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{"title":"Comparative Study of Radiation Exposure of Patients undergoing Transradial and Transfemoral Coronary Angiogram and Percutaneous Coronary Intervention","authors":"Forhad Karim Mazumder, K. Mahmood, Abul Hasnat Md Jafar, Enamul Hoq, Rubaba Sharmin","doi":"10.3329/medtoday.v34i2.61428","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61428","url":null,"abstract":"Introduction: Coronary artery disease (CAD) is now the leading cause of death worldwide. Percutaneous coronary interventions (PCIs) are an important group of technologies for the diagnosis and treatment of patients with CAD. PCI is usually performed using the transfemoral (TF) approach but the transradial (TR) approach has been increasingly used as an alternative to TF approach due to less vascular complications, earlier ambulation and improved patient comfort. Accurate assessment of radiation exposure during PCI is paramount important as radiation has many short and long term hazards. TR and TF route has distinct advantages and disadvantages. But in respect of radiation exposure of patients there are controversial evidence between TR and TF approach.\u0000Objective: To compare the radiation Exposure in patients with percutaneous coronary intervention by TR and TF approach.\u0000Materials and Methods: This prospective observational comparative study was conducted in the National Institute of Cardiovascular Diseases, Dhaka, from June 2015 to May 2016. A total of 200 patients were selected and categorized into two groups (Group I= Trans radial, n =100) and (Group II = Trans femoral, n= 100). Again divided into subgroups (group Ia, trans radial CAG = 70, group IIa, trans radial PCI =30) and (group IIa, trans femoral CAG =70, group IIb, trans femoral PCI = 30). Then different outcome variables were evaluated and compared.\u0000Results: Patient demographics were the same in both groups. Fluoroscopy time during TR and TFCAG and PCI was (4.4.±1.6 min vs 4.1±3.9 min, p=0.61) and (11.7±1.3 min vs 11.1±1.5 min, p=0.13) respectively. Regarding radiation dose during TR and TF coronary angiogram, Dose area product(DAP) were (2732±1195.5 mGym2vs 2434±488.0 mGym2, p=0.07&) and Air Kerma (AK) were (307.6 ±112.2 mGy vs 283.7±48.5 mGy, p=.10) with statistically no significant difference of radiation dose (DAP and AK) between two groups. Utilization of Contrast volume during TR and TF angiogram (64.8±8.9 vs 68.2±7.5, p=0.01) were less in trans radial group. Also Utilization of Contrast volume in TR-PCI and TF- PCI (168.0±13.0 vs 177.7±19.9 ml ,p=0.03) were less in trans radial PCI.\u0000Conclusion: The basis of the results, no significant differences were found in patient of radiation dose in both TR and TF group. Furthermore utilization of contrast volume was lower in trans-radial CAG and PCI. Trans radial CAG and PCI can be performed with the same safety as for the trans femoral approach.\u0000Medicine Today 2022 Vol.34(2): 130-135","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85748922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination of Thyroxine with Vitamin B12 on Motor Nerve Conduction Study of Ulanr Nerve in Newly Diagnosed Hypothyroid Female","authors":"Farjana Ahmed, N. Sultana, Md Arifuzzaman Chowdhury, S. Banik, K. Saha, Mahaboba Rahman","doi":"10.3329/medtoday.v34i2.61425","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61425","url":null,"abstract":"Introduction: Combination of thyroxine with vitamin B12 can improve the motor nerve conduction study of ulnar nerve in newly diagnosed hypothyroid female.\u0000Objectives: To observe the combined effects of thyroxine with vitamin B12 on motor nerve conduction study of ulnar nerve of newly diagnosed hypothyroid female\u0000Materials and Methods: This prospective interventional study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC) between July’ 2015 to June’ 2016 on 40 newly diagnosed hypothyroid female. Among them, 20 hypothyroid patients received only thyroxine (HT-T4 ) and another 20 hypothyroid patients received combined therapy of thyroxine with vitamin B12 (HT-C) for 90 consecutive days. Motor 2 nerve conduction study of ulnar nerve was studied to observe the electrophysiological status and vitamin B12 level was also estimated to observe its level by using standard method. The statistical analysis was done by ANOVA test, paired, independent sample ‘t’ test and Chi-square (χ 2 ) test as applicable.\u0000Results: In this study, latency was significantly decreased, amplitude and NCV were significantly increased in motor functions of ulnar nerve of hypothyroid patients after 90 days supplementation of combined therapy of thyroxine with vitamin B12 in comparison to those of their pre-supplemented state and also to those of patients with only thyroxine treatment.