of serum calcium was 8.59±1.02 (mg/dl) respectively in group B (Case) and 6.36 ± 1.06 (mg/dl ) in group A(Control). The levels of serum calcium was significantly decreased in group B.\u0000Conclusion: Menopause has an effect on serum calcium which leads to increased risk of development of osteoporosis. The present study may facilitated the clinicians and gynecologists to update their knowledge in regard to serum calcium level of women associated with menopause.\u0000Medicine Today 2022 Vol.34(2): 150-152","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84359114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Platelet Count on Non-ST Elevation Myocardial Infarction: In-Hospital Outcome","authors":"Md Zahidur Rahman, S. Saha, Md Ikhtiar Hassan Khan, Swadesh Kumar (SK) Chakrovortty, S. A. Al Mamun","doi":"10.3329/medtoday.v34i2.61427","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61427","url":null,"abstract":"Introduction: Incidence of ACS is increasing in developing countries like Bangladesh. Many factors can influence in hospital outcome of NSTEMI Patient. Platelet count is one of them. The aim of present study was by measuring platelet count to detect the severity of NSTEMI patients and their in hospital outcome.\u0000Objective: The aim of present study was to observe the impact of platelet counts on in hospital outcome of NSTEMI.\u0000Materials and Methods: The study was conducted in Shahid Sheikh Abu Naser Specialized Hospital, Khulna from January 2021 to November-2021. NSTEMI Patient Presented within 24 hours of chest pain was included in this study. Data were collected by direct interview from Patient and venous blood was drawn for platelet count. Continuous data were expressed as mean ±SD. Categorical data were analyzed with x2 test. Student’s ‘t’ test was used for analysis of Continuous variables. Comparision between groups was done by unpaired t-test. Multiple logistic regression analysis was done to determine the association between lower platelet counts and adverse hospital events in NSTEMI patients. P-values <0.05 were be considered statistically significant.\u0000Results: 100 Patients are included in this study. They are devided into two groups. Group-1 having platelet count <200000/cmm) and Group-II having platelet count > 200000/cmm. Bleeding, Q-wave MI, arrythmia and heart failure were significantly (P<0.05) higher in group-I but stroke and death were similar in both groups.\u0000Conclusion: Lower platelet count in NSTEMI patient is associated with adverse in-hospital outcome.\u0000Medicine Today 2022 Vol.34(2): 125-129","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85640012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Activity (ADL) Modification on Reduction of Pain in Patients with Chronic Non-Specific Low Back Pain","authors":"Khandaker Md Kamrul Islam, Md. Ahsanul Hoque, M. Akter","doi":"10.3329/medtoday.v34i2.61431","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61431","url":null,"abstract":"Introduction & Objective: : Low back pain is the commonest cause of activity limitations and absence of work in developing country like Bangladesh. The aim of this study was to chalk out the association between ADL modification with chronic low back pain.\u0000Materials & Methods: : This Randomized Clinical Trial was performed in the Department of Physical Medicine and Rehabilitation, JRRMCH, Sylhet. Eighty patients of 30 to 60 years old, fulfilling the selection criteria were included in this study. Patients were divided into two groups after randomization by lottery method. Patients of Group-A were treated with NSAID, Anti-ulcerant & Activity (ADL) Modification while patients of Group-B were treated with NSAID and Anti-ulcerant only. Patients of both groups were treated for six weeks. Main outcome measures were Subjective Pain Intensity Score, VAS, Tenderness Index, Disability due to pain, Spinal Mobility Index and Oswestry Disability Index.\u0000Results: Majority of the patients of both groups were 30 to 40 years old (52.5% in Group-A and 47.5% in Group-B). Males were predominant in both groups. While majority belongs to middle socio-economic class, occupationally farmers were majority in both groups (22.5% in Group-A and 20% in Group-B). VAS was better in patients who received instructions about activity (ADL) modification than those who did not receive them. Subjective Pain Intensity Score and Tenderness Index improved in both groups but their difference was not statistically significant. Disability due to Pain and Spinal Mobility Index, both the variables improved at the end of 3rd week and their difference was statistically significant (P<0.05).\u0000Conclusion: From the study it can be concluded that Activity (ADL) Modification helps to reduce pain in patients with chronic non-specific low back pain.\u0000Medicine Today 2022 Vol.34(2): 140-144","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80355736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Male Infertility among Married Couples in a Tertiary Hospital in Bangladesh","authors":"Shaheen Ara Anwary, M. Alfazzaman, Zeenat Mahzabin","doi":"10.3329/medtoday.v34i2.61434","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61434","url":null,"abstract":"Introduction: Infertility may be defined as a lack of conception after 1 – 2 years of unprotected coitus. In a normal population approximately 60 % of couples will achieve pregnancy within 6 months, 80 % by 12 months, and 90 % by 18 months leaving approximately 10 % of couples arbitrarily classified as infertile. A general classification of causes of infertility are male 35 – 40 %, female 40 – 50 %, sexual 10 % and unknown 10 %.