Medicine Today最新文献

{"title":"Laparoscopic versus Open Appendicectomy in a District Hospital","authors":"M. Islam, Sm Golam Azam, Md. Showkat Ali, Md Ridwanul Islam","doi":"10.3329/medtoday.v34i1.58672","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58672","url":null,"abstract":"Introduction: Appendicitis is one of the most common clinical conditions requiring surgical intervention in day-to-day practice, which is indicated for both acute appendicitis and recurrent acute appendicitis. Appendicectomy can be performed using several surgical techniques like laparotomy (open), laparoscopic appendicectomy.\u0000Materials and Methods: We have done 110 cases in one year from July 2019 to June 2020.\u0000Results: Out of the 110 patients, 42 (38%) underwent laparoscopic surgery and 68 (62%) open appendicectomy.\u0000Conclusion: Female are predominant than male patients. Postoperative hospital stay, postoperative complications like wound infections are much less in laparoscopic procedure. The acceptance of laparoscopic appendicectomy gradually increases among the surgeons as well as the patients.\u0000Medicine Today 2022 Vol.34(1): 36-38","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90162410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraceptive Methods Used by the Selective Rural Tea Garden Workers of Sylhet","authors":"R. Jahan, Md Monjurul Habib Choudhury, Asm Mashrurul Haque, Md Oliur Rahman Chowdhury, S. Chowdhury, Progya Laboni Tina","doi":"10.3329/medtoday.v34i1.58683","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58683","url":null,"abstract":"Introduction: This study was focused on contraceptive methods used by the selective Tea garden workers of Sylhet. The aim was to explore the used of the contraceptive methods and factors influencing the use of the contraceptive methods along with socio-demographic profile of the tea garden workers.\u0000Materials and Methods: It was descriptive type of cross-sectional study carried out in some selective tea garden of Sylhet from July-December, 2020. 150 respondents were selected by purposive type of non-probability sampling method. Data were collected by a pretested mixed type questionnaire.\u0000Results: The study revealed that 90 (60%) of workers belonged to of 20-29 years age group. The mean age was 33.87 ± 8.97. Most of the respondents 104 (69.3%) were female, 117 (78%) were followers of Hinduism, 109 (72.7%) were illiterate, 136 (90.7%) were from the nuclear family and 129 (86%) were belonged to lower class. Majority of the workers 136 (90.7%) were using contraceptive methods, among them 78 (57%) were using injectable contraceptive but no one use permanent methods. Most of them used contraceptive methods for prevent unwanted pregnancy and reduced family expenditure that was 46 and 40 (34% and 29%). The survey assessed the positive association between use of contraceptive methods and sex, religion (p<0.05).\u0000Conclusion: Due to covid situation, the present study was conducted among only 150 respondents. Large scale survey is necessary to find out the exact pattern of contraceptive methods use throughout the tea garden workers.\u0000Medicine Today 2022 Vol.34(1): 79-82","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"14 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80415697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Oral Candidiasis among Children Caused by Different Candida Species","authors":"Tanzila Rawnuck, Md. Selim Reza, R. Ahmed, Mohammad Fatteh Ul Islam, Abm Iftekhar Hossain, N. Sultana, S. Monwar","doi":"10.3329/medtoday.v34i1.58678","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58678","url":null,"abstract":"Introduction: Oral candidiasis, which is caused by Candida species by the involvement of hard and soft palates, tongue, buccal mucosa, and floor of the mouth, is becoming a very common threat to oral health. Although in the majority of the cases, this infection is caused by Candida albicans which is a normal commensal organism in humans, however, it might be also caused by other Candida species, such as C. glabrata, C. tropicalis, and C. krusei.\u0000Objectives: This study aimed to evaluate the prevalence of oral candidiasis among children and to compare the type of causative candida species among them.