\u0000Conclusion: The combination of thyroxine with vitamin B12 can reduce the symptoms of hypothyroid neuropathy and accelerate the nerve conduction velocity of motor functions of ulnar nerve more efficiently than the treatment with thyroxine alone.\u0000Medicine Today 2022 Vol.34(2): 117-120","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86937772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprotection of Hepatitis B in Children with Steroid Sensitive Nephrotic Syndrome","authors":"Md. Ashraful Islam, T. Akter, Iftekhar Ul Hoque Khan","doi":"10.3329/medtoday.v34i2.61422","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61422","url":null,"abstract":"Introduction: Children with Steroid sensitive nephrotic syndrome is associated with lower seroconversion of hepatitis B vaccine due to prolonged period of proteinuria, prolonged period of steroid therapy\u0000Objective: The primary aims of this study was to assess the seroconversion rate in children with steroid sensitive nephrotic syndrome (SSNS) who were previously vaccinated against hepatitis B and to compare with the titre of vaccinated healthy children. The secondary aims was to study the association of antiHBs titre in different clinical types of diseases and comparison of persistant antibody titre after prolong post vaccinal duration in both nephritic syndrome and control group.\u0000Materials and Methods: This cross sectional study was carried out in the department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2014 to June 2015. A total of 75 vaccinated Children against hepatitis B aged 1 to 12 years of both sex suffering from steroid sensitive nephrotic syndrome were included in this study. Seventy five healthy children against hepatitis B were taken to compare the immunogenecity of hepatitis B vaccine as comparison group.\u0000Result: Out of seventy five children with steroid sensitive nephrotic syndrome (SSNS) 51(68%) were male and 24 (32%) were female. Most of the patients belonged to 2-4 year group (39.6%) and of them 42% had 1st attack. In comparison group most of the healthy children belonged to 2-4 year age group 22(28.2%). In nephrotic syndrome group, majority(57.3%) of the patients with nephrotic syndrome had antibody titre <10 miU/ml( not seroprotected). On the contrary 78.7% healthy control were seroprotected (antibody titre >10 miU/ml)and this difference was significant (p value =<0.001). In nephrotic syndrome group significant titre was present in 2-4 years post vaccinal duration which also declined after 9-10 years post vaccinal duration group . In healthy control group significant titre was present in 2-4 years post vaccinal duration group which also declined gradually after increasing post vaccinal duration.\u0000Conclusion: In nephrotic syndrome group significant titre was present in 2-4 years post vaccinal duration which also declined after 9-10 years post vaccinal duration group. In healthy control group significant titre was present in 2-4 years post vaccinal duration group which also declined gradually after increasing post vaccinal duration.\u0000Medicine Today 2022 Vol.34(2): 99-105","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84926321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ST Segment Score on Initial Electrocardiogram (ECG) as a Predictor of In-Hospital Outcome of ST-Elevated Myocardial Infarction (STEMI) Patients","authors":"Md Mahmudul Karim, HI Lutfur Rahman Khan, M. Faruk, Mohammad Addus Salam","doi":"10.3329/medtoday.v34i2.61420","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61420","url":null,"abstract":"Introduction: The process of myocardial infarction progresses over several hours and therefore most patients present when it is still possible to salvage myocardium. ECG is usually a sensitive and specific way of confirming diagnosis. ST segment score (STSS) in myocardial infarction is emphasized but not often quantified. HJ Wellens gave cutoff for STSS in anterior wall MI (AWMI)of 12 mm and inferior wall MI (IWMI)of 7 mm. In this study the predictive value of ST Segment Score (STSS) with patients of STEMI on admission ECG & after thrombolysis had been assessed.\u0000Objectives: Identify patients at higher risk early in the course of their hospital admission & correlation of initial ECG and post thrombolysis ECG regarding clinical outcome.\u0000Materials and Methods:Considering inclusion and exclusion criteria 112 patients admitted in CCU, DMCH during october 2007 to september 2008 were studied of which 64 were inferior STEMI and 48 were anterior STEMI. Like admission ECG, after 90 minutes of starting thrombolytic,another ECG was recorded and calculated. Echocardiography was done for each patient before discharge. Data was collected in a pre-designed form.