\u0000Objective: To see the determinants of male infertility among the infertile couples who attending the outpatient department of infertility unit of the department of obstetrics and gynaecology of Bangabandhu Shiekh Mujib Medical University, Shahbag, Dhaka.\u0000Materials and Methods: This prospective observational study was conducted in the Infertility unit, Department of Obstetrics and Gynaecology, Bangabandhu Shiekh Mujib Medical University (BSMMU), Dhaka, during the period from 31.10.2016 to 21.03.2018. 500 infertile male patients were recruited from the out-patient department of infertility unit who came to take treatment for their infertility problem. They were analyzed by data collection sheet and the results were plotted in the table.\u0000Result: The socio-demographic characteristics of the study subjects (n = 500).Husbands age group was 22 -55in years, Mean ± SD (34.0 ± 5.9). Educational level of male partners was, no education = 5 (1.0%), primary = 27 (5.4%), secondary = 152 (30.4%), graduate = 148 (29.6%), postgraduate = 74 (14.8%), 0thers = 94 (18.8%). Occupation of male partners was, unemployed = 6 (1.2%), service = 356 (71.2%), business = 138 (27.6%). Diabetes: In male = 28 (5.6%).Mumps: In male = 7 (1.4%). Chicken pox: In male = 18 (3.6%). Hypertension: In male = 10 (2.0%). Orchitis: In male = 6 (1.2%). Personal history of husband: Smoking = 129 (25.8%). In male patients, Testosterone level normal (10 – 30 nmol/L) in 133 (26.6%) patients and above normal (>30 nmol/L) in 367 (73.4%) patients. The semen analysis of the husbands of the infertile female patients.In quality of semen poor (<4%) in 305 (61%) patients. Regarding semen quality, oligospermia (<15 million/ml) was in 480 (96%) patients and azospermia (0% count) in 20 (4%) patients. In case of motility of sperms, rapid linear below normal (<50%) was in 90 (18%). In case of slow linear (SL), below normal (<15%) in 324 (64.8%) patients. In case of morphology of sperms, below normal (<14million/ml) in 25 (5%) patients.\u0000Conclusion: This study shows a significant percentage of male are suffering from infertility. There is considerable association of determinants of infertility among the male partners.\u0000Medicine Today 2022 Vol.34(2): 153-156","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80795906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Lipid Profile in Different Types of Steroid Sensitive Idiopathic Relapsing Nephrotic Syndrome in Children during Active Disease and Remission","authors":"SM Shamsul Hoque, Md. Ashraful Islam, T. Akter, R. Roy, Md. Habibur Rahman","doi":"10.3329/medtoday.v34i2.61424","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61424","url":null,"abstract":"Introduction: Nephrotic syndrome is a disease of relapse and remission. Relapse rate is more than 80%. Hyperlipidemia and hypoalbuminemia are important characteristic of nephrotic syndrome. Hyperlipidemia persist even after remission of disease in frequent relapse nephrotic syndrome possibly due to frequent attack of disease and frequent use of steroid. Hyperlipidemia causes premature atherosclerosis, progressive renal injury leading to chronic renal failure, cardiac complications (myocardial infarction, hypertension), cerebrovascular disease and frequent relapse of nephrotic syndrome.\u0000Objectives: The aim of study was to see the lipid profile and comparison of lipid profile among different types of steroid sensitive idiopathic relapsing nephrotic syndrome during active disease and in remission.\u0000Materials and Methods: A cross sectional study included 120 ( 40 in each group) children aged 2-16 years with steroid sensitive idiopathic relapsing nephrotic syndrome patients who were admitted or attended in out patients department (OPD) in paediatric nephrology department Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, during December 2014 to December 2015. They were clinically examined and fasting lipid profile was done in each case during active disease and after one month of urinary remission. The study population were divided into three groups- Infrequent relapse nephrotic syndrome (IFRNS), frequent relapse nephrotic syndrome ( FRNS ) and steroid dependent nephrotic syndrome (SDNS) based on clinical response.\u0000Results: Total patients were 120 (40 in each group). The study showed a male predominance with a male to female ratio 2.24:1, male patients were 69%, female 31%. In all cases, there were increased mean total cholesterol, low density lipoprotein ( LDL ) , triglyceride (TG) and high density lipoprotein (HDL) was normal during active disease, more raised in FRNS and SDNS.There was significant decrease in the mean level of total cholesterol, LDL and triglyceride during remission ( p <0.001). Cholesterol became normal but triglyceride and LDL remained elevated even after one month of urinary remission in FRNS and SDNS.\u0000Conclusion: Hyperlipidemia persist during remission of steroid sensitive relapsing nephrotic syndrome. Children with FRNS and SDNS should be addressed with lipid lowering medication, healthy foods and healthy life style. Multicenter prospective studies with larger sample are needed for validating the findings of the present study.\u0000Medicine Today 2022 Vol.34(2): 111-116","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80410599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}