\u0000Materials and Methods: This prospective observational study was conducted in the Shishu Hospital, Shamoly, Dhaka, spanned January 2016 through December 2016. A total of 286 oral swab samples were collected, and three methods including direct wet mount smear, staining, and culture were used for laboratory investigation of Candida infections.\u0000Results: Among 286 respondents, 161 (56.29%) were culturally and microscopically confirmed to have oral candidiasis. Among all of the detected species, C. Albicans was by far the highest species with 139(86.34%) followed by C. tropicalis with 14 (8.68%). Whereas 05(3.12%) cases were infected by C. krusei. On the other hand, the least detected species were C. glabrata and C. guilliermondii with 01(0.62%) and 02(1.24%) respectively.\u0000Conclusion: These days accurate and prompt identification of the infectious candida strains is crucial because isolates of Candida species differ extremely, both in their ability to produce infection and also in their susceptibility to antifungal agents.\u0000Medicine Today 2022 Vol.34(1): 57-60","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87973832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Laparoscopic Cholecystectomy in Acute Calculous Choleycystitis – Analysis of 100 cases","authors":"Md Ahad Ali Mahalder, Md Joynal Abeden, Rehnuma Karim, M. Islam","doi":"10.3329/medtoday.v34i1.58673","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58673","url":null,"abstract":"Introduction: Gallbladder disease is one of the most common surgical problems worldwide. About 10-15% of the adult western population has gallstone diseases . More than half a million cholecystectomies are performed per year in United States alone. Laparoscopic cholecystectomy (LC) is currently the most widely used surgical procedure for the treatment of gallstones.\u0000Aims and Objectives: To observe the cause of difficulties, the sequele , identify and find out the nature & rate of per operative complications and find out the type & frequency of early post-operative complications following laparoscopic cholecystectomy in acute calculous cholecystitis.\u0000Materials and Methods: This is a prospective interventional study which was conducted at Jashore Medical College Hospital & some clinics of the city from Sept 2019 to Feb 2020. A total of 100 patients underwent Laparoscopic cholecystectomy for acute calculous cholecystitis within 7 days of admission.\u0000Results:Among 100 patients, 80 females & 20 males with maximum age group were in the fourth decade, Laparoscopic cholecystectomy was done in 97 (97%) cases & in 3(3%) cases conversion were needed, none of the patients were developed major Per & postoperative complications. Peroperative complication rate was 22 (22%) with conversion was 03(3%) cases. All of the above complications were managed accordingly & successfully.\u0000Conclusion: Laparoscopic Cholecystectomy is a safe, effective procedure for the early management of patients with acute calculus cholecystitis. Meticulous dissection & good exposure of callot’s triangle, posterior clearance may prevent bile duct injuries.\u0000Medicine Today 2022 Vol.34(1): 39-43","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"694 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76884333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteriology and Antibiotic Sensitivity Pattern of Sputum in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease","authors":"M. I. Majumder, Pinki Shaha, Mostaque Ahmed, M. N. Uddin, Mahabubur Rahman, T. Ahmed","doi":"10.3329/medtoday.v34i01.58632","DOIUrl":"https://doi.org/10.3329/medtoday.v34i01.58632","url":null,"abstract":"Introduction: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality worldwide. Nowadays investigators need culture studies for proper selection of antibiotic, but it is a time consuming process. The choice of the antibiotic should be constituted on the bacterial sensitivity and resistance pattern.\u0000Objective: To identify the causative bacteriology and antibiotic sensitivity of sputum of chronic obstructive pulmonary disease patients with acute exacerbation.\u0000Materials and Methods: It was a prospective study in department of medicine Cumilla Medical College Hospital during the period of July 2019-2020. All the patients included in this study were above 37 years of age, diagnosed as acute exacerbation of COPD (AECOPD) were included in this study. Those patients were on antibiotic was advised to stop antibiotic for 48 hours and were included in this study. Fresh spot specimen as well as overnight collection of sputum samples were collected from each 257 patients of different age and sex groups in a sterile screw capped universal container. The specimen was labeled and transported to the microbiology laboratory for processing and cultured within half an hour of collection. Antibiotic susceptibility pattern was done following Kirby-Bauer disc diffusion method of clinical laboratory science (CLS) program.