\u0000Results: The mean age of Group-I was 55.2±12.2 years and that of Group-II 56.9±14.1 years, Group-III 59.2±11.7 years,Group-IV 55.0±12.6 years. Of the 30 patients studied in Group-I 76.7% was male and 23.3% female. Smoking was the most prevalent (60% in Group I, 58.8% in Group II) risk factor. In post thrombolytic ECG shows that in Group-I mean sum of ST elevation decreased to 3.9 ± 1.1 mm from 4.8 ± 1.2 mm. which was approximately (45+14)% of ST resolution, in Group-II(50+19%),in Group-III (55+19)%, in Group-IV(45+23)%.\u0000Conclusion: Significant differences were seen in chest pain, killip class,arrhythmia, echocardiographic LVEF, duration of hospital stay in patients with AWMI & STSS above 12 mm and IWMI & STSS above 7 mm in comparison with below these level even after use of thrombolytics.\u0000Medicine Today 2022 Vol.34(2): 88-92","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82712898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Maternal & Fetal Factors in Relation to Low Birth Weight","authors":"Tasnuva Islam, Abdullah Al Mahboob, F. Ahammad","doi":"10.3329/medtoday.v34i2.61423","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61423","url":null,"abstract":"Introduction: Low birth weight (LBW) continues to remain a major public health problem worldwide. There are numerous factors contributing to LBW both maternal and fetal. The mortality of low birth weight can be reduced if the risk factors are detected early and managed by simple techniques.\u0000Objective: To identify the maternal and fetal factors associated with low birth weight.\u0000Materials and Methods: This case control study was conducted in Department of Pediatrics, Khulna Medical College& Hospital from January 2019 to June 2019. After delivery of the baby weight of the newborn was measured with digital weighing scale. Mothers of babies with birth weight <2500 gm were enrolled as cases and mothers of babies with birth weight _2500 gm were enrolled as controls.\u0000Results: Total 96 mothers were enrolled in this study and 48 mothers in each group. All the information was recorded in a pretested questionnaire. Statistical analysis was done by SPSS. Primipara mother had 3.153 times more likely to deliver LBW baby. Patients having anemia had 3.316 times more likely to deliver LBW baby. Patients having hypertension had 4.120 times more likely to deliver LBW baby. Preterm delivery had 28.927 times more likely to deliver LBW baby. Primipara, anemia, hypertension and preterm delivery were significantly associated with LBW. In multivariate analysis, preterm had 20.619 times more likely to deliver LBW.\u0000Conclusion: Primipara, anemia, hypertension and preterm delivery were significantly associated with LBW.\u0000Medicine Today 2022 Vol.34(2): 106-110","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82761042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Uncommon Presentation of Choronic Osteomyelities of Humerus Using Ilizarov Technique in a 2 Years Old Child: A Case Report","authors":"Chowdhury Foyzur Rob, Md Gulam Mustofa, SM Shahnewaj, Md Akhlas Bhuiyan, Tanvir Ahmed, Saoud Ahmed, H. Rahman","doi":"10.3329/medtoday.v34i2.61435","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61435","url":null,"abstract":"Introduction: Chronic osteomyelitis is a surgical disease that can require significant dedication from both patient and surgeon to eradicate. Treatment requires isolation of pathogen, significant debridement for removal of all infective and necrotic material, then bony and soft tissue reconstruction.\u0000Objective: We shall try to highlight the option of management of a pan-Diaphyseal osteomyelitis of a children in the new era of osteosynthesis by Ilizarov.\u0000Discussion: A two years old baby presented to us with the H/O chronic discharging sinus and arm sling for around 3 months. After clinical history taking and examination, radiography and pus testing (C/S) and sequestrum and pathological fracture was the identifying points we took the plan for exploration curettage and drainage. Finally we fix the arm by Ilizarov osteosynthesis for more than 3 months. The wound healed and osteomyelitis resolved.\u0000Conclusion: Use of Ilizarov osteosynthesis for fixation and wire tension effect to resolve the infection1,2\u0000Medicine Today 2022 Vol.34(2): 157-158 ","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77170280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic Study of Dermatological Manifestations of DM Patients Attending in a Medical College Hospital","authors":"Sk Mamun Ar Rashid, Ratan Lal Dutta Banik, Sharup Chandra Poddar","doi":"10.3329/medtoday.v34i2.61432","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61432","url":null,"abstract":"Introduction: Diabetes mellitus (DM) is a common metabolic disorder and is significant for its ability to adverse effect of various organs. Skin manifestations in this condition are due to metabolic derangements, chronic complications and infections, which are commonly observed after developing clinical diabetes mellitus, but may also precede the disease.