\u0000Results: Majority (45.5%) of the patients had growth of Klebsiella pneumoniae. All the isolated organisms except Acintobactor are mostly sensitive to Meropenum, Imipanum and Amikacin. In vitro sensitivity pattern against these antibiotics was more than 85%.\u0000Conclusion: Male is predominating and majority of them are older age group. Klebsiella pneumoniae, Pseudomonas and E. coli are common isolated organisms.\u0000Medicine Today 2022 Vol.34(1): 12-16","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80438513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laboratory Parameters of Dengue Infection in a Medical College Hospital","authors":"Sabikun Nahar Chowdhury, Md. Nazrul Islam, Mahabubur Roshed, Mokter Hossain, S. Saha","doi":"10.3329/medtoday.v34i1.58679","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58679","url":null,"abstract":"Introduction & objective: Dengue is an acute illness caused by Aedes mosquito, commonly caused by Aedes aegypti. It is an endemic disease in South East Asian countries especially in Bangladesh. In 2019 a outbreak occurred in Bangladesh. The objective of the study was to see the laboratory parameter and outcome of dengue fever in a tertiary medical college hospital. Early diagnosis and laboratory investigations is essential to prevent the mortality associated with this disease.\u0000Materials & Methods: This prospective study was conducted on dengue ward at Khulna medical college hospital from 1 July 2019 to 31 December 2019. The diagnosis of dengue infection was confirmed by serology. Sera were processed by dengue ELISA. Investigations like haemoglobin estimation, haematocrit, platelet count, total count; differential leukocyte count, peripheral smear, coagulation profile were performed.\u0000Results: Total number of cases was 98. Of them 62 (63.2%) was male and 36 (36.73%) was female. Fever was most common (100%) manifestation and duration of fever ranges from 5 to 8 days with a mean duration of 6.31 (± 0.95) days. Blood for NS1 was positive in 90 (91.83% ) cases; most cases 71 (72.44%) become positive between 2nd to 4th day. 90 (91.83%) cases developed thrombocytopenia and it starts at 5th day in 45 (45.91%) cases. Anti IgM was positive in 4 (4.08%) cases; 2 at 4th day and 2 at 5th day of illness. IgG was positive in case at 8th day of illness.\u0000Conclusion: These findings help physicians in early diagnosis of dengue by suspecting these features as of dengue and can prevent morbidity and mortality associated with dengue.\u0000Medicine Today 2022 Vol.34(1): 61-64","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84824535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteriological Profile of Suspected Neonatal Septicaemia and Its Relationship with Selected Risk Factors","authors":"Md. Shamsul Alam, Sanaul Haque Mia, Md. Belal Uddin","doi":"10.3329/medtoday.v34i01.58669","DOIUrl":"https://doi.org/10.3329/medtoday.v34i01.58669","url":null,"abstract":"Introduction: Neonatal septicaemia is one of the major problem in neonatology with a high case fatality rate. Manifestations of neonatal septicaemia are subtle & non-specific. Blood culture is the “gold standard” in the diagnosis of neonatal septicaemia, a high index of suspicion with or without laboratory evidences of infection is the key for early diagnosis. Early diagnosis & introduction of antibiotic may reduce mortality and morbidity.\u0000Objective: To explore the bacterial organisms among the suspected neonatal septicaemic cases and its relationship with selected risk factors.\u0000Materials and Methods: A Cross sectional descriptive type of study was carried out on all suspected cases of neonatal septicaemia patients admitted in the paediatric wards of Rajshahi Medical College Hospital during the period of july 2008 to june 2010 .Total 60 sixty cases who had non- specific symptoms of septicaemia were enrolled in this study. After a clinical evaluation and management of the patient blood culture was performed on all neonates with risk factors or signs suggestive of sepsis.