\u0000Aim: The aim of this study was to understand dermatological manifestations in diabetes mellitus relation with demographic parameters.\u0000Materials and Methods: It was a hospital based cross sectional study carried out among 80 randomly selected diabetic patients with/without skin lesions. Patients were then asked for their willingness to participate in the study. Skin examination was carried out and skin lesions were identified. All data was recorded in the pre-designed, pre-tested, and semi-structured questionnaire developed for the study. Data was analyzed using SPSS version 26. Frequencies and percentages were calculated for the necessary data.\u0000Result: : Mean age of the subjects was 51.0±13.2 years, minimum age 25 and maximum 80 years. It was observed that, out of 80 patients, 52 (65.0%) were aged between 41–60 years. 52 (65%) were female and 28(35%) were male patients. 46(57.5%) were housewives and 16(20.0%) were service holders, 10(12.5%) were farmers and other 8(10%). 41(51.2%) from middle class, 38(47.5%) from lower class and 1(1.3%) were from upper class. 61.2% patients came from rural area and 38.8% patients from urban area. The mean duration of diabetes mellitus was 6.6±5.1 years, 42.5% patients duration had 5-10 years followed by 36.3% below 5 years and 21.3% patients had DM more than 10 years. Out of 80 patients, a total of 39(48.8%) DM patients had skin manifestations and 41(51.2%) had no skin manifestations. Among 39 DM patients with skin disease, 19(48.7%) having a single, while 8(25.5%) had two and 13(30.8%) patients had three or more skin lesions. 22(56.4%) patients found diabetic dermopathy, diabetic foot ulcer 12(30.8%), fungal infections 9(23.1%), bullous lesions 7(17.9%), diabetic foot gangrene 5(12.8%), lypodystrophy 5(12.8%), pruritus 5(12.8%), xerosis 5(12.8%) cases, scleredema 3(7.7%), ichthyosis 2(5.1%) and bacterial infections 2(5.1%). Age, sex, educational level, socioeconomic status, residence found no significant association (p>0.05), but duration of diabetes mellitus was significantly associated with the presence of dermatological manifestations (p=0.001).\u0000Conclusion: The spectrum of skin manifestations due to DM in this study population is similar to that in other parts of the world. Diabetic dermopathy, Pruritus and fungal infections are the most common cutaneous manifestations in DM patients. The presence of skin manifestations can highlighten the suspicion for DM enabling early diagnosis and management and thereby can be helpful for preventing complications.\u0000Medicine Today 2022 Vol.34(2): 145-149","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72802370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Extra-Cranial Carotid Arteries by Digital Subtraction Angiogram (DSA) in Stroke Patients in a Tertiary Care Hospital","authors":"Reza Nasim Ahmed, Most Mahmuda Begum, Md. Abdur Rashid, M. S. Azam, Mst Fatematujjahura, Md Raseul Kabir","doi":"10.3329/medtoday.v34i2.61426","DOIUrl":"https://doi.org/10.3329/medtoday.v34i2.61426","url":null,"abstract":"Introduction: Carotid artery stenosis is one of the important causes of ischemic stroke. This may be diagnosed by Doppler Ultrasound and Digital Subtraction Angiogram (DSA) both of which have some advantages and disadvantages.\u0000Objective: The aim of this study was to assess extra-cranial carotid artery with the help of DSA among patients of ischemic stroke and transient ischemic attack (TIA).\u0000Materials and Methods: This observational cross sectional study was conducted in the Department of Neurology in Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka from July 2013 to June 2015 for a period of two years. This study included a total of 50 patients. Diagnostic performance test of DSA was done at 50%, 50-69%, 70-99%, 100% cut off point of stenosis of right internal carotid artery (RICA) and Left internal carotid artery (LICA).\u0000Results: The mean age of cases was 61 ± 11.42 years. Out of 50 vessels, maximum cases were diagnosed as <50% stenosis of carotid artery (26 cases of RICA, 23 cases of LICA. Out of 50 vessels, 50%-69%, 70 but _ less than near occlusion and total occlusion were found among 10, 10, 4 vessels in RICA and 10, 9, 8 vessels in LICA respectively. The present study showed that 50 vessels of RICA was measured by DSA and diagnosed 28 (56%), 10 (20%), 7 (14%) and 5 (10%) carotid vessels as _ 50%, 50-69%, _70% but less than total occluded and total occluded cases respectively. This study also showed that 50 vessels of LICA was measured by DSA and diagnosed 23 (56%), 12 (24%), 8 (16%), 7 (14%) carotid vessels as _ 50%, 50-69%, _ 70% but less than total occluded and total occluded cases respectively.\u0000Conclusion: DSA as the gold standard has amply been performed in most diagnostic circumstances of carotid artery stenosis. So, the present study was done to evaluate extra cranial carotid arterial system by DSA in stroke patients in Bangladesh.\u0000Medicine Today 2022 Vol.34(2): 121-124","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72819362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Exposure of Cement Dust on Platelet Count in Workers of a Cement Mill","authors":"Rahnuma Ahmad, Q. Akhter, Mahmuda Abira, F. Rahman, Suparna Bhowmik, Farhana Hussain Sadia, T. Akter","doi":"10.3329/medtoday.v34i1.58674","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58674","url":null,"abstract":"Introduction: Cement dust is emitted during the different steps of cement production. This dust is composed of chemical components that may have unfavourable effects on the haematological system. The workers in these factories are exposed daily to this toxic dust. Those exposed to the cement dust may suffer from changes in platelet count and eventually suffer from damaging effects on the cardiovascular system.\u0000Objective: Assess the effects of cement dust on platelet count of cement mill workers.\u0000Materials and Methods: Conduction of this cross sectional study took place in the Department of Physiology, Dhaka Medical College, Dhaka between July 2017 to June 2018. After fulfilling the ethical consideration, 46 apparently healthy male cement mill workers, working for 2 or more years in a cement mill , with range of age of 20 to 50 years (study group) and 46 BMI, age and socioeconomic condition matched apparently healthy male subjects from Dhaka city were control group. The platelet count was estimated using automated haematology analyzer in Dhaka Medical College Hospital, Dhaka. Data was collected in a pre-designed structured questionnaire form. Unpaired Student’s ‘t’ test and Pearson’s correlation coefficient test were performed for statistical analysis.\u0000Results: In this study, the platelet count was significantly (p < 0.05) higher than those of control group. The platelet count was directly related with duration of cement dust exposure.\u0000Conclusions: This study concludes that the cement dust has harmful effect on the platelet count and the duration of exposure to cement dust also has an effect on this parameter.\u0000Medicine Today 2022 Vol.34(1): 44-46","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78938045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteriological Profile and Their Antimicrobial Susceptibility Pattern of Urinary Tract Infection Patients Attending at the Nephrology Department of Enam Medical College and Hospital, Savar, Dhaka.","authors":"Md Shamimur Rahman, M. U. Ahmed, Bhuiyan Mohammad Mahtab Uddin, R. K. Chowdhury, Harun Ur Rasid, A. Begum","doi":"10.3329/medtoday.v34i1.58677","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58677","url":null,"abstract":"Introduction: Urinary tract infection (UTI) is one of the common bacterial infections encountered by clinicians in clinical practice. Distribution and susceptibility of UTI-causing pathogens change according to time and place. Area-specific studies to gain knowledge about the type of pathogens and their resistance patterns may help the clinician to choose the proper antimicrobials for empirical treatment.\u0000Objective: This study was conducted to determine the distribution and antimicrobial susceptibility of uropathogens.\u0000Materials and Methods: This study was conducted in the Enam Medical College & Hospital, savar, Dhaka between January 2021 to June 2021 to identify the organisms causing UTI and their antibiotic susceptibility. Clean catch midstream urine samples were collected from 476 clinically suspected UTI patients and tested bacteriologically using standard procedures. Antimicrobial susceptibility test was performed by Kirby-Bauer disk diffusion method.\u0000Results: The prevalence of UTI was higher in females than in males. Out of the 170 culture positive bacterial isolates Escherichia coli was the most common 51.76% organism, followed by Staphylococcus aureus 28.82%, Staphylococcus saprophyticus 11.17%, Klebsiellaspp 8.23 % and Enterococcusspp 4.70%. Meropenem (100%) followed by Imipenem (92.86% to 100%) were found most susceptible drugs. While Trimethoprim-sulfamethoxazole and Cephradine were the most resistant drug against the isolated uropathogens.\u0000Conclusion: As bacterial drug resistance is an evolving process, routine surveillance and monitoring studies should be conducted to provide physicians knowledge on the updated and most effective empirical treatment of UTIs.\u0000Medicine Today 2022 Vol.34(1): 51-56","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81041259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}