\u0000Results: Out of sixty cases of suspected neonatal septiceamic newborns 18.33% were culture positive for bacteria. Both gram negative and gram positive bacteria were responsible for neonatal septicaemia. Majority of the organisms were gram negative (54.5%) and most common organisms was E.coli (54.5%) .Other gram-positive organisms were streptococcus spp(27.3%) and staph aureus(18.2%) respectively. Among blood culture positive cases 82% were early onset neonatal septicaemia & 18% were late onset septisaemia. Gestational age, Low birth weight, Low socioeconomic status of mother, mode of delivery and birth asphyxia were risk factor for both early onset neonatal sepsis & late onset neonatal sepsis.\u0000Conclusion: Septicaemia is one of the major causes of death & its manifestations are subtle and non specific. Both gram negative & gram positive bacteria are responsible for neonatal septicaemia. Most isolated bacteria E.coli. Risk factors may be the factor for NNS. Although blood culture is the “gold standard” in the diagnosis of NNS, a high index of suspicion with or without laboratory evidences of infection is the key for early diagnosis. If we can avoid risk factors for NNS by antenatal check up of pregnant mother and thereby number of septicaemia could be reduced.\u0000Medicine Today 2022 Vol.34(1): 17-21","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77171201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stroke and Coronary Heart Diseases, Global and Asian Trend and Risk Factors -A Perspective","authors":"Sk Mamun Ur Rashid, S. Hossain","doi":"10.3329/medtoday.v34i1.58671","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58671","url":null,"abstract":"Introduction: Cardiovascular disease (CVD) is the leading cause of death in the world, accounting for 30% of deaths globally. CVD is a group of conditions affecting the functions of the heart, blood vessels or both. The major cardiovascular diseases include coronary heart disease (CHD), stroke, hypertension, heart failure and peripheral vascular diseases. Distribution of CHD and stroke is different in different regions of the world, especially western high-income, Asian and other countries. The Asian prevalence also not homogenous. Estimated number of deaths due to CVD worldwide will projected to 23.4 million, comprising 35% of all deaths in 2030. Significant increase in prevalence of coronary heart diseases (CHD) have been observed in the Asia including Bangladesh, but stroke in some regions of the world. Objectives: (1) Identification of cases and risk factors in different geographical area (2) Reduction of morbidity and mortality by proper treatment and management of modifiable risk factors.\u0000Materials and Methods: This observational study was done through using evidence from the published study articles of CVD in national and international journals, electronic databases such as MEDLINE, EMBESE and PUBMED. We also manually checked references of relevant publications of stroke and CHD.\u0000Study period: Jan2019-Dec2019.\u0000Results: Approximately 940 million people in the high income countries, where CHD is the dominant form of CVD which is 2–5 times higher than stroke. In the USA, Canada, Australia, New Zealand, Italy, France and Spain CVD death rates are very low. The highest death CHD rate is in Finland, Ireland, Scotland, Norway, Sweden of the European countries. In Eastern Europe and most of the Asia, the rate of coronary arterial diseases are rapidly increasing. Japan the Asian high income country the death ratio of stroke and CHD is 3:1.The East Asia and the pacific including China CVD is the major cause of death, where stroke dominating. People in South Asia including India and Bangladesh the coronary diseases are increasing alarmingly, where CVD death increase 30%over the preceding decade and the dominant form is CHD. In the central Asia, specially Uzbekistan, Kazakhstan, Tajikistan both CHD and stroke are very high. In Latin America death from CHD (35%) higher than stroke (29%). In the Middle East and North Africa, CHD responsible for 17% and stroke 7%of all death.\u0000Conclusion: Asian countries have disproportionately high morbidity and mortality from stroke with increasing tendency to CHD, but CHD in Western countries which may be due to complex interaction of genetic and environmental factors, smoking, hypertension and metabolic abnormalities. Death rate is higher in male sex from both CHD and stroke worldwide.\u0000Medicine Today 2022 Vol.34(1): 27-35","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87485747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrum of Haematological & Non Haematological Disorder Diagnosed by Bone Marrow Examination: A Study of 115 Cases","authors":"S. Reshma, Salina Haque, Zulfia Zinat Chowdhury, Mohammad Iqbal Kabir, M. Rabbani, Md Atiqul Islam Rabby","doi":"10.3329/medtoday.v34i01.58631","DOIUrl":"https://doi.org/10.3329/medtoday.v34i01.58631","url":null,"abstract":"Introduction: Haematological and nonhaematological diseases affecting the bone marrow may be primarily or a secondarily spread to the marrow. In most of the cases, diagnosis can be arrived at by a detailed history, physical examination and few simple investigations. Bone marrow examination is a very useful tool in the diagnosis of hematological and non-hematological diseases.\u0000Materials and Methods: This retrospective study was done in the department of haematology, in a specialized diagnostic centre from July 2018 to July 2021. A total of 115 cases were included in this study. Clinical parameters were assessed, peripheral blood smear along with necessary haematological investigations were done.\u0000Results: Majority patient were male (70%). In total cases 44.4% patients were under 30 years of age. Among them 23(20%) were under 10 years. The most common indication for bone marrow examination was diagnosis & management of Acute Leukaemia 27(23.48%), Major presenting complaints were fever 49(42.61%), fatigue 46(40.0%) & bleeding manifestation 22(19.13%). On systemic examination, pallor was found in majority of the cases. Hematological malignancies were found in 77(66.96%) cases, non-malignant haematological disorders were found in 33(28.70%) cases. Acute leukaemic condition (ALL, AML) were the most common malignant conditions, 22(19.13%) & 17(14.78%) respectively. Most common nonmalignant haematological conditions were hypocellular marrow 17(14.78%).\u0000Conclusion: Acute Leukemia is a major indication of BME. Among the pathological condition malignant condition are commonly seen. And male are predominantly suffering more from haematological disorders than female. In majority cases acute leukaemic condition are seen in BME.\u0000Medicine Today 2022 Vol.34(1): 7-11","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88398366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid Function Status during Different Trimesters in Bangladeshi Women","authors":"S. Banik, M. Begum, Farjana Ahmed, M. Shamsuzzaman, K. Saha","doi":"10.3329/medtoday.v34i1.58675","DOIUrl":"https://doi.org/10.3329/medtoday.v34i1.58675","url":null,"abstract":"Introduction: Gradual alteration of thyroid function occurs during different trimesters of gestation.\u0000Objective: To observe thyroid function status in normal pregnancy.\u0000Materials and Methods: This cross sectional study was conducted in the Department of Physiology, Sir Salimullah Medical College, Dhaka from July 2016 to June 2017. The study was approved by Institutional Ethical Committee. Total 120 female subjects, age ranged from 20 to 35 years were included in this study, among them 90 were healthy pregnant women and 30 were nonpregnant women. Serum TSH, FT4 & FT3 levels were measured. The statistical analysis was done by ANOVA test and Bonferroni test.\u0000Results: In this study, mean serum TSH level was lower in 1st & 2nd trimester and higher in 3rd trimester than that of nonpregnant group. Again it was gradually higher from 1st to 3rd trimesters of gestation and the difference was statistically significant (p<0.05, p<0.001, p<0.01) in between the groups. Mean serum FT4 & FT3 levels were higher in 1st trimester and lower in 2nd & 3rd trimesters of gestation than that of nonpregnant group. Again, both these levels were gradually lower from 1st to 3rd trimesters of gestation and the difference was statistically significant (p<0.001, p<0.001, p_0.01) in between the groups.\u0000Conclusion: Gradual alterations of thyroid function status were observed during pregnancy. Serum TSH level was gradually higher and both serum FT4 & FT3 levels were gradually lower from 1st to 3rd trimesters of gestation.\u0000Medicine Today 2022 Vol.34(1): 47-50